BGC0001715: octapeptin C4 biosynthetic gene cluster from Bacillus circulans
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Location: 1 - 50,126 nt. (total: 50,126 nt).
This entry is originally from NCBI GenBank LN999013.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001715
Short description octapeptin C4 biosynthetic gene cluster from Bacillus circulans
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LN999013.1
via
Compounds
  • octapeptin C4
Species Bacillus circulans [taxonomy]
References
Chemical products information
octapeptin C4 Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CUX79054.1
  • fabG
 247 - 1014 (+) 3-oxoacyl-[acyl-carrier-protein] reductase FabG
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    • CUX79055.1
    		 1011 - 3134 (+) Heparinase II/III-like protein
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      • CUX79056.1
      		 3127 - 5436 (+) Heparinase II/III-like protein
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        • CUX79057.1
        • ectB
        		 6332 - 7618 (+) Diaminobutyrate--2-oxoglutarate transaminase
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          • CUX79058.1
          		 7684 - 9261 (+) PGAP1-like protein
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            • CUX79059.1
            • sfp
            		 9271 - 9981 (+) 4'-phosphopantetheinyl transferase sfp
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              • CUX79060.1
              • octA
              		 10101 - 22370 (+) Octapeptin synthase subunit A
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                • CUX79061.1
                • octB
                		 22456 - 37146 (+) Octapeptin synthase subunit B
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                  • CUX79062.1
                  • octC
                  		 37259 - 40510 (+) Octapeptin synthase subunit C
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                    • CUX79063.1
                    		 40500 - 42326 (+) Putative multidrug export ATP-binding/permease protein
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                      • CUX79064.1
                      		 42323 - 44056 (+) putative ABC transporter ATP-binding protein
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                        • CUX79065.1
                        		 44174 - 45229 (-) alkanesulfonate transporter substrate-binding subunit
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                          • CUX79066.1
                          • cmpB
                          		 45288 - 46010 (-) Bicarbonate transport system permease protein CmpB
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                            • CUX79067.1
                            • cmpC
                            		 45985 - 46824 (-) Bicarbonate transport ATP-binding protein CmpC
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                              • CUX79068.1
                              		 46997 - 47920 (+) hypothetical protein
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                                • CUX79069.1
                                • degU
                                		 47917 - 48609 (-) Protease production enhancer protein
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                                  • CUX79070.1
                                  • narX
                                  		 48658 - 49788 (-) Nitrate/nitrite sensor protein NarX
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                                    Biosynthesis information

                                    Biosynthetic modules

                                    Name
                                    Unk01
                                    Type
                                    nrps-type1
                                    Genes
                                    octA
                                    Substrates
                                    2,4-diaminobutyric acid (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk02
                                    Type
                                    nrps-type1
                                    Genes
                                    octA
                                    Substrates
                                    2,4-diaminobutyric acid (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk03
                                    Type
                                    nrps-type1
                                    Genes
                                    octA
                                    Substrates
                                    2,4-diaminobutyric acid (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk04
                                    Type
                                    nrps-type1
                                    Genes
                                    octB
                                    Substrates
                                    leucine, phenylalanine (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk05
                                    Type
                                    nrps-type1
                                    Genes
                                    octB
                                    Substrates
                                    leucine (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk06
                                    Type
                                    nrps-type1
                                    Genes
                                    octB
                                    Substrates
                                    2,4-diaminobutyric acid (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk07
                                    Type
                                    nrps-type1
                                    Genes
                                    octB
                                    Substrates
                                    2,4-diaminobutyric acid (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk08
                                    Type
                                    nrps-type1
                                    Genes
                                    octC
                                    Substrates
                                    leucine (evidence: Sequence-based prediction, Mass spectrometry, Structure-based inference)
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Annotation changelog

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Added NRP substrate specificities
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2018-08-06
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    Detailed domain annotation
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