LOCUS       BGC0001696              9985 bp    DNA     linear   BCT 22-MAY-2018
DEFINITION  Streptomyces sp. DNA, neothioviridamide biosynthetic gene cluster,
            strain: MSB090213SC12.
ACCESSION   BGC0001696
VERSION     BGC0001696
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:05:26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9985
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..264
                     /gene="ntvA"
     CDS             1..264
                     /codon_start=1
                     /gene="ntvA"
                     /product="precursor peptide"
                     /protein_id="BBC15198.1"
                     /transl_table=11
                     /translation="MSEAMVSAVDEAAFADLVSKIQDAEASMTDEQRAVIDPAAGEKAL
                     EELAGVSPEELQAFLEEKAGISPDEEAQGSVMAAAATVAFHC"
     source          1..9985
                     /collected_by="Kazuo Shin-ya"
                     /collection_date="2009-02-13"
                     /country="Japan:Okinawa, Ishigaki"
                     /db_xref="taxon:1931"
                     /isolation_source="mangrove soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp."
                     /strain="MSB090213SC12"
     subregion       1..9985
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="ribosomal"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..9985
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            480..1439
                     /gene="ntvB"
     CDS             480..1439
                     /codon_start=1
                     /gene="ntvB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /product="phosphotransferase family protein"
                     /protein_id="BBC15199.1"
                     /sec_met_domain="APH (E-value: 5e-16, bitscore: 48.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHFEDGTALVLKQVNPATARAVGTAAGNEETMLKLIPESGVPHF
                     AGSAVPRFIAADPETSTLIMEGKTGFTSMREATRNFPEIPVPVLAALASVTAGIHATPV
                     DQIVADERFERQRIAFPFASFVVLTPGELASGPGMDYSDYVAAMQSVDESVALLRDGWG
                     PKGLVHFDLRDDNILLKDADGERPGVALVDWELAGFGDPMLDVGTIVGQLLIQWLHTLR
                     GDAARLSDSGSWATVRRNVGLFLAAYEHGAALSTEQRDAVFRYAGLSTLMYAAGRLEQI
                     GSLGRIGHLCLFVGCKLLNDPQGLAGVLVPSHPRKARA"
     gene            1436..2440
                     /gene="ntvC"
     CDS             1436..2440
                     /codon_start=1
                     /gene="ntvC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: HopA1"
                     /gene_kind="biosynthetic"
                     /product="hypothetical protein"
                     /protein_id="BBC15200.1"
                     /sec_met_domain="HopA1 (E-value: 3.7e-52, bitscore: 166.1,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRYQAVFSAIAEDVEVLSESAFHHREWGELRPAPGVESAPGDLP
                     VLPHLSRFLYLSYYAGDTRAARWLIDGAPVVLGTRRREDPAVARALTEANQGSGYWDAD
                     WHTVTTGPEGSQVRKNGVTLTVTTKESLPTTAVPGQRVSVRFPPHRPYTYPGWYLAIGD
                     EGMPRHGEQPVVRLYYAPRGPAAAADLMRAITGRLCSAGVPYQLKAANHPEGYERRDAM
                     VLYLYRESWRSHEPELTDVHREHLHALRDTGPALALELGRGWWLADEPEQRQGRLMSFG
                     QHRCLLVAEGLLTAWREGRTTAADRLRAVEERYRAERLDPAKPYLNAQGSSVQ"
     gene            2437..3378
                     /gene="ntvD"
     CDS             2437..3378
                     /codon_start=1
                     /gene="ntvD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /product="phosphotransferase family protein"
                     /protein_id="BBC15201.1"
                     /sec_met_domain="APH (E-value: 1.7e-10, bitscore: 30.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAAVRTGQPVRSIPGPFVNRVCLRVDGGYRWGESVPAAAPAYL
                     DAALLGGLARAIASMRDAAYACVPVLTDDRTAVHQVVATPGLLSDTVFGSSAGAATRQP
                     EQTFEQLGDFLAQLHSLPVEQVATLPTRTCPAWLAAMPDAADGIRAARDRLDTAAAPRI
                     RHLAGAMTAEAPGALPRAVVHGRLSTASCVPGPAPRVLGWREAGIADPMTDLAFLLRDL
                     VQSAAALGEQELQEQRARLAAEGYQKARGAPLSNDEHARLAGHLASGVLQHVALRAWSA
                     SDPEGAEALLRRAEECLPGILGAVGAPQEVTG"
     gene            3378..3980
                     /gene="ntvE"
     CDS             3378..3980
                     /codon_start=1
                     /gene="ntvE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /product="decarboxylase"
                     /protein_id="BBC15202.1"
                     /sec_met_domain="Flavoprotein (E-value: 1.1e-29, bitscore:
                     92.6, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHTSPRQALAEVKLLWGVCGSFSAVAVPHVNAWLRGTVGVQQI
                     RTIMTAQAHALLGPRMIEAVTGHMPVTDWEDHKGGGAAHVALGTWADVLVVLPATANFL
                     AKAAHGIADDVLTATLLAAECPVVIAPVMNAAMWSKPAVRRNVDQLREDGYRIVEPKEG
                     VSLTEGRREAGSLGDFQPVISAALVRAATRHTHPQGQ"
     gene            3988..5205
                     /gene="ntvF"
     CDS             3988..5205
                     /codon_start=1
                     /gene="ntvF"
                     /product="methyltransferase"
                     /protein_id="BBC15203.1"
                     /transl_table=11
                     /translation="MPKLSPDTVLHRAPSFIAEVDTSNEVKIHFESRVLKLGHDALGLL
                     DLFHQPRTVGQALTLLGPRLKGPRAAQEALTTVASLHQAGLLRNEPTEGFSNQPFPKGG
                     YDAGLVHIAMLEDPVRKATFQQAVRETVRDGDVVLDLGTGSGILAITAAQAGARKVYAV
                     EPAGMVHLARRIAERNGVADRIEFIRGWSPQLELPERADVLLTDIVGNESLDMQIWETV
                     QDARRRLMKDAPRLVPGRLTSFATLARIPNGVLDKHRVTQDHLARWKEMFGIDFGPMAE
                     SESRRSIGFYERPETVQTWDFFSKPAELYQVDLQQDMTGPLATRCTLDVDRAGEANGVV
                     VHFEARLGPNTTLSTAPWLGSARSHWYTAVWALPEPVKVSPGQELAYSYRYFGDGVSHL
                     EPVSGQ"
     gene            5243..6595
                     /gene="ntvG"
     CDS             5243..6595
                     /codon_start=1
                     /gene="ntvG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /product="YcaO-like protein"
                     /protein_id="BBC15204.1"
                     /sec_met_domain="YcaO (E-value: 1.2e-73, bitscore: 238.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRSSVPKITGNGPHREITAETTYARMAPHLKRIGVTRVADITG
                     LDRVGIPVYNAISPRSFDIISVYNGKGATKIDAKTSAVMEAVERFAASLPMRPAAIASY
                     PELKKSGRRVLDPRSCNFELHHAYSIDTPISWVEGFDLMHESSVLVPQFLAGYYMSYHE
                     VPCYPVSTTNGIASGNSLEEAVCHALCELVERDDWTMADLVSNRLGKFVADDGAGPIGD
                     AIRAWAQERHPSLDPSTLPPRAQFFLEKFLDAEIAIEVKNITSATGIPSFQAVVSEYVA
                     DSFSRSHHGIGTHPDAEVAVVRAISEVAQSRVVDIQAMREDITAAGQPVEKALYHVRRS
                     NRANPDSWAIKPSASAVRFQDVPSHPSTDVMDDVRLLLQRLRARGLDQAIVVDLSAPGV
                     PATVVRVIVPGIESWTVDRNKLGPRATQAWNSALAAIHSAQQRLRTAGSAQ"
     gene            6610..7299
                     /gene="ntvH"
     CDS             6610..7299
                     /codon_start=1
                     /gene="ntvH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /product="TfuA-like protein"
                     /protein_id="BBC15205.1"
                     /sec_met_domain="TfuA (E-value: 6.7e-45, bitscore: 141.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVVFVGPSLPPEEAAAHLPGAEFLPPIERGDIDALMAEEQPPR
                     RIGIIDGKFLQSFSISPKEVLRAMDRGVRVYGSSSMGALRAAELDVYGMTGVGTVYAMY
                     ASGALEDDDEVAITFDDESLRPVCEPMVNIRVAMEAAQRRSVVSQENAELFLKTAKSLY
                     FPQRTSSAALHQLKGIMPEPDRQRLADYLRSPDAPDAKRDDAVSLLARMRQDAEAYDAG
                     PAPEVAL"
     gene            7299..8177
                     /gene="ntvI"
     CDS             7299..8177
                     /codon_start=1
                     /gene="ntvI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /product="phytanoyl-CoA dioxigenase"
                     /protein_id="BBC15206.1"
                     /sec_met_domain="PhyH (E-value: 5e-28, bitscore: 88.3,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATIAPDLAERFRTDGFAFPVNALTRAEAEQALAECHAYLRTVSA
                     AGGALARYATFPKIHLVSTWADRIVHHPAILDAAEALLGPDLLVWSTNLFVRPARSGSS
                     LAWHQDAVYLGLNGFQQHAARVWVALTDTTVANGTMRYARGSHLGGALPHRFSGSELED
                     IMRGEEIAVDIDEEAAVDVILNAGQCSVHHLAMAHCSGPNHTANGRFNLAIDFVGPQVS
                     PTTGEDSALLVRGTDTGAFLPESRPAADFDGAALSQFYAAVARRQKRIDQVVLHRNGED
                     GGGAGRIRDRA"
     gene            8174..9001
                     /gene="ntvJ"
     CDS             8174..9001
                     /codon_start=1
                     /gene="ntvJ"
                     /product="peptidase"
                     /protein_id="BBC15207.1"
                     /transl_table=11
                     /translation="MTKAGTTGKDATPGPAADGTWLSRIVPPWWTSGRTPEHMDLSSWM
                     PPVIDQGQVPLCTAAVTTAIAGYYARRSEHTEFTASVLFNYRLSRVLAGSAERKGSRLE
                     HSFRAWAESGLCEEAAWPYDEHGLSRVDRDPPEHCHTTARRTEPVAQVLSAPDGVGLLE
                     LARRAIALGLPVSVEIRLCPSISMSLVNGGIVPVQLTTEQSVGPHVVLLTGYDDRADTA
                     PYDRGTGPGAFRVRNSWGTGWGTKGYGLLPYAFFEQQLTGESWVVVERDWQKQ"
     gene            9143..9985
                     /gene="ntvK"
     CDS             9143..9985
                     /codon_start=1
                     /gene="ntvK"
                     /product="hypothetical protein"
                     /protein_id="BBC15208.1"
                     /transl_table=11
                     /translation="MTLRKFLVAAARWAAPTVVLAQVCLVWTGVFSLGEAVAVGLALEL
                     LLAGIVITEITLARRAFKASRSQGADGQEALNQALSAVLPGPVAKAMGMEFGLFRALWR
                     WMRRKPDAPEDHAILTYGSEIKPIMWVMVFLVPLEILAVEFLVPWPVVRITLLILSVYG
                     TVWVLGFIAALSIRPHTIGDGKMVLRFAHFTQIVVPLELVESVSTARHSGYRRAIQIDD
                     GVLAMPIGDSTTLSVKLREPYPLAPKPGQPVQEVHEVRFAADNTREAVRVLTASIADA"
ORIGIN
        1 gtgtctgaag caatggtttc cgcggtcgac gaggccgcgt tcgccgacct cgtcagcaag
       61 atccaggacg ccgaggcgtc gatgaccgat gagcagcgcg cggtcatcga ccccgcggcc
      121 ggcgagaagg ccctggagga gctcgccggc gtcagcccgg aggagctgca ggcgttcctt
      181 gaggagaagg cgggcatctc gcccgacgag gaggcgcagg gcagcgtgat ggcggctgcc
      241 gccacggtgg ccttccactg ttgatctgag gcgttcacct catgatgacc agcgcttcgc
      301 acagcccgac cggcatggtg ctgccggcgg gcggcagtac gtcttcgcct tggtgcggag
      361 cgctgccgga cgagtccggg ccagcaaagg cccgggctcg ttcccggctc gcttcgctcg
      421 gtatcgaccg aggcgaaatt gtacgcatcc ggacgttcgc agcacgcaac agcgtgacga
      481 tgttgcactt cgaggacggc accgcgctcg tcctgaaaca ggtcaatccg gcaaccgcca
      541 gggcagtcgg cacagcagca ggcaacgagg aaaccatgct gaagctgata cccgaatccg
      601 gcgttccgca tttcgccggg tcggcggttc cccgtttcat cgcagccgat cccgaaacct
      661 cgaccctcat catggagggg aaaaccggat tcacgtcgat gcgggaagcg actcggaact
      721 ttccagaaat acctgttccc gtgctggccg cattggcatc agtgacggca gggattcacg
      781 ccacgcccgt ggaccagatc gtcgcggacg agaggttcga gcggcagcgc atcgccttcc
      841 cgttcgcttc cttcgtggtg ctcacccccg gtgaactcgc gagcgggccc ggaatggact
      901 actccgacta cgtggccgcc atgcagtcgg tcgacgagag cgtggcgctg ttgcgggacg
      961 gatggggccc gaaggggttg gtccacttcg acctccggga cgacaacatc ctgctcaagg
     1021 acgccgacgg cgaacgcccc ggggttgcgc tggtggactg ggagctggcc gggttcggcg
     1081 accccatgct ggacgtgggt acgatcgtcg gtcaactgct gatccaatgg ctgcacacct
     1141 tgcggggtga cgccgcccgc ctctccgact cgggcagttg ggccaccgta cgacgcaacg
     1201 tcggcctctt cctcgccgcc tacgaacacg gtgccgcgct ctcgaccgaa caacgggatg
     1261 cggtcttccg ctatgccggg ttgtccaccc tgatgtacgc agccgggcga ctggaacaga
     1321 tcggctcgct gggtcgaatc gggcatctgt gccttttcgt gggctgcaag ctactgaacg
     1381 atccgcaggg cctggccggg gtcctcgttc ccagccaccc ccggaaggcg cgagcatgaa
     1441 ccggtaccag gcggtgttct ccgcgatcgc tgaagacgtg gaggtcctga gcgaatcggc
     1501 cttccaccac cgtgagtggg gcgagctccg acccgcgccc ggcgtcgagt ccgcccccgg
     1561 ggacctcccc gtccttcccc acttgtcccg cttcctctat ctgagctact acgccggtga
     1621 cacccgagcc gcgcgctggc tgatcgacgg cgcacccgtg gtgctgggca cccgcaggcg
     1681 tgaggacccg gccgtggcac gggcgctcac cgaggccaac cagggcagcg gctactggga
     1741 cgcagactgg cacacggtca cgaccgggcc cgagggcagc caggtgcgca agaacggcgt
     1801 gaccctgacc gtcaccacga aggagagcct tccgaccacg gccgtgcccg gtcagcgggt
     1861 gagcgtcaga ttcccgccgc accgcccgta cacgtacccc ggctggtacc tcgccatcgg
     1921 cgacgagggc atgccccgcc acggcgaaca accggtcgtg cgcctctact acgcgccccg
     1981 agggccggca gccgccgccg atctgatgcg cgcgatcacc gggcgactgt gctcggcggg
     2041 ggtcccgtac cagctgaagg cggccaacca cccggaaggg tacgagcggc gagacgcgat
     2101 ggtcctctat ctgtaccggg aaagctggcg cagccacgag ccggagctga cggacgtcca
     2161 ccgcgagcat ctccacgccc tccgtgacac aggccccgcc ctcgcactgg aactgggcag
     2221 aggctggtgg ctggcggacg agccggaaca acggcagggc cggctcatga gcttcggaca
     2281 gcaccgctgc ctgttggtgg ccgaagggct gttgacggcc tggcgggaag gccgcaccac
     2341 tgcggcagac cgcctgcggg ccgtcgaaga acggtaccga gcggagcggc tcgaccccgc
     2401 gaagccctac ctgaacgccc aagggagcag cgtgcaatga cccaagccgc cgtgcggacc
     2461 gggcagccgg tccgctcgat tcccggcccg ttcgtcaacc gcgtctgcct acgggtcgac
     2521 ggtggatacc ggtggggaga gagcgtcccg gcagccgcgc ccgcttatct ggacgccgcc
     2581 ctcctaggcg gtctcgcccg ggcgatcgcg tcgatgcggg acgccgccta cgcgtgtgtc
     2641 cccgtgctga ccgacgaccg cacggcagtc caccaggtgg tggccactcc cgggctgctg
     2701 agcgataccg tcttcggcag ctcggccggc gcagccaccc ggcagccgga gcagacgttc
     2761 gagcagctcg gcgacttcct cgcacagttg cattcgctcc ccgtcgaaca ggtggcgaca
     2821 ctccccacca ggacctgtcc tgcctggctc gcagcgatgc cggacgcggc ggacggcatc
     2881 cgcgccgcac gcgaccgtct cgacacagca gcggcccccc gtatccggca cctcgccggt
     2941 gccatgacgg cagaagcgcc cggtgcgctc ccacgggcgg tggtgcacgg gcggctgtcg
     3001 accgcttcct gcgttcccgg tccggcgcca cgcgtgctcg gctggcggga ggcaggcatc
     3061 gccgacccca tgaccgatct cgccttcctg ctccgggacc tcgttcaatc ggcagccgcc
     3121 ctgggcgaac aggaactcca ggagcagcgg gcccggctcg cggccgaggg ctaccagaag
     3181 gcccgcggcg cgccgctgag caacgatgaa cacgcacgtc tcgccggcca cctcgcctcc
     3241 ggcgtgctcc agcacgtggc cttgcgcgcc tggtcggcgt ccgatccgga aggcgctgag
     3301 gcactactac gacgggcaga agagtgcttg ccgggaatcc tcggcgccgt cggggctccc
     3361 caggaggtga ccggctgatg accgagcaca ccagccctcg gcaggctctg gccgaggtga
     3421 agctgttgtg gggagtgtgc gggtccttct ccgcggttgc cgtcccccat gtgaacgcct
     3481 ggctacgcgg cacggtcggg gtccagcaga tccgcaccat catgaccgca caggcacacg
     3541 ctctcctggg gccacgcatg atcgaggcgg tcaccggcca tatgccggtg accgactggg
     3601 aggaccacaa gggtggaggc gccgctcacg tcgccctggg cacctgggcg gacgtgttgg
     3661 tggtcctgcc ggccaccgcc aactttctgg ccaaggcagc acacggcatc gcggacgacg
     3721 tcctgacggc cacactgctg gccgccgagt gccccgtggt gatcgccccc gtcatgaatg
     3781 cggccatgtg gtccaagccg gccgtacgcc gcaacgtcga ccagctccgc gaggacggct
     3841 accggatcgt cgaaccgaag gagggtgtct ccctcaccga ggggcggcgg gaagccggtt
     3901 cgctcggcga tttccaaccc gtgatctccg ccgccctggt ccgggccgcc acacgacaca
     3961 cccacccaca aggacagtga tcagtacatg ccgaagctct cgcccgacac cgtgctccac
     4021 agggcgccgt ccttcatcgc cgaggtcgac accagcaacg aagtgaagat tcactttgaa
     4081 agccgggtcc tcaaactggg tcatgatgca ctcgggctcc tcgacctctt ccaccagccg
     4141 cgtacggtcg gacaagcgct gaccctgctc gggccgaggt tgaaaggtcc cagggccgcg
     4201 caggaagcac tcaccaccgt ggcctcgctc caccaggccg ggctgctgcg caacgagccg
     4261 accgaagggt tcagcaacca gcccttcccc aagggcgggt acgacgccgg actcgtccac
     4321 atcgccatgt tggaagaccc ggtgcgcaag gcgaccttcc agcaggcggt ccgtgaaacg
     4381 gtccgtgacg gggacgtggt cctcgacctg ggaaccgggt ccggcatcct ggcgatcacc
     4441 gcggctcagg ccggagcccg caaggtctac gcggtcgagc cggccggcat ggtccatctc
     4501 gcccggcgga tcgcggaacg caacggcgtg gccgatcgca tcgagttcat ccggggctgg
     4561 tcgccccagc tcgaactgcc cgagcgggcc gacgtcctgc tgacggacat cgtcggcaac
     4621 gaatccctgg acatgcagat ctgggagacg gtccaggacg ccagacgccg gctgatgaag
     4681 gacgcgcccc ggctggtccc cggccggctg acctcctttg cgacactggc ccggataccg
     4741 aacggggtgc tcgacaagca ccgtgtcacc caggaccacc tcgctcggtg gaaggagatg
     4801 ttcggcatcg acttcggccc catggcggag tccgaaagcc ggcgctccat cggcttttac
     4861 gagcgcccgg agaccgtgca gacctgggac ttcttctcca agccggccga gttgtaccag
     4921 gtggacctcc agcaggacat gacggggccg ctggcgaccc gttgcaccct cgacgtcgat
     4981 cgcgcgggtg aggccaacgg ggtcgtcgtc cacttcgaag cacggctcgg gccgaacacc
     5041 acgctgtcga cggccccctg gctggggagc gcccgcagtc actggtacac cgcggtctgg
     5101 gctcttcccg aaccggtcaa ggtctccccc ggtcaggaac tcgcctattc ctaccggtac
     5161 ttcggcgatg gcgtctccca cctcgaaccc gtcagcggcc agtgaccggc ctaccggaca
     5221 gcgcatccaa ggagcccctg cgttgaaact gcgttccagc gtccccaaga tcaccggcaa
     5281 cggcccgcac cgcgagatca ctgccgaaac cacgtacgcg cgtatggccc cgcacctcaa
     5341 gcggatcggg gtgaccaggg tcgccgacat caccggcctc gaccgggtcg gcatacccgt
     5401 ctacaacgcc atctccccac ggtcgttcga catcatctcc gtctacaacg gcaagggcgc
     5461 cacgaagatc gacgccaaga cctcggccgt catggaagcc gtcgagcgct tcgccgcctc
     5521 cctgcccatg cgaccggccg ccatcgcctc gtacccggaa ctcaagaagt ccggacgccg
     5581 cgtgctcgat ccccgatcgt gcaacttcga actgcaccac gcctacagca tcgacacccc
     5641 catctcctgg gtcgaaggct tcgacctgat gcacgagtcc agcgtcctcg tgccgcagtt
     5701 tctggccggc tactacatga gttaccacga agtcccctgc tacccggtct ccacgaccaa
     5761 cggcatcgct tcgggaaact ccctggaaga agccgtctgc cacgctctgt gtgagctcgt
     5821 cgaacgcgat gactggacga tggccgacct cgtctccaac aggctcggca agttcgtcgc
     5881 cgacgacggg gccggaccca ttggcgacgc catccgcgcc tgggcgcagg agcgccaccc
     5941 cagcctcgac ccgtcgacgc tcccgccgcg ggcccagttc ttcctggaga agttcctcga
     6001 cgcggagatc gccatcgagg tcaagaacat cacctcggcg accggcatcc ccagcttcca
     6061 ggccgtggtg tcggagtacg tcgccgactc gttctcccgt tcccaccacg gcatcggcac
     6121 gcacccggac gccgaggtcg cggtcgtgcg ggccatcagc gaggtcgccc agtcccgtgt
     6181 ggtggacatc caggccatgc gcgaggacat caccgccgcc ggacagcccg tggagaaggc
     6241 tctgtaccac gtgcggcgca gcaaccgcgc gaaccccgac tcgtgggcga tcaagccctc
     6301 cgccagcgcc gtgcgcttcc aggacgtccc gtcccatccg agcacggacg tcatggacga
     6361 cgtccggctg ctgttgcagc gcctgcgggc ccgcggactc gaccaggcca tcgtcgtcga
     6421 cctgtcggcg cccggcgtac ccgccacggt cgtacgcgtc atcgttcccg gcatcgagtc
     6481 gtggaccgtc gaccgcaaca agctcgggcc ccgagccact caggcgtgga acagcgccct
     6541 ggcagccatc cactccgctc agcaacggct gcggacagca ggttccgccc agtgacggga
     6601 gaagagacca tgcgtacggt tgtgttcgtc ggacccagcc tgccgcccga agaggcggcg
     6661 gcccatctgc ccggcgccga gttcctgccc cccatcgagc ggggtgacat cgacgccttg
     6721 atggcggaag agcaaccacc acggcgcatc ggcatcatcg acggaaagtt cctccagagc
     6781 ttctcgatct cccccaagga ggtcttgcgg gccatggatc ggggcgtccg cgtctacggc
     6841 tcctccagca tgggagccct ccgggccgcc gaactcgatg tctacggcat gaccggcgtc
     6901 ggcaccgtct acgccatgta cgcctccggc gcgctggaag acgacgacga ggtcgccatc
     6961 accttcgacg acgagtcgct gcgcccggtg tgcgaaccca tggtcaacat acgggtcgcg
     7021 atggaggcgg cgcagcgccg gagcgtggtg agccaggaga acgcggagtt gttcctgaag
     7081 accgccaagt ccctgtactt cccgcagcgc accagttccg ccgccctgca ccagttgaag
     7141 ggcatcatgc ccgaacccga ccgacagcgc ctcgccgact acctgcggtc gcccgacgcc
     7201 cccgacgcca aacgggacga tgccgtctcg ttgctcgcca ggatgcgaca ggacgccgaa
     7261 gcgtacgacg ccgggcctgc gccggaggtg gcactctgat ggccacgatc gcccctgacc
     7321 tggcagaacg gttccgcacg gacgggttcg ctttccccgt gaacgccctc acgcgggccg
     7381 aggccgaaca ggcgctggcc gagtgccacg cctacctgcg gacggtgagc gccgcaggcg
     7441 gtgccctggc acggtacgcc accttcccga agatccatct ggtgtccacc tgggccgatc
     7501 ggatcgtgca ccatcccgcg atcctcgacg cggccgaagc cctcctcgga cccgacctcc
     7561 tggtctggtc caccaacctc ttcgtccggc ccgcgcgcag cggaagttcg ctcgcatggc
     7621 accaggacgc cgtctatctg gggctgaacg gattccagca gcacgcggcg cgggtctggg
     7681 tcgccctcac cgacaccacg gtcgccaacg gcaccatgcg ctacgcccgt ggctcgcacc
     7741 tcggcggagc actgccccac cggttcagcg gttccgagct tgaggacatc atgcgcggtg
     7801 aggaaatcgc cgtcgacatc gacgaggagg cggccgtcga tgtgatcctc aacgccggcc
     7861 agtgctccgt gcaccacctg gccatggccc actgttcggg ccccaaccac accgccaacg
     7921 gacggttcaa cctcgcgatc gacttcgtcg gcccgcaggt ttctccgacc acgggtgagg
     7981 acagcgcact gctggtacgc ggcacggaca ccggcgcctt cctccccgag agcaggcccg
     8041 cagccgactt cgacggggcc gccttgtcgc agttctatgc cgccgtcgcc cgccgtcaga
     8101 agcggatcga ccaggtggtg ctgcatcgga acggcgagga cggcggcggc gcaggtcgga
     8161 tacgtgaccg ggcatgacga aagcgggaac gaccggcaag gacgccaccc cgggccccgc
     8221 cgccgatggc acctggctgt cccggatcgt ccccccgtgg tggacgagcg gacgcactcc
     8281 tgagcacatg gacctgtcca gctggatgcc ccccgtcatc gaccagggtc aggttccgct
     8341 gtgcaccgct gcggtgacga cggcgatcgc cgggtactac gcccggcggt ccgagcacac
     8401 ggagttcacc gcctccgtct tgttcaacta ccgtctctcc cgtgtgcttg caggctccgc
     8461 cgagcgcaag gggtcccggc tggagcacag ctttcgcgct tgggcggaat ccgggttgtg
     8521 tgaggaagcg gcctggccgt atgacgagca cggcctgagc agggtcgacc gggacccacc
     8581 cgagcactgc cacaccacgg ccaggcgcac cgaacccgtc gcgcaggtcc tctccgcccc
     8641 ggacggagtc ggcctgctgg agctggcccg ccgcgcaatc gcgctcggcc tccccgtgag
     8701 cgtggagatc cgactctgcc cctcgatctc catgtccctg gtcaacggcg gcatcgttcc
     8761 cgtccagctc acgacggagc agtccgtggg accccatgtg gtcctgctga ccggctacga
     8821 cgatcgagct gacaccgctc cgtacgaccg cggtaccgga ccgggggcct tccgggtccg
     8881 caacagctgg gggaccggct ggggcaccaa gggatacggt ctgctgccgt acgccttctt
     8941 cgagcagcag ttgacgggcg agagctgggt cgtcgtcgaa cgggactggc agaaacagtg
     9001 acgtccgccc ctcgcggatc gtcctctcgg cgggtgactg cgcgcgatcg aaccagccag
     9061 tggaggactc ccgggacctt tgtggtgaag agaggactgg gatgatcatc agggtggcga
     9121 gcacccttgc acggaaaggt gattgacgtt gcgaaagttc ctggtggccg ctgcccgctg
     9181 ggcggcgccg accgtcgtcc tcgctcaggt ctgtctcgtc tggaccggtg tgttcagcct
     9241 gggcgaggcc gtggcggtgg ggctggccct tgaactcctc cttgccggga tcgtcatcac
     9301 cgaaatcacc ctcgccagac gggccttcaa ggcgtccagg agccagggcg ccgacgggca
     9361 ggaggccctc aaccaggcgc tttccgcagt cctccccggg cccgtggcca aagccatggg
     9421 gatggaattc ggacttttcc gggccctttg gcgctggatg cgtcgcaagc cggacgcgcc
     9481 ggaggatcac gcgatcctga cctacggctc cgaaatcaag ccaatcatgt gggtgatggt
     9541 cttcctcgta ccgctggaga tccttgccgt cgaattcttg gtgccctggc cagtggtgcg
     9601 catcaccctg ctgattctct ccgtgtacgg aacggtgtgg gtgctcggct tcatcgccgc
     9661 gctctccatc cgcccccaca ccatcggcga cgggaaaatg gtcctgcgct tcgcgcactt
     9721 cacccagatc gtggtcccgc tcgaactggt ggaatcggtg agtacggctc ggcacagcgg
     9781 ctaccgcaga gcgatccaga tcgatgacgg tgtactggcg atgccgatcg gcgactccac
     9841 caccctcagc gtcaagctgc gcgagcccta ccccttggct cccaagcccg ggcagcccgt
     9901 gcaagaagtg cacgaagtcc gcttcgccgc ggacaacact cgcgaagccg tccgcgtcct
     9961 cacggcgagc atcgccgacg cctga
//
