BGC0001666: microansamycin A biosynthetic gene cluster from Micromonospora sp. HK160111
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Location: 1 - 69,750 nt. (total: 69,750 nt).
This entry is originally from NCBI GenBank MG018799.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001666
Short description microansamycin A biosynthetic gene cluster from Micromonospora sp. HK160111
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MG018799.1
via
Compounds
  • microansamycin A
  • microansamycin B
  • microansamycin C
  • microansamycin D
  • microansamycin E
  • microansamycin F
  • microansamycin G
  • microansamycin H
  • microansamycin I
Species Micromonospora sp. HK160111 [taxonomy]
References
Chemical products information
microansamycin A Evidence: NMR [1]
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C17H21N1O5
Chemical database entries
PubCHEM
NPAtlas
microansamycin B Evidence: NMR [1]
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C17H21N1O5
Chemical database entries
NPAtlas
PubCHEM
microansamycin C Evidence: NMR [1]
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C17H19N1O5
Chemical database entries
NPAtlas
PubCHEM
microansamycin D Evidence: NMR [1]
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C17H21N1O4
Chemical database entries
PubCHEM
NPAtlas
microansamycin E Evidence: NMR [1]
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C17H21N1O5
Chemical database entries
PubCHEM
NPAtlas
microansamycin F Evidence: NMR [1]
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C17H19N1O5
Chemical database entries
NPAtlas
PubCHEM
microansamycin G Evidence: NMR [1]
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C18H23N1O6
Chemical database entries
NPAtlas
PubCHEM
microansamycin H Evidence: NMR [1]
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C17H21N1O6
Chemical database entries
PubCHEM
NPAtlas
microansamycin I Evidence: NMR [1]
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C18H23N1O3
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATY46582.1
  • mas1
 164 - 1681 (-) FAD-linked oxidase domain protein
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    • ATY46583.1
    • mas2
    		 1782 - 2618 (-) shikimate dehydrogenase
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      • ATY46584.1
      • mas3
      		 2615 - 4930 (-) LuxR family transcriptional regulator
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        • ATY46585.1
        • masN
        		 5845 - 6681 (+) kinase
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          • ATY46586.1
          • masG
          		 6637 - 7719 (-) aDHQ synthase
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            • ATY46587.1
            • mas4
            		 7959 - 22766 (+) polyketide synthase
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              • ATY46588.1
              • mas5
              		 22780 - 23703 (+) monooxygenase
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                • ATY46589.1
                • mas6
                		 24264 - 25481 (+) acyltransferase
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                  • ATY46590.1
                  • mas7
                  		 25507 - 26727 (+) cytochrome P450
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                    • ATY46591.1
                    • mas8
                    		 26673 - 26969 (+) ferredoxin
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                      • ATY46592.1
                      • mas9
                      		 27042 - 28568 (-) monooxygenase FAD-binding protein
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                        • ATY46593.1
                        • mas10
                        		 28815 - 29597 (-) amide synthase
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                          • ATY46594.1
                          • mas11
                          		 29597 - 32698 (-) polyketide synthase
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                            • ATY46595.1
                            • mas12
                            		 32736 - 38057 (-) polyketide synthase
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                              • ATY46596.1
                              • mas13
                              		 38672 - 41293 (+) SARP regulator
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                                • ATY46597.1
                                • mas14
                                		 41343 - 42266 (-) NADPH:quinone reductase
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                                  • ATY46598.1
                                  • mas15
                                  		 42368 - 43558 (-) cytochrome P450
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                                    • ATY46599.1
                                    • mas16
                                    		 43981 - 45450 (-) drug resistance transporter
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                                      • ATY46600.1
                                      • mas17
                                      		 45531 - 45938 (+) HxlR family transcriptional regulator
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                                        • ATY46601.1
                                        • masJ
                                        		 46067 - 46501 (-) aminoDHQ dehydratase
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                                          • ATY46602.1
                                          • masK
                                          		 46772 - 47938 (+) AHBA synthase
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                                            • ATY46603.1
                                            • masL
                                            		 48004 - 49074 (+) oxidoreductase
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                                              • ATY46604.1
                                              • masM
                                              		 49077 - 49742 (+) phosphatase
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                                                • ATY46605.1
                                                • masN_rename1
                                                		 49819 - 51162 (-) aDAHP synthase
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                                                  • ATY46606.1
                                                  • mas18
                                                  		 51642 - 52208 (+) type II thioesterase
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                                                    • ATY46607.1
                                                    • mas19
                                                    		 52205 - 52966 (-) putative phosphate acyltransferase
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                                                      • ATY46608.1
                                                      • mas20
                                                      		 52999 - 53592 (-) TetR family regulator
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                                                        Biosynthesis information
                                                        Annotation changelog

                                                        Entry version: next

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2024-03-19
                                                        MIBiG v4 annotathon
                                                        • (ID: EMAUK5TYS6O5PLPCDCIRFTNF)
                                                        • (ID: CVBS4CX3MGQ2Y6Q45INSO263)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 2

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2019-10-16
                                                        Migrated from v1.4
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 1

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2018-08-06
                                                        Submitted
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        Detailed domain annotation
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                                                        Modifications to original record
                                                        • renamed CDS with name masN at [49818:51162](-) to masN_rename1 to avoid duplicates