BGC0001650: Le-pyrrolopyrazines biosynthetic gene cluster from Lysobacter enzymogenes
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Location: 1 - 26,129 nt. (total: 26,129 nt).
This entry is originally from NCBI GenBank MF495862.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001650
Short description Le-pyrrolopyrazines biosynthetic gene cluster from Lysobacter enzymogenes
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MF495862.1
via
Compounds
  • Le-pyrrolopyrazines
Species Lysobacter enzymogenes [taxonomy]
References
Chemical products information
Le-pyrrolopyrazines Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATD51275.1
 1 - 648 (-) two-component system response regulator
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    • ATD51276.1
    		 1048 - 1875 (+) PEP phosphonomutase
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      • ATD51277.1
      		 2031 - 2429 (-) alpha/beta hydrolase
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        • ATD51278.1
        		 2482 - 12507 (+) nonribosomal peptide synthase
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          • ATD51279.1
          		 12562 - 17727 (+) nonribosomal peptide synthase
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            • ATD51280.1
            		 17737 - 22404 (+) nonribosomal peptide synthase
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              • ATD51281.1
              		 22443 - 23390 (-) LysR family transcriptional regulator
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                • ATD51282.1
                		 23456 - 24073 (+) amino acid transporter
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                  • ATD51283.1
                  		 24089 - 24691 (-) phosphodiesterase
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                    • ATD51284.1
                    		 24815 - 25192 (+) MarR family transcriptional regulator
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                      • ATD51285.1
                      		 25449 - 26129 (+) DoxX family protein
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                        Biosynthesis information

                        Biosynthetic modules

                        Name
                        Unk01
                        Type
                        nrps-type1
                        Genes
                        ATD51279.1
                        Substrates
                        proline (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk02
                        Type
                        nrps-type1
                        Genes
                        ATD51279.1
                        Substrates
                        valine, leucine, isoleucine (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk03
                        Type
                        nrps-type1
                        Genes
                        ATD51280.1
                        Substrates
                        proline (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Annotation changelog

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Added NRP substrate specificities
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2018-08-06
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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