LOCUS       BGC0001707             27246 bp    DNA     linear   BCT 20-MAY-2017
DEFINITION  Streptomyces sp. strain SCSIO 1682 molecular chaperone GroES,
            mobilization protein, LSU ribosomal protein L11P, and transposase
            genes, complete cds; nosiheptide biosynthetic gene cluster, complete
            sequence; and serine/threonine protein kinase, hypothetical protein,
            transposase, serine/threonine protein kinase, and transposase genes,
            complete cds.
ACCESSION   BGC0001707
VERSION     BGC0001707
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 03:44:22
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..300)
                     /codon_start=1
                     /note="ORF1"
                     /product="molecular chaperone GroES"
                     /protein_id="AQM75222.1"
                     /transl_table=11
                     /translation="MINWIPACGRCEDCRNRQVHLCMGFMENLFSKHRFEIDGTPARQL
                     DGTVETWLLLMRSSVSTRCRPRQRVSRLCAHATRCLRPRTTRTSPTASSTTWRL"
     source          1..27246
                     /db_xref="taxon:1931"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp."
                     /strain="SCSIO 1682"
     protocluster    1..27246
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4148:22985]"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4149..22985
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
     cand_cluster    1..27246
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /kind="single"
                     /product="thiopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..27246
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001707"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..27246
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="thiopeptide"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and ((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or PF07366 or PF06968 or PF04055) or thiostrepton)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             complement(297..875)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF2"
                     /product="mobilization protein"
                     /protein_id="AQM75223.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-15, bitscore: 47.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLVAACFSTGESHREGWPTLVSEDSLGVVRDGSADITGQCAAVL
                     LPQLSALQLGEGGSERVISRGLEMLEGSAGGVGLVSVAFRLVPAPGENRRPDHGREQGS
                     EGAAIRASGSVDDVASCDAYGVGGPVFGPGPEEVKIRIRATGVCHSDLSLISGELPGGG
                     GAMIVGHEGAGEVVEVGDQVTAVAPVITW"
     CDS             complement(2358..2804)
                     /codon_start=1
                     /note="ORF3"
                     /product="LSU ribosomal protein L11P"
                     /protein_id="AQM75224.1"
                     /transl_table=11
                     /translation="MPTQPQPKKKQKINATVRVQQPAGNANVAKIGQVLGAYGVNIAGV
                     MKEFNAATAMHSGLEVSADVIIFEDRSFKLAVKTPTASGLLRQAAGIQKGSSRPHAEQV
                     GTITREQLRKIATIKLPDLNTDSMGEAERIVAGSARSMGIKVVD"
     CDS             2983..4077
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229:transposase
                     (Score: 464.5; E-value: 2.8e-141)"
                     /gene_kind="other"
                     /note="ORF4"
                     /product="transposase"
                     /protein_id="AQM75225.1"
                     /transl_table=11
                     /translation="MPGPKPLPLELSDRERGVLRGWLRKRTAGQALVLRARIVLACAEG
                     RPNAQVAQELGISRETVRKWRSRFAADRLEGLVDAPRSGAPRRITDEQVESLVARTLDQ
                     APPSGDSHWSTRSMAQAAGMSQSAVSRIWRAFGLKPHIVQTWKPSTDPQFVTKVRDVVG
                     IYLSPPENALVLAVDEKSQIQALDRTQPVLPPAPTTPARMTHDYVRHGTTSLFAALDIA
                     SGSVKARHYRRHRHQEFLRFLKTIDDAVPKDLDLDLHLVLDNYATHKTEAVKKWLLRHP
                     RFHLHFTPTSASWLNLVERWFAELTCRNLRRSAHRSVVEPERDIRRRINEWNKNPKPFV
                     WTKTADEILETLAAYCTRTTDSGH"
     CDS             complement(4149..5249)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /note="thiopeptide-type acteriocin biosynthesis domain
                     protein"
                     /product="NosO"
                     /protein_id="AQM75226.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6e-10, bitscore:
                     29.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRSGTDAAPAAENVPLEPDPTDDWLEIRLTGTAPDRDRLLREV
                     ARPLLTSMAPDRPGFFLPAPGTAPSIAALCVQLRPETEEESRACLSQARERARAIGGIE
                     VTAGPARLVPLAGSVFAGPRLGPVTRSVLASACPALLELTVAAERGRPALLWAATELMA
                     AHLRGVSTAGPATVQQLMEGREGVPLGFLSYRSHAEAFVASSRDPQGAQAMLEQKYERV
                     APRVEPLVEGVLAQAEGRGPVVSPAAATWFQAVHPVKAEVTEDFRAGRLRLQDEGPDPA
                     NVGNLKESSFHRVVAGSDGLQRFLNEDPTFLATRLLTSLLYVGLQAGGIALAERYFLCY
                     AVSRACEALFGVNALAVVTALARGTG"
     misc_feature    4149..22985
                     /note="nosiheptide biosynthetic gene cluster"
     CDS             complement(5246..6415)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 76.2; E-value: 3.5e-23)"
                     /gene_kind="biosynthetic"
                     /note="S-AdoMet-dependent oxidase or methyl transferase"
                     /product="NosN"
                     /protein_id="AQM75227.1"
                     /sec_met_domain="PF04055 (E-value: 1.1e-18, bitscore: 58.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYVHVPFCHSRCTFCDWVQAIPNKDLLRRPEDSVRRSYIDAMCR
                     EIKARGAELSRETHTPYVMYWGGGTASSLDEREATQIMEALRSSFDFDGIAEATIECSP
                     DTVDAAKLRFFRSLGFNRVSSGVQSFDNARLRRLGRRHSAEQAEHIVYNAREAGFEDVT
                     IDIMSGFPDQDAEELDATVAKALELPLSHLSLYSFRPTPGTFMRRKMAQAEKRDYLRKQ
                     QLLFTRARQAIHGSGLTEYASGYFGKVSPFAAMYFQLRADTVGLGSGAISLLDGRFQSH
                     KKGLLHSYISDPLGFDIDVPAGQDRVLVSLLQAGLAMFDGVLRDQWRLTSGTELAEVLT
                     RPAIAPLSEFLRGRGLVEDERGIRLPRKQAGITLIELAFEMAMSQPELE"
     CDS             complement(6619..6768)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thiostrepton"
                     /gene_functions="biosynthetic-additional (thiopeptides)
                     predicted thiopeptide"
                     /gene_kind="biosynthetic"
                     /note="putative Nosiheptide precursor"
                     /product="NosM"
                     /protein_id="AQM75228.1"
                     /sec_met_domain="thiostrepton (E-value: 4.1e-17, bitscore:
                     52.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAELNGLDIDALEISEFLDENRLEDSEVVAKVMSASCTTCECCC
                     SCSS"
     CDS_motif       complement(6661..6768)
                     /prepeptide="leader"
                     /note="peptide class: thiopeptide"
                     /note="predicted sequence:
                     MDAELNGLDIDALEISEFLDENRLEDSEVVAKVMSA"
                     /locus_tag="AQM75228.1_thiopeptide"
                     /aSTool="thiopeptides"
                     /tool="antismash"
     CDS_motif       complement(6619..6660)
                     /prepeptide="core"
                     /locus_tag="AQM75228.1_thiopeptide"
                     /peptide="thiopeptide"
                     /predicted_class="Type I"
                     /score="10.70"
                     /molecular_weight="1316.5"
                     /monoisotopic_mass="1315.3"
                     /core_sequence="SCTTCECCCSCSS"
                     /aSTool="thiopeptides"
                     /tool="antismash"
                     /leader_sequence="MDAELNGLDIDALEISEFLDENRLEDSEVVAKVMSA"
                     /leader_location="[6660:6768](-)"
                     /alternative_weights="1334.5"
                     /alternative_weights="1352.5"
                     /alternative_weights="1370.6"
                     /alternative_weights="1388.6"
                     /alternative_weights="1406.6"
                     /alternative_weights="1424.6"
     CDS             7119..8312
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: PF06968"
                     /gene_kind="biosynthetic"
                     /note="Radical S-AdoMet: Biotin and thiamine synthesis
                     associate"
                     /product="NosL"
                     /protein_id="AQM75229.1"
                     /sec_met_domain="PF06968 (E-value: 5.8e-12, bitscore: 36.3,
                     seeds: 824, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQEQADSGGFTLPALAEVREEAATVDTRSVLSLPLGQEPPASR
                     AAVALALWEDRSITTEELKKAAEARCATRAPVLHTFVPLYTTNHCDSECKMCSMRKGNV
                     RLDRKFSGRNEIIEQLRILRDHEGVRGVGLLTGEYEDKHTRLASAFRIGWAIRTALDLG
                     FERVYFNIGSMEPDEIDILGEWVERKDPVTMCVFQESYDRDTYRRFMGKTSAGVPKADF
                     DRRVVSFDRWLDSGYRYVNPGVLVGLHDDLSAELVALVAHGEHLHRRGAVVDLSVPRMR
                     PAMKSRDTTRVGDEDYLRMMAAVAFACPEQRLVLTTREPQEFQDRALGLAGVISPGSPD
                     VAPYSIDAQARNDERSSQFQVADLRRPRHILDRIESSGIEVGHFVNPSPRPAAVGRS"
     CDS             8648..9019
                     /codon_start=1
                     /note="fold family hydrolase/acyltransferase"
                     /product="NosK"
                     /protein_id="AQM75230.1"
                     /transl_table=11
                     /translation="MQIAGFERLAAQHPELAGEYERLHSVRWKQTLDSVVDHVGRDFAG
                     TVRVSPQELTELGIRTLLINGSLKSAERAAAESAARLGGPVSGHVVPGAGHLVSQDAPE
                     QFIQAVESFWHGETDHDFT"
     CDS             9389..10525
                     /NRPS_PKS="Domain: AMP-binding (48-289). E-value: 3.2e-30.
                     Score: 96.8. Matches aSDomain:
                     nrpspksdomains_AQM75231.1_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     126.1; E-value: 2.3e-38)"
                     /gene_kind="biosynthetic-additional"
                     /note="AMP-dependent acyl-CoA synthetase/ligase"
                     /product="NosI"
                     /protein_id="AQM75231.1"
                     /sec_met_domain="AMP-binding (E-value: 3.9e-31, bitscore:
                     98.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASLASLLAVASVPETVLLWASPKRLGLTVQESAPEVFEVTGGAA
                     LLAPSERPLWGICTSGSTGTPKVAIGHADEWELIALHSEAAVYQDAIGGRPPTALATCL
                     PLGFSAAFFMSVLPALFFRRDLLIFPPHDWRPLIGLAQRHRVAALGVPALAAAACINAT
                     EPEAMDSVALFLGGGHLSGERVRLIRERFTGIRVSNLYGTAETGAIALDHDPGHNEHVG
                     FPIAGKSVWIRDPDERGTGEVCVTGPGCAQYQWRPGQPPAPTAGLVSGTDYGRFDTAGH
                     LCLEGRPDGGEKLAGVLVYPRAIERHLLSMDGVSDARVTVEHPASGLEHLAATVVGEVD
                     PSAVEEHCTQLPEHLRPSRIRCVSEREVASVYTAHGKL"
     aSDomain        9533..10255
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQM75231.1_AMP-binding.1"
                     /evalue="3.20E-30"
                     /label="AQM75231.1_AMP-binding.1"
                     /locus_tag="AQM75231.1"
                     /protein_end="289"
                     /protein_start="48"
                     /score="96.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="PSERPLWGICTSGSTGTPKVAIGHADEWELIALHSEAAVYQDAIG
                     GRPPTALATCLPLGFSAAFFMSVLPALFFRRDLLIFPPHDWRPLIGLAQRHRVAALGVP
                     ALAAAACINATEPEAMDSVALFLGGGHLSGERVRLIRERFTGIRVSNLYGTAETGAIAL
                     DHDPGHNEHVGFPIAGKSVWIRDPDERGTGEVCVTGPGCAQYQWRPGQPPAPTAGLVSG
                     TDYGRFDTAGHLCLEGRPD"
     CDS_motif       9557..9592
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQM75231.1_0001"
                     /evalue="4.20E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="AQM75231.1"
                     /protein_end="68"
                     /protein_start="56"
                     /score="13.3"
                     /tool="antismash"
                     /translation="ICTSGSTGTPKV"
     CDS             11055..12497
                     /codon_start=1
                     /note="hypothetical protein"
                     /product="NosH"
                     /protein_id="AQM75232.1"
                     /transl_table=11
                     /translation="MEQSAQVPDSGHRWRLHSTDGGPLEGLGDHPVCADADAVLLACDD
                     AAPAALGQVQRLLRSRGIPVGVLGRCGPFTTAVPPMAEAAWCWECVYRSIGVPANGDAA
                     GLALSAAPATVGALRLAQQVFALLADVRMPDAESVTTVEPLAPVVRHHTVHRHPCCPHH
                     GHEVAATAQPAPAASGDEDGSGEAAVPETAVRPDIPMPEDPPERVAVSDRIVAAAAGLT
                     DSLTGPLLALGEDDLSQLPLSASSCRVVHPAGDADRPAALRVICRALSPREARNQAVLF
                     AMERLATQVAELNWSAERNAARYRFGAGWSLAEARFRARLHVALDAPAGRPHEAAGPEE
                     RPADGTVLAFLAQTLAGLGAGARWRAGELEKPAHGAIRARITTADGATATGVGTHRDQA
                     LAHALARAVAARTPSGAGPQDLEHVAFLAPPVRTWAQTEAAGLAAHEVTELLPFLRPAR
                     GGGSGGGATLRVVALAPEEVSR"
     CDS             12683..14452
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_kind="biosynthetic"
                     /note="cyclodehydratase"
                     /product="NosG"
                     /protein_id="AQM75233.1"
                     /sec_met_domain="TIGR03604 (E-value: 2.3e-94, bitscore:
                     306.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 5.7e-69, bitscore: 223.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVESLVMGRRLLFVGTWRSLAYLGPLWTPGTQGCPRCLVTRTANT
                     PFGPGLDGDDLAESLPHAPDVRTWGPGVLGIIEHYVRALLSTDTAPGDTATDRWVVVVD
                     GTAGSVEHQPLLADSICPGCGAISTDTLPELTPREVPVTKPDPAVLRTGRLDPDRLCRQ
                     LLFPGLGLFKEVRQDLQSPFGACSVELPSRWGRREPAIGRARDYRSSRAIAVLEGLERY
                     AGLQRGGRAAPVRASYADVADRALYPPSLGTHPPESHQIEGFRYQQFHPDTVIDWVPAY
                     SFQQDGPVLVPERAAFWGPRHDGEISFFYDTSNGCALGSCTEEAVLHGLRELAERDAFL
                     LTWYRRLALPEVQLEGADAGLDQLLAKSGLFTGFRFRCFNASMEYGMPTFVLTAESSRD
                     DGPRMFAGGSAHPDPVQAVTGGLHELVGTILATRDSYQRNRGAALQMLAEPDLMRRMED
                     HSAVGALPEARDRYAFLLNRPAPAEGLLPLAEIPGTLRSDQDDLRADLHIALAGVLDEG
                     MDVLVVDQTMPELRRNGVCCVRVLVPGLLPMTFGHRNRRTAGLPRLTEGTSLPYAAQPD
                     PDAPIGAVPHPFP"
     CDS             14896..16089
                     /codon_start=1
                     /note="dehydrogenase"
                     /product="NosF"
                     /protein_id="AQM75234.1"
                     /transl_table=11
                     /translation="MVPAEEDLVHHYCPYRHELVCLGRTGAAALLRRTLGFAEDEPAGH
                     LVVLTTRFWKSFYKYGDFTARLAAVDAGVVLGGVLRLAEAEPGPTRLRTGFPGAAVAEC
                     LGIATTEDAPWAVLGFGPPAGPRGAASPASVPAPPRALERSRRVKRSAAFDRLQRACQE
                     PAVPPASVADGGPPPPPPLKPVPLAAPRCTALLDLAVRARRASRGARFTGAEVECAALA
                     AVLHTAADALNRLARTGSGPAAHWAAHTRLHCAVHRVSGVAPDWYRYQPEAQALLRTGA
                     DADPRCAVTVRKALFAASFNPELAAFTVHVSTPLDWRAWRGPVAYREQQLAVGAAVEAI
                     TLAAATERLSGHPVLGFDADLIDRAYRLVDSGHGVQAQICVGAVRTDPQWEMGISQR"
     CDS             17394..18842
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /note="dehydratase"
                     /product="NosE"
                     /protein_id="AQM75235.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.5e-29, bitscore:
                     91.0, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSVLFEDVGTWEPPHDDPTALFDGDRASLELFQRIVPVLDDASI
                     EKAGLYTYFTRLYGGDERPVPAIEFYRAFAELAPNDAAAVATGQGDAHCDWLRELRTEL
                     LDELRAAAGRDGEVWLDAARLRAFADRLPASLPPWRSAAYRVQIATEAGERLAVVNGVT
                     TGQGVFFSRFCELLETTGPEGWSLTGALRWWIPRNAPRQTDLTAVLGLNFNLHPRLSPH
                     ELVYPGSIARRGPSEPLTLADLYVRADHRRRRLQLVSARDGEPVDLVPLNFLYPAAAPG
                     LYRFLCAFAPTRTYRGGLWEQLARADARSGRAVSPGPQRRPRVRLGGLVLDRASWSFPA
                     RDVPEPAGGGEWDTEVLARFDRWRREHGVPRHCFFQLISAPPPGDGSGDGLEEARQWAL
                     QARSARLHKPHYLDSRNPFLLQVLARQLTEAADGTVIFHECLPSPADTLAAHPPRSAEE
                     FFVEYTLSSRPSRPHVMEDHRVRD"
     misc_feature    18048..18050
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             18772..19848
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /note="dehydratase"
                     /product="NosD"
                     /protein_id="AQM75236.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.2e-56, bitscore:
                     181.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWSTRFPPAPPARMLWRITVSGTEAAAWQSLHIHRYEDQDGFLVD
                     GLDPVLTPLRASGAVEEFFFLRYWQGGHHIRLRLRTSLKTAQEVADALAAYLARHPAGT
                     GFDAEEFGPAQATMAVLEAETTSEVLPPDSVHHATYTPEVEKYGGNLGVAIAERFFAAS
                     SDVALATLARLPGGSGKRLGAAFSTMLHGLCAARLTPAEMAGFFAHYCVLWSPYVFDRF
                     LADWPELLRVRREPVGRHAATLLAQSHQEPADPFGRAVGTAWRELAESADTVLPAVTLG
                     GSDAPVARRRQILLVSYLHTHNNRLGLIPEQESFLGWLGHHVMSEYAGLPPAADLLDRV
                     RVTRRERLGAYADLAPTS"
     misc_feature    18814..18816
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             19874..21232
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 387.1; E-value:
                     1.5e-117)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450-like enzyme"
                     /product="NosC"
                     /protein_id="AQM75237.1"
                     /sec_met_domain="p450 (E-value: 1e-29, bitscore: 94.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHCARFARSVLARSAWDAAACSTKIRRPGPGTPSSARPRGEFMD
                     VTDRTYPFARHCPFAMPEEFGWLRGRQPVAKVRLESGDEAWLITRYEDVRAALTDPRFS
                     RSIHRDGAARVDTGFQADADSPLFNFGGTISEPPGHTRWRRIVNRAFTSRQAESMRKEI
                     AAHTDALLGELAARGEGFDLMADFAYRLPITVICDLLGLEDAARPEFTELAAQLTRRDM
                     QSSFIEFGQALQAIGRYAVGLIVRKRKNLGDDLLSTLITLRDEEGDAEGLTNEELVSTV
                     ILLLMAGYESTAVQLGNAFYALLRDPDQMRALREHPERIDHAVEELLRYAQMGTGYAIA
                     KFTTADVEMSGVTIPAGSTVFVSLASANRDERIFGTDADTLDLNRAEARRQTAFGYGPH
                     YCLGAALARVEMQEAVARTLARFPGLHHDGDLDAVELNSNLFTYYPRELRVLP"
     CDS             21265..22488
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 335.6; E-value:
                     6.6e-102)"
                     /gene_kind="biosynthetic-additional"
                     /note="transposase cytochrome P450"
                     /product="NosB"
                     /protein_id="AQM75238.1"
                     /sec_met_domain="p450 (E-value: 1.2e-17, bitscore: 54.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIAQEADAYPFPLTCPFTQPPELARRRNEAPIAPVTLPGGAPAW
                     LVTRFDDVRTVLTDERFSRSPVRQNAVREQHRAGPAPGPGQFDFGAQLADPATHARWRS
                     RLGSVLTPQHAESLRPRIGQIVDAALDEIAARPDHTAEFVSDFAYRIPVQVLAGLFDLT
                     PQLCDRLQDWATRLRGAAPSTAAFGEAMRSLYGVAAELVARERAEPGPGVIGLLLSADR
                     EGAETMTDEELVSTVFLLATAGYESTAVQFANGLLALFQHPAKLERLRSGSVSMATAVE
                     EILRYAQAGTGFAGTTYTTEEVRLGEVALPAGATVLISLDSAGRDERRTDRPEVFDPSR
                     GAPHHHLTFGAGGHFCLGAAVARVELQEGFTRLLARFPGLRPSGDPWKTEFTRNLFHHY
                     PRELRVEW"
     CDS             22485..22985
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thio_amide"
                     /gene_kind="biosynthetic"
                     /note="hypothetical protein"
                     /product="NosA"
                     /protein_id="AQM75239.1"
                     /sec_met_domain="thio_amide (E-value: 1.7e-33, bitscore:
                     105.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGHREEVDMSDQAPSLYCSIILWDLSRSSQTVRSLRAYLRDYAV
                     DSYEKMPGLRQKVWISSTGPEGELWGAVYLWDSQEAAYGRPPGVSHVVELIGYRPTERR
                     YFGVEAAATGLDSLVGALTAGVGMAFQPGSPEPSARPQEFVPPGADTFIPAGANPGSGP
                     PVS"
     CDS             complement(22978..23442)
                     /codon_start=1
                     /note="ORF5"
                     /product="serine/threonine protein kinase"
                     /protein_id="AQM75240.1"
                     /transl_table=11
                     /translation="MTGQSDADGVTGGCARCGPAYLELLALSYNAPERQPHHQLLVDSY
                     SVQHPGGEDPVATQRLSICLMTLYLFLERGADPQHGPQLHRRMVHRARFTRLEPHPSAQ
                     DLHKKLTAADVAAADATEYGKQLRAWAGDVWDAWREHHAQVRAWTDASLS"
     CDS             complement(23505..24047)
                     /codon_start=1
                     /note="ORF6"
                     /product="hypothetical protein"
                     /protein_id="AQM75241.1"
                     /transl_table=11
                     /translation="MKDCRWSPHDAAACPGCGLVGEGDASGPVHAYMSTEAVCWGLFCR
                     LLAELGPEATRLATDAYAAQHPLGGEDDRRQRQSVAVHLMALCLHVENRVREERLRRMM
                     TSLSRSVLPRLKMPEWPALAPPSDLGQITVRDVDRAAPEERHQVIEEWAWSVWAAWAEQ
                     HDTVRGWAALALSADRR"
     CDS             complement(24665..25129)
                     /codon_start=1
                     /note="ORF7"
                     /product="transposase"
                     /protein_id="AQM75242.1"
                     /transl_table=11
                     /translation="MLAAHPAPVDRASSGLGSPFNARMWEPSTAAREKSRAFALRSLAR
                     RNSCSRGHTPASVHSARRRQQVMPEPKPSSCGRCSQEIPVCRTNRMPWNTSRSGCRLRP
                     GCRTRRSTLGNSGSITAHNSSSTSHGFGRATPHPRINVPGVIQPPRRSFR"
     CDS             complement(25534..25986)
                     /codon_start=1
                     /note="ORF8"
                     /product="serine/threonine protein kinase"
                     /protein_id="AQM75243.1"
                     /transl_table=11
                     /translation="MDLISLSDGDNGFRVRVLGRRSPGVLHLHDQLDAEVLITSSFVSG
                     RLGMSLFPSDLEDWSRALDLLAAGQDICWRDDDHSPEIRIQPHNEEHETPAVHVEDPGS
                     SCVSVFLPMRLEEGWVDEQRRLLGRVLKEWPSEVLQSSPGVYEWRR"
     CDS             26332..27246
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097:transposase
                     (Score: 212.2; E-value: 1.3e-64)"
                     /gene_kind="other"
                     /note="ORF9"
                     /product="transposase"
                     /protein_id="AQM75244.1"
                     /transl_table=11
                     /translation="MLYASEPVQFNSAAPSCDCLAHVYGNAADHPDRERRYPSDMTDAE
                     WAAVRPLLPVPAWLKGRGGQPEGYCHRQLLDAIRYLVAGGISWRAMPADFPDWGRVYAF
                     FRRWREHGLITEFHDRLRGRVREREGREAEPTAGIIDAQSVKAAASVPSVSRGYDGGKK
                     VGGRKRHIVTDCLGLLLVVAVTAANIGDRDAATGLLTRLRRLHRDICLVWADGGYTGGL
                     VDWCRDKLALTLEIVKRTDDMTGFVVLPRRWVAERTFAWLMHSRRLARDYETLLASSEA
                     MIRWSMVTRMSRRLARPQAAGRH"
ORIGIN
        1 tcagaggcgc catgtcgtcg atgaagctgt cgggctcgtc ctggtcgtcc gggggcgaag
       61 acagcgcgtc gcgtgtgcgc agagtctcga aacgcgctgc cgcggacggc agcgtgtact
      121 gacgctcgac ctcatcagga gtagccacgt ctccaccgtg ccatcaagct gccttgccgg
      181 ggtgccatcg atctcgaaac gatgcttgga gaacaggttc tccatgaatc ccatgcagag
      241 gtgcacctgc ctgttgcggc agtcctcgca tcgtccgcaa gccgggatcc agttgatcac
      301 cacgtgatca ccggggcgac ggcggtgacc tggtcgccca cctcgaccac ctcgcccgcg
      361 ccttcatgtc cgacgatcat cgcaccgcca ccgccgggca gttcaccgga gatgagggag
      421 agatcggagt ggcacacacc ggttgcgcga atgcggatct tgacctcttc ggggccgggg
      481 ccgaagaccg ggccgccgac gccgtacgca tcgcagctcg cgacatcatc gacactgcca
      541 ctggcccgga tggcagcgcc ctcgctgccc tgctcgcggc catggtctgg gcgacgattc
      601 tcgccgggcg ccggcacgag gcgaaaagcc acgctcacca ggccgacgcc gcccgccgaa
      661 ccctccagca tctccaagcc gcggctgatc acgcgctcac tcccaccctc gccgagctgg
      721 agcgccgaca gctgagggag gaggaccgcc gcacactggc cggtgatgtc cgcgctgccg
      781 tcccggacca cgccgagcga atcctcgctg accagagttg gccagccctc gcggtggctc
      841 tcgccagtgc tgaagcaggc ggccacaagg ctcatcagct cctcaaggag gctgccgagc
      901 agcgcgaact gcataccgcc cgtcagcccg ctcgcgttct gatcacccgc atccagcaca
      961 cgagtcgaaa ccccgtgccc aaccgccgag ccgaagcgac ccgtcggtgc tcgaccacat
     1021 gcgcaccggt ggttggcagc gtgaggccgc ctgcacacca gtcgaccgct ccagctcccg
     1081 ctccaggaca accgcccgcg gcgttagctc agtactcggg ggcgtcccag gtgacattga
     1141 cctcgcccag cccttggtcg gagacgagca tggaacgctg gaggcggcgc agcgcgggag
     1201 agggctccag gccgaactcc ttgaccaggc tggagcgcac cttgtggtat acctccagcg
     1261 cctccgagcg tcgtccggcc cggtacagcg cgagcatcag atgcgcgcac agaccctcgt
     1321 gcgtggggtg tcgggcgata atgccccgca gttcgcccag gagctcatgg tggcgtccca
     1381 ggcggagatc cgcatcgata cggcgatcaa ggaggttgag gcgggtctcc tcgagctcta
     1441 cgacctccgc ctggagctgg ggcccggtgc gtatgtcgga gagtgcgtct ccgcgccaga
     1501 gcccgagcgc cttggcgaag gcgtcggagg tggcctggaa gtcgccttgc tcccgggcgc
     1561 ggtagccgac cgccgtgaac atctcaaagc gccgcagcgc cacctcgtcg tcggcgatct
     1621 taagtacata accgtcggac tccgtatcca aggcgagcct gggctcagag tcgacggccg
     1681 ctcgagaccg gtctgcggcc tgggccatgc gcttacgcag atcgaggaca tatgtctgca
     1741 cagcggttcg cgcgtacgct ggggcattct tggcccacag ttcgtggatg atcattgaga
     1801 ccgggacgaa ctgattggcc cgcatggcca gcagcgcgag gagtgctttg gcctttggcg
     1861 ccgtgggaac caccgagctg acgccctgcg aaacctttaa tgggccaagc acatccacgt
     1921 gcatcgcttc ccccgtgatg aagtttggtc accatactgc cgctgtcccc gtacatgcct
     1981 cgggcatact cttccgggaa cacatcagat gcgacgcact gaacgcgccg gccgaacttc
     2041 gcgcccctcc ccgggcgatt cggagagcgg aatcaggatt ccaggtcggc gactcggagg
     2101 accagcaagc gagcgatgtc cgcagggttg gactccgagt cctcggcaac gacagcgacg
     2161 gcaagggcgg cgaaacgcag cattccggta agggcgccag gcgagtccgg aatctgccgc
     2221 agacattctt tcactgccgc ctcatcgttg gccaggaagt gtgacactgc cgcaccggcg
     2281 agctgtgtcg ccctcatatt tcgccgctcc cgctccagcg aactcacgcc ttctcggttc
     2341 gatgccggcc gcccacgtca gtcgaccacc tttataccca tggagcgagc ggagccggcc
     2401 acgatgcgct cagcctcccc catgctgtcc gtgttgaggt cgggaagctt gattgtggcg
     2461 atcttccgga gctgctcgcg cgtgatcgtg ccgacctgct ctgcatgcgg ccgggaactg
     2521 cccttctgaa tccctgcggc ctggcgcagc agaccggagg cggtgggggt cttgacggcc
     2581 agcttgaagg agcggtcttc gaagatgatg acgtcggcgg agacttcgag tccgctgtgc
     2641 attgcggtgg cggcgttgaa ctccttcatc acgccggcaa tgttcacgcc ataggcgcca
     2701 agcacctggc cgatctttgc cacgttcgcg tttcccgcag gctgctggac gcgcacagtt
     2761 gcgttgatct tctgcttctt cttgggctga ggctgtgtag gcacggtggc tccctcgtaa
     2821 taatgtgcga actccgctga gaggctacct gacttatgtg atgcccctgc aggagaccag
     2881 atgttttccg gccggcagaa atggagcact ggattccgga actcttcggc tcctagctag
     2941 tgacctgagt cagcagttcg tttgcggttg tagggttgag ggatgccggg tccgaagccg
     3001 ttgccgttgg agttgtccga ccgcgaacgc ggggtgctgc gaggctggtt gcgcaagcgg
     3061 accgcggggc aggccctggt gctgcgggcg cggatcgtgc tggcgtgcgc cgaggggcgc
     3121 ccgaacgcgc aggtcgcgca agaactcggc atctcgcggg agacagtgcg caagtggcgg
     3181 tcccggttcg ccgccgaccg tcttgagggg ctggtcgacg ctccgcgttc cggagccccg
     3241 cgcaggatca ccgacgagca ggtcgaatcc ctggtcgccc ggacccttga ccaggcgcct
     3301 ccttcggggg attcgcactg gtcgacgcgg tcgatggccc aggctgcggg catgtcgcag
     3361 tcggcggtct cccggatctg gcgggcgttc ggcctcaagc cgcacatcgt gcagacctgg
     3421 aagccgtcca ccgacccgca gttcgtgacc aaggtccgtg acgtggtcgg catctacctg
     3481 tccccgccgg agaacgccct ggtcctggcg gtggacgaga agtcgcagat ccaggctctg
     3541 gaccgcaccc agccggtgct gccgccggca ccgacgacgc cggcgcggat gacgcacgac
     3601 tacgtccggc acggcaccac aagcctgttc gccgccctgg acatcgcctc cggctcggtc
     3661 aaggcccggc actaccgccg ccaccgccac caggagttcc tccgcttcct gaagaccatc
     3721 gacgacgccg tacccaaaga cctggacctg gacctgcacc tggtcctgga caactacgcc
     3781 acccacaaga ccgaagcggt caagaagtgg ctgctccgac accctcgctt ccacctgcac
     3841 ttcaccccca cctccgcctc ctggctcaac ctcgtcgagc gctggttcgc cgagctgacc
     3901 tgccgcaatc tccgccgctc ggcccaccgc agcgtcgtcg agccggagcg ggacatccgc
     3961 cgccggatca acgagtggaa caagaacccc aagccgttcg tgtggaccaa gaccgcagac
     4021 gagatcctcg aaaccctcgc cgcatactgc acacgaacta ccgactcagg acactagcca
     4081 ggagccgtgg aagattaagc aaccaacgcc gctggcgcgg cgtgctctgc atcgcttccg
     4141 ggaagtgctc agcctgtgcc tcgggccagg gccgttacca ctgccagggc attcaccccg
     4201 aagagcgctt cacaggctcg actgaccgcg tagcagagga agtagcgctc ggccagcgcg
     4261 atgccgccgg cctggaggcc gacgtagagc aggctggtca gcaaccgggt ggccaggaag
     4321 gtcggatcct cgttcaagaa gcgttgcagg ccatccgagc cagcgacgac ccgatggaat
     4381 gaactctctt tcagattacc gacattggcc ggatcaggac cctcgtcctg gagccgcagg
     4441 cgccccgcgc ggaagtcctc cgtcacctcg gccttgaccg gatgcacagc ctggaaccag
     4501 gtcgccgcgg ccggggacac cacgggtccg cgaccctcgg cctgtgccag caccccctcg
     4561 accaggggct ccacccgggg agcgacccgc tcgtacttct gctccagcat cgcttgcgcg
     4621 ccctgcgggt cccggctgga cgcgacgaat gcctcggcgt gcgagcggta gctgagaaag
     4681 ccgagaggga cgccttcccg cccctccatg agttgctgta cggtcgccgg ccccgcggta
     4741 ctgacgcccc gcagatgcgc ggccatcagc tccgtcgccg cccacagcag ggcgggcctg
     4801 ccgcgctccg ccgcgacggt cagctccagc agcgccgggc atgccgacgc cagcaccgac
     4861 cgggtaaccg gcccgagccg cggcccggcg aacacggaac cggcgagcgg gaccagccgg
     4921 gccgggccgg ccgtcacctc gatcccgccg atcgcccgcg cacgctcccg tgcctggctc
     4981 aggcaggcgc gggactcctc ttccgtttcc ggccgcagct gcacgcagag agcggcaatg
     5041 ctcggggcgg tccccggggc gggcagaaag aatccgggcc ggtcaggggc catgctggtc
     5101 agtagcgggc gggccacctc ccgcagcagg cggtcccggt cgggcgcggt cccggtcagc
     5161 cggatctcca gccagtcgtc cgtcgggtcc ggctccagag ggacgttctc tgcggccggt
     5221 gcggcgtccg tgccgctgcg cgtggtcatt ccagctccgg ctgggacatg gccatctcga
     5281 aggcgagctc gatcagcgtg atgccggcct gtttccgggg cagccggatg cctcgctcat
     5341 cctcgaccag accccggccg cggaggaact cggagagcgg ggcgatcgcc ggccgggtca
     5401 gcacctcggc cagctctgtg ccggaggtga gccgccactg gtcccgcagt accccgtcga
     5461 acatcgcgag accggcctgg agcagtgaga cgaggacccg gtcctggcca gccggcacat
     5521 cgatgtcgaa gccgagcggg tcactgatat aggagtgcaa cagccccttc ttatgggact
     5581 ggaaccgccc gtccagtagg gagatggcac cggatcccag ccccaccgtg tcggcgcgga
     5641 gctggaagta catcgccgcg aacggcgaga ccttgccgaa gtagcccgag gcgtactcgg
     5701 tgagccccga tccgtggatg gcctgccggg cccgggtgaa gaggagctgc tgcttgcgta
     5761 gatagtcccg cttctccgcc tgggccatct tacgccgcat aaaggtgccg ggtgtcgggc
     5821 ggaaggagta gagcgagagg tggctcagcg gcagctccag cgccttggcc accgtggcgt
     5881 cgagctcctc ggcgtcctgg tcggggaagc ccgacatgat gtcgatggtc acgtcctcaa
     5941 agccggcttc ccgggcgttg tagacgatgt gctcggcctg ctcggcggag tgccggcggc
     6001 cgagccgccg cagcctggcg ttgtcgaagg actgcacgcc gctggagacc cggttgaagc
     6061 ccagcgagcg gaagaagcgc agcttcgccg cgtccacggt gtccgggctg cactcgatcg
     6121 tggcctcggc gatgccgtcg aagtcgaagg aggaccgcag cgcctccatg atctgggtgg
     6181 cctcgcgctc atccagactg ctggccgtgc cacctcccca gtacatcacg tagggggtgt
     6241 gcgtctcgcg ggacagctcc gccccacggg ccttgatctc acggcacatc gcgtcgatgt
     6301 acgagcgccg gacggagtcc tcggggcggc ggagcagatc cttattggga atggcctgga
     6361 cccagtcgca gaaggtgcac cgggaatggc agaacggtac gtgcacatag agcatcacca
     6421 cccgccgttc cggcgtactc aaaggaagcc cggagattga catatctgcg acgagcggtg
     6481 ccgtggaggg catggaaatt cctttcacaa gccgatgtgg cataccagga tcaggagagc
     6541 ggtgtccatg ccggaaaacc ggcgcggaca ccgctccccg cgtgtcagtg cacgctgatc
     6601 acctgatgca ctcctgggtc aggaggagca ggagcagcag cactcgcagg tggtgcagga
     6661 ggccgacatc accttggcga caacctcgct gtcctccagt cggttctcgt ccaaaaattc
     6721 ggaaatctcc agggcgtcga tgtccagccc gttcagctcc gcgtccatgg gaaccctccc
     6781 ttcaatttgg gtcggaataa atgtgcgccg attggctgtg cgcaacacgg aggctatgag
     6841 gaccctttct cgctggtcaa gagtctttga gcgatccgcg agaagcactc ataacccgct
     6901 ttccggatgg cctgtcatca ctccgcgcac actaaggaac gggtgaagag atggcaggca
     6961 gacggtaggg catccactaa ggaacgactc atctttgcag gtggcagccg gaagtggagg
     7021 gatctccgtc atttcgatga cctcttgccc gcggcgattt gccacggata tacatgcggc
     7081 gttcgcacac ttcatctggc acgcagagga gattcgctat gaccgagcag gagcaggcag
     7141 actccggcgg attcaccctt ccggccctgg cggaggtgcg cgaagaagcg gccaccgttg
     7201 acacccggtc ggtcctttca ctcccgctgg gacaggagcc cccggcgtcg cgtgcggccg
     7261 tcgcgctcgc gctgtgggag gaccgctcga taaccaccga ggaacttaag aaggcggccg
     7321 aggcgaggtg tgcgacccgt gctccggtcc tgcacacctt cgtcccgctc tacacgacca
     7381 accactgcga ctccgagtgc aagatgtgct ccatgcggaa gggaaatgtt cgcctcgacc
     7441 gcaagttctc cggccgcaac gagatcatcg agcagctgcg gattctgcgc gaccatgagg
     7501 gtgtgcgcgg ggtcgggctg ctcaccggcg aatacgagga caagcacacc cgcctcgcct
     7561 ccgccttccg catcggctgg gccatccgca ccgcgctgga tctgggcttc gagcgggtct
     7621 acttcaacat cggcagcatg gaaccagacg agatcgacat cctcggggaa tgggtggagc
     7681 gcaaggaccc ggtcaccatg tgcgtcttcc aggagagcta tgaccgggac acctaccgcc
     7741 ggttcatggg caagacgtcc gccggggtgc ctaaggccga tttcgaccgc cgcgtggtct
     7801 ccttcgaccg ctggctcgac tctggctacc gctatgtgaa cccgggcgtg ctggtcgggc
     7861 tgcacgacga cctgtccgcc gagctggtgg ccctggtcgc ccacggcgag cacctgcacc
     7921 ggcgcggggc cgtggtggac ctttccgtgc ctcggatgcg tcccgctatg aaatcgcgcg
     7981 acaccacccg ggtcggtgac gaggactatc tgaggatgat ggcggccgtc gcgttcgcct
     8041 gcccggaaca gcggctcgtt ctcaccaccc gcgagcccca ggagttccag gaccgtgccc
     8101 tcggtttggc cggcgtcatc tcccccggca gcccggacgt ggcgccttac agcatcgatg
     8161 cgcaggcccg caacgatgag cgttcctcgc agttccaggt cgccgacctg cgccgcccac
     8221 ggcacatcct cgaccgcatc gagtcctcgg gcatcgaggt gggacacttc gtcaacccgt
     8281 cgccccggcc cgccgccgta ggccgatcgt gactcagcga ccgctcgtct atctgctcca
     8341 tggcctgctg ggcacagcat atgcgcactt cggccggcag atctccgcat ggcgcgaccg
     8401 gtaccggccg gtggccatcg atctgcccgg ccacggccgg tgcccgctgg atgcccaacc
     8461 cgactactac gacgacgcct tgtgctacgt actggccctg ctcgaccgct tcgggccggg
     8521 acggctgatt ggcgcctcgt acctcggagg cccgctcgcc atacgtgccg ctgccgctcg
     8581 tccgcacctg gtcggctccc tggtgctcac ggggttcgtg ccggacaccg ccgaggacgc
     8641 cttccaggtg cagatcgccg gctttgagcg gctggccgca caacacccgg agctcgcagg
     8701 cgagtacgag cggctgcact cggtgcgctg gaagcagacg ctcgactcgg tcgtcgacca
     8761 cgtaggacgc gactttgcgg gaaccgtgcg cgtgagcccg caggaactga cagagctcgg
     8821 gatccgcacg ctgctgatca acggatcgct caagtccgcc gagcgggccg ccgccgagag
     8881 cgcggcccgc ctgggggggc cggtaagcgg ccatgtcgtg ccgggcgcgg gccacctcgt
     8941 cagccaggac gccccggagc agttcatcca ggccgtcgag tccttctggc acggggagac
     9001 cgaccatgac ttcacctgag ccgccatccc ccggctcgct gcgggacagc ctgtcccggc
     9061 tgctccaaga ggaggatccg caccgcccgc tcgactcgct ggaggtggtc gtggtgcggg
     9121 gcttcttcac ccagcgccta ccgcacctgg atccccccac gcagggggac gtccccaaga
     9181 ccatcgaagg gtgggtgaca tgggccgaac gcccttcagc cgcttcctga cccccgccgt
     9241 ggccggtccc acggccacgg gccgcgaccc cggcgtgtac tggggggagg agttcgcccc
     9301 ctgggacgac ctgctgtccg agggtcgccg acgcgcggcg cggctccgct ccggcgccac
     9361 ctacgtcgtg gacccggaag gcgggccgat ggcgtcgctg gcctcgctgc tcgccgtcgc
     9421 ctcggtcccg gagaccgtgc tgctatgggc gtctccgaag cgcctggggc tcaccgtcca
     9481 ggagtcggct cccgaggtgt tcgaggtgac cgggggagcc gcgctgctgg caccgtccga
     9541 acgccccctg tgggggatct gcacctcggg cagcaccggc acgccgaagg tagccatcgg
     9601 ccacgccgac gagtgggagc tgatcgcgct gcacagcgag gcggcggtgt accaggacgc
     9661 catcgggggc aggcccccca ccgcgctggc cacctgcttg ccgctggggt tctccgccgc
     9721 cttcttcatg tccgtgctgc cggctctctt cttccgtcgc gatctgctga tcttcccgcc
     9781 gcacgactgg cgtccgctga tcggcctggc ccagcgtcac cgggtggccg cgctgggtgt
     9841 ccccgcactc gccgccgccg cgtgcatcaa cgcgaccgag ccggaggcga tggactccgt
     9901 ggcgctgttc ctggggggtg gccatctcag cggtgagcgg gtgcggctca tccgggagcg
     9961 cttcaccggc atccgggtga gcaatctcta cggcaccgca gagacggggg cgatcgcgct
    10021 ggaccacgat cccggacaca acgagcacgt cggattcccg atcgccggga agtccgtgtg
    10081 gatccgggac cccgacgagc ggggcaccgg cgaggtatgc gtcaccgggc ccggctgtgc
    10141 ccagtatcag tggcgccccg ggcagccgcc ggcccccacc gccggcctgg tgtccggaac
    10201 ggactacggc cgcttcgata ctgctggcca cctctgcttg gaagggcgcc cggacggcgg
    10261 cgagaagctc gccggcgtgc tggtgtaccc gcgggccatc gagcgccatc tgctctcaat
    10321 ggacggcgtc agcgacgccc gggtcaccgt ggagcacccg gcctccggac tggagcacct
    10381 ggccgccacc gtggtcgggg aggtcgatcc ctcggctgtc gaggagcact gcacccaact
    10441 gccggaacac ctgcggccca gccgaatccg ctgcgtctcc gaacgcgagg tcgcatccgt
    10501 ctacaccgca cacgggaagc tgtgacatgg ccgacgacaa ctcctccacc gtcaccaata
    10561 ccgaccagcc ggggctggac ggcacctacc gggtccgcgc cgacgcgttc tatgtccgcc
    10621 aggacgacgg cgtctggctg ggcaacaacg tcggctcctt ctccgtccgc ggtcaggggg
    10681 cctaccagtt ggtcagttcc ctcttcagca gcctggacgg agagcgcagc ctggccgaca
    10741 tctacggcga tctctccgag aacgcgcgcg gttcagtgtt gcgcctcgtg cgcgtgctgc
    10801 tgcacaacgg cttcatcaag gaggtcagcc atcccgtcga ggcggttccg gactggatgc
    10861 gcgagcgata cgccacccac ctttcctttc tggagcacca cgccgaccgt ccggtgaccc
    10921 ggctgcgcca ggtgcggacc cggcgcgtgg tctgcgccgg ccagggcatc gctctacacg
    10981 ccatgctcga cgccctgcgc gagtccggca tcgcccggct ggacgtgatc accgggaagg
    11041 aggacgcgga taccgtggag cagtcggccc aggtgcccga cagcggccac cgctggcggc
    11101 tgcactccac cgacggcggt ccgctggagg gcctcggcga ccacccggtc tgcgccgacg
    11161 ccgatgcggt cctgcttgcc tgcgatgacg ccgccccggc cgctctcggc caggtgcagc
    11221 gcctgctgcg ctcgcgcggc atcccggtcg gcgtcctcgg ccgctgcggg ccgttcacca
    11281 cggccgtgcc gccgatggct gaggcggcgt ggtgctggga gtgtgtgtac cgttccatcg
    11341 gtgtccccgc caacggggac gccgcggggc tggccctctc cgccgccccg gccaccgtgg
    11401 gtgcgctgcg actggcacaa caggtgttcg ccctgctggc cgacgtccgg atgcccgacg
    11461 ccgagtcggt gacgacggtg gagccgctgg ccccggtcgt acggcaccac actgtccacc
    11521 ggcacccgtg ctgtccgcac cacggccatg aggtcgccgc caccgcgcag ccggccccgg
    11581 ccgcgtctgg tgatgaggac ggatccgggg aggccgccgt gccggagacg gcggtgcgcc
    11641 cggacattcc catgcccgag gatcctccgg agcgtgtcgc cgtctccgac cgtatcgtcg
    11701 cggccgccgc cggcctgacc gactccttga ccggaccgct gctggcgctg ggagaggacg
    11761 acctgagcca gcttccgctg tcggccagct cctgccgggt ggtgcatccg gcaggggacg
    11821 cggaccggcc cgccgcgctg cgcgtgatct gccgggcgct ctcgccgcgc gaggcgcgca
    11881 accaggccgt gctgttcgcc atggaacggc tggccaccca ggtcgccgaa ctgaactggt
    11941 cggcggagcg gaacgccgcc cggtaccggt tcggcgccgg atggtcgctg gccgaggccc
    12001 ggttccgggc ccggctgcac gtcgcactgg acgcgccggc tgggagaccg catgaggccg
    12061 ccggaccgga ggagcgaccg gccgacggga ccgtcctggc gttcctcgca cagacactgg
    12121 ccggcctcgg tgccggcgcc cgatggcgcg ccggcgagct ggagaagccg gcgcacggcg
    12181 ctatacgggc ccgcatcacc accgccgacg gcgcgaccgc gaccggcgtc ggtacgcacc
    12241 gggatcaggc gctcgcccat gcgctggccc gcgccgtagc ggcgcgtacg ccgtccggcg
    12301 cggggccgca ggacctggag cacgtcgcat ttctcgctcc tcccgtccgt acctgggctc
    12361 agacggaggc ggccggcctc gctgcgcacg aggtcaccga gctgctgccg ttcctccggc
    12421 ccgcccgagg cggcggatcc ggcgggggcg ccacgctgcg ggtggtcgcc ctggcacccg
    12481 aggaggtgtc tcgatgaccc tgcctgccac ccgcgccgag cgtgccgccc ccggacccgt
    12541 ggtggtgggc gagagctacc tcgcccgcta tctggccgcc cggctcgccg cctctccggt
    12601 gccgccttgg cgcgcccgtg gacagcagga catcaccgtg ctggtgaccg agctcggcga
    12661 gctcggcgac taccaggaca ccatggtgga gagcttggtc atgggcaggc gactgctgtt
    12721 cgtgggcacc tggcgctccc tggcgtacct cgggccgctg tggacaccgg gcacccaggg
    12781 ttgcccgcgc tgcctggtga cccgcaccgc caacactccc tttggccccg gcctggacgg
    12841 agacgatctg gcggagtccc tgccgcatgc ccccgatgtg cggacttggg ggccgggggt
    12901 gctcggcatc atcgagcact atgtgcgggc cctgctgtcc acggacacag ccccgggtga
    12961 cacggccacg gaccgatggg tggtcgtggt ggacggcacc gctggttcag tggagcacca
    13021 gccgctgctg gccgactcga tctgccccgg ctgcggcgcg atcagcacgg acacgctgcc
    13081 cgagctgact ccccgcgagg ttccggtcac caagcccgac ccagcggtgc tgcgcaccgg
    13141 gcggctcgac ccggaccgcc tgtgccgaca gctgctcttc cctggcctgg gactgttcaa
    13201 ggaggtgcgc caggacctgc aaagcccgtt cggggcatgc tccgttgaac tgccgtcccg
    13261 ctgggggcgc cgggagccgg ccatcggccg cgcccgggac taccgctcca gccgggccat
    13321 cgccgtgctg gaaggactgg aacggtacgc ggggctgcag cgcggcggcc gggcggctcc
    13381 ggtgcgcgcc agctacgcgg acgtcgcgga ccgcgcgctg tatccgcctt cgctgggcac
    13441 ccatccgccg gagagccatc agatcgaggg gttccgctac cagcagttcc acccggacac
    13501 cgtcatcgac tgggtgccgg cctactcctt ccagcaggac ggtccggtgc tggtgccgga
    13561 gcgagcagcc ttctggggac cacgccacga cggcgagatc tcgttcttct acgacacctc
    13621 caacggctgc gccctgggca gctgcaccga ggaggcggtc ctgcacgggc tgcgcgaact
    13681 ggccgagcgc gatgcctttc tgctcacctg gtaccgccgc ctcgcccttc ccgaggtgca
    13741 gctggagggc gccgacgcgg ggctggacca actacttgcc aagtccgggc tgttcaccgg
    13801 tttccgcttc cgctgcttca acgcgagcat ggaatacggc atgccgacct tcgtcctgac
    13861 ggcggagagc tcccgggacg acggcccgcg gatgtttgcg ggaggcagcg cccatccgga
    13921 tccggtgcag gccgtgaccg gcggcctgca cgaactggtc ggtaccatcc tcgccacccg
    13981 ggactcctac cagcgcaacc gcggggcagc gctgcagatg ctggcggagc cggacctgat
    14041 gcgccgcatg gaggaccact cggcggtcgg agcgctcccc gaggcccgcg accgctacgc
    14101 cttcctcctc aaccggcccg ccccggccga gggactgctg ccgctcgcgg agatcccggg
    14161 caccctgcgg tcggaccagg acgacctgcg ggccgacttg catatcgcgc tggccggtgt
    14221 cctcgacgag gggatggacg tgctggtggt cgaccagacg atgcccgaac tgcggcgcaa
    14281 cggcgtgtgc tgcgtacggg tgctggtgcc cggcctgctg ccgatgacct tcggccaccg
    14341 caatcgccgt acggcgggac tgccccggct caccgagggc acatcgctgc cgtacgccgc
    14401 ccagccggac ccggacgcac cgatcggtgc cgtcccgcac cccttcccat gaagaaggtc
    14461 cgcgccgcgc ggacggcccc gtccctgtgg cctgtccagc ccgccgagaa gagaaacgga
    14521 ggggatcgca ccatggcaca gcccatcgtg cccgcgcccg tgaccaacga cgaactctat
    14581 gcgtacaccg agggactgcg gcgcgatcca cgcggagcca atccgcccga ctggcgggtg
    14641 gactgggccg acggcccctg gcccgtcacg gtgtacagcg ggggccggcg cactccactg
    14701 tccgccgcct ccaccgggcc tctcggcgcg cttcaccggg tgctgagcgg cagcctggcg
    14761 atcagcaggg tgcgccacga tcctgccggc ggcgtccagg ccacccccga gacgccggtg
    14821 ccgcaccgcg ggccgcgcat ccagctgcgc cggcccgtcc cgtccggcgg cggcatgtac
    14881 cccacggagg cgtatgtggt gccggccgag gaggacctcg tccaccacta ctgcccgtac
    14941 cggcatgagc tggtctgcct cggccgcacc ggtgccgcgg ccctgctccg ccggacgctg
    15001 gggttcgccg aggacgagcc cgcaggacac ctcgtggtac tcaccacccg cttctggaag
    15061 agtttctaca agtacggcga cttcaccgcc cggctcgccg ccgtggacgc cggcgtggtg
    15121 ctgggcgggg tcctgcggct ggccgaggcc gaaccgggcc ccacccgact gcgcaccggc
    15181 ttccccggag cggccgtcgc cgaatgcctc gggatcgcga ccaccgagga cgcgccgtgg
    15241 gcggtcctcg ggttcggccc gccggccggc ccccgcggcg cggcctcccc ggcctccgtc
    15301 cccgcgcccc cgcgcgccct ggagcggtcc cgccgggtca agcgctcggc cgccttcgac
    15361 cggctgcaac gggcctgcca ggagcccgcc gtcccgcctg cttcggtggc cgacggcgga
    15421 cctccaccgc caccgcccct gaagcccgtg cccctcgccg ccccacgctg cacggcgctg
    15481 ctcgacctcg ccgtacgggc ccgtcgtgcc tcccggggcg cgcggttcac cggggcggag
    15541 gtggagtgcg ccgccctggc ggccgtgctg cacaccgcgg cggatgcgct caaccggctc
    15601 gcccgcaccg gatccgggcc agccgcgcac tgggccgcgc acacccggct gcactgcgcg
    15661 gttcaccggg tgtccggcgt ggcgccggac tggtaccgct accagccgga ggcccaagcc
    15721 ttgctccgca ccggtgcgga cgccgatccg cgctgcgcgg tcaccgtccg caaggcgctc
    15781 ttcgccgcct ccttcaaccc ggaactcgcc gccttcacgg tgcatgtcag cactccgctg
    15841 gactggcggg cgtggcgagg gccggtggct taccgggagc agcaactcgc ggtgggggcc
    15901 gccgtggagg cgatcaccct ggccgccgcc accgaacggc tctccggcca tccggtcctc
    15961 ggcttcgacg cggacctcat cgaccgggcg taccggctgg tggacagcgg ccacggcgta
    16021 caggcgcaga tctgtgtcgg cgccgtgcgc acggacccgc aatgggagat gggaatttca
    16081 cagcggtgac cggaacagaa cagctgacag acaccgagcg gcggcagcgg ctgcccgagg
    16141 ccgacggcga ggggttcagc ccctacctcc tcttccggcg cggcaccctc acacccacgg
    16201 ccctggacgg gcttatcccc cagcgcacct gggagctgct ggaccgggcc gagcgctgcg
    16261 cgcaggcgcg tgaggaactg cgcggccgtc tggaggacgc cctctacgct gctgtccccg
    16321 gcatgcccgc cgcggagcgg cgcggcctgc tgcggctgcg ccggaccatc cacaacgacc
    16381 ggcccccggc cgcgctcccg agcctggccg ggctcccgcc ggagtgccgc gagctgctgg
    16441 agtcctggct gcggatgcgc accgaaggcg accggctgct cgacgaggcc gccgccgcac
    16501 tctccggcga actgaacgcc ggacgcacgg cactggccgc gctcatggcc cacgaggact
    16561 tccagcgcgg tgtgcagctc tccgatgagg gcacctggcg cgcgctgcgc ggctacgccg
    16621 ccgatcctca cgcgacgggc cgtaagccca gcagacggcg ccggctggag aacaccctca
    16681 ccagcttcgc ctaccgggtg gtgttcaagc cctctccctt cggctccttc actgagatcg
    16741 gcgcccgccc ctgggaccgg ccgggcgccg gcgggccggt cggcgacccg gccgcgcgcc
    16801 gcccggtgca ggtccgactg agcgtcggcc tactgtcgtg gatgagctac gagctgcggc
    16861 gcctggcggg cgccgaggac ctgatgcgga tccggctcaa taacaccctg atctcccacg
    16921 gcgaccgggt actgtgcgtc cgccgggccc cggacggcgc cgacgcctcc gcgttcgggg
    16981 cggcccaggt tgtctcggcc aagaacaccg agctggtgag gctgctgcgc cgactgctgt
    17041 ccgacggcga tctgaccgag cgcgccctcc gcgaccacct gacggcggcc ggacttgacc
    17101 cggacgccgc cgcccgcacc gtggacaagc tggtggaggt gggcctgtgc caccgcggac
    17161 tcgggctgcc ggaccagcag ccgcgcccgg cgcagaccgc cgccgcccgg ctgcgcgcct
    17221 ttcccgggcc acaggccgcc gagtgcgcgg agatctttgc gcggctgcag accatcgagg
    17281 acaccctcgc cggcgccgac gcggacgagc gcgccggcct gctggacgag gtgcgggagc
    17341 aggtcgcccg cttcgtcgag ttgtgtggcg ccccgacccc cgcgccggag gcgatgcgtt
    17401 cggtgctctt cgaggatgtc gggacctggg agccgccgca cgacgacccg accgcgctgt
    17461 tcgacggcga ccgggcctcc ctggagctct tccagcggat cgtgcccgtg ctggacgacg
    17521 cgtccatcga gaaggccggc ctgtacacgt acttcacccg gctgtacggc ggcgatgagc
    17581 gcccggtgcc ggccatcgag ttctaccggg ccttcgccga actcgcgccc aacgacgcag
    17641 cagcggtggc gacggggcag ggcgacgcgc actgcgactg gctgcgcgag ctgcgcacgg
    17701 aactcctcga cgaactgcgc gccgccgccg gccgggacgg tgaggtatgg ctggacgccg
    17761 cccggctgcg cgcctttgcc gaccgcctgc ccgcttccct gcctccctgg cgatcggcgg
    17821 cctaccgggt gcagatcgcc accgaggcag gtgagcgact ggccgtcgtc aacggagtca
    17881 ccaccggcca gggcgtgttc ttttcccgct tctgcgaact gctggaaacc accggcccgg
    17941 agggctggag cctcaccggc gcgctgcgct ggtggatccc ccggaatgcg ccgcggcaga
    18001 ccgatctaac cgccgttctc ggcctcaact tcaacctgca tccccgatta agcccccatg
    18061 agctggtcta ccctggatcc atcgcccgcc gtggcccgtc ggagccgctg acgctggcag
    18121 acctgtacgt ccgtgccgac caccgtcggc gccgactcca gctcgtctcc gcgcgggacg
    18181 gcgaaccggt cgacctggtg ccactgaact tcctttaccc ggcggcggca cccggcctgt
    18241 accgctttct gtgcgccttc gctcccaccc gcacctaccg cggcggcctg tgggagcagc
    18301 tggcccgtgc ggacgccagg tcgggccggg ccgtctcgcc cggaccccag cggcgccccc
    18361 gggtacggct gggtggcctg gtgttggacc gggcttcctg gagcttcccg gcccgggacg
    18421 tccccgagcc cgccggcggt ggggagtggg acaccgaggt gctggcccgc ttcgaccgct
    18481 ggcgccgcga gcacggcgtc ccgcgtcact gcttcttcca gctgatctcc gctccgccac
    18541 ccggcgacgg gtccggggac gggttggagg aagcccgcca gtgggccctt caagcccgca
    18601 gcgcccggct gcacaagccg cactacctcg actcccgtaa cccctttctg ctccaggtac
    18661 tcgcccggca gctgaccgag gccgccgacg ggaccgtgat ctttcacgag tgcctgccgt
    18721 cgcccgccga caccttggcg gcgcacccgc cgcggagcgc ggaggagttc tttgtggagt
    18781 acacgctttc ctcccgcccc tcccgcccgc atgttatgga ggatcaccgt gtccgggact
    18841 gaagccgccg cctggcagag cctgcacatc caccgttacg aagaccagga cggcttcctg
    18901 gtcgacggcc tcgacccggt gctgacgccg ctgcgcgcct cgggcgcggt ggaggagttc
    18961 ttctttctgc gctactggca gggcggccac cacatcaggc tgcgcctgcg gacctccctg
    19021 aagacggcgc aggaggtggc cgacgccctc gccgcgtatc tggcccgcca ccccgccggc
    19081 acgggcttcg acgccgagga gttcggtccc gcacaggcca ccatggccgt cctggaagcg
    19141 gagacgacga gcgaggtgct gccgcccgat tcggtgcacc acgccaccta cacccccgag
    19201 gtggagaagt acggaggcaa cctcggcgtg gccatcgcgg agcgcttctt cgccgcaagc
    19261 agcgatgtgg cgctggccac gctggcccgc ctccccggcg gctccgggaa gcggctcggc
    19321 gccgccttct ccacgatgct gcatgggctg tgcgccgccc ggctcacccc ggccgagatg
    19381 gccggcttct tcgcccacta ctgcgtgctc tggtcgccct atgtcttcga ccggttcctg
    19441 gcggactggc ctgagctgct gcgcgtgcgg cgggagcccg taggtcggca tgcggccacg
    19501 ctgctcgccc agtcccacca ggagccagcc gatccgtttg gccgcgcggt gggcaccgca
    19561 tggcgtgagc tggccgaatc cgccgacacg gtgctgcccg cggtcaccct gggcggcagc
    19621 gacgcgcccg tggcgcgacg gcggcagatt ctgctggtga gctatctgca cacgcacaac
    19681 aatcggcttg ggctgatccc cgagcaggag tcctttctcg gctggctcgg acaccacgtg
    19741 atgagcgaat acgccgggct tccccccgcg gccgacctgc tggaccgggt ccgggtcacc
    19801 cggcgcgaac gactcggcgc ctacgccgac ctcgcgccca cttcctgaaa ccctccaggg
    19861 cctgtccggc agcttgccgc actgcgcacg attcgctcgt tcggtcttgg ctcgcagtgc
    19921 atgggacgcc gcggcctgct ccaccaagat ccgccgacca ggccctggca caccctcttc
    19981 cgcacgccct cgaggagaat tcatggacgt caccgaccgc acttatccct tcgcccggca
    20041 ctgccccttc gccatgcccg aggagttcgg ctggcttcgc ggccgccaac cggtggccaa
    20101 ggtacggctc gaaagcggtg acgaggcatg gctgatcacc cgctacgagg atgtacgcgc
    20161 cgcgctgacc gacccccggt tcagccggtc gattcaccgg gacggtgccg ctcgcgtgga
    20221 cacgggcttc caggccgacg ccgacagccc gctgttcaac ttcggcggca ccatctccga
    20281 gcccccgggc cacacccgct ggcgtcgcat cgtcaaccgc gccttcacct cccggcaggc
    20341 cgagtcgatg cgcaaggaga tcgccgcgca caccgacgcc ctcctcggtg aactggccgc
    20401 ccgcggcgag ggcttcgacc tgatggcaga cttcgcctac cggctgccga ttaccgtgat
    20461 ttgcgacctg ctgggcctcg aggacgccgc ccgcccggag ttcaccgagc tggcggccca
    20521 gctcacgcgt cgcgacatgc agtcctcctt cattgagttc gggcaggcgc tccaggcgat
    20581 cggccgctac gcggtcggcc tgatcgtccg caagcggaag aacctgggcg atgacctgct
    20641 gagcaccctg ataaccctcc gtgacgagga gggcgacgcc gaagggctca ccaacgagga
    20701 attggtctcc acggtgattc tgctgctcat ggccggctat gaaagcaccg ccgtgcaact
    20761 gggcaacgcc ttctacgcct tgctgcgcga ccccgatcag atgcgcgctc tgcgcgagca
    20821 cccggagcgg atcgaccacg cagtcgagga gctgctgcgc tacgcacaga tgggcaccgg
    20881 atacgccatc gccaagttca ccaccgcgga cgtcgagatg tccggcgtga cgatcccggc
    20941 cggatccacc gtcttcgttt cgctggcctc ggccaaccgc gacgagcgga tcttcggaac
    21001 ggacgccgac accctggacc tgaaccgggc ggaggcgcgc cggcagacgg cgttcggcta
    21061 cggcccgcac tactgcctgg gcgcggcgct ggcccgggtg gagatgcagg aggcggtcgc
    21121 ccgtaccctg gcccgcttcc cgggcctgca ccatgacggc gacctggacg cggtggagct
    21181 caacagcaac ctcttcacct actacccgcg cgagctgcgc gtcctgcctt gaccccgccg
    21241 ttccgccacc accggaggag cccgatggac atcgcacaag aagccgacgc ctatccgttc
    21301 ccgctcacct gccccttcac ccagccgccc gagctggccc ggcgtcgcaa cgaggcgccc
    21361 atcgctcccg tgaccctgcc cggcggcgcc cccgcctggc tggtgactcg cttcgacgac
    21421 gtccgcaccg tccttaccga cgagcggttc agccgtagcc cggtccggca gaacgcggtg
    21481 cgcgagcagc accgtgcagg accggccccc ggcccggggc agttcgactt cggtgcccag
    21541 ctggccgacc ccgccaccca cgcccgctgg cgctcccggc tcggctcggt gctcaccccg
    21601 cagcatgccg agtccctgcg cccgcggatc gggcagatcg tcgatgcggc cctggacgag
    21661 atagccgcac gccctgacca tacggccgag ttcgtctcgg acttcgctta ccggatcccg
    21721 gtccaggtgc tcgccgggct cttcgaccta accccgcagt tgtgcgaccg gcttcaggac
    21781 tgggccaccc ggctgcgcgg cgccgcaccc tcgaccgcgg ccttcggtga ggcgatgcgc
    21841 tcgctgtacg gggtcgccgc cgagctggtg gccagggagc gtgccgagcc cgggcccgga
    21901 gtgatcgggc tgctgctctc cgcagaccgg gagggcgcgg agacgatgac cgatgaggag
    21961 ctggtctcca ccgtcttcct cctggccacc gccggatacg aatccaccgc cgtgcagttc
    22021 gccaacggcc tgctcgccct cttccagcac ccggccaagc tggagcggct gcggtcgggc
    22081 tcggtgtcga tggccaccgc cgtcgaggag atcctgcgct atgcccaggc cggaaccggc
    22141 tttgcaggca ccacctacac cactgaggag gtgcggctcg gcgaggtcgc cctcccggcc
    22201 ggggcgacgg tgctgatctc cctggactcg gccggccggg acgagcggcg caccgaccgg
    22261 cccgaggtgt tcgacccctc gcgcggtgcg cctcaccatc atctgacctt cggcgcgggc
    22321 gggcacttct gccttggcgc ggccgtggcc cgggttgagc tccaggaggg cttcacccgg
    22381 ctgctcgcgc ggttccccgg actgcggccg tccggcgatc cctggaagac cgagttcacc
    22441 cgcaacctct tccaccacta cccgcgcgaa ctccgggtgg agtggtgact ggtcaccgag
    22501 aggaagtcga tatgagcgac caggccccgt ccctgtactg ctccatcatt ctgtgggacc
    22561 tgtcgcggtc ctcgcagacg gtccgctccc tgcgcgcata cctgcgggac tatgcggtcg
    22621 acagctatga gaagatgccc ggcctgcggc agaaggtgtg gatctcctcg accggtccgg
    22681 agggagaact ctggggcgcg gtctatctgt gggactcgca ggaggccgct tacggccgac
    22741 cgcctggggt gtcacatgtg gtcgagctga tcggctaccg ccccaccgag cgccgctact
    22801 tcggcgtgga ggccgcggcc acgggtctgg acagcctggt gggcgcgctg accgcggggg
    22861 tggggatggc tttccagccg ggatctcccg agccgtcggc ccgcccgcag gaatttgtgc
    22921 cgcccggcgc cgacaccttc atccccgccg gggcgaaccc gggcagcggc ccgcccgtca
    22981 gctgagggac gcgtcggtcc acgcccgtac ctgggcgtgg tgctcccgcc aggcgtccca
    23041 cacatcccca gcccaggccc gcagttgctt gccgtactcc gtggcgtccg ccgcggcgac
    23101 atcggcggcg gtgagcttct tgtgcaggtc ctgggctgag gggtgcggct cgagccgggt
    23161 gaaccgcgcc ctgtgcacca tgcgacggtg caactgcggc ccgtgctggg gatcggcgcc
    23221 gcgttccaga aagaggtaca aggtcatcag gcagatggac agccgctgcg tggcgacggg
    23281 gtcctccccg cccgggtgct gcacgctgta gctgtccacc agcagctggt ggtgcggctg
    23341 ccgctcaggg gcgttgtacg acagcgcgag cagctccagg taggcggggc cgcagcgggc
    23401 acagcccccg gtgacaccat ccgcgtcgct ctgtcccgtc atgcactttc cttgccctgt
    23461 tgtgctctcg tacttcgtgt tcgtctgttc gtctgttcgt cgggtcaacg ccggtcggcg
    23521 ctcagcgcca gtgccgccca gccccgcacg gtgtcgtgct gctccgccca ggccgcccag
    23581 accgaccaag cccactcctc gatcacctgg tgacgctcct cgggggccgc ccggtccacg
    23641 tccctcacgg tgatctgccc gaggtcggat ggcggcgcca gcgccggcca ctccggcatc
    23701 ttcaggcgcg gcagtaccga ccggctgagc gatgtcatca tgcgccgcag ccgctcctcg
    23761 cgcacccggt tttccacatg caggcagagc gccatcagat gcaccgcgac cgactgccgc
    23821 tgccgacggt cgtcttcccc gccgagggga tgttgcgccg cgtatgcgtc cgtggcaagt
    23881 cgcgtcgcct ccggaccgag ttcggcgagg agccggcaga agaggcccca gcagacggcc
    23941 tcggtggaca tataggcgtg taccggtccc gacgcgtcgc cttccccgac cagcccgcac
    24001 ccgggacagg ccgcagcgtc gtgcggtgac caccgacagt ccttcatgtc acggattatg
    24061 ccgcagcggg attgtcgccg cggagccgcg gtctcacacc tgtttcctcg acatcctgcg
    24121 ccacgcaggg aatcgctttt ggaccgactg gcaaatggat cacttgaagc gtcgggtggt
    24181 gggcggctgt ccccgcgata gcagctcgtc gaacgccgga tgagcatgcg gagcgtgacg
    24241 aaagtggcgg cgaggtagag gtagaggcgc cgtccgcctc gccgggacgt tcccgggcca
    24301 ccgacatgtc cgaggaagga cagtacggtc gatccgagtg cgggccagga ggccgcgaga
    24361 gcatcccggc accggcatcc tggcgcgtct atcgctgtgc gggtcaagag gcccgggaca
    24421 tgcggtactc acatactcac tgcccgaatg gtgctgggcc ccgacgctgc gatgcgtgag
    24481 cgatgcgtga gcggacaggg cggcacacgt tggactgggc gtcacgccca cgacgtcgac
    24541 aagcctctga ccaggcggaa aaggacttgg cgtgatcacg tggcaccacc cgtcacgatc
    24601 ttgctggccc tcgtaatgcg taggtctcgg gttcgaaccc cgaaggcggc tccacttaga
    24661 actcctaacg aaatgatctt cgaggtggtt ggatcactcc gggaacgttg atccgggggt
    24721 gtggggtggc tcggccgaag ccgtgggaag ttgacgacga gttgtgggcg gtgatcgagc
    24781 cgctgttgcc caaggtggag cgtcgggtcc ggcatccggg gcgcaagcgg catccggacc
    24841 ggctggtgtt ccagggcatc ctgttcgtcc tgcacaccgg gatctcctgg gaacaccttc
    24901 cgcaggaact cggcttcggc tcgggcatga cctgctggcg ccgcctggcc gagtggactg
    24961 aggccggcgt gtggccccgg ctgcacgagt tcctcctcgc caggctccgc agcgcgaacg
    25021 ccctggactt ctcccgggcg gcggtcgacg gctcccacat ccgggcgtta aagggggagc
    25081 caagaccgga cgaagccctg tcgaccgggg caggatgggc agcaagcatc acctgatcac
    25141 cgacgccacc ggcatcccgc tcgccgtcac cctgaccggc ggcaaccgta acgacgtcac
    25201 ccagctgatc ccactcctcc aggctgtgcc tcccgtgcgg ggcaagcgcg gcaggccccg
    25261 gcgccgcccg gacgtggtgc tgggcgaccg cggctacgac cacgacaagt accggcgtct
    25321 ggtctggggc ctcggcgtga aaccgctgat cgcccgccgg ggcaccgagc acggctccgg
    25381 gctcggcacc caacgctggg tcgtggagcg cgcgtttgcc cacctccact ggtttcgccg
    25441 cctgcggatc cgctgggaga tccgcgacga catccacgaa gccttcctca ctctcggatg
    25501 cgcactcatc tgctggcgac gcctggcagc agttcaacgc cgccactcat agacacccgg
    25561 tgaggactgc aggacctcgc tcggccactc cttcagcacc cgtccaagca gccttcgctg
    25621 ctcgtcgacc caaccctctt caaggcgcat gggaaggaac acggagacgc acgaactgcc
    25681 cggatcctct acatggacag cgggagtctc gtgctcttcg ttgtgcggct ggatcctgat
    25741 ctcagggctg tggtcgtcgt ccctccagca gatgtcctga cctgcagcga ggagatccag
    25801 agcccgggac cagtcctcca ggtcggaagg gaacagagac atgcccagtc gaccgctgac
    25861 gaagctgctc gtgatcagga cctctgcgtc gagctggtcg tgaagatgca gcacacccgg
    25921 cgaccgacgt cccagcacac gcacccggaa accgttgtca ccatccgaga ggctgatcag
    25981 atccaccgtg caccctctgc ttaccttcgc ccgcaagggc tcatggtgcc gaagcagagc
    26041 tgcagccaca accagattgt cgcagtctca ttccgttagg agttcttagg accaggtcag
    26101 gtaccctctg acctggcctt ttgtgttgag aagccgttgt ctttccggat gtgagcgttg
    26161 agtttccgct gttcaggttt cagaagccgt atctcaaccg atcatggaac ttgcgggtcg
    26221 aacaggtttc ccgccggggt gatcttcccg ttgtgcgcgc atgaagacag ggcctctcgg
    26281 tagctcgggg atgcgaatct gaccgagcag cgccgggagg ccctggtgtc gttgttgtac
    26341 gcgtccgaac ccgttcagtt caactcggcg gctccatcgt gtgattgcct cgcgcatgtg
    26401 tacggcaacg cggccgacca tccggaccgg gaacgccggt atccctccga catgacggac
    26461 gcggaatggg cggccgtccg gcctttgctg ccggtgccgg cctggctgaa gggccggggc
    26521 gggcagcccg agggctactg ccaccgccag ctgctggacg cgatccgcta cctggtcgcg
    26581 ggcgggatct cctggcgggc gatgcccgcg gacttccccg actggggccg ggtctacgcc
    26641 ttcttccgcc gctggcgcga gcacgggctg atcacggagt tccacgaccg gctgcgcgga
    26701 cgggtgcgtg agcgggaggg ccgtgaggcg gagccgacgg ccgggatcat cgacgcgcag
    26761 tcggtgaagg ccgcggcctc ggtgccgtcc gtctcacgcg gctacgacgg cgggaagaag
    26821 gtgggcggcc gcaagcggca catcgtgacc gactgcctcg gcctgctcct ggtcgtcgcg
    26881 gtgactgccg cgaacatcgg cgaccgggat gctgcgacgg gcctgctgac ccggctgcgc
    26941 cgcctgcacc gtgacatctg cctggtctgg gccgacggcg gctacaccgg cggcctcgtc
    27001 gactggtgcc gggacaaact cgccctgact ttggagatcg tcaagcgcac cgacgacatg
    27061 acgggattcg tggtgctgcc caggcgctgg gtggcagaac gcacgttcgc gtggctgatg
    27121 cattcgcgcc gactggcccg ggactacgag acgttgctgg ccagcagcga ggcgatgatc
    27181 cggtggtcga tggtcacgcg gatgagccgt cgcctggcac ggccacaggc cgccggccgg
    27241 cactga
//
