BGC0001729 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001729 (Penicillium brasilianum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	47,451	paraherquonin	PKS+terpene	100%

BGC0001729 - Region 1 - T1PKS

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Location: 1 - 47,451 nt. (total: 47,451 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 47,452
Label		BGC0001729

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001729	0.91	Polyketide, Terpene	paraherquonin	Penicillium brasilianum
BGC0001219	0.35	Polyketide	shanorellin	Chaetomium globosum CBS 148.51
BGC0002619	0.34	Polyketide	mycophenolic acid	Penicillium brevicompactum
BGC0000104	0.34	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0000687	0.33	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0001360	0.32	Polyketide	mycophenolic acid	Penicillium roqueforti FM164
BGC0001924	0.32	Terpene	ascofuranone	Acremonium egyptiacum
BGC0002181	0.30	Terpene	pleuromutilin	Rhodocybe pseudopiperita
BGC0001677	0.29	Polyketide	mycophenolic acid	Penicillium roqueforti
BGC0002616	0.29	Polyketide	mycophenolic acid	Penicillium roqueforti

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001729	1.00	Polyketide, Terpene	paraherquonin	Penicillium brasilianum
BGC0002181	0.70	Terpene	pleuromutilin	Rhodocybe pseudopiperita
BGC0001219	0.68	Polyketide	shanorellin	Chaetomium globosum CBS 148.51
BGC0001893	0.68	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002619	0.67	Polyketide	mycophenolic acid	Penicillium brevicompactum
BGC0000104	0.67	Polyketide, Terpene	mycophenolic acid	Penicillium brevicompactum
BGC0000687	0.66	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0002245	0.66	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0001528	0.66	Terpene	betaestacin	Phoma betae
BGC0001360	0.66	Polyketide	mycophenolic acid	Penicillium roqueforti FM164

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 9561 - 47451:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

prhL

PKS_AT (910..1195): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 69.1
inactive: 44.8
Methoxymalonyl-CoA: 44.6
Methylmalonyl-CoA: 29.7
Ethylmalonyl-CoA: 21.7
Benzoyl-CoA: 20.8
Propionyl-CoA: 15.2
fatty_acid: 13.3
2-Methylbutyryl-CoA: 12.7
CHC-CoA: 12.6
Isobutyryl-CoA: 8.5
3-Methylbutyryl-CoA: 4.9
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0