BGC0001742: piericidin A1 biosynthetic gene cluster from Candidatus Streptomyces philanthi bv. triangulum
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Location: 1 - 50,415 nt. (total: 50,415 nt).
This entry is originally from NCBI GenBank KX098584.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001742
Short description piericidin A1 biosynthetic gene cluster from Candidatus Streptomyces philanthi bv. triangulum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KX098584.1
via
Compounds
  • piericidin A1
Species Candidatus Streptomyces philanthi bv. triangulum [taxonomy]
References
Chemical products information
piericidin A1 Evidence:
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C25H37N1O4
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CSP_7469
  • ARV85759.1
  • pieR
 1 - 651 (+) PieR transcriptional regulator
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    • CSP_7468
    • ARV85760.1
    • pieA1
    		 1091 - 9112 (+) PieA1 type I PKS
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      • CSP_7467
      • ARV85761.1
      • pieA2
      		 9143 - 19498 (+) PieA2 type I PKS
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        • CSP_7466
        • ARV85762.1
        • pieA3
        		 19443 - 24881 (+) PieA3 type I PKS
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          • CSP_7464
          • ARV85763.1
          • pieA4
          		 24967 - 31428 (+) PieA4 type I PKS
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            • CSP_7463
            • ARV85764.1
            • pieA5
            		 31454 - 37222 (+) PieA5 type I PKS
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              • CSP_7462
              • ARV85765.1
              • pieA6
              		 37300 - 44469 (+) PieA6 type I PKS
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                • CSP_7461
                • ARV85766.1
                • pieB1
                		 44561 - 45250 (+) methyltransferase
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                  • CSP_7460
                  • ARV85767.1
                  • pieC
                  		 45394 - 45906 (+) polyketide cyclase/dehydrotase
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                    • CSP_7459
                    • ARV85768.1
                    • pieD
                    		 45981 - 47822 (+) asparagine synthase-like protein
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                      • CSP_7458
                      • ARV85769.1
                      • pieB2
                      		 47836 - 48609 (+) methyltransferase
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                        • CSP_7457
                        • ARV85770.1
                        • pieE
                        		 48606 - 50414 (+) FAD-binding monooxygenase
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                          Biosynthesis information
                          Annotation changelog

                          Entry version: 4

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-10-07
                          Update chemical activity to schema version 2.11
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Updated bioactivity data
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2019-10-16
                          Migrated from v1.4
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2018-08-06
                          Submitted
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Detailed domain annotation
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