BGC0001679 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001679 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	12,482	N-Acetyltryptophan	NRPS:Type I	100%

BGC0001679 - Region 1 - NRPS

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Location: 1 - 12,482 nt. (total: 12,482 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 12,483
Label		BGC0001679

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001679	1.00	NRP	N-Acetyltryptophan	Aspergillus nidulans FGSC A4
BGC0002320	0.25	Terpene	conidiogenone	Penicillium rubens Wisconsin 54-1255
BGC0002610	0.25	Terpene	stellatic acid	Aspergillus stellatus
BGC0001166	0.24	NRP	HC-toxin	Alternaria jesenskae
BGC0002157	0.22	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001261	0.22	NRP	AM-toxin	Alternaria alternata
BGC0002518	0.21	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0000357	0.21	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0000900	0.21	Other	ferrichrome	Aspergillus oryzae
BGC0002286	0.21	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001679	1.00	NRP	N-Acetyltryptophan	Aspergillus nidulans FGSC A4
BGC0002320	0.59	Terpene	conidiogenone	Penicillium rubens Wisconsin 54-1255
BGC0002610	0.58	Terpene	stellatic acid	Aspergillus stellatus
BGC0001166	0.57	NRP	HC-toxin	Alternaria jesenskae
BGC0002157	0.54	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001261	0.54	NRP	AM-toxin	Alternaria alternata
BGC0002518	0.54	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0000357	0.54	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0000900	0.53	Other	ferrichrome	Aspergillus oryzae
BGC0002286	0.53	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 12482:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Trp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ANIA_10576

Search NORINE for peptide: strict or relaxed

AMP-binding (233..621): Trp

nrpys: Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVDLQGVVAK
Nearest Stachelhaus code(s):: Trp DVDLQGVVAK (88% 8Å match)
Stachelhaus code match:: 100% (strong)