BGC0001750: pyrronazol B biosynthetic gene cluster from Nannocystis pusilla
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Location: 1 - 38,255 nt. (total: 38,255 nt).
This entry is originally from NCBI GenBank MF817819.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001750
Short description pyrronazol B biosynthetic gene cluster from Nannocystis pusilla
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: MF817819.1
Compounds
  • pyrronazol B
Species Nannocystis pusilla [taxonomy]
References
Chemical products information
pyrronazol B
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C17H17Cl1N2O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATG32069.1
  • pynA
 1 - 726 (-) methyltransferase
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  • ATG32070.1
  • pynB
 908 - 2050 (+) proline dehydrogenase
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  • ATG32071.1
  • pynC
 2053 - 3564 (+) proline specific adenylation domain-containing protein
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  • ATG32072.1
  • pynD
 3561 - 3815 (+) acyl carrier protein
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  • ATG32073.1
  • pynE
 3904 - 5250 (+) FADH2/O2 dependent halogenase
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  • ATG32074.1
  • pynF
 5271 - 7466 (+) putative nonfunctional polyketide synthase module
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  • ATG32075.1
  • pynG
 7463 - 13003 (+) polyketide synthase
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  • ATG32076.1
  • pynH
 13000 - 17190 (+) nonribosomal peptide synthetase
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  • ATG32077.1
  • pynI
 17301 - 23150 (+) polyketide synthase
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  • ATG32078.1
  • pynJ
 23277 - 27887 (+) polyketide synthase
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  • ATG32079.1
  • pynK
 27884 - 28651 (+) thioesterase domain
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  • ATG32080.1
  • pynL
 28648 - 29877 (+) cytochrome P450
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  • ATG32081.1
 29950 - 30531 (-) hypothetical protein
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  • ATG32082.1
 30543 - 31127 (-) hypothetical protein
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  • ATG32083.1
 31348 - 32184 (-) hypothetical protein
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  • ATG32084.1
 32376 - 33155 (-) NAD(P)H dehydrogenase
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  • ATG32085.1
 33274 - 34176 (+) LysR family transcriptional regulator
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  • ATG32086.1
 34216 - 34590 (+) putative enoyl-CoA hydratase
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  • ATG32087.1
 34775 - 35230 (-) putative polyketide cyclase
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  • ATG32088.1
 35626 - 36267 (+) glutathione S-transferase family protein
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  • ATG32089.1
 36282 - 37166 (-) AraC family transcriptional regulator
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  • ATG32090.1
 37356 - 38255 (+) AraC-type DNA-binding protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
pynC
Module ?
Specificity: proline
Evidence for specificity:
  • Feeding study
  • Mass spectrometry
  • Homology
pynH
Module ?
Specificity: serine
Evidence for specificity:
  • Feeding study
  • Mass spectrometry
  • Homology
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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