LOCUS       BGC0001686             15938 bp    DNA     linear   CON 31-MAY-2013
DEFINITION  Clostridium sp. CAG:567 genomic scaffold, scf7, whole genome shotgun
            sequence.
ACCESSION   BGC0001686
VERSION     BGC0001686
KEYWORDS    .
SOURCE      Clostridium sp. CAG:567
  ORGANISM  Clostridium sp. CAG:567
            Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
            Clostridium; environmental samples.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 03:31:53
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..411)
                     /codon_start=1
                     /locus_tag="BN712_00194"
                     /note="product inferred by homology to UniProt"
                     /product="putative uncharacterized protein"
                     /protein_id="CDE97352.1"
                     /transl_table=11
                     /translation="MLEKSDKYNDIINLPHHVSEKHVRMTIEERSAQFAPFSALTGYDD
                     VIKETARETNSRIEINEEQKTILNKKLLLIKEKIHNRPKITVTYFIPDVKKDGGKYIEV
                     TENVVKIDEYDRKIILENGEEVQIEEIIEIKL"
     protocluster    1..15938
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3620:11015]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3621..11015
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..15938
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..15938
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001686"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15938
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..411)
                     /locus_tag="BN712_00194"
     gene            complement(415..1914)
                     /locus_tag="BN712_00195"
     CDS             complement(415..1914)
                     /codon_start=1
                     /locus_tag="BN712_00195"
                     /note="product inferred by homology to UniProt"
                     /product="impB/MucB/SamB family protein"
                     /protein_id="CDE97353.1"
                     /transl_table=11
                     /translation="MHNEESKIYVAIDLKSFYASVECKERGLDPITTNLVVADSSRTEK
                     TICLAVSPALKSYGIPGRARLFEVVQKVKEINVYRKRKATNRTFTGSSYSDIELKKNKN
                     LELSYIIAPPRMAYYMKYSSKIYNIYLKYFSSDDIYVYSIDEVFIDVTHYLKTYNMGAK
                     ELVTKVMQDVYKTTGITATAGIGTNLYLCKIAMDIVAKHAKPDNNGVRIAGLDEMAYRK
                     LLWSHRPLTDFWRVGKGYSKRLEEHGMYTMGDVAKMSVKNEELLYKLFGVNAELLIDHA
                     WGWENVTIESIKAYRPATNSICSGQVLHCPYNYENTKLIVKEMTELLALDLVEKGLVAN
                     QIVLEIGYDVDNLKNQAISSKYNGEITTDKYGRKVPKHAHGTINIDHQTSSSKVLTEHI
                     IKLYEQIINKQLLVRRINITVNNVVNENMVQNSNYEQINLFVDYKEVNKKREKEEAEKE
                     IQKAMINIKNKYGKNAIIKGMNLQKEGTTIERNKQIGGHKE"
     gene            complement(1989..2249)
                     /locus_tag="BN712_00196"
     CDS             complement(1989..2249)
                     /codon_start=1
                     /locus_tag="BN712_00196"
                     /note="product inferred by homology to UniProt"
                     /product="iron-sulfur cluster-binding protein rieske
                     family"
                     /protein_id="CDE97354.1"
                     /transl_table=11
                     /translation="MCAKILRPQWHPMAYEHTKVIDLKEKGGYYEVTTEKGNVITAKNV
                     VIAKHYPIINAPGYYFLKIYQSMSYAIDGKSIYAPSIKNLQ"
     gene            complement(2312..3448)
                     /locus_tag="BN712_00197"
     CDS             complement(2312..3448)
                     /codon_start=1
                     /locus_tag="BN712_00197"
                     /note="product inferred by homology to UniProt"
                     /product="peptidase S1 and S6 chymotrypsin/Hap"
                     /protein_id="CDE97355.1"
                     /transl_table=11
                     /translation="MEEYIRRKQRKDRVKKYFITTFIIILITILMALTYILYFNIETPT
                     QIIKPYEASKISQTVEKTKKENETITQMLERVTESVVGISKLKSTGNSIFLKDGTSKLG
                     LGTGIIVSENGYILTNEHVSGEKYSNCYVTLATGKSYQGNVVWSSTDLDLAIVKINAKN
                     LQYITLGNSSDVKLGQIVYAIGNPIGFEFQRTVTSGIVSATNRTIILNEDEKSSYMENL
                     IQTDATINPGNSGGPLVNESGEVIGINSVKITSAEGIGFAIPINIVKTIIQSFVTSGEF
                     EEAYLGVFAYDKNIIPYLDNNLEIDDGIYVVQVNNKSSAEMYGIKEKDILLEVDGIALE
                     KMCDLRSYIYTKKPGDEVIFKVLRNKRESNITVKLSKK"
     gene            3621..11015
                     /locus_tag="BN712_00198"
     CDS             3621..11015
                     /NRPS_PKS="Domain: Condensation_Starter (4-294). E-value:
                     8.7e-64. Score: 207.5. Matches aSDomain:
                     nrpspksdomains_BN712_00198_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (458-852). E-value: 1.5e-99.
                     Score: 325.1. Matches aSDomain:
                     nrpspksdomains_BN712_00198_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (955-1022). E-value: 9.1e-23. Score:
                     72.1. Matches aSDomain: nrpspksdomains_BN712_00198_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1037-1323). E-value:
                     7.8e-79. Score: 256.6. Matches aSDomain:
                     nrpspksdomains_BN712_00198_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1488-1876). E-value:
                     4.4e-93. Score: 303.9. Matches aSDomain:
                     nrpspksdomains_BN712_00198_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1981-2042). E-value: 1.2e-13.
                     Score: 42.9. Matches aSDomain:
                     nrpspksdomains_BN712_00198_PCP.2"
                     /NRPS_PKS="Domain: NAD_binding_4 (2091-2344). E-value:
                     2.6e-38. Score: 123.3. Matches aSDomain:
                     nrpspksdomains_BN712_00198_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     263; E-value: 9.8e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="BN712_00198"
                     /note="product inferred by homology to UniProt"
                     /product="plipastatin synthase subunit C"
                     /protein_id="CDE97356.1"
                     /sec_met_domain="Condensation (E-value: 6.7e-72, bitscore:
                     231.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-106, bitscore:
                     345.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-17, bitscore:
                     52.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.3e-39, bitscore:
                     123.3, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNLYNLTNPQKSIWLMDQVNPGTNLNNIGGPVLINDSVNVPLL
                     EKALNLYIEKNEATRLRIKLVDSSPMQYVADYSYFTIPVTKLKNEKELEDWNQKIIDTP
                     FNVFDSNLYSLSIFVLPDGRGGFNATLHHLITDAWSMSLLITEVMSNYSNLIHNNSVDY
                     VFPNYTDFIDAENNYINSEKFPKDRLFWDEYFENCPELCSISSNNINSNMIAKRKSYIL
                     NSDLFAKINDFCKLLNCSVYTFFMSIYSIYLSKLTNISEPIIGTPVLNRTNFKEKHTSG
                     MFISTVPFKAKVDSNITFSEFVKSVAITQLAIFRHQKYPYSHLLEDLKKKYNFSENLYD
                     IALSYQNARDNKENCDIDYSSGWLFSGKCTDTLQVHFYDMDNTGDLNIFYDYQLDKLSD
                     EEINTLHERIMNIVNQVLLNNEIEIKNIEIVTENEKEFFISQFNNNILDYSKEKSIIEL
                     FDEQVKLHPNAIAVSDDKNSISYIELQKRINSLSYELQKQGVKKGDVVSTFLKRSPELI
                     ISLLAIMKIGGIYLPISTSLPEERVEYILNDSNSRCCITASNCSYLKNVIFIDKINNQN
                     SQLTPVTYLPDDVIYTIYTSGSTGNPKGVQVTNKNLNNFVCSFNKYFDHKVSTQDICLA
                     STNISFDVSIWEIFFTLLNGAQLYLYDEDNISDIFHYCDVILKHNVTMLYIPPNILENV
                     YSILHESNNVKIDKILVGVEPIKNSTIQKFFSLNENMQIVNGYGPTETTICCTAFKVAK
                     KEANDNSIIPIGKPLYNLTAYVLNKDLNIVPEGIAGELFIGGDNVTKGYLNNETLTNEK
                     YIQSPFKADERLYRTGDLVKFLPDGNLLFVGRDDKQVKVRGHRIEINEIENTISMYPNI
                     QKCIINLRNNNQVIVAFIVASTNISTKDLKQFLLTKLPAYSVPNFIIQLDSFPTTANGK
                     IDKKQLNNIEINFSMNYVAPQNELQQQLVDIWSEILQVNNIGIEDSFFEIGGDSLSSIR
                     LVSEIYNKFGIKLTVNNIFENDTIEDLAVYMQAQNASLVENIEKAKISDSYPLTSAQKG
                     IYYAVSLEENPSITYNTPGGIFLTGNLNIKKLEDCINTLIKKHVALRTYFTMQNNELVQ
                     KIDDNINFSLKIENGNINDVDTIFAKFVQPFDLSKAPLFRIKLIEFDKTHYLLLVDFHH
                     IICDGTSIGIFTAELVNLYNGNSIKENNFDYIDYAIFENKLKSSEKYNQMKQFWKSKFD
                     GELPVLNMPTNFARPANRSFEGDEVLLNITNADEIYTLCKSLHTTPYFFLLSVYYILLS
                     KYTSQEDIIVGTAVAGRDDANFANILGMFVNTLALREKIDSNLSFNEFLNIVTQTGLAC
                     LENQTYPFDELVKELNLNRNTNRAPLFDTMFVYQNEESALIDFSGVETKLYTPCSKVSK
                     FDFSLDLTPKSNVISARLEYATSLFTKDFMTQFLNHYISLIKLILNDIHVTIKEISLLN
                     KDEKLEIEKTYNSSILPYDENVKLVELFENEAEKNPNNIAIRFNGSSITYEELNKKANQ
                     IANFLISKNVKRNQIVGILLPRTPDLLFAMLGILKSGAGYMLIDTSLPYDRISFMLENA
                     HSNYLITNKDSKNIDGVEKLYLDELPLENYSAQNVNAYSDNEDSFAVIYTSGSTGTPKG
                     VELKRKGVINMLSNYKAFLYTDTCTNFLSMSSVAFDMFIVENFVPLLSGKTVILTNEEE
                     QKIPLYTNTLIEQEHVNFILTTPSRMDLLLSVGSNWNTIKVIQLGGEVFPSNLYDKIKA
                     QTSNAHIFNGYGPSEITACCTSKEVYNSNDITIGKPFANTQLWICNKDLNICPIGVEGE
                     ICVAGLGVGKGYINNPDLTNKSFVPNPFGDGIMYKTGDIGKYKSNGDIEFIGRRDSQIK
                     IRGLRVELSEIENQFLKIPEITNICIIYKKETVPYLAAFFTSSGEIETSVIRKQLSETL
                     PLYMVPKYIIKLDKLPITLNGKIDKKQLENYSISQVETRTYVAPRNETEKLCCNIWESL
                     LNCQIGIDDDIFEMGADSLLAIKFKTELLAYNINITYSDIFKYHTVRELVSTHGEYDIE
                     LLDNKDFVECHNALEKNVASNFATSLSNLQSSSYNNILLLGANGFVGSHILYSFIKNDT
                     GNAYCIVRDKDRKEGKTRFLETLHFYFGNELDHYLNNRIFVINSSILDENFGMSEKDYL
                     ELLNSIDVIINSAAIVKHYGNEEKFKKINVGLTEKLIDICTKFNKRLLHVSSLSVSGNL
                     SLDGSYADRIHEVTENMNFSEHNLYIGQILDNEYIKSKFLSEKLILENISKNGLQAQIL
                     RLGNITNRYSDGAFQINYQENAFLERMLTFIELGYVPNNLLDMYIEFTPVDVCGNAIIK
                     ILQNYVPDFSVYHLYNDNHVYMNEFLKILQEENINIVSVSPEEFGKKITDLSKNAKSAN
                     ILSGIINDLGPDKQLEYKSNINILSDFTKAFLYHINFKWPKIDESYLKKYINYLRKYLA
                     "
     aSDomain        3633..4502
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_Condensation_Starter
                     .1"
                     /domain_subtype="Condensation_Starter"
                     /evalue="8.70E-64"
                     /label="BN712_00198_Condensation_Starter.1"
                     /locus_tag="BN712_00198"
                     /protein_end="294"
                     /protein_start="4"
                     /score="207.5"
                     /tool="antismash"
                     /translation="LYNLTNPQKSIWLMDQVNPGTNLNNIGGPVLINDSVNVPLLEKAL
                     NLYIEKNEATRLRIKLVDSSPMQYVADYSYFTIPVTKLKNEKELEDWNQKIIDTPFNVF
                     DSNLYSLSIFVLPDGRGGFNATLHHLITDAWSMSLLITEVMSNYSNLIHNNSVDYVFPN
                     YTDFIDAENNYINSEKFPKDRLFWDEYFENCPELCSISSNNINSNMIAKRKSYILNSDL
                     FAKINDFCKLLNCSVYTFFMSIYSIYLSKLTNISEPIIGTPVLNRTNFKEKHTSGMFIS
                     TVPFKAKVD"
     aSModule        3633..6686
                     /complete
                     /domains="nrpspksdomains_BN712_00198_Condensation_Starter.1
                     "
                     /domains="nrpspksdomains_BN712_00198_AMP-binding.1"
                     /domains="nrpspksdomains_BN712_00198_PCP.1"
                     /locus_tags="BN712_00198"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3636..3671
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0001"
                     /evalue="4.90E-01"
                     /label="C1_starter_004-017"
                     /locus_tag="BN712_00198"
                     /protein_end="17"
                     /protein_start="5"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YNLTNPQKSIWL"
     CDS_motif       3699..3809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0002"
                     /evalue="1.20E-03"
                     /label="C2_starter_024-063"
                     /locus_tag="BN712_00198"
                     /protein_end="63"
                     /protein_start="26"
                     /score="11.5"
                     /tool="antismash"
                     /translation="LNNIGGPVLINDSVNVPLLEKALNLYIEKNEATRLRI"
     CDS_motif       4011..4076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0003"
                     /evalue="1.30E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="BN712_00198"
                     /protein_end="152"
                     /protein_start="130"
                     /score="24.2"
                     /tool="antismash"
                     /translation="LHHLITDAWSMSLLITEVMSNY"
     CDS_motif       4407..4487
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0004"
                     /evalue="1.30E-07"
                     /label="C5_starter_265-294"
                     /locus_tag="BN712_00198"
                     /protein_end="289"
                     /protein_start="262"
                     /score="24.1"
                     /tool="antismash"
                     /translation="IIGTPVLNRTNFKEKHTSGMFISTVPF"
     CDS_motif       4548..4613
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0005"
                     /evalue="7.90E-05"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="BN712_00198"
                     /protein_end="331"
                     /protein_start="309"
                     /score="15.3"
                     /tool="antismash"
                     /translation="QLAIFRHQKYPYSHLLEDLKKK"
     aSDomain        4995..6176
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_AMP-binding.1"
                     /evalue="1.50E-99"
                     /label="BN712_00198_AMP-binding.1"
                     /locus_tag="BN712_00198"
                     /protein_end="852"
                     /protein_start="458"
                     /score="325.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FDEQVKLHPNAIAVSDDKNSISYIELQKRINSLSYELQKQGVKKG
                     DVVSTFLKRSPELIISLLAIMKIGGIYLPISTSLPEERVEYILNDSNSRCCITASNCSY
                     LKNVIFIDKINNQNSQLTPVTYLPDDVIYTIYTSGSTGNPKGVQVTNKNLNNFVCSFNK
                     YFDHKVSTQDICLASTNISFDVSIWEIFFTLLNGAQLYLYDEDNISDIFHYCDVILKHN
                     VTMLYIPPNILENVYSILHESNNVKIDKILVGVEPIKNSTIQKFFSLNENMQIVNGYGP
                     TETTICCTAFKVAKKEANDNSIIPIGKPLYNLTAYVLNKDLNIVPEGIAGELFIGGDNV
                     TKGYLNNETLTNEKYIQSPFKADERLYRTGDLVKFLPDGNLLFVGRDDKQVKVR"
     CDS_motif       5181..5219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0006"
                     /evalue="6.60E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="BN712_00198"
                     /protein_end="533"
                     /protein_start="520"
                     /score="10.2"
                     /tool="antismash"
                     /translation="LAIMKIGGIYLPI"
     CDS_motif       5391..5444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0007"
                     /evalue="2.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="BN712_00198"
                     /protein_end="608"
                     /protein_start="590"
                     /score="23.2"
                     /tool="antismash"
                     /translation="YTIYTSGSTGNPKGVQVT"
     CDS_motif       5829..5858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0008"
                     /evalue="1.90E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="BN712_00198"
                     /protein_end="746"
                     /protein_start="736"
                     /score="7.9"
                     /tool="antismash"
                     /translation="YGPTETTICC"
     CDS_motif       5970..6056
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0009"
                     /evalue="2.70E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="BN712_00198"
                     /protein_end="812"
                     /protein_start="783"
                     /score="32.5"
                     /tool="antismash"
                     /translation="PEGIAGELFIGGDNVTKGYLNNETLTNEK"
     CDS_motif       6141..6206
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0010"
                     /evalue="4.60E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="BN712_00198"
                     /protein_end="862"
                     /protein_start="840"
                     /score="28.5"
                     /tool="antismash"
                     /translation="FVGRDDKQVKVRGHRIEINEIE"
     aSDomain        6486..6686
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_PCP.1"
                     /evalue="9.10E-23"
                     /label="BN712_00198_PCP.1"
                     /locus_tag="BN712_00198"
                     /protein_end="1022"
                     /protein_start="955"
                     /score="72.1"
                     /tool="antismash"
                     /translation="QQLVDIWSEILQVNNIGIEDSFFEIGGDSLSSIRLVSEIYNKFGI
                     KLTVNNIFENDTIEDLAVYMQA"
     aSDomain        6732..7589
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="7.80E-79"
                     /label="BN712_00198_Condensation_LCL.1"
                     /locus_tag="BN712_00198"
                     /protein_end="1323"
                     /protein_start="1037"
                     /score="256.6"
                     /tool="antismash"
                     /translation="DSYPLTSAQKGIYYAVSLEENPSITYNTPGGIFLTGNLNIKKLED
                     CINTLIKKHVALRTYFTMQNNELVQKIDDNINFSLKIENGNINDVDTIFAKFVQPFDLS
                     KAPLFRIKLIEFDKTHYLLLVDFHHIICDGTSIGIFTAELVNLYNGNSIKENNFDYIDY
                     AIFENKLKSSEKYNQMKQFWKSKFDGELPVLNMPTNFARPANRSFEGDEVLLNITNADE
                     IYTLCKSLHTTPYFFLLSVYYILLSKYTSQEDIIVGTAVAGRDDANFANILGMFVNTLA
                     LREKI"
     aSModule        6732..10652
                     /complete
                     /domains="nrpspksdomains_BN712_00198_Condensation_LCL.1"
                     /domains="nrpspksdomains_BN712_00198_AMP-binding.2"
                     /domains="nrpspksdomains_BN712_00198_PCP.2"
                     /domains="nrpspksdomains_BN712_00198_NAD_binding_4.1"
                     /locus_tags="BN712_00198"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6738..6776
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0011"
                     /evalue="2.50E-01"
                     /label="C1_starter_004-017"
                     /locus_tag="BN712_00198"
                     /protein_end="1052"
                     /protein_start="1039"
                     /score="4.9"
                     /tool="antismash"
                     /translation="YPLTSAQKGIYYA"
     CDS_motif       6804..6914
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0012"
                     /evalue="1.20E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="BN712_00198"
                     /protein_end="1098"
                     /protein_start="1061"
                     /score="27.3"
                     /tool="antismash"
                     /translation="TYNTPGGIFLTGNLNIKKLEDCINTLIKKHVALRTYF"
     CDS_motif       7110..7175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0013"
                     /evalue="9.60E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="BN712_00198"
                     /protein_end="1185"
                     /protein_start="1163"
                     /score="27.8"
                     /tool="antismash"
                     /translation="FHHIICDGTSIGIFTAELVNLY"
     CDS_motif       7491..7580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0014"
                     /evalue="2.60E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="BN712_00198"
                     /protein_end="1320"
                     /protein_start="1290"
                     /score="39.1"
                     /tool="antismash"
                     /translation="DIIVGTAVAGRDDANFANILGMFVNTLALR"
     CDS_motif       7641..7748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0015"
                     /evalue="2.20E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BN712_00198"
                     /protein_end="1376"
                     /protein_start="1340"
                     /score="45.7"
                     /tool="antismash"
                     /translation="LACLENQTYPFDELVKELNLNRNTNRAPLFDTMFVY"
     aSDomain        8085..9248
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_AMP-binding.2"
                     /evalue="4.40E-93"
                     /label="BN712_00198_AMP-binding.2"
                     /locus_tag="BN712_00198"
                     /protein_end="1876"
                     /protein_start="1488"
                     /score="303.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FENEAEKNPNNIAIRFNGSSITYEELNKKANQIANFLISKNVKRN
                     QIVGILLPRTPDLLFAMLGILKSGAGYMLIDTSLPYDRISFMLENAHSNYLITNKDSKN
                     IDGVEKLYLDELPLENYSAQNVNAYSDNEDSFAVIYTSGSTGTPKGVELKRKGVINMLS
                     NYKAFLYTDTCTNFLSMSSVAFDMFIVENFVPLLSGKTVILTNEEEQKIPLYTNTLIEQ
                     EHVNFILTTPSRMDLLLSVGSNWNTIKVIQLGGEVFPSNLYDKIKAQTSNAHIFNGYGP
                     SEITACCTSKEVYNSNDITIGKPFANTQLWICNKDLNICPIGVEGEICVAGLGVGKGYI
                     NNPDLTNKSFVPNPFGDGIMYKTGDIGKYKSNGDIEFIGRRDSQIKIR"
     CDS_motif       8271..8312
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0016"
                     /evalue="4.90E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="BN712_00198"
                     /protein_end="1564"
                     /protein_start="1550"
                     /score="7.6"
                     /tool="antismash"
                     /translation="LGILKSGAGYMLID"
     CDS_motif       8496..8543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0017"
                     /evalue="1.20E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="BN712_00198"
                     /protein_end="1641"
                     /protein_start="1625"
                     /score="21.1"
                     /tool="antismash"
                     /translation="VIYTSGSTGTPKGVEL"
     CDS_motif       8919..8948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0018"
                     /evalue="1.60E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="BN712_00198"
                     /protein_end="1776"
                     /protein_start="1766"
                     /score="2.5"
                     /tool="antismash"
                     /translation="YGPSEITACC"
     CDS_motif       9045..9134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0019"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="BN712_00198"
                     /protein_end="1838"
                     /protein_start="1808"
                     /score="39.4"
                     /tool="antismash"
                     /translation="PIGVEGEICVAGLGVGKGYINNPDLTNKSF"
     CDS_motif       9213..9278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN712_00198_0020"
                     /evalue="9.90E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BN712_00198"
                     /protein_end="1886"
                     /protein_start="1864"
                     /score="30.6"
                     /tool="antismash"
                     /translation="FIGRRDSQIKIRGLRVELSEIE"
     aSDomain        9564..9746
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_PCP.2"
                     /evalue="1.20E-13"
                     /label="BN712_00198_PCP.2"
                     /locus_tag="BN712_00198"
                     /protein_end="2042"
                     /protein_start="1981"
                     /score="42.9"
                     /tool="antismash"
                     /translation="EKLCCNIWESLLNCQIGIDDDIFEMGADSLLAIKFKTELLAYNIN
                     ITYSDIFKYHTVRELV"
     aSDomain        9894..10652
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN712_00198_NAD_binding_4.1"
                     /evalue="2.60E-38"
                     /label="BN712_00198_NAD_binding_4.1"
                     /locus_tag="BN712_00198"
                     /protein_end="2344"
                     /protein_start="2091"
                     /score="123.3"
                     /tool="antismash"
                     /translation="GANGFVGSHILYSFIKNDTGNAYCIVRDKDRKEGKTRFLETLHFY
                     FGNELDHYLNNRIFVINSSILDENFGMSEKDYLELLNSIDVIINSAAIVKHYGNEEKFK
                     KINVGLTEKLIDICTKFNKRLLHVSSLSVSGNLSLDGSYADRIHEVTENMNFSEHNLYI
                     GQILDNEYIKSKFLSEKLILENISKNGLQAQILRLGNITNRYSDGAFQINYQENAFLER
                     MLTFIELGYVPNNLLDMYIEFTPVDVCGNAI"
     gene            11080..12885
                     /locus_tag="BN712_00199"
     CDS             11080..12885
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 132; E-value: 6e-40)"
                     /gene_kind="regulatory"
                     /locus_tag="BN712_00199"
                     /note="product inferred by homology to UniProt"
                     /product="integral membrane sensor signal transduction
                     histidine kinase"
                     /protein_id="CDE97357.1"
                     /transl_table=11
                     /translation="MKNLNYLVILIISAIIMTVLLLVIKKTQKTKKQIYYSFITLVGLM
                     LVWTISLIMQILCQNTSIPPVYFEYTAAFGGCFLSVAFFFFALIMSKTKIKFKLWYLLL
                     FVIPILSCICLWTNDFHHLFYAKYSINLNDTVKGPFIMVHSVYTFALLILAIFILFKYS
                     FKTSGFFSKQSLLIVLGALIPLVINLLGMLGIPMTVYLTPICFALTILFFALAVFRFGL
                     MKVTPIALQTIADKISDGYLVLDENGIITDFNATVLKMFKLDGNYIRGKNLFDIVNTGN
                     YFSVNTEKLKNCIDIAKDTPDTFHFEKKLVNEDKYFNIEINSIQNDKTFLGILVLFKDT
                     TQHMLDMQTIKNNQNMLMERERLASLGQLIGGIAHNLKTPIMSISGAAEGLTDLVKEYE
                     ASVGDPEVTVQDHHDIAKDMKDWIDKIRSYTEYMSDVITAVKGQAVTMSEEQAVSFTLD
                     ELVKRVNILMKHELKNALVELNVCMKTDERTVLKGNINSLVQVINNMVSNAIQSYDGKP
                     DNKIDLILSKQNNNVVISVKDYGNGLPDEVQKKLFKEMITTKGKNGTGLGLFMSYSTIR
                     AHFNGNITFETEKGKGTTFNVILPL"
     gene            13025..14077
                     /locus_tag="BN712_00200"
     CDS             13025..14077
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 80.8; E-value: 1.8e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="BN712_00200"
                     /note="product inferred by homology to UniProt"
                     /product="response regulator receiver modulated metal
                     dependent phosphohydrolase"
                     /protein_id="CDE97358.1"
                     /transl_table=11
                     /translation="MRKNMQSANDKGYRIIAVDDEEGIVDSLSIFLKRSGYDFTGVTDP
                     MEAIEKVKNEHFDLMILDFIMTPIHGDQVVEEIRKFNKELYILLLTGHKDLAPPLETIR
                     KLDIQGYCEKSDKFDQLLLLIESGIKSIEQMNEIKRINEELSSTYEKLERAYLDSIQTL
                     RYTVEAKDPYTRGHSDRVSKYSVLIGKYLGLSDTDLKTLEVGGLFHDIGKIGIPDSILL
                     KESKLTDDEYSQIKNHPSIGAHILCNAEVFQDIIPIVKHHHERFDGTGYPGKLKGNDIP
                     YLARIAAVADTFDAMTSRRTYRDPLSLDVVKAEFERCSGTQFDPEIAKVFLDILNNHYD
                     EVNEIQEQFK"
     gene            14089..15201
                     /locus_tag="BN712_00201"
     CDS             14089..15201
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BN712_00201"
                     /note="product inferred by homology to UniProt"
                     /product="putative uncharacterized protein"
                     /protein_id="CDE97359.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.2e-13,
                     bitscore: 40.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKVLVLSCSTGGGHNSAASAITEELRNKGVQVDFKEYLDLINYK
                     IANVVNKLYISSTKGNGAVFKRVYKLGELYEKTKITSPVYGVNKLHRRKLYNYIVENKY
                     DYVVVTHLFPAEVLTAIKKQHDIHFIAVATDYKSIPFWPETNPDYFIIPHKDLIEDFTK
                     KGISHEKLIPFGIPVSTNFSKDLDKSKIFAELNLDKNKKYILVMTGSMGFGNVTGIIDV
                     LQNEISETILVACGNNKKVYEDISNNYNSNKVIPIGFTPQIYKYMTISELLLTKPGGLT
                     TTEAATINIPIIHTMPIPGCETYNAEFFGSHGMSISCKNTNDIKNAVISLLTDKNKMEN
                     IIKAQKQNIDKNACSKICEFIIDEIRKYSK"
     gene            15198..15938
                     /locus_tag="BN712_00202"
     CDS             15198..15938
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 82.6; E-value: 4.4e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BN712_00202"
                     /note="product inferred by homology to UniProt"
                     /product="putative uncharacterized protein"
                     /protein_id="CDE97360.1"
                     /transl_table=11
                     /translation="MKENLQSNVNNENEDIIKMWEPLKFDIGLNYKYVKNNIFFKLISN
                     LFYYIIVAPIIFLISNIIFGLKIEGKENLKNIKTGAISVSNHVQYIDCAMLGLAWFPRR
                     IYYTAKTDGFKMPVVRHLVRLLYAIPIPEKISCKENFYKAIDDLLAKNKVVHFYPEASL
                     WPYYNKLRNFKNGAFKIASKNNVPIIPFVFSFRKPTGILKLFKSKPCLILSVLPPVYPK
                     QNLAFNERYLDLKENVYKKMSEKI"
ORIGIN
        1 ttataattta atctcaataa tctcttcaat ttgaacttct tccccatttt ctagtataat
       61 ttttctatca tattcatcta tttttactac attttctgtt acttcaatat attttccgcc
      121 atctttttta acatctggta taaaatatgt aactgtaatt tttggcctat tatgtatttt
      181 ttcttttatt aaaagcaatt ttttatttaa aattgtcttt tgttcttcat ttatttctat
      241 tctactatta gtttccctgg ctgtttcttt tattacatca tcatatccag ttaatgctga
      301 aaaaggtgca aattgtgcag atctttcttc tattgtcatt cttacatgtt tttcagatac
      361 atgatgtggt aaatttatta tatcgttata tttatcactt ttttctaaca ccttttattc
      421 tttatgacct cctatttgct tatttctttc aatagttgtg ccctcttttt gcaaattcat
      481 tccttttatt atagcatttt ttccatattt gttttttata ttaatcattg ctttttgtat
      541 ttctttttct gcttcttctt tttctctttt tttattgact tctttatagt ctacaaataa
      601 attaatttgc tcataattgc tattttgcac catattttca tttaccacat tattaactgt
      661 aatattgatt cttcttacta aaagttgttt attaataatt tgttcatata attttattat
      721 atgttctgta agaactttgc tagaagatgt ttgatggtct atatttattg ttccatgtgc
      781 atgttttggt acttttcttc catatttatc agttgttatt tctccgttat atttgctact
      841 aattgcttga tttttcaagt tatctacatc atacccaatt tctaatacaa tttgatttgc
      901 aactagccct ttttctacta gatctagtgc aagtagttca gtcatttcct ttacaattag
      961 ttttgtattt tcgtaattgt atggacaatg taaaacttgt ccagagcata tactatttgt
     1021 agctggtcta tatgccttaa tactctcaat tgttacattt tcccatcccc aagcatggtc
     1081 aattagtagc tctgcattta cgccaaataa tttatatagt agttcttcat ttttaactga
     1141 cattttagct acatcaccca ttgtgtacat tccatgctct tctagtcttt ttgaatagcc
     1201 tttaccaact ctccaaaaat ctgttaaagg tctgtggctc caaagtaatt ttctatatgc
     1261 catttcatca agaccagcta ttcttacacc attgttatct ggttttgcat gctttgctac
     1321 aatgtccatt gctattttgc aaagatataa attagttcca attcctgcgg ttgctgttat
     1381 tcctgttgtt ttataaacat cttgcattac ttttgttact aactcttttg ctcccatatt
     1441 atatgttttt aggtaatgtg taacatctat aaatacctca tctattgaat atacatatat
     1501 atcatcagat gaaaaatatt ttaaatatat attataaatt tttgaactgt atttcatata
     1561 ataagccatt cttggtggtg ctattatata acttaattct aaatttttat ttttctttaa
     1621 ttcaatatca ctatatgatg atcctgtaaa tgttctattt gttgcctttc tttttctgta
     1681 tacatttatc tcttttactt tttgaacaac ttcaaaaagc cttgctctac ctggtattcc
     1741 ataggatttt agtgctgggc ttacagcaag gcaaattgtt ttttctgttc tactactatc
     1801 agcaactact aagtttgtag taattgggtc tagtcctctt tctttacatt caacagaggc
     1861 ataaaagctt tttaaatcta ttgctacata tattttactt tcttcattat gcatagcaat
     1921 cttcctttca tcactctgtt ttattatatc aacttatttg cgttttgtaa acgcttgttt
     1981 gtaagtaatt attgtaaatt tttaatactt ggtgcatata ttgattttcc atcaattgca
     2041 taagacattg attgatatat ttttaaaaag taataacctg gtgcatttat aattgggtaa
     2101 tgttttgcaa ttactacatt ttttgctgta ataacatttc ctttttctgt tgttacttca
     2161 taatagccac ctttttcttt taaatctata acttttgtgt gttcatatgc cattgggtgc
     2221 cattggggac ggagaatttt ggcacacata ataatatttt acatcttttt aatttaaaaa
     2281 tgtgccaaaa ttctccgtcc ccaatggcac attatttttt cgatagttta actgtaatgt
     2341 tactttctct tttattacgt aaaaccttaa atataacctc atctccaggc tttttagtat
     2401 aaatgtaact tctcaaatca cacattttct caagtgcgat tccatcaact tccaataata
     2461 tatctttttc ttttattcca tacatttctg cagatgattt gttattaact tgtaccacat
     2521 aaattccgtc atcaatttcc aaattattat ctaaataagg tattatattt ttatcataag
     2581 caaatacacc caagtatgct tcttcaaact ctcctgatgt tacaaaactt tgaataattg
     2641 tttttactat atttattgga attgcaaacc ctataccttc tgcagatgta atttttacac
     2701 tatttattcc tataacttct ccactttcgt ttacaagtgg tcctccacta tttccggggt
     2761 ttattgtagc atctgtttgt attaaatttt ccatatatga agatttttcg tcttcattta
     2821 aaattattgt tctatttgtt gcacttacaa ttccagatgt tacagttctt tgaaattcaa
     2881 acccaattgg atttccaatt gcatatacaa tttgtcctaa tttcacatca gatgaatttc
     2941 ctaaagttat atattgcaag ttttttgcat ttatttttac aattgccaaa tctaaatctg
     3001 tgcttgacca tacaacattt ccctgataac tttttcctgt tgcaagtgtt acataacaat
     3061 tactatattt ttcccctgaa acatgctcat ttgttaatat atagccattt tcagaaacta
     3121 taattcctgt tcctaatccc aattttgatg ttccatcttt taaaaatatt gaatttcctg
     3181 tgctttttaa tttggaaatt ccaactacac tttcagtaac tctctcaagc atttgtgtaa
     3241 tagtttcatt ttctttttta gttttttcaa cagtttgcga tattttactt gcctcataag
     3301 gtttaattat ttgtgttggt gtttcaatat taaaatacaa aatgtatgta agtgccataa
     3361 gtatagttat taaaataatt ataaaagttg ttataaagta tttttttacc ctatcttttc
     3421 tttgctttct tcttatatat tcttccattg tgccctcctt ttgctaaaat tatgaacaca
     3481 aaaaataatt ttaatcataa ttaaaataaa ttcccatatt tccccatttt tttactatat
     3541 tttcattgat ttttagcatt atttcatata taatttacct agaatttttg tgaaaacact
     3601 aataaagggg atttttcatt atggagaaaa atttatataa tttaaccaac ccacaaaagt
     3661 caatttggct tatggatcaa gtaaatcctg gcacaaattt aaataacatt ggtggacctg
     3721 ttttaattaa tgattctgtc aatgttccat tattggaaaa agctttaaat ttatatatag
     3781 aaaaaaatga agctactcgt ttacgtataa aactagtaga ctcttcacct atgcaatatg
     3841 tagcagatta ttcttatttt acaattcctg ttacaaagct aaaaaatgaa aaagaattag
     3901 aagattggaa tcaaaaaata attgatactc catttaatgt ttttgactct aatttatatt
     3961 cacttagcat ttttgtatta ccagatggac gtggtggttt taatgcaaca ttacatcacc
     4021 ttattacaga cgcttggagt atgagccttt taattactga agtaatgagt aattattcaa
     4081 atcttattca taataattct gtagattatg ttttccctaa ttatacagat tttattgacg
     4141 ctgaaaataa ttatataaat agtgagaaat tcccaaaaga tagattattc tgggacgaat
     4201 attttgaaaa ttgcccagaa ttatgctcaa tttcatcaaa caatattaat tcaaatatga
     4261 ttgctaagag aaaaagctat attttaaatt cagatttatt tgcaaaaata aatgattttt
     4321 gcaagttatt aaattgctct gtttacacat tttttatgtc tatttattct atctatttgt
     4381 ctaaactaac caatatatca gagcctatta taggtacacc agtattaaat agaacaaatt
     4441 tcaaagaaaa acatacaagt ggtatgttta ttagcactgt gccttttaaa gcaaaagttg
     4501 atagtaatat tactttttct gaatttgtaa aatctgtagc aattactcaa ttagctatat
     4561 ttaggcatca aaaataccct tattcacatc tattagaaga tttgaaaaag aaatataatt
     4621 tttcagaaaa tttatatgat attgcccttt cttatcaaaa tgctagagac aataaagaaa
     4681 attgtgatat agattattct tctggatggc tattttcagg aaaatgtaca gacacattac
     4741 aagtacattt ttatgatatg gataatacag gtgatttaaa tattttttat gattatcaac
     4801 tagataaatt aagtgatgaa gaaattaata ctttgcacga aagaataatg aatatagtta
     4861 atcaagttct tttaaataat gaaattgaaa taaaaaatat tgaaatagta actgaaaatg
     4921 aaaaagaatt cttcattagt cagtttaata acaatatttt agattattct aaagaaaaaa
     4981 gcattataga attatttgat gagcaagtta aactacatcc taacgcaatt gcagtttctg
     5041 atgataaaaa ttctatttca tatattgagt tacaaaagcg tataaatagc ctatcttatg
     5101 aattacaaaa acaaggagta aaaaaaggtg atgttgtttc tacattttta aaacgttctc
     5161 ctgagttaat aatttctcta cttgcaatta tgaaaatagg tggaatttac ttaccaattt
     5221 ctacttctct accagaagaa agagttgaat atattttaaa tgacagtaat tcgcgttgtt
     5281 gcattacagc atctaattgc tcttacttaa aaaacgtaat ttttatagat aaaataaata
     5341 atcaaaattc acaactaact cctgtaactt atttgccaga tgatgttatt tacactattt
     5401 acacttctgg ttctacagga aatccaaaag gtgttcaagt tacaaacaaa aatttaaata
     5461 actttgtttg ttcttttaac aagtattttg atcataaagt atcaacacaa gatatttgtt
     5521 tggctagtac aaatatatct tttgatgtta gtatttggga aattttcttc acattactaa
     5581 atggagctca attatattta tatgatgaag ataatatttc agatattttc cattactgtg
     5641 atgttatttt aaaacataat gttactatgt tatatatacc acctaatatt ttggaaaatg
     5701 tatattcaat tttacatgaa tctaataatg ttaaaattga taagatttta gttggagttg
     5761 agccaataaa aaattctact attcaaaagt tcttcagttt aaatgaaaat atgcaaatag
     5821 ttaatgggta tggccctact gaaacaacta tatgttgtac tgcttttaaa gtagctaaaa
     5881 aagaagcaaa tgacaattct attattccta ttggaaagcc tttatataac ttaactgcat
     5941 atgtattaaa taaggaccta aacattgtgc ctgagggtat tgctggagag ctatttattg
     6001 gtggtgataa tgttacaaaa ggttatttaa ataatgagac tttaactaat gaaaaatata
     6061 ttcaatctcc ttttaaagct gatgaaagat tatacagaac tggtgattta gtaaaattct
     6121 tacctgatgg taacttgtta tttgttggta gagatgacaa acaagttaaa gtaagaggtc
     6181 atcgtattga aataaatgaa attgaaaata ctatttcaat gtaccctaat attcaaaaat
     6241 gtattattaa tttaagaaat aataaccaag ttattgttgc atttattgtg gctagcacta
     6301 atatttcaac taaagattta aagcaatttt tattaacaaa attgcctgct tatagtgtgc
     6361 caaattttat tattcaatta gatagttttc caacaactgc aaatggaaaa attgataaaa
     6421 agcaattaaa taatattgaa attaattttt ctatgaatta tgttgctcca caaaatgagt
     6481 tgcaacaaca attagttgat atttggagtg aaatattaca agttaataat attggtattg
     6541 aagacagctt ttttgaaatt ggtggtgact ctttatcatc aataagattg gtatctgaaa
     6601 tttataataa atttggtata aagttaactg taaataatat ttttgaaaat gacacaattg
     6661 aagaccttgc agtttatatg caagctcaaa atgcctcatt agttgaaaat attgaaaaag
     6721 caaaaatatc agattcatac cctttgactt cagctcaaaa aggtatttac tatgctgtta
     6781 gcttagaaga aaatccttct attacctata atactcctgg tggaattttc ttaacaggaa
     6841 atttaaatat taaaaaactt gaagattgta ttaatacatt aattaaaaaa catgtagcac
     6901 ttagaacata ttttactatg caaaataatg aacttgtcca aaaaatagat gacaatatta
     6961 attttagttt aaaaatagaa aatggaaata ttaatgatgt tgacactatt tttgctaaat
     7021 ttgttcagcc ttttgattta agcaaggctc cactttttag aataaaatta attgaatttg
     7081 ataaaacaca ttatttgttg ttggtagatt tccaccatat tatttgtgat ggtacttcta
     7141 ttggaatttt tacagcagaa ttagtaaatt tatataatgg aaattcaatt aaagaaaata
     7201 actttgatta tattgattat gctatttttg aaaataaact aaaatcttct gaaaaatata
     7261 atcaaatgaa acaattttgg aagtcaaaat ttgatgggga acttcctgta ttaaatatgc
     7321 ctacaaattt tgcaaggcca gctaatcgct cttttgaagg tgatgaagta ttattaaata
     7381 ttacaaatgc agatgaaata tacacattgt gtaaaagtct acacaccaca ccatactttt
     7441 tcttattatc tgtttactat attcttctta gtaaatatac tagtcaagaa gatattattg
     7501 taggaactgc tgttgctgga agagatgatg caaattttgc aaatatttta ggtatgtttg
     7561 taaatacgtt ggcattacgt gaaaaaattg attctaactt atcttttaat gagtttttaa
     7621 atatagtaac tcaaactgga cttgcatgtt tagaaaatca aacttatcca tttgatgagt
     7681 tagtaaaaga attaaattta aatagaaata caaaccgagc tcctttattt gatacaatgt
     7741 ttgtatatca aaatgaagaa agtgctttaa tagacttttc aggtgttgaa acaaaacttt
     7801 ataccccatg ttctaaagtt tcaaaatttg atttttcatt agatctaacg ccaaaatcta
     7861 atgttatatc agctcgttta gaatatgcta caagtctatt tacaaaagat tttatgactc
     7921 aatttttaaa tcattatata agtttaataa aattaatttt aaatgatatt catgttacta
     7981 ttaaagaaat tagtttatta aataaagatg aaaaattaga aattgaaaaa acatataaca
     8041 gctctatttt accttatgat gaaaatgtta aattagttga attatttgaa aatgaagcag
     8101 aaaaaaatcc aaataatatt gctattcgtt tcaatggttc ttctattaca tatgaagaat
     8161 taaataaaaa ggcaaatcaa atagcaaact ttttaattag taaaaatgta aaaagaaatc
     8221 aaattgtagg aattcttctt cctcgtacac cagacttgct atttgctatg ttaggtatat
     8281 taaaatctgg tgctggttat atgttaattg atacaagttt gccatatgat cgtattagtt
     8341 ttatgctaga aaatgctcat tcaaactatt taataactaa taaagactca aaaaatattg
     8401 atggtgttga aaaactttat ttagatgaat tgcctctaga aaattatagt gcacaaaatg
     8461 taaatgccta tagtgataat gaagacagtt ttgcagttat ttatacatct ggctctactg
     8521 gcactccaaa aggtgtagag ttaaaacgaa aaggtgttat aaatatgcta agtaattata
     8581 aagcttttct ttatactgat acttgtacaa actttttaag tatgagtagt gtagcatttg
     8641 atatgtttat tgtagaaaac tttgtgccat tactttctgg taaaactgta atattaacaa
     8701 atgaagaaga acaaaaaata ccattatata caaacacatt aatagagcaa gaacatgtaa
     8761 actttatttt aactactcct tctagaatgg acttattact ttctgtaggt tcaaattgga
     8821 atactataaa agttatacaa ttaggtggag aagtttttcc ttcaaattta tatgataaaa
     8881 taaaagctca aacttctaat gctcatatat ttaatggtta tggtccttct gaaattactg
     8941 cttgttgtac aagtaaagaa gtttacaatt ctaatgatat aactattggt aagccatttg
     9001 ctaatacaca attgtggatt tgtaataaag atttaaacat atgccctatt ggtgttgaag
     9061 gtgaaatttg tgttgcaggt cttggagttg gtaaaggtta tattaataac cctgatttaa
     9121 ctaataaaag ttttgtacca aatccttttg gagatggaat tatgtacaaa actggtgaca
     9181 ttggaaaata caaatctaat ggtgatattg agtttattgg cagaagagat tcacaaatta
     9241 aaatacgtgg ccttagggtt gaattatctg aaattgaaaa tcagtttttg aaaatacctg
     9301 aaataactaa tatttgtata atttataaaa aagaaactgt accttattta gctgcatttt
     9361 tcacatcatc tggtgagatt gaaacatcag taataagaaa gcagttgtct gaaaccttac
     9421 cattatatat ggtgccaaaa tatattataa aattagacaa gcttccaatt actttaaatg
     9481 gtaaaataga taaaaaacaa ttagaaaatt attctataag ccaagttgaa actagaacct
     9541 atgttgcacc tagaaatgag actgaaaaac tatgttgtaa catatgggaa agccttttaa
     9601 actgtcaaat tggtattgat gatgatatat ttgaaatggg tgctgactct ttacttgcaa
     9661 ttaaattcaa aacagaatta ttagcttata atattaatat tacatattct gatattttta
     9721 aatatcatac agttagagag cttgtaagca cacatggcga atatgatatt gaattattag
     9781 ataacaaaga ttttgttgaa tgccataatg cattagaaaa aaatgttgca tctaattttg
     9841 ctacatctct ttctaactta cagtcttcaa gttataacaa tattttacta ttaggagcta
     9901 atggatttgt tggtagccat attttatata gttttattaa aaatgatact ggtaatgctt
     9961 attgcattgt tcgtgacaaa gacagaaaag aaggaaaaac tagattttta gaaacattac
    10021 atttctactt tggaaatgaa ttagaccatt atttaaataa tagaattttt gttattaatt
    10081 ctagtatttt agatgaaaac tttggtatga gtgaaaaaga ttatttagaa ttgcttaata
    10141 gcattgatgt tattattaat tcagctgcaa ttgtaaaaca ctatggtaat gaggaaaaat
    10201 ttaaaaaaat aaatgttggt ttaacagaaa aacttattga tatatgtaca aagttcaata
    10261 aaagattact tcatgtctct tctttaagtg tatctggaaa tttatcttta gatggtagtt
    10321 atgcagatag aatacatgaa gttactgaga atatgaattt ttctgagcat aatttatata
    10381 ttggtcaaat tctagataat gaatatatta aaagtaaatt tttatctgaa aaattgatat
    10441 tagaaaatat aagtaaaaat ggtttgcaag cacaaatttt acgtttaggc aacattacta
    10501 atagatattc agatggtgct tttcaaataa attaccaaga aaatgcattt ttggaacgta
    10561 tgcttacatt tatagagctt ggttatgttc caaataatct attggatatg tatattgaat
    10621 tcacaccagt tgatgtttgt ggtaatgcaa taataaaaat tttacaaaac tatgtacctg
    10681 atttttcagt atatcattta tataatgata atcatgtgta tatgaatgaa tttttgaaaa
    10741 ttcttcaaga agaaaatatt aatattgttt ctgtttctcc tgaggagttt ggtaaaaaaa
    10801 ttacagactt gtcaaaaaat gcaaaaagtg ctaatatact ttctggaatt ataaatgatt
    10861 taggaccaga taaacaatta gagtataaat ctaatattaa tattctttca gattttacta
    10921 aagcattttt ataccatatt aattttaaat ggcctaaaat cgatgaatca tatttgaaaa
    10981 aatatattaa ctatttaaga aaatatttag cctaaaagtt gatagatgta taattatata
    11041 catctatcaa atgtatttat ttaaaggagt attaaactta tgaaaaattt aaactatttg
    11101 gttattctta ttatatctgc aataattatg actgtattat tgttagttat taaaaaaact
    11161 caaaaaacta aaaaacaaat ttattattct ttcataactt tagttggttt aatgttagtt
    11221 tggacaatta gtttaattat gcaaattctg tgtcaaaata catctattcc gcctgtatat
    11281 tttgaatata ctgctgcttt tggtggatgt tttttatctg ttgcattttt cttttttgca
    11341 ttaattatgt ctaaaacaaa aattaaattt aagctttggt atttgctttt atttgttata
    11401 cctatacttt catgtatttg cttatggaca aatgatttcc accatttatt ttatgcaaaa
    11461 tactctatta atttaaatga tactgtaaag ggcccattta taatggtcca ttcagtttat
    11521 acatttgctt tattaatact tgctatattt atattattta aatactcatt taaaacatca
    11581 ggtttctttt ctaagcaatc attattaatt gttttaggag ctcttattcc tttagttatt
    11641 aatttgcttg gaatgcttgg tatacctatg acagtatatt taacgcctat atgttttgca
    11701 cttacaattt tattttttgc attggctgta tttaggtttg gattaatgaa agtaacccca
    11761 atagcattgc aaacaattgc ggataaaatt tcagatggtt acttagtttt ggatgaaaat
    11821 ggtattatta cagattttaa tgctacagta ttaaaaatgt ttaagcttga tgggaattac
    11881 attagaggaa aaaacttatt tgatatagta aatacaggaa attatttttc tgttaacact
    11941 gaaaaattaa aaaactgtat tgatattgca aaagatactc ctgatacatt tcattttgaa
    12001 aaaaaattag ttaatgaaga caaatatttt aatatagaaa ttaatagtat tcaaaatgat
    12061 aaaacttttc taggaatttt agtattattt aaagatacaa ctcaacatat gcttgatatg
    12121 caaacaatta aaaataatca aaatatgctt atggaaagag aacgtttagc ttcacttggt
    12181 cagttaattg gtggtatagc tcacaactta aaaactccta taatgtctat atctggtgca
    12241 gctgaaggtc ttacagattt agttaaagaa tatgaagcat ctgtaggaga ccctgaggtt
    12301 actgtacaag atcaccatga tattgcaaaa gacatgaagg attggataga caaaatacgt
    12361 tcttatacag aatatatgtc agatgttatt actgctgtta aaggccaggc tgttacaatg
    12421 tctgaagaac aagctgtatc atttacttta gacgaattag ttaaacgtgt aaatatttta
    12481 atgaaacatg aattaaaaaa tgccttagta gagctaaatg tttgcatgaa aacagatgaa
    12541 agaactgtat taaaaggaaa tataaacagt ttggtacaag ttataaataa catggtttca
    12601 aatgctatac aatcatatga tggtaaacct gataataaaa ttgatttaat tttatcaaaa
    12661 caaaataata atgttgttat ttctgtaaaa gattatggaa atggcttacc agatgaagtt
    12721 caaaagaaat tatttaaaga aatgataaca acaaaaggta aaaatggtac tggacttgga
    12781 ttatttatgt catactctac tattcgtgct cattttaatg gcaatattac ttttgaaaca
    12841 gaaaaaggaa aaggaactac atttaatgta atcctaccac tttaatattt actcatatgt
    12901 ataaaatcta gtgttttcaa ctaaatgcta gatttttttt atgcaaaagc tgtacaattc
    12961 gacaagttat gatataatga tgttgtcatc ttgaatagat tacaataaac gttgaggtga
    13021 gattatgaga aaaaacatgc aaagcgcaaa tgataaaggt tatagaatta tagcagttga
    13081 tgatgaggaa ggaattgttg attctttatc aattttctta aagagatctg gctatgattt
    13141 tacaggtgtt actgacccaa tggaagcaat tgaaaaggtt aaaaatgaac attttgattt
    13201 aatgattttg gactttatta tgacacctat tcatggagat caggtagttg aagaaatacg
    13261 taaattcaat aaggaattat atattttgtt actaactggt cataaagatt tggctccacc
    13321 tttggaaaca attagaaaat tagatattca aggttattgt gaaaaaagtg ataaatttga
    13381 tcaattactt cttttaattg agtctggaat taagtcaatt gagcaaatga atgaaataaa
    13441 aagaataaat gaagagcttt cttctactta tgaaaaacta gaaagagcct acttagacag
    13501 tattcaaact ttaagatata ctgttgaagc taaagaccca tataccagag gacattcaga
    13561 tagggtttct aagtattctg ttttaattgg aaaatattta ggattatctg atactgattt
    13621 aaaaactcta gaagttggtg gtttattcca tgatattgga aaaattggta ttcctgatag
    13681 tattttatta aaggaatcta aattgacaga tgatgaatat tcacaaataa aaaaccatcc
    13741 ttcaataggt gctcatattt tgtgtaatgc tgaagttttt caagatatta taccaattgt
    13801 aaagcatcat catgaaagat ttgacgggac tggttaccct ggaaaactaa aaggcaacga
    13861 tattccttat cttgcgagaa tagctgctgt tgcagatact tttgatgcta tgacatcaag
    13921 gagaacttat cgtgatcctt taagtttaga tgttgtaaaa gctgaatttg aaagatgctc
    13981 tggaacacaa tttgacccag aaattgcaaa agtattttta gatattttaa ataatcatta
    14041 tgatgaagta aatgaaattc aagaacaatt taaataaggg gatattctat gtttaaagtt
    14101 ttagttctat catgtagtac aggtggtggc cataattctg ctgcaagtgc tataacagag
    14161 gaattaagaa ataaaggagt tcaagttgat tttaaagaat atttggactt aataaattat
    14221 aagatagcta atgttgtaaa taaattatat attagttcaa caaaaggaaa tggtgctgtt
    14281 tttaaaagag tttataaact aggtgaatta tatgaaaaga caaaaattac atctccggtt
    14341 tatggtgtaa ataaattaca tagaagaaaa ttatataatt atattgttga aaataaatat
    14401 gattatgttg tagttactca cctattccct gctgaagttt taactgctat taaaaaacaa
    14461 catgacatac attttattgc agttgcaaca gattataaat caattccatt ttggccagaa
    14521 actaatccag actattttat aattccacat aaagatttaa ttgaagattt tactaaaaaa
    14581 ggtatcagcc acgaaaagct aatacctttt ggtattcctg tgtcaactaa ttttagtaaa
    14641 gatttagata aatctaaaat atttgctgaa ttaaatctag ataaaaataa aaaatatata
    14701 ttagttatga caggaagtat gggttttgga aatgttacag gtataataga tgttttacag
    14761 aatgaaattt ctgaaacaat tttagttgcc tgtggtaata ataaaaaagt ttatgaagat
    14821 atttcaaata attataactc aaataaagta attcctatag gttttactcc acaaatttat
    14881 aaatatatga ctataagtga gcttttatta actaagcctg gtggtcttac aacaacagaa
    14941 gctgccacaa taaatattcc tattattcat actatgccaa tacctggctg tgaaacatat
    15001 aatgcagaat tttttgggag tcatggaatg tctatcagct gtaagaatac taatgatata
    15061 aaaaatgcag taatatctct tttaactgat aaaaataaaa tggaaaatat aataaaagca
    15121 caaaaacaaa atatagataa aaatgcttgt agcaaaattt gtgaatttat aatagatgaa
    15181 ataaggaaat atagtaaatg aaagaaaatt tacaatcaaa tgtaaataat gaaaatgaag
    15241 atataataaa aatgtgggaa ccacttaaat ttgatattgg cttaaattat aaatatgtaa
    15301 aaaataatat attttttaag ttaatatcaa atttatttta ctacatcata gttgcaccaa
    15361 ttattttttt aatttctaac attatttttg gactaaaaat tgaaggaaaa gaaaatttaa
    15421 aaaatattaa gactggtgct atttcagtat caaaccatgt gcaatatata gattgtgcaa
    15481 tgcttggtct tgcatggttt cctagaagaa tatattacac tgctaaaact gatggtttta
    15541 aaatgcctgt ggttaggcat ttagtacgtt tgttatatgc tattcctata ccagaaaaaa
    15601 tttcttgtaa agaaaatttt tataaagcaa ttgatgattt attagctaaa aataaagtag
    15661 tacattttta ccctgaagct tctttgtggc catattacaa taaattacgt aattttaaaa
    15721 atggtgcatt taaaattgct tcaaaaaata atgtaccaat tattccattt gtgtttagtt
    15781 ttagaaagcc aactggtatt ttaaagcttt ttaaatctaa accttgctta attttaagtg
    15841 ttctaccacc tgtttatcca aaacaaaatt tagcatttaa tgaaaggtat ttagatttaa
    15901 aagaaaatgt atacaaaaaa atgagtgaaa aaatataa
//
