BGC0001726: pactamide A biosynthetic gene cluster from Streptomyces pactum
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Location: 1 - 31,637 nt. (total: 31,637 nt).
This entry is originally from NCBI GenBank KU569222.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001726
Short description pactamide A biosynthetic gene cluster from Streptomyces pactum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
KU569222.1
via
Compounds
  • pactamide A
  • pactamide B
  • pactamide C
  • pactamide D
  • pactamide E
  • pactamide F
Species Streptomyces pactum [taxonomy]
References
Chemical products information
pactamide A Evidence: NMR [1]
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C29H40N2O4
Chemical database entries
NPAtlas
PubCHEM
pactamide B Evidence: NMR [1]
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C29H38N2O5
Chemical database entries
PubCHEM
NPAtlas
pactamide C Evidence: NMR [1]
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C29H38N2O4
Chemical database entries
NPAtlas
PubCHEM
pactamide D Evidence: NMR [1]
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C29H38N2O5
Chemical database entries
NPAtlas
PubCHEM
pactamide E Evidence: NMR [1]
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C29H36N2O4
Chemical database entries
PubCHEM
NPAtlas
pactamide F Evidence: NMR [1]
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C29H39Cl1N2O5
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • APD26277.1
 12490 - 13680 (-) hypothetical protein
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    • APD26278.1
    		 14290 - 15195 (+) PtmD
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      • APD26279.1
      		 15332 - 24676 (+) PtmA
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        • APD26280.1
        		 24663 - 26348 (+) PtmB1
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          • APD26281.1
          		 26360 - 28003 (+) PtmB2
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            • APD26282.1
            		 28000 - 29055 (+) PtmC
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              • APD26283.1
              		 29052 - 30143 (+) XiaA
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                • APD26284.1
                		 30202 - 30696 (-) XiaB
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                  • APD26285.1
                  		 30861 - 31637 (-) XiaC
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                    Biosynthesis information

                    Biosynthetic modules

                    Name
                    Unk01
                    Type
                    nrps-type1
                    Genes
                    APD26279.1
                    Substrates
                    ornithine (evidence: Structure-based inference, Homology)
                    Integrated Monomers
                    Domains
                    adenylation
                    Annotation changelog

                    Entry version: next

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2024-07-25
                    MIBiG v4 annotathon
                    • (ID: EMAUK5TYS6O5PLPCDCIRFTNF)
                    • (ID: CVBS4CX3MGQ2Y6Q45INSO263)
                    • (ID: EGFTGGHJSKF7A4VDS6DUN5J2)
                    • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Added NRP substrate specificities
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2018-08-06
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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