BGC0001657: lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5
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Location: 1 - 71,777 nt. (total: 71,777 nt).
This entry is originally from NCBI GenBank LC128664.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001657
Short description lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LC128664.1
via
Compounds
  • lysocin
Species Lysobacter sp. RH2180-5 [taxonomy]
References
Chemical products information
lysocin Evidence:
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C75H116N20O20
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAV56268.1
 1564 - 3240 (+) hypothetical protein
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    • BAV56269.1
    		 4160 - 5920 (+) hypothetical protein
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      • BAV56270.1
      • lesA
      		 5995 - 33765 (+)
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        • BAV56271.1
        • lesB
        		 33746 - 53263 (+)
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          • BAV56272.1
          		 53328 - 53546 (+) hypothetical protein
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            • BAV56273.1
            		 53843 - 56023 (-) hypothetical protein
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              • BAV56274.1
              		 56547 - 57773 (-) hypothetical protein
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                • BAV56275.1
                		 57818 - 58186 (-) hypothetical protein
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                  • BAV56276.1
                  		 58218 - 58721 (+) hypothetical protein
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                    • BAV56277.1
                    		 59070 - 59840 (+) hypothetical protein
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                      • BAV56278.1
                      		 60119 - 61045 (+) hypothetical protein
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                        • BAV56279.1
                        		 61137 - 61691 (+) hypothetical protein
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                          • BAV56280.1
                          		 61818 - 62351 (-) hypothetical protein
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                            • BAV56281.1
                            		 62566 - 63795 (+) hypothetical protein
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                              • BAV56282.1
                              		 63987 - 64286 (+) hypothetical protein
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                                • BAV56283.1
                                		 64376 - 65392 (+) hypothetical protein
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                                  • BAV56284.1
                                  		 65515 - 66771 (-) hypothetical protein
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                                    • BAV56285.1
                                    		 66920 - 67288 (+) hypothetical protein
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                                      • BAV56286.1
                                      		 67462 - 67842 (+) hypothetical protein
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                                        • BAV56287.1
                                        		 67839 - 69437 (+) hypothetical protein
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                                          • BAV56288.1
                                          		 69543 - 71744 (+) hypothetical protein
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                                            Biosynthesis information

                                            Biosynthetic modules

                                            Name
                                            Unk01
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            threonine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk02
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            arginine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk03
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            serine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk04
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            glycine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk05
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            phenylalanine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk06
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            leucine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk07
                                            Type
                                            nrps-type1
                                            Genes
                                            lesA
                                            Substrates
                                            arginine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk08
                                            Type
                                            nrps-type1
                                            Genes
                                            lesB
                                            Substrates
                                            glutamic acid (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk09
                                            Type
                                            nrps-type1
                                            Genes
                                            lesB
                                            Substrates
                                            glutamine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk10
                                            Type
                                            nrps-type1
                                            Genes
                                            lesB
                                            Substrates
                                            tryptophan (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk11
                                            Type
                                            nrps-type1
                                            Genes
                                            lesB
                                            Substrates
                                            valine, isoleucine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Name
                                            Unk12
                                            Type
                                            nrps-type1
                                            Genes
                                            lesB
                                            Substrates
                                            threonine (evidence: Structure-based inference, Sequence-based prediction)
                                            Integrated Monomers
                                            Domains
                                            adenylation
                                            Annotation changelog

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Added NRP substrate specificities
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2018-08-06
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            Detailed domain annotation
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