BGC0001671 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001671 (Agrobacterium tumefaciens (Rhizobium radiobacter))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	hserlactone,NRPS	1	77,714	monobactam	NRPS:Type I	100%

BGC0001671 - Region 1 - NRPS,hserlactone

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Location: 1 - 77,714 nt. (total: 77,714 nt) Show pHMM detection rules used

Region on contig edge.

hserlactone: Autoind_synth
NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 77,715
Label		BGC0001671

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001671	1.01	NRP	monobactam	Agrobacterium tumefaciens
BGC0002437	0.28	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0000457	0.27	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000342	0.26	NRP	enniatin	Fusarium equiseti
BGC0000313	0.26	NRP	beauvericin	Beauveria bassiana
BGC0001873	0.25	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0002518	0.24	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001833	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0002226	0.24	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0001132	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001671	1.00	NRP	monobactam	Agrobacterium tumefaciens
BGC0000457	0.63	NRP	vicibactin	Rhizobium etli CFN 42
BGC0002437	0.62	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0002226	0.61	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0000342	0.60	NRP	enniatin	Fusarium equiseti
BGC0000313	0.60	NRP	beauvericin	Beauveria bassiana
BGC0001873	0.58	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0002518	0.58	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001833	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 2, location 25425 - 74014:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

Rhz6

AMP-binding (482..883): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAIIYGHILK
Nearest Stachelhaus code(s):: Ala DVFIYAAILK (56% 8Å match)
Stachelhaus code match:: 60% (weak)

AMP-binding (2020..2427): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIWEITADDK
Nearest Stachelhaus code(s):: Dpr DIWEVTADDK (79% 8Å match); Dab DIWELTADDK (71% 8Å match)
Stachelhaus code match:: 90% (moderate)