Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001667.1:
Cluster 1NRP / Polyketide155137

BGC0001667, microcystin-LR / microcystin-FR / microcystin-LA / microcystin-LAba / microcystin-LM / microcystin-LV / microcystin-LL biosynthetic gene cluster from Fischerella sp. CENA161. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: microcystin-LR
SMILES string: Copy to clipboard

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Modular Type I

Gene cluster description

Download cluster GenBank file
microcystin-LR / microcystin-FR / microcystin-LA / microcystin-LAba / microcystin-LM / microcystin-LV / microcystin-LL (BGC0001667). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank KX891213. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Heck K et al. (2018) Biosynthesis of microcystin hepatotoxins in the cyanobacterial genus Fischerella. Toxicon 141:43-50. doi: 10.1016/j.toxicon.2017.10.021. Epub 2017 Nov