BGC0001692: nematophin biosynthetic gene cluster from Xenorhabdus nematophila ATCC 19061
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Location: 2,151,233 - 2,184,146 nt. (total: 32,914 nt).
This entry is originally from NCBI GenBank NC_014228.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001692
Short description nematophin biosynthetic gene cluster from Xenorhabdus nematophila ATCC 19061
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "Overlaps, and possibly shares genes with rhabdopeptides (BGC0000416)."
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: NC_014228.1
Compounds
  • nematophin
Species Xenorhabdus nematophila ATCC 19061 [taxonomy]
References
Chemical products information
nematophin
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C16H20N2O2
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • XNC1_RS09375
  • WP_013184315.1
  • pntA
 2151233 - 2152765 (+) Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha
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  • XNC1_RS09380
  • WP_013184316.1
  • pntB
 2152776 - 2154164 (+) Re/Si-specific NAD(P)(+) transhydrogenase subunit beta
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  • XNC1_RS20595
  • WP_013184317.1
 2154724 - 2159406 (+) non-ribosomal peptide synthetase
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  • XNC1_RS09390
  • WP_013184318.1
 2159403 - 2164067 (+) non-ribosomal peptide synthetase
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  • XNC1_RS09395
  • WP_013184319.1
 2164064 - 2170060 (+) non-ribosomal peptide synthetase
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  • XNC1_RS22865
  • WP_065814203.1
 2170616 - 2170927 (+) transposase
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  • XNC1_RS09410
  • WP_013184322.1
 2170947 - 2175158 (+) non-ribosomal peptide synthetase
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  • XNC1_RS09415
  • WP_230333026.1
 2175711 - 2176634 (+) tyrosine-type recombinase/integrase
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  • XNC1_RS09420
  • WP_010845792.1
 2176919 - 2177797 (+) DMT family transporter
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  • XNC1_RS09425
  • WP_013184323.1
 2178002 - 2179093 (+) amidinotransferase
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  • XNC1_RS09430
  • WP_013184324.1
 2179205 - 2180137 (+) fatty acid desaturase
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  • XNC1_RS09435
  • WP_010845795.1
 2180220 - 2181083 (+) hypothetical protein
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  • XNC1_RS09440
  • WP_010845796.1
  • uspE
 2181151 - 2182095 (-) universal stress protein UspE
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  • XNC1_RS09445
  • WP_010845797.1
 2182223 - 2182987 (-) FNR family transcription factor
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  • XNC1_RS09450
  • WP_010845798.1
 2183253 - 2184146 (+) dimethyl sulfoxide reductase anchor subunit
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
XNC1_RS20595
Module ?
Specificity: leucine
Evidence for specificity:
XNC1_RS09390
Module ?
Specificity: valine
Evidence for specificity:
XNC1_RS09395
Module ?
Specificity: valine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Add note about possible overlap with BGC0000416
Detailed domain annotation
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