BGC0001749 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001749 (Pyricularia oryzae 70-15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	54,985	epipyriculol	PKS	100%

BGC0001749 - Region 1 - T1PKS

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Location: 1 - 54,985 nt. (total: 54,985 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 54,986
Label		BGC0001749

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001749	0.95	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002266	0.28	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0001124	0.28	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002228	0.27	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0001141	0.26	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0002731	0.26	Polyketide	nanangenine A, nanangenine B, nanangenine C	Aspergillus nanangensis
BGC0002227	0.25	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002180	0.25	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0000894	0.24	Other	citrinin	Monascus aurantiacus
BGC0001340	0.24	Polyketide	byssochlamic acid	Byssochlamys fulva

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001749	1.00	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002266	0.61	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0001124	0.61	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002731	0.61	Polyketide	nanangenine A, nanangenine B, nanangenine C	Aspergillus nanangensis
BGC0002228	0.61	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0001141	0.60	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0002227	0.59	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002180	0.58	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0000894	0.58	Other	citrinin	Monascus aurantiacus
BGC0001067	0.58	Polyketide, Terpene	fumagillin, β-trans-bergamotene, fumagillol	Aspergillus fumigatus Af293

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 4780 - 52566:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

MGG_10912

PKS_AT (608..923): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 60.4
Methoxymalonyl-CoA: 52.0
Malonyl-CoA: 47.0
Propionyl-CoA: 19.9
Benzoyl-CoA: 19.9
fatty_acid: 11.4
Isobutyryl-CoA: 10.8
CHC-CoA: 8.5
2-Methylbutyryl-CoA: 3.8
trans-1,2-CPDA: 0.0
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -2.0