BGC0001716: odilorhabdin NOSO-95A biosynthetic gene cluster from Xenorhabdus nematophila AN6/1
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Location: 2,367,833 - 2,440,325 nt. (total: 72,493 nt).
This entry is originally from NCBI GenBank LN681227.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001716
Short description odilorhabdin NOSO-95A biosynthetic gene cluster from Xenorhabdus nematophila AN6/1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LN681227.1
2379690 - 2423130
via
Compounds
  • odilorhabdin NOSO-95A
  • odilorhabdin NOSO-95B
  • odilorhabdin NOSO-95C
Species Xenorhabdus nematophila AN6/1 [taxonomy]
References
Chemical products information
odilorhabdin NOSO-95A Evidence:
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C54H101N23O14
Chemical database entries
PubCHEM
odilorhabdin NOSO-95B Evidence:
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C54H101N23O13
Chemical database entries
PubCHEM
odilorhabdin NOSO-95C Evidence:
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C54H101N23O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • XNC2_2360
  • CEK23354.1
 2379690 - 2380187 (+) hypothetical protein
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    • XNC2_2361
    • CEK23355.1
    		 2380489 - 2380842 (+) conserved hypothetical protein
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      • XNC2_2362
      • CEK23356.1
      		 2380899 - 2381462 (-) conserved hypothetical protein
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        • XNC2_2363
        • CEK23357.1
        		 2381416 - 2381721 (-) conserved hypothetical protein
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          • XNC2_2364
          • CEK23358.1
          		 2381705 - 2381791 (-) hypothetical protein
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            • XNC2_2365
            • CEK23359.1
            		 2381852 - 2384257 (-) putative Aculeacin A acylase precursor [Contains: Aculeacin A small subunit; Aculeacin A large subunit]
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              • XNC2_2366
              • CEK23360.1
              		 2384254 - 2385213 (-) putative Clavaminate synthase
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                • XNC2_2367
                • CEK23361.1
                		 2385295 - 2386038 (-) conserved hypothetical protein
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                  • XNC2_2368
                  • CEK23362.1
                  		 2385975 - 2386235 (-) hypothetical protein
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                    • XNC2_2369
                    • CEK23363.1
                    		 2386114 - 2387742 (-) putative transport proteins (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal))
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                      • XNC2_2370
                      • CEK23364.1
                      		 2387833 - 2398761 (-) putative Phenylalanine racemase (ATP-hydrolyzing)
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                        • XNC2_2371
                        • CEK23365.1
                        		 2398758 - 2402174 (-) conserved hypothetical protein
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                          • XNC2_2372
                          • CEK23366.1
                          		 2402174 - 2412007 (-) putative Ornithine racemase
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                            • XNC2_2373
                            • CEK23367.1
                            		 2412004 - 2420325 (-) putative Ornithine racemase
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                              • XNC2_2374
                              • CEK23368.1
                              		 2420470 - 2420925 (-) conserved hypothetical protein
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                                • XNC2_2375
                                • CEK23369.1
                                		 2420944 - 2421801 (-) conserved hypothetical protein
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                                  • XNC2_2376
                                  • CEK23370.1
                                  		 2421823 - 2423130 (-) Diaminobutyrate--2-oxoglutarate transaminase (Diaminobutyrate--2-oxoglutarate aminotransferase) (L-2,4-diaminobutyric acid transaminase) (DABA aminotransferase)
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                                    Biosynthesis information

                                    Biosynthetic modules

                                    Name
                                    Unk01
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2370
                                    Substrates
                                    N6-hydroxylysine, lysine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk02
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2370
                                    Substrates
                                    beta-hydroxyarginine, dehydroarginine, arginine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk03
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2370
                                    Substrates
                                    N6-hydroxylysine, lysine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk04
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2371
                                    Substrates
                                    histidine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk05
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2372
                                    Substrates
                                    glycine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk06
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2372
                                    Substrates
                                    ornithine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk07
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2372
                                    Substrates
                                    proline (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk08
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2373
                                    Substrates
                                    lysine (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Name
                                    Unk09
                                    Type
                                    nrps-type1
                                    Genes
                                    XNC2_2373
                                    Substrates
                                    3R-hydroxy-2,4-diaminobutyric acid, 2,4-diaminobutyric acid (evidence: Structure-based inference [1])
                                    Integrated Monomers
                                    Domains
                                    adenylation
                                    Annotation changelog

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Add compound details
                                    • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2022-09-15
                                    Added NRP substrate specificities
                                    • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2022-09-15
                                    Switch to GenBank accessions
                                    • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2018-08-06
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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