LOCUS       BGC0001645              5609 bp    DNA     linear   CON 13-JAN-2022
DEFINITION  Streptomyces sp. NRRL S-118 P205_Doro1_scaffold34, whole genome
            shotgun sequence.
ACCESSION   BGC0001645
VERSION     BGC0001645
KEYWORDS    .
SOURCE      Streptomyces sp. NRRL S-118
  ORGANISM  Streptomyces sp. NRRL S-118
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            KL591029.1.
            Bacteria available from NRRL.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 03:08:12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 29464
            Orig. end    :: 35073
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..5609
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="RiPP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..5609
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            746..859
                     /locus_tag="IH00_RS42245"
     CDS             746..859
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="IH00_RS42245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_107064568.1"
                     /transl_table=11
                     /translation="MTMAYERPTLTKVGDFQKVTGLAGQGSPDLLGGHSLL"
     gene            1209..2879
                     /locus_tag="IH00_RS0132710"
     CDS             1209..2879
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 113.3; E-value: 2e-34)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655084.1"
                     /locus_tag="IH00_RS0132710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_234335044.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-39, bitscore:
                     125.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGQHAVTEREAARAAGAGSPGAAERLARTWPGSHHLLASFDGEI
                     LALGTVTGVRSLFVASARGAGGACVAADRADVLAGLVDAELDEGRLAVHLLSPGILHPL
                     TAQTVWRGVDVVPGDHRLTLDRDGHARTSRHWAPPPAELSLAEGARLVRDRLADAVAVR
                     VAGGGPVTADLGGVDSTAVVCTAARQGAKMVAYTAAVHDVLGDDVTYAQRTAEALDSLE
                     HHVVPATAVPLTFDGVHELDDALDTPSLYSVNRHRRMYIIERAAERGSSLHLSGMGGDE
                     LFSGASAHVHGLLRRHPRTGWRHTRGFVTRHRWSRRTALRQLLDGRSYGAWLDQVARDL
                     TLPQPPMSVPLFEWGTPPRLPPWATGRAVEAVRDLIRTQAPQAEPLGSGHGVHRELATM
                     RTLARFARHVQQMSEPLGITFASPYYDDLLIEAALAVRPQERVTPWRYKPLIEEAMRGV
                     VPDASRRRTTKAHAAFEEETGLRRHRSSLLALWNDAHLHGLGLIDVEAVRAWCRRPLAA
                     DLESALLHATVGCEVWLRSRENSAGRRGRPRTDTGGIPA"
     gene            2876..3133
                     /locus_tag="IH00_RS0132715"
     CDS             2876..3133
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986678.1"
                     /locus_tag="IH00_RS0132715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_031079703.1"
                     /sec_met_domain="PF05402 (E-value: 5.3e-20, bitscore: 60.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.3e-28,
                     bitscore: 86.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.4e-10, bitscore:
                     29.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMTLRPGVVTADTEYGMALLDQSSGEYYTLNPTAAVIVRALLDG
                     TTTDQAVTALTDQYDVSAEQVEEDIARILQELRDARLLTG"
     gene            3273..3689
                     /locus_tag="IH00_RS0132720"
     CDS             3273..3689
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047207.1"
                     /locus_tag="IH00_RS0132720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_031079704.1"
                     /sec_met_domain="PF13471 (E-value: 2.3e-28, bitscore: 87.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSQVVPHDPRSVPLGRRLVTRLVVVCAHVLARRSPAGIRDVLR
                     WLRKGARPATLAEAARARETVLAVSLAAGGQQGCLARSLATVLLCRLRGQWPTWCVGVR
                     TQPPFAAHAWVEAEGVLVGEGAPADYFQRFFTVD"
     gene            3696..5609
                     /locus_tag="IH00_RS0132725"
     CDS             3696..5609
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 355; E-value:
                     1.3e-107)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432755.1"
                     /locus_tag="IH00_RS0132725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="WP_234335045.1"
                     /transl_table=11
                     /translation="MTPSPSPSPYFAKPPLRPPAPGPADRRAQSVLAGEESSVPPRHGP
                     SGSPAAGGARPGTGVRDERTRPWHVLTHLRPHRPGILLGSALSLAGSLLALAQPLVAKQ
                     MVDALDRGRPAAGALVLLSALVVAGAATAALGQYVLERTAESVACTARRRLSERLLRLR
                     LPVLNRTEPGELISRVTSDTTVLRQVATRSIASAGSGLLVVVATLALMALLDPVLLSIT
                     LVTIALIGATVAAAVPHIARAARQAQEAVGRMGSLLERTLGAVRTIKASGAEGRETAGL
                     HQAAEDARRAGTRAARWQALSATTSTVAVQLSFLVVLGVGGARVATGAITVSTLVAFLL
                     YVFALAPRVGQLVEAVGLLQAGAAASARIGEVHSMDTEPVGPHQAPATTPEPRRPVGVV
                     FQGVRFSYGPEAPPVHEDVTFTVPPKTTTALVGPSGAGKTTVFSLLERFYQPDRGRILL
                     DGEDIARLPLSRLRALIGYVEQDSPILSGTLRDNLLLSAPDADAAQVRDVLRRTRLDCL
                     VARLPDGLDTPIGHRGSTLSGGERQRVAIARALLRRPGLLLLDEATSQLDAANEAALHE
                     TLADISRTTTILVIAHRLSTVTTADQILLLESGRVRAAGTHAQLLAADAFYRRLAAAQH
                     LA"
ORIGIN
        1 gcgggcgggc tcatcgggcg gcttgcgggc cgcgctacat aggggtgggg gccggcaatg
       61 gccgtcccga cgcgtggcac gcacctcgcc ggagtccgtg gcgaacccgg ttcggcgagg
      121 cacggggcgt cggcgcgtga tgaaggacgg tgctccagtg tgacgctctt tacatcgcgg
      181 aggtcgtgga ggatggtcgt gtctccttcc gctcctccgt gcagacggcg cgtaagggcg
      241 cagtgaacgt ctggtgttcc cgccggatgc acgcggcgct cttctcctgc ggccggcgag
      301 gggtacgtcg tgttttctgt gagccggaca cacgcaagtg cgcattccag gacggcgggg
      361 gagggggtgg ccggatcgac ttcgctccgg cacggcctca cggtccgtcg ccgcaggtca
      421 ggccggggag acagccgtaa atcgtgctgt cggggcccgc cgtacgtgtc tcgaaacgcg
      481 cgcgcccgca gaaagcggca tcgctgatac cccgactgcg caggatcatg accgaccgct
      541 cgtgccattt atgcaaatcc gcaggtgaag cacgcacgga atactgcgga agcgccttgc
      601 tgaatggctt gtgtgcgccg ttgccgcagg taatgcgcgc acctagcttt gtgcactgcg
      661 tcggcgagcc ccgctcgatc ctgccggggg cgccgactcg cgtacggaaa cagcaccagt
      721 ccagttcatc ccacaacgaa agggcatgac gatggcctac gaacgcccca ctctcaccaa
      781 ggtcggcgac ttccagaagg tcaccggact ggccggccag ggcagccccg accttctggg
      841 cggccacagc ctgctctgat ccggcccgcc catcggcccc gggcgatccg aacaccgacg
      901 gtacgtcccg gggcacgtcg ggtccgtagc gtgggcggcg taccgcgccg cccacgctcg
      961 tcccccgtac cgctgctgga accgcatcga ccaagagagg cctgtgcatg gcgaccggta
     1021 cgtcactgcc cccgggggcg agttggttcc tggtccttcc ggacaccgac gccgtcgcgg
     1081 ccctggccgc accggttcgc tcgcgtgcgg tacgggagat caggcatgcc tcgggccggc
     1141 cttggctgct ggggtgctgg ccggaggaca gtgtgacgac agcggtctgc ggacggaccc
     1201 ggttgtgcgt gctgggacag cacgcggtga ccgagcggga ggcggcgcgt gcggctggcg
     1261 ccggatcccc gggagcggcc gagcggctcg cccgtacctg gcccggcagt caccatctgc
     1321 tcgccagctt cgacggcgaa atcctggctc tcggcaccgt caccggcgta cgcagcctct
     1381 tcgtggcgtc ggcccgtggc gcgggcggtg cgtgcgtcgc ggccgaccgc gccgacgtcc
     1441 tggccggcct ggtcgacgcg gagctggacg agggccggct ggccgtccac ctgctcagcc
     1501 ccggaatcct gcaccccctg acggcacaga cggtgtggcg cggcgtcgat gtggtgcccg
     1561 gcgaccaccg cctgacgctc gaccgcgacg gacacgcccg tacgagtcgg cactgggcgc
     1621 cgccgccggc cgagctgtcg ctggccgagg gcgcacggct ggtccgcgac aggctggccg
     1681 acgcggtcgc cgtacgcgtc gcgggcggcg gaccggtcac cgccgacctg ggcggggtcg
     1741 actccaccgc ggtggtctgc accgcggccc gccaaggagc gaagatggtc gcctacacgg
     1801 ccgccgtcca cgatgtcctc ggcgacgacg tcacctacgc gcagcgcacg gcggaggcgc
     1861 tcgactcgct ggaacaccac gtggtgcccg cgaccgccgt acccctgacc ttcgacggcg
     1921 tgcacgaact cgacgacgcg ctcgacaccc cgtcgctgta ctccgtcaac cgccaccggc
     1981 gcatgtacat catcgagcgg gccgcggagc gtggctcctc gctgcacctg agcgggatgg
     2041 gcggggacga actgttcagc ggcgccagcg cccatgttca cggcttgctg cgccggcatc
     2101 ctcgtacggg ctggcggcac acccgcggct tcgtcacgag gcaccggtgg tcgcgccgga
     2161 cggcattgcg gcaattgctc gacggccgct cctacggggc ctggctggac caggtggccc
     2221 gcgacctcac gctgccccaa ccgcccatgt cggtacccct cttcgagtgg ggcaccccgc
     2281 cacggctgcc cccctgggcc accggccggg ccgtcgaggc cgtgcgggac ctcatccgta
     2341 cgcaggcccc gcaggcggag ccgctcggca gcggacacgg tgtgcaccgc gagctggcca
     2401 cgatgcgcac cctcgcccgc ttcgcccggc acgtacagca gatgtccgag cccctgggca
     2461 tcaccttcgc ctccccctac tacgacgacc tcctcatcga ggcggcgctc gcggtccgcc
     2521 cccaggaacg tgtgaccccc tggcggtaca agccgctgat cgaggaggcc atgcggggcg
     2581 tcgtacccga cgccagccgc cggcggacca ccaaggccca cgcggccttc gaagaggaaa
     2641 ccgggctgcg caggcaccgc tcctcattgc tcgccctgtg gaacgacgcc catctgcacg
     2701 gcctgggact catcgatgtg gaggccgtcc gtgcgtggtg ccgtcggcca ctcgccgcag
     2761 acctggagag cgcgctgctg cacgccaccg tcggctgcga ggtctggctg cgttcccggg
     2821 agaattccgc cggccgaagg ggccggcccc gaaccgacac aggaggcatc cccgcatgac
     2881 gatgaccctg cgccccggcg tggtgacggc cgacacggag tacgggatgg ccctgctcga
     2941 ccagagcagc ggcgagtact acaccctgaa ccccactgcc gccgtcatcg tgcgtgccct
     3001 gctcgacggc accaccaccg accaggcggt gaccgcgctc accgaccagt acgacgtgag
     3061 cgccgagcag gtcgaggagg acatcgcccg cattctgcag gagctgcgcg acgcccggct
     3121 gctgacgggg tgagtcctgg ctcgtcccgg cacgcgcctc gtcgccgtca ggcaccgccc
     3181 ggcgttctcg cgagagctgc ccggcccggc ttccgcccgt gtccgtcatc gtccgcggcc
     3241 cgcattcgtc gtcgtctccg aagggtagag cagtgtccac ctcgcaagtc gtcccgcacg
     3301 acccccggtc ggttccgctc ggccggcggc tggttacccg gctggtcgtc gtctgcgccc
     3361 atgtcctcgc acgccggtcc ccggccggta tccgcgacgt actgcggtgg ctgcgcaagg
     3421 gcgcccggcc ggcgacgctc gccgaggccg cccgtgcccg cgagacggtc ctcgccgtaa
     3481 gcctggccgc cggagggcaa cagggctgcc ttgcccggtc gctggccacc gtgctgctgt
     3541 gccgcctgcg cggtcagtgg ccgacctggt gcgtcggcgt gcgcacccag ccgccgttcg
     3601 ccgcgcacgc ctgggtggag gccgagggcg tcctcgtcgg cgaaggagcc ccggccgact
     3661 acttccagcg gttcttcacg gtggactgaa cacaggtgac cccctccccg tccccctccc
     3721 cgtatttcgc gaagcctccc ctgcgaccgc ccgcgcccgg gccggcggac cgccgcgcac
     3781 agtcggtgct ggccggggag gagtcttccg taccgccgag gcacgggccg agcggctccc
     3841 cagcggcagg cggcgcacgt cccgggacag gcgtacgcga cgagcggaca cgaccctggc
     3901 acgtcctcac ccacctgcgg ccgcaccgcc ccggcatcct cctgggcagc gcgctgtccc
     3961 tggcgggcag cctgctggcg ctcgcccagc cgctggtggc caagcagatg gtggacgccc
     4021 tggaccgcgg gcgccccgcg gccggcgcac tggtcctgct cagtgccctg gtcgtcgccg
     4081 gcgccgcgac cgccgcactg ggccagtacg tgctggagcg caccgccgag tcggtcgcct
     4141 gcacagcgcg ccggcgcctg tcggagcgcc tcctgcgtct gcgtctgccc gtgctcaacc
     4201 gcaccgagcc gggcgagctg atctcccggg tgacgtccga caccacggtg ctgcgccagg
     4261 tcgccacccg ctcgatcgcc tcagcgggca gcggcctgct ggtcgtggtg gcgacgctgg
     4321 ccctcatggc gctgctggat ccggtgctcc tgagcatcac gctggtcacc atcgcgctga
     4381 tcggcgcgac cgtcgccgcg gccgttcccc acatcgcccg ggccgcccgc caggcccagg
     4441 aggcggtcgg ccgcatgggc tccctgctcg aacgcaccct gggcgccgtg cgcaccatca
     4501 aggcgtccgg tgccgagggc cgggagacgg ccggtctgca ccaagcggcc gaggacgccc
     4561 gtcgggccgg cacccgggcc gcccggtggc aggctctgtc ggccaccacc tccaccgtcg
     4621 ccgtgcaact gtccttcctc gtcgtactgg gcgtgggcgg agcgcgcgtg gcgaccgggg
     4681 ccatcaccgt gtcgaccctc gtcgccttcc tcctctacgt cttcgccctc gccccccgcg
     4741 tggggcaact ggtcgaggcg gtcggtctgt tgcaggcggg agcggccgcc tccgcgcgta
     4801 tcggcgaggt ccactccatg gacaccgagc cggtcggtcc gcatcaggcc ccggccacca
     4861 cgccggagcc ccgccggccg gtcggggtcg tcttccaggg tgtgcgcttc tcctacggcc
     4921 ccgaggcccc gcccgtgcac gaggacgtga cgttcaccgt gccaccgaag accaccacgg
     4981 ccctggtcgg cccgtccgga gcgggcaaga ccaccgtctt ttccctgctc gaacgcttct
     5041 accaaccgga ccgtggccgc atcctcctcg acggcgagga catcgcgcgt ctcccgctgt
     5101 cccggctgcg cgccctgatc ggatacgtcg agcaggactc cccgatcctg tccggcaccc
     5161 tgcgggacaa cctcctcctc agcgctcccg atgccgatgc ggcgcaggta cgcgacgtcc
     5221 tgcgccgcac ccgcctggac tgcctcgtgg cgcgcctgcc cgacggactc gacacaccca
     5281 tcggccaccg cggcagcaca ctgtccggtg gcgaacggca gagggtggcc atcgcccgtg
     5341 ccctcctgcg ccgcccggga cttctgctgc tggacgaggc cacctcccag ctcgacgccg
     5401 ccaacgaagc cgcgctgcac gagacccttg cggacatcag ccgcaccacc acgattctgg
     5461 tgatcgccca ccgactgtcg acggtgacca cggccgacca gatcctgctg ctggaatccg
     5521 ggcgggtacg ggccgccggc acccacgcgc agttgctcgc ggccgacgcc ttctaccgtc
     5581 gcctggcagc cgcgcaacac ctcgcgtga
//
