BGC0001727: paenilan biosynthetic gene cluster from Paenibacillus polymyxa E681
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1,552,554 - 1,565,755 nt. (total: 13,202 nt).
This entry is originally from NCBI GenBank CP000154.2.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001727
Short description paenilan biosynthetic gene cluster from Paenibacillus polymyxa E681
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
CP000154.2
1552554 - 1565755
via
Compounds
  • paenilan
Species Paenibacillus polymyxa E681 [taxonomy]
References
Chemical products information
paenilan Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • PPE_01446
  • ADM69285.1
  • pnlR2
 1552554 - 1553273 (+) transcriptional response regulator
    copy AA seq
    copy Nt seq
    • PPE_01448
    • ADM69286.1
    • pnlK
    		 1553270 - 1554340 (+) sensor histidine kinase
      copy AA seq
      copy Nt seq
      • PPE_01449
      • ADM69287.1
      • pnlF
      		 1554485 - 1555408 (+) ABC transporter ATP-binding protein
        copy AA seq
        copy Nt seq
        • PPE_01450
        • ADM69288.1
        • pnlG
        		 1555405 - 1556112 (+) ABC transporter permease
          copy AA seq
          copy Nt seq
          • PPE_01451
          • ADM69289.1
          • pnlE
          		 1556127 - 1556861 (+) ABC transporter permease
            copy AA seq
            copy Nt seq
            • PPE_01452
            • ADM69290.1
            • pnlC2
            		 1556862 - 1558223 (-) cyclase
              copy AA seq
              copy Nt seq
              • PPE_04953
              • ADM69291.1
              • pnlA
              		 1558420 - 1558572 (+) lantibiotic paenilan precursor peptide
                copy AA seq
                copy Nt seq
                • PPE_01453
                • ADM69292.1
                • pnlC1
                		 1558649 - 1559911 (+) cyclase
                  copy AA seq
                  copy Nt seq
                  • PPE_01454
                  • ADM69293.1
                  • pnlR1
                  		 1559961 - 1560638 (+) transcriptional response regulator
                    copy AA seq
                    copy Nt seq
                    • PPE_01455
                    • ADM69294.1
                    • pnlB
                    		 1560613 - 1563867 (+) dehydratase
                      copy AA seq
                      copy Nt seq
                      • PPE_01456
                      • ADM69295.1
                      • pnlT
                      		 1563854 - 1565755 (+) paenilan transporter
                        copy AA seq
                        copy Nt seq
                        Biosynthesis information
                        Annotation changelog

                        Entry version: next

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2024-07-25
                        MIBiG v4 annotathon
                        • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2018-08-06
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Similar known gene clusters from MIBiG 4.0
                        Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                        Click on reference genes to show details of similarities to genes within the current region.
                        Click on an accession to open that entry in the MiBIG database.