BGC0001717: okaramine B biosynthetic gene cluster from Penicillium simplicissimum
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Location: 2,899 - 22,560 nt. (total: 19,662 nt).
This entry is originally from NCBI GenBank LC316945.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001717
Short description okaramine B biosynthetic gene cluster from Penicillium simplicissimum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: LC316945.1
Compounds
  • okaramine B
Species Penicillium simplicissimum [taxonomy]
References
Chemical products information
okaramine B
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C33H34N4O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBB04327.1
  • okaA
 2899 - 8973 (-) nonribosomal peptide synthetase
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  • BBB04328.1
  • okaB
 9879 - 11460 (+) flavin monooxygenase
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  • BBB04329.1
  • okaC
 11859 - 13213 (-) dimethylallyltryptophan synthase
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  • BBB04330.1
  • okaD
 13714 - 15303 (+) cytochrome P450
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  • BBB04331.1
  • okaE
 16381 - 17283 (+) alpha-ketoglutarate-dependent dioxygenase
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  • BBB04332.1
  • okaF
 18877 - 20255 (+) methyltransferase
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  • BBB04333.1
  • okaG
 20674 - 22560 (-) cytochrome P450
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
okaA
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Fix biosynthetic class
  • Added NRP substrate specificities
Detailed domain annotation
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