BGC0001675: murayaquinone biosynthetic gene cluster from Streptomyces griseoruber
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Location: 1 - 67,000 nt. (total: 67,000 nt).
This entry is originally from NCBI GenBank KX817190.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001675
Short description murayaquinone biosynthetic gene cluster from Streptomyces griseoruber
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KX817190.1
via
Compounds
  • murayaquinone
Species Streptomyces griseoruber [taxonomy]
References
Chemical products information
murayaquinone Evidence:
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C19H16O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQW35023.1
 2081 - 2635 (+) polyketide cyclase
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    • AQW35024.1
    		 2978 - 4252 (+) cytochrome ubiquinol oxidase subunit I
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      • AQW35025.1
      		 4265 - 5026 (+) cytochrome BD oxidase subunit II
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        • AQW35026.1
        • mrqT2
        		 5178 - 7355 (+) Transmembrane transporter
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          • AQW35027.1
          • mrqR3
          		 7422 - 9356 (-) transcriptional regulator
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            • AQW35028.1
            • mrqT1
            		 9730 - 11454 (-) Multidrug MFS transporter
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              • AQW35029.1
              • mrqR2
              		 11564 - 12097 (+) MarR family transcriptional regulator
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                • AQW35030.1
                		 12188 - 13402 (-) transposase
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                  • AQW35031.1
                  		 14050 - 15075 (-) oxidoreductase
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                    • AQW35032.1
                    		 15098 - 15889 (-) N-acetyltransferase
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                      • AQW35033.1
                      		 15925 - 16950 (-) ketoacyl-ACP synthase III
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                        • AQW35034.1
                        		 17231 - 17905 (+) hypothetical protein
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                          • AQW35035.1
                          		 17957 - 18982 (+) oxidoreductase
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                            • AQW35036.1
                            		 19017 - 20612 (-) copper oxidase
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                              • AQW35037.1
                              		 20609 - 21040 (-) hypothetical protein
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                                • AQW35038.1
                                		 21268 - 22047 (+) regulatory protein
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                                  • AQW35039.1
                                  		 22050 - 22640 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
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                                    • AQW35040.1
                                    		 22654 - 23721 (-) glucose-1-phosphate thymidylyltransferase
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                                      • AQW35041.1
                                      		 23931 - 25067 (+) glycosyltransferase
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                                        • AQW35042.1
                                        		 25177 - 26160 (+) dTDP-glucose 4,6-dehydratase
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                                          • AQW35043.1
                                          		 26157 - 27041 (+) dTDP-4-dehydrorhamnose reductase
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                                            • AQW35044.1
                                            		 27083 - 28357 (+) SAM-dependent methyltransferase
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                                              • AQW35045.1
                                              		 28418 - 29464 (+) 3-oxoacyl-ACP synthase
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                                                • AQW35046.1
                                                		 29543 - 30544 (-) beta-ketoacyl synthase III
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                                                  • AQW35047.1
                                                  		 30541 - 32271 (-) Acyl-CoA synthetase
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                                                    • AQW35048.1
                                                    		 32313 - 34349 (-) phenazine biosynthesis protein PhzE
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                                                      • AQW35049.1
                                                      		 34346 - 35074 (-) phenazine biosynthesis protein PhzD
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                                                        • AQW35050.1
                                                        		 35076 - 35858 (-) 2,3-dihydroxybenzoate-2,3-dehydrogenase
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                                                          • AQW35051.1
                                                          		 35903 - 37075 (-) phospho-2-dehydro-3-deoxyheptonate aldolase
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                                                            • AQW35052.1
                                                            		 37112 - 38692 (-) carboxylesterase
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                                                              • AQW35053.1
                                                              		 38933 - 39817 (+) acetyltransferase
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                                                                • AQW35054.1
                                                                		 39817 - 41394 (+) long-chain acyl-CoA synthetase
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                                                                  • AQW35055.1
                                                                  • mrqO8
                                                                  		 41534 - 42949 (+) bifunctional monooxygenase-dehydratase
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                                                                    • AQW35056.1
                                                                    • mrqR1
                                                                    		 43022 - 43822 (-) regulatory protein
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                                                                      • AQW35057.1
                                                                      • mrqM
                                                                      		 44096 - 44833 (+) 3-oxoacyl-ACP reductase
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                                                                        • AQW35058.1
                                                                        • mrqA
                                                                        		 44937 - 46190 (+) KS
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                                                                          • AQW35059.1
                                                                          • mrqB
                                                                          		 46187 - 47431 (+) chain length factor
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                                                                            • AQW35060.1
                                                                            • mrqC
                                                                            		 47485 - 47748 (+) acyl carrier protein
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                                                                              • AQW35061.1
                                                                              • mrqO1
                                                                              		 47745 - 48671 (+) oxidoreductase
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                                                                                • AQW35062.1
                                                                                • mrqD
                                                                                		 48802 - 49761 (+) second ring cyclase
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                                                                                  • AQW35063.1
                                                                                  • mrqE
                                                                                  		 49820 - 50773 (-) cyclase
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                                                                                    • AQW35064.1
                                                                                    • mrqF
                                                                                    		 50851 - 51639 (-) Polyketide C-9 ketoreductase
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                                                                                      • AQW35065.1
                                                                                      • mrqO2
                                                                                      		 51636 - 52154 (-) flavin reductase
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                                                                                        • AQW35066.1
                                                                                        • mrqG
                                                                                        		 52347 - 53417 (+) hypothetical protein
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                                                                                          • AQW35067.1
                                                                                          • mrqO3
                                                                                          		 53453 - 54922 (+) oxidase
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                                                                                            • AQW35068.1
                                                                                            • mrqO4
                                                                                            		 54995 - 56050 (-) oxidase
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                                                                                              • AQW35069.1
                                                                                              • mrqH
                                                                                              		 56116 - 56886 (-) ketoreductase
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                                                                                                • AQW35070.1
                                                                                                • mrqI
                                                                                                		 56883 - 57344 (-) hypothetical protein
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                                                                                                  • AQW35071.1
                                                                                                  • mrqJ
                                                                                                  		 57332 - 57865 (-) cyclase
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                                                                                                    • AQW35072.1
                                                                                                    • mrqK
                                                                                                    		 57867 - 58331 (-) hypothetical protein
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                                                                                                      • AQW35073.1
                                                                                                      • mrqO5
                                                                                                      		 58328 - 58639 (-) oxygenase
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                                                                                                        • AQW35074.1
                                                                                                        • mrqO6
                                                                                                        		 58885 - 60483 (+) FAD-binding monooxygenase
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                                                                                                          • AQW35075.1
                                                                                                          • mrqO7
                                                                                                          		 60533 - 61396 (+) NAD(P)-dependent oxidoreductase
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                                                                                                            • AQW35076.1
                                                                                                            • mrqL
                                                                                                            		 61749 - 62399 (-) hypothetical protein
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                                                                                                              • AQW35077.1
                                                                                                              		 62466 - 63977 (-) MFS transporter
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                                                                                                                • AQW35078.1
                                                                                                                		 64227 - 64910 (+) TetR family transcriptional regulator
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                                                                                                                  • AQW35079.1
                                                                                                                  		 64910 - 66124 (+) two-component sensor histidine kinase
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                                                                                                                    • AQW35080.1
                                                                                                                    		 66184 - 66864 (+) two-component response regulator
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                                                                                                                      Biosynthesis information
                                                                                                                      Annotation changelog

                                                                                                                      Entry version: 4

                                                                                                                      Date
                                                                                                                      Changes
                                                                                                                      Submitters
                                                                                                                      Reviewers
                                                                                                                      2022-10-07
                                                                                                                      Update chemical activity to schema version 2.11
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                      Entry version: 3

                                                                                                                      Date
                                                                                                                      Changes
                                                                                                                      Submitters
                                                                                                                      Reviewers
                                                                                                                      2022-09-15
                                                                                                                      Updated bioactivity data
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                      Entry version: 2

                                                                                                                      Date
                                                                                                                      Changes
                                                                                                                      Submitters
                                                                                                                      Reviewers
                                                                                                                      2019-10-16
                                                                                                                      Migrated from v1.4
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      2019-10-16
                                                                                                                      Updated compound(s) information (NPAtlas curation)
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                      Entry version: 1

                                                                                                                      Date
                                                                                                                      Changes
                                                                                                                      Submitters
                                                                                                                      Reviewers
                                                                                                                      2018-08-06
                                                                                                                      Submitted
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                      Detailed domain annotation
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