BGC0001711: occidiofungin A biosynthetic gene cluster from Burkholderia pyrrocinia
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Location: 926 - 56,163 nt. (total: 55,238 nt).
This entry is originally from NCBI GenBank JPWP01000009.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001711
Short description occidiofungin A biosynthetic gene cluster from Burkholderia pyrrocinia
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
JPWP01000009.1
926 - 56163
via
Compounds
  • occidiofungin A
Species Burkholderia pyrrocinia [taxonomy]
References
Chemical products information
occidiofungin A Evidence:
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C54H78N12O19
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • JM78_19255
  • KFL51877.1
 926 - 1645 (+) oleoyl-ACP hydrolase
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    • JM78_19260
    • KFL51878.1
    		 1802 - 2752 (+) NAD-dependent dehydratase
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      • JM78_19265
      • KFL51879.1
      		 2951 - 4261 (+) 2,4-diaminobutyrate 4-aminotransferase
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        • JM78_19270
        • KFL51880.1
        		 4340 - 5326 (+) taurine catabolism dioxygenase TauD
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          • JM78_19275
          • KFL51881.1
          		 5523 - 9926 (+) beta-ketoacyl synthase
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            • JM78_19280
            • KFL51882.1
            		 9923 - 13246 (+) short-chain dehydrogenase
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              • JM78_19285
              • KFL51883.1
              		 13243 - 26646 (+) amino acid adenylation protein
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                • JM78_19290
                • KFL51884.1
                		 26657 - 28273 (+) beta-lactamase
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                  • JM78_19295
                  • KFL51885.1
                  		 28261 - 32175 (+) amino acid adenylation protein
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                    • JM78_19300
                    • KFL51886.1
                    		 32214 - 41282 (+) amino acid adenylation protein
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                      • JM78_19305
                      • KFL51887.1
                      		 41370 - 50867 (+) amino acid adenylation protein
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                        • JM78_19310
                        • KFL51888.1
                        		 50864 - 51520 (+) glycosyl transferase
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                          • JM78_19315
                          • KFL51889.1
                          		 51584 - 52063 (+) hypothetical protein
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                            • JM78_19320
                            • KFL51890.1
                            		 52080 - 53780 (+) ATP-binding protein
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                              • JM78_19325
                              • KFL51891.1
                              		 54133 - 55038 (+) LuxR family transcriptional regulator
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                                • JM78_19330
                                • KFL51892.1
                                		 55149 - 55340 (+) hypothetical protein
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                                  • JM78_19335
                                  • KFL51893.1
                                  		 55351 - 56163 (-) LuxR family transcriptional regulator
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                                    Biosynthesis information

                                    Biosynthetic modules

                                    Name
                                    Unk01
                                    Type
                                    nrps-type1
                                    Genes
                                    JM78_19285
                                    Substrates
                                    serine (evidence: Structure-based inference, Sequence-based prediction)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk02
                                    Type
                                    nrps-type1
                                    Genes
                                    JM78_19295
                                    Substrates
                                    R-beta-hydroxytyrosine (evidence: Structure-based inference, Sequence-based prediction)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk03
                                    Type
                                    nrps-type1
                                    Genes
                                    JM78_19300
                                    Substrates
                                    2,4-diaminobutyric acid (evidence: Structure-based inference, Sequence-based prediction)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk04
                                    Type
                                    nrps-type1
                                    Genes
                                    JM78_19300
                                    Substrates
                                    glycine (evidence: Structure-based inference, Sequence-based prediction)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk05
                                    Type
                                    nrps-type1
                                    Genes
                                    JM78_19305
                                    Substrates
                                    asparagine (evidence: Structure-based inference, Sequence-based prediction)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk06
                                    Type
                                    nrps-type1
                                    Genes
                                    JM78_19305
                                    Substrates
                                    serine (evidence: Structure-based inference, Sequence-based prediction)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Annotation changelog

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Added NRP substrate specificities
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2019-10-16
                                    Updated compound(s) information (NPAtlas curation)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2018-08-06
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    Detailed domain annotation
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