BGC0001709: nystatin biosynthetic gene cluster from Streptomyces albulus
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Location: 1 - 119,206 nt. (total: 119,206 nt).
This entry is originally from NCBI GenBank MG742725.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001709
Short description nystatin biosynthetic gene cluster from Streptomyces albulus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MG742725.1
1 - 119206
via
Compounds
  • nystatin
Species Streptomyces albulus [taxonomy]
References
Chemical products information
nystatin Evidence:
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C47H75N1O17
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AVX51094.1
  • nysF
 1 - 228 (-) nysF
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    • AVX51095.1
    • nysG
    		 396 - 2216 (-) nysG
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      • AVX51096.1
      • nysH
      		 2194 - 3948 (-) nysH
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        • AVX51097.1
        • nysDIII
        		 4250 - 5284 (+) nysDIII
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          • AVX51098.1
          • nysI
          		 5463 - 33974 (+) nysI
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            • AVX51099.1
            • nysJ
            		 33995 - 50275 (+) NysJ
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              • AVX51100.1
              • nysK
              		 50331 - 56501 (+) nysK
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                • AVX51101.1
                • nysL
                		 56649 - 57833 (+) nysL
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                  • AVX51102.1
                  • nysM
                  		 57918 - 58109 (-) nysM
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                    • AVX51103.1
                    • nysN
                    		 58159 - 59355 (-) nysN
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                      • AVX51104.1
                      • nysDII
                      		 59352 - 60410 (-) nysDII
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                        • AVX51105.1
                        • nysDI
                        		 60429 - 61820 (-) nysDI
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                          • AVX51106.1
                          • nysA
                          		 62177 - 66307 (+) nysA
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                            • AVX51107.1
                            • nysB
                            		 66353 - 75931 (+) nysB
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                              • AVX51108.1
                              • nysC
                              		 75951 - 109190 (+) nysC
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                                • AVX51109.1
                                • nysE
                                		 109494 - 110243 (+) nysE
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                                  • AVX51110.1
                                  • nysRI
                                  		 110654 - 113551 (+) nysRI
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                                    • AVX51111.1
                                    • nysRII
                                    		 113575 - 116433 (+) nysRII
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                                      • AVX51112.1
                                      • nysRIII
                                      		 116423 - 119206 (+) nysRIII
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                                        Biosynthesis information
                                        Annotation changelog

                                        Entry version: 4

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-10-07
                                        Update chemical activity to schema version 2.11
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 3

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Updated bioactivity data
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2019-10-16
                                        Migrated from v1.4
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2019-10-16
                                        Updated reference publication(s) (MIBiG Annotathon)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2018-08-06
                                        Submitted
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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