BGC0001705: nodularin biosynthetic gene cluster from Nostoc sp. CENA543
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Location: 1 - 48,240 nt. (total: 48,240 nt).
This entry is originally from NCBI GenBank MF668122.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001705
Short description nodularin biosynthetic gene cluster from Nostoc sp. CENA543
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: MF668122.1
Compounds
  • nodularin
Species Nostoc sp. CENA543 [taxonomy]
References
Chemical products information
nodularin
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C41H60N8O10
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATP76236.1
  • ndaI
 1 - 1821 (-) NdaI
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  • ATP76237.1
  • ndaH
 2222 - 3232 (-) NdaH
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  • ATP76238.1
  • ndaG
 3244 - 4041 (-) NdaG
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  • ATP76239.1
  • ndaF
 4083 - 14534 (-) NdaF
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  • ATP76240.1
  • ndaE
 14571 - 15500 (-) NdaE
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  • ATP76241.1
  • ndaD
 15563 - 27274 (-) NdaD
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  • ATP76242.1
  • ndaC
 27314 - 35272 (-) NdaC
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  • ATP76243.1
  • ndaA
 36499 - 44382 (+) NdaA
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  • ATP76244.1
  • ndaB
 44386 - 48240 (+) NdaB
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ndaF
Module ?
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
  • Mass spectrometry
ndaA
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
  • Mass spectrometry
Module ?
Specificity: 3R-methyl-D-aspartic acid branched
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
  • Mass spectrometry
ndaB
Module ?
Specificity: arginine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
  • Mass spectrometry
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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