BGC0001674: MS-271 biosynthetic gene cluster from Streptomyces mirabilis
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Location: 391,217 - 413,806 nt. (total: 22,590 nt).
This entry is originally from NCBI GenBank FONR01000003.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
Tailoring
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001674
Short description MS-271 biosynthetic gene cluster from Streptomyces mirabilis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
FONR01000003.1
396027 - 407939
via
Compounds
  • MS-271
Species Streptomyces mirabilis [taxonomy]
References
Chemical products information
MS-271 Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SAMN02787118_103369
  • SFF02396.1
 396027 - 396701 (-) two component transcriptional regulator, LuxR family
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    • SAMN02787118_103370
    • SFF02417.1
    		 396791 - 398113 (-) poly-gamma-glutamate synthesis protein (capsule biosynthesis protein)
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      • SAMN02787118_103371
      • SFF02446.1
      		 398110 - 398841 (-) Protein-disulfide isomerase
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        • SAMN02787118_103372
        • SFF02470.1
        		 398844 - 399368 (-) Methylamine utilisation protein MauE
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          • SAMN02787118_103373
          • SFF02493.1
          		 399389 - 400258 (-) ABC-2 type transport system permease protein
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            • SAMN02787118_103374
            • SFF02515.1
            		 400255 - 401220 (-) ABC-2 type transport system ATP-binding protein
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              • SAMN02787118_103375
              • SFF02531.1
              		 401217 - 401708 (-) Transglutaminase-like superfamily protein
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                • SAMN02787118_103376
                • SFF02555.1
                		 401705 - 401968 (-) Coenzyme PQQ synthesis protein D (PqqD)
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                  • SAMN02787118_103377
                  • SFF02575.1
                  		 401965 - 403806 (-) asparagine synthase (glutamine-hydrolysing)
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                    • SAMN02787118_103378
                    • SFF02595.1
                    		 403879 - 404112 (-) hypothetical protein
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                      • SAMN02787118_103379
                      • SFF02612.1
                      		 404123 - 404875 (-) ABC-2 family transporter protein
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                        • SAMN02787118_103380
                        • SFF02632.1
                        		 404868 - 405815 (-) ABC-2 type transport system ATP-binding protein
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                          • SAMN02787118_103381
                          • SFF02653.1
                          		 405962 - 407095 (-) Signal transduction histidine kinase
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                            • SAMN02787118_103382
                            • SFF02673.1
                            		 407247 - 407939 (+) DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains
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                              • SAMN02787118_103383
                              • SFF02689.1
                              		 407890 - 408819 (+) hypothetical protein
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                                Biosynthesis information

                                No biosynthesis information available for this record.

                                Annotation changelog

                                Entry version: 4

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-10-07
                                Update chemical activity to schema version 2.11
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 3

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Updated bioactivity data
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Migrated from v1.4
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2018-08-06
                                Submitted
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                Tailoring functions
                                Tailoring enzymes detected in this region
                                Hydrolases: hydrolase
                                SAMN02787118_103377: asparagine synthase (glutamine-hydrolyzing)
                                smcogs
                                SMCOG1177: asparagine synthase (glutamine-hydrolyzing)
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