BGC0001675: murayaquinone biosynthetic gene cluster from Streptomyces griseoruber
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Location: 1 - 67,000 nt. (total: 67,000 nt).
This entry is originally from NCBI GenBank KX817190.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001675
Short description murayaquinone biosynthetic gene cluster from Streptomyces griseoruber
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KX817190.1
Compounds
  • murayaquinone
Species Streptomyces griseoruber [taxonomy]
References
Chemical products information
murayaquinone
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C19H16O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQW35023.1
 2081 - 2635 (+) polyketide cyclase
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  • AQW35024.1
 2978 - 4252 (+) cytochrome ubiquinol oxidase subunit I
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  • AQW35025.1
 4265 - 5026 (+) cytochrome BD oxidase subunit II
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  • AQW35026.1
  • mrqT2
 5178 - 7355 (+) Transmembrane transporter
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  • AQW35027.1
  • mrqR3
 7422 - 9356 (-) transcriptional regulator
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  • AQW35028.1
  • mrqT1
 9730 - 11454 (-) Multidrug MFS transporter
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  • AQW35029.1
  • mrqR2
 11564 - 12097 (+) MarR family transcriptional regulator
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  • AQW35030.1
 12188 - 13402 (-) transposase
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  • AQW35031.1
 14050 - 15075 (-) oxidoreductase
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  • AQW35032.1
 15098 - 15889 (-) N-acetyltransferase
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  • AQW35033.1
 15925 - 16950 (-) ketoacyl-ACP synthase III
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  • AQW35034.1
 17231 - 17905 (+) hypothetical protein
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  • AQW35035.1
 17957 - 18982 (+) oxidoreductase
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  • AQW35036.1
 19017 - 20612 (-) copper oxidase
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  • AQW35037.1
 20609 - 21040 (-) hypothetical protein
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  • AQW35038.1
 21268 - 22047 (+) regulatory protein
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  • AQW35039.1
 22050 - 22640 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
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  • AQW35040.1
 22654 - 23721 (-) glucose-1-phosphate thymidylyltransferase
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  • AQW35041.1
 23931 - 25067 (+) glycosyltransferase
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  • AQW35042.1
 25177 - 26160 (+) dTDP-glucose 4,6-dehydratase
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  • AQW35043.1
 26157 - 27041 (+) dTDP-4-dehydrorhamnose reductase
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  • AQW35044.1
 27083 - 28357 (+) SAM-dependent methyltransferase
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  • AQW35045.1
 28418 - 29464 (+) 3-oxoacyl-ACP synthase
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  • AQW35046.1
 29543 - 30544 (-) beta-ketoacyl synthase III
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  • AQW35047.1
 30541 - 32271 (-) Acyl-CoA synthetase
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  • AQW35048.1
 32313 - 34349 (-) phenazine biosynthesis protein PhzE
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  • AQW35049.1
 34346 - 35074 (-) phenazine biosynthesis protein PhzD
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  • AQW35050.1
 35076 - 35858 (-) 2,3-dihydroxybenzoate-2,3-dehydrogenase
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  • AQW35051.1
 35903 - 37075 (-) phospho-2-dehydro-3-deoxyheptonate aldolase
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  • AQW35052.1
 37112 - 38692 (-) carboxylesterase
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  • AQW35053.1
 38933 - 39817 (+) acetyltransferase
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  • AQW35054.1
 39817 - 41394 (+) long-chain acyl-CoA synthetase
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  • AQW35055.1
  • mrqO8
 41534 - 42949 (+) bifunctional monooxygenase-dehydratase
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  • AQW35056.1
  • mrqR1
 43022 - 43822 (-) regulatory protein
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  • AQW35057.1
  • mrqM
 44096 - 44833 (+) 3-oxoacyl-ACP reductase
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  • AQW35058.1
  • mrqA
 44937 - 46190 (+) KS
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  • AQW35059.1
  • mrqB
 46187 - 47431 (+) chain length factor
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  • AQW35060.1
  • mrqC
 47485 - 47748 (+) acyl carrier protein
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  • AQW35061.1
  • mrqO1
 47745 - 48671 (+) oxidoreductase
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  • AQW35062.1
  • mrqD
 48802 - 49761 (+) second ring cyclase
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  • AQW35063.1
  • mrqE
 49820 - 50773 (-) cyclase
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  • AQW35064.1
  • mrqF
 50851 - 51639 (-) Polyketide C-9 ketoreductase
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  • AQW35065.1
  • mrqO2
 51636 - 52154 (-) flavin reductase
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  • AQW35066.1
  • mrqG
 52347 - 53417 (+) hypothetical protein
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  • AQW35067.1
  • mrqO3
 53453 - 54922 (+) oxidase
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  • AQW35068.1
  • mrqO4
 54995 - 56050 (-) oxidase
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  • AQW35069.1
  • mrqH
 56116 - 56886 (-) ketoreductase
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  • AQW35070.1
  • mrqI
 56883 - 57344 (-) hypothetical protein
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  • AQW35071.1
  • mrqJ
 57332 - 57865 (-) cyclase
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  • AQW35072.1
  • mrqK
 57867 - 58331 (-) hypothetical protein
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  • AQW35073.1
  • mrqO5
 58328 - 58639 (-) oxygenase
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  • AQW35074.1
  • mrqO6
 58885 - 60483 (+) FAD-binding monooxygenase
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  • AQW35075.1
  • mrqO7
 60533 - 61396 (+) NAD(P)-dependent oxidoreductase
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  • AQW35076.1
  • mrqL
 61749 - 62399 (-) hypothetical protein
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  • AQW35077.1
 62466 - 63977 (-) MFS transporter
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  • AQW35078.1
 64227 - 64910 (+) TetR family transcriptional regulator
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  • AQW35079.1
 64910 - 66124 (+) two-component sensor histidine kinase
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  • AQW35080.1
 66184 - 66864 (+) two-component response regulator
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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