BGC0001699: nidulanin A biosynthetic gene cluster from Aspergillus nidulans FGSC A4
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1,017,270 - 1,047,696 nt. (total: 30,427 nt).
This entry is originally from NCBI GenBank BN001308.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001699
Short description nidulanin A biosynthetic gene cluster from Aspergillus nidulans FGSC A4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
BN001308.1
1017270 - 1047696
via
Compounds
  • nidulanin A
Species Aspergillus nidulans FGSC A4 [taxonomy]
References
Chemical products information
nidulanin A Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ANIA_01243
  • CBF87867.1
1017270 - 1019202 (+) MFS multidrug transporter, putative (AFU_orthologue; AFUA_1G10370)
    copy AA seq
    copy Nt seq
    • ANIA_01242
    • CBF87869.1
    1019461 - 1038626 (-) nonribosomal peptide synthase, putative (Eurofung)
      copy AA seq
      copy Nt seq
      • ANIA_01241
      • CBF87870.1
      1042518 - 1043304 (+) conserved hypothetical protein
        copy AA seq
        copy Nt seq
        • ANIA_01240
        • CBF87872.1
        1043663 - 1047696 (+) ABC multidrug transporter (Eurofung)
          copy AA seq
          copy Nt seq
          Biosynthesis information

          Biosynthetic modules

          Name
          Unk01
          Type
          nrps-type1
          Genes
          ANIA_01242
          Substrates
          phenylalanine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk02
          Type
          nrps-type1
          Genes
          ANIA_01242
          Substrates
          kynurenine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk03
          Type
          nrps-type1
          Genes
          ANIA_01242
          Substrates
          valine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Name
          Unk04
          Type
          nrps-type1
          Genes
          ANIA_01242
          Substrates
          valine (evidence: Structure-based inference [1])
          Integrated Monomers
          Domains
          adenylation
          Annotation changelog

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          Fix biosynthetic class
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Added NRP substrate specificities
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          Submitted
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Detailed domain annotation
          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
          A domain glossary is available here, and an explanation of the visualisation is available here.
          Selected features only
          Show module domains
          Similar known gene clusters from MIBiG 4.0
          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
          Click on reference genes to show details of similarities to genes within the current region.
          Click on an accession to open that entry in the MiBIG database.