BGC0001662: mediomycin A biosynthetic gene cluster from Kitasatospora mediocidica
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Location: 6,894 - 168,396 nt. (total: 161,503 nt).
This entry is originally from NCBI GenBank MF139773.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001662
Short description mediomycin A biosynthetic gene cluster from Kitasatospora mediocidica
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MF139773.1
6894 - 168396
via
Compounds
  • mediomycin A
Species Kitasatospora mediocidica [taxonomy]
References
Chemical products information
mediomycin A Evidence:
Copy SMILES
C62H97N1O18S1
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWC08646.1
  • cleP
 6894 - 7373 (+) putative transcriptional regulator
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    • AWC08647.1
    • cleO
    		 7414 - 8199 (-) putative 4-guanidinobutyramide hydrolase
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      • AWC08648.1
      • cleN
      		 8465 - 9232 (+) putative type II TE
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        • AWC08649.1
        • cleM
        		 9320 - 12211 (+) putative LuxR-family transcriptional regulator
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          • AWC08650.1
          • cleL
          		 12250 - 12879 (-) putative two-component system response regulator
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            • AWC08651.1
            • cleK
            		 12872 - 14125 (-) putative histidine kinase
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              • AWC08652.1
              • cleJ
              		 14293 - 14826 (+) hypothetical protein
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                • AWC08653.1
                • cleI
                		 14901 - 15395 (+) putative membrane protein
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                  • AWC08654.1
                  • cleH
                  		 15392 - 16948 (+) putative membrane protein
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                    • AWC08655.1
                    • cle1
                    		 17236 - 41595 (+) polyketide synthase type I
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                      • AWC08656.1
                      • cle2
                      		 41602 - 51735 (+) polyketide synthase type I
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                        • AWC08657.1
                        • cle3
                        		 51761 - 76960 (+) polyketide synthase type I
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                          • AWC08658.1
                          • cle4
                          		 77088 - 82043 (+) polyketide synthase type I
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                            • AWC08659.1
                            • cle5
                            		 82267 - 97758 (+) polyketide synthase type I
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                              • AWC08660.1
                              • cle6
                              		 97816 - 119211 (+) polyketide synthase type I
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                                • AWC08661.1
                                • cle7
                                		 119264 - 128902 (+) polyketide synthase type I
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                                  • AWC08662.1
                                  • cle8
                                  		 128958 - 146066 (+) polyketide synthase type I
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                                    • AWC08663.1
                                    • cle9
                                    		 146148 - 157649 (+) polyketide synthase type I
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                                      • AWC08664.1
                                      • cleG
                                      		 157808 - 158752 (-) ACP acyltransferase
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                                        • AWC08665.1
                                        • cleF
                                        		 159165 - 159836 (+) putative type II TE
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                                          • AWC08666.1
                                          • cleE
                                          		 159900 - 161306 (+) putative 4-guanidinylbutanoate:CoA ligase
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                                            • AWC08667.1
                                            • cleD
                                            		 161370 - 163031 (-) putative L-arginine monooxygenase
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                                              • AWC08668.1
                                              • cleC
                                              		 163133 - 165961 (-) putative LuxR-family transcriptional regulator
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                                                • AWC08669.1
                                                • cleB
                                                		 166554 - 167603 (+) sulfotransferase
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                                                  • AWC08670.1
                                                  • cleA
                                                  		 167763 - 168353 (+) hypothetical protein
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: 3

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-09-15
                                                    Merge in annotations from duplicated entry BGC0001932
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-09-15
                                                    Cleaned up synonym list
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2019-10-16
                                                    Migrated from v1.4
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2019-10-16
                                                    Updated compound(s) information (NPAtlas curation)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2018-08-06
                                                    Submitted
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    Detailed domain annotation
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