LOCUS       BGC0001753             20652 bp    DNA     linear   CON 07-DEC-2022
DEFINITION  Streptomyces globisporus subsp. globisporus strain NRRL B-2709
            contig3.1, whole genome shotgun sequence.
ACCESSION   BGC0001753
VERSION     BGC0001753
KEYWORDS    .
SOURCE      Streptomyces globisporus subsp. globisporus
  ORGANISM  Streptomyces globisporus subsp. globisporus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            JNZK01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:12:35
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..726
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510598.1"
                     /locus_tag="IF53_RS0104130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trypsin-like serine protease"
                     /protein_id="WP_030578055.1"
                     /transl_table=11
                     /translation="MRISRLMPAVAAAAACVLSLFAPSATAAPAPPLQDAPPPTTQIIG
                     GGYAQNAPWAARLFSNGRETCSATIIAPTWILTAKHCVTGGGLSFRIGSLDQHSGGVVA
                     NGAQTYTHSSDLALVRLDRSVQATYSRLGSPGSVSVGQSVQVWGWGATSQCGSEANCQS
                     RYLKVANVTVTGGCGDAYGGSAICARRGNGITAGGDSGGPMTANGIQVGVASTSDRQTT
                     TAYTNVTAYRSWIQSVAGV"
     protocluster    1..20652
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4413:20652]"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4414..20652
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /neighbourhood="10000"
                     /product="thiopeptide"
                     /protocluster_number="1"
     cand_cluster    1..20652
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((YcaO or TIGR03604) and ((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or PF07366 or PF06968 or PF04055) or
                     thiostrepton)"
                     /kind="single"
                     /product="thiopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..20652
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001753"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..20652
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="thiopeptide"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and ((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or PF07366 or PF06968 or PF04055) or thiostrepton)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..726
                     /locus_tag="IF53_RS0104130"
     gene            complement(902..1705)
                     /gene="nshR"
                     /locus_tag="IF53_RS0104135"
     CDS             complement(902..1705)
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="nshR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045534.1"
                     /locus_tag="IF53_RS0104135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NshR/TsnR family 23S rRNA methyltransferase"
                     /protein_id="WP_030578058.1"
                     /transl_table=11
                     /translation="MSSLDLITERSDPAVQRIIDVTKHSRAVVKTVLIEDIEPLLQSIR
                     AGVGFIEIYGLDTVTLPDELLDLCARRDIPVRLLAAPVANQVFKTEKKPKVFGLARVPK
                     PTRLADLSATTGDLILLDGVKIVGNIGAIVRTSFALGASGIVLVDSDLGTIADRRLIRA
                     SRGYVFSLPIVLASRDEALKYVQDNGVRPVVFEAGGELTVGDLDGMDERLVLMFGSERT
                     GPSGVFAHTAATSVSIPMNPAAESLNVSVSAGIALNARARRNLGR"
     gene            complement(1778..2977)
                     /locus_tag="IF53_RS0104140"
     CDS             complement(1778..2977)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA];
                     GO:0005506 - iron ion binding [Evidence IEA]; GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 418.2; E-value:
                     5.1e-127)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576487.1"
                     /locus_tag="IF53_RS0104140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_030578062.1"
                     /sec_met_domain="p450 (E-value: 6.7e-37, bitscore: 117.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSVADTWGIHEAQFWLRGQAPEAPVRFDPQAGLWCIFGYREVQQ
                     VFSDPATFSSNTQRLVPPEMREGADRFSEGNLIQMDAMEHKKLRGLISHAFTPKVVADM
                     EPRIAALTHELLDAVADGGRMELVNDLAYPLPVIVIAELLGVPASDRDKFRDWGTALME
                     STQEFSFVDRTEEQSRRLQEAMQQVGKLSDYLREHVLDRRKNPRDDLITKLVQAEVDGE
                     RLTDNEVVNFSNVLLIAGHITTTMLLGNSILCLDSHPEWLARVRADRALVPAAIEESLR
                     YYSPFAGTARATTVDVELGGERIPADSLVVTFLGVANRDPKVFTDPDTFDPLRDPNPHM
                     AFGRGAHFCIGAPLARLEGRVALNILLDRFPNLRSDPDRPPRFLPSLSMTGPEELPLVF
                     "
     gene            complement(3162..3794)
                     /locus_tag="IF53_RS0104145"
     CDS             complement(3162..3794)
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 134.4; E-value: 8e-41)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605030.1"
                     /locus_tag="IF53_RS0104145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_030578065.1"
                     /transl_table=11
                     /translation="MTDVARENERLRRLWKEYAPRYDNDMVRLERMLLDDGRAWACGQA
                     KGDVLEVAIGSGRNMEFYPDGIAVTGIDLSPEMLDLARSRASELGREVTLQEADAHAMP
                     FEDDTFDTVVCTLGLCSVPDHRKVIDEMYRVLRPGGRLVLLDHVGSHIRLIRWWQRALE
                     KAMLRQCGDHQTRRPYPLVKEAGFLVEHRDRRKLGCVERVAARKPVA"
     gene            4414..5586
                     /locus_tag="IF53_RS0104150"
     CDS             4414..5586
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451546.1"
                     /locus_tag="IF53_RS0104150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcaO-like family protein"
                     /protein_id="WP_199814150.1"
                     /sec_met_domain="YcaO (E-value: 2.1e-62, bitscore: 201.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 2.1e-103, bitscore:
                     336.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSWSGSGDTGNLDGAGSDLTGERARLISIAEALERYSICSWHDT
                     DLLTAAENDLDQGCVSPTRWPVCSANEFAQDDCGLVPYDPAVPIRWVRAWSLTRRRAVL
                     VPAIAVYLHMTPQSPSERFTRGITTGAAVHSDLRSAVLGGLLEVVERDALTLAWLQRLR
                     LPQIEVDPELLEPSARACHTAGARRHLEVRLFDATTDFGIPVVYAVQLSPHEEQLAQIV
                     GATCDIDPERAVGKLHRELASVRVALRAGLATGPAQRPEDGKVSVVGSAAYNASAERRH
                     VFAHLLEGERERRSLGELPDLSAETDPLATAVSRLAARGAETLVVDITTDEARQVGMHA
                     VKVLVPEAMPLSFIHSERYLGTPRLYDAPTAMGYESSSEQSLNPEPQPAA"
     gene            5607..6212
                     /locus_tag="IF53_RS0104155"
     CDS             5607..6212
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605028.1"
                     /locus_tag="IF53_RS0104155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030578072.1"
                     /transl_table=11
                     /translation="MSQTLADCLYLVRDTFGEQYARAYRPASWSRVTGSRLPDDARLSS
                     ASMIVAVHSGKDEKLRDELDRLGFERSIPTVGVELLPTRIVCGPAVIPGATACYSCHLR
                     RAEQHQDPARTGDLGAATRGLPEGFGPMHLAIAHGLLNLATAELRTGPAGLGATVRTFD
                     LVAGTVATAVTVAVDRCTRCGARWGGRREGADALARLV"
     gene            6256..7869
                     /locus_tag="IF53_RS0104160"
     CDS             6256..7869
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605027.1"
                     /locus_tag="IF53_RS0104160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tpaE"
                     /protein_id="WP_030578075.1"
                     /transl_table=11
                     /translation="MGVELKAEALGRAAGRDKQIAVPQRPVLRRGVRLRSAGESLMLDG
                     ADKRQAFTGRFAREDLGRLVEACDGATTLPGIAARTGLSEGTVLKSLALLWASGALEEG
                     GGNETAAAVTPELACLLSRLGNSTGVNPSWTDAAARLGRTTVHLAGDKTLAKATADCLD
                     GVCEVAGDLDELPVDGNCLVLFFETRDSLPERTALWRRCWLERRPLLRIRVDDTSMTLG
                     PYVDPAFTPCLECGVADEGDAPPDGPPDQAHDLVAGMAAHHVLALSSRSIRTCLPLDAG
                     IVDLTTLATRYRPSTTRPGCPTCSFSKGPTATTPPASAVYEASIALPVRTFLDTNGHLA
                     HFHSKNMNLQWQFRDWPSCPRVPLPAADVSRLAGTPSPTADPAECGRADLALMLAVAFG
                     IRRRSDGWVQRWTAAGGNIGSATAYVVSRDESVLPVGGYAYREGDHDLARLTDEALPGD
                     EPLLLVVTANLPKMGSKYGTFGLRISFCDGGVALAAARKVADRLNLPRSLVTDWDDRAL
                     SEYLGLSPTEEPITAVMEVG"
     gene            7873..8571
                     /locus_tag="IF53_RS0104165"
     CDS             7873..8571
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605026.1"
                     /locus_tag="IF53_RS0104165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tpaF"
                     /protein_id="WP_030578078.1"
                     /transl_table=11
                     /translation="MRTDPSMMEPLLETFADRARCGDGLAAERSLLPFADAVPVDAEAG
                     TTESGRTLDLHDTLQARRSSLQYGEAPVRTDLILRWTREALERDAGDWGLDDACGPLEA
                     FVFALRSEGRPAGVYRVTARDISFIAPASDVGDPQLLGIQREFADGAGIVTVCANLDSA
                     DAWAGSHGFRLSAVRASMALYDFHLRCQSDGLAGTVFGGFIGAAVRNLIQSDGVTRQPL
                     LSATYAHPAS"
     gene            8600..10348
                     /locus_tag="IF53_RS01000000134015"
     CDS             8600..10348
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="IF53_RS01000000134015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_032764973.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 1.5e-15,
                     bitscore: 47.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSGGLTPAGRILLTRPDVSTLRTKHGAWVGVATSSFTVKGGSAH
                     QVVSALLSRSDGSRTDHELLEEFPARSRPAVARILDALVARRCVTVLDAPLSQQTDARG
                     AASQWLIPYLSQLTDQPVRALDRLRATSLHLHGRPAWLDRLRRLLEEVPLCGLETEFHP
                     VSAEGTGAAPRWENAGLVVIDADGLPYEHTLRLQDALLERGVPHGIVGEVHGRRWILWS
                     DASTTGCWECLCGYGRTQAPSPGPSSPAAAAPAGPASLAVDDAAAAALIHAVHLRGAGL
                     GGRPEAAAAVSMPLTTDVPTVQTHPAWAAAGCRCRRAVPPPDTDAVGDDPGEVLVRRNI
                     VSPEDDSRLDDVHERIIDTLRGWTDEFIGPFRYLDGGDLPQVPFGRARSTSLVGLAGAC
                     RVHELTTATLSSREAIYQAALNTLEGYAPPGAAAGWSLNEALYRALLKRSLARPADTIT
                     WTPLTEDDLGHDECAGYGRYIRRAVTLGTEVWEWTGARLEDGVHRVTGRTGGRPEVRGA
                     GACYAEAVSMALLGLVNDEDAAVLLNPHFRTWPQVWQHLDRPTYTEVTAHTVPFAQGKA
                     RLVEVR"
     gene            10345..12243
                     /locus_tag="IF53_RS0104175"
     CDS             10345..12243
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605024.1"
                     /locus_tag="IF53_RS0104175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcaO-like family protein"
                     /protein_id="WP_234313350.1"
                     /sec_met_domain="YcaO (E-value: 3.3e-63, bitscore: 204.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 5e-79, bitscore:
                     256.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSARPQTAPPATGLMGPRAADFVSALSAAPGTPPPAEVLLGPLTA
                     PVRVHTAGNGSGRGLAVLQWCGSVHVLVHDLAHAGDGGCPQCLAWFLSRSVDSAQLPYE
                     AMSAAGGGPGAAHGDAFWQQLGPALRAAVTRLAVLLLRAPSPGGALATIDRASGAVRRG
                     NVPPRTGCPVRTATATTTIDFGAVPELLEKSEGSLRARRPLPTTLTADYLGPHSMFREP
                     LFDLDGPLPQAQVGLPLGNGMLEPGIGRSLSFNKSRTTAVLEGLERHAGFCHQRVEGTV
                     EATLAELGEQGLDPRTLGQHSPEQYAREGFLWAPLEPDERVEWVPLTPLGDGPARYLPE
                     VALSWVRRIGARQPFFYDTSNGFALGQSHEEATLHGLFEIVERDAFLLTWYRKLLLPEL
                     VLGPGDSHLKSLMDRVEVVTGFRVRLFWATQDIDVPVLLALAQRDAETGPCTLVSTATS
                     LYPRAAAESAIFEVSARVASLRHVFDKDPAHRERLAEDFDTLVEMDDHSLLGALPSSRE
                     WYAFLDTPDRPELSLTELAASAPAFGTLDKDLDHVRARIEATGAHAYAADVTTPELRWR
                     GLVCTRSFVPGCVPMTFGHGTRRLEGLPRLHDGSLPCASLLPDDMTPASVPPHPFA"
     gene            12350..14932
                     /locus_tag="IF53_RS0104180"
     CDS             12350..14932
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     89.8; E-value: 1.6e-27)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605023.1"
                     /locus_tag="IF53_RS0104180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_234313351.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.6e-42, bitscore:
                     135.6, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEDLRFDGPWARIEESRLLEEECARRAGEVSELLAALVPRVD
                     ASARAELVRLRRDVFNRRAESAARRLDLAKPHLDADTLAAVQEWLDLVGRARRSEEEAQ
                     AAFEDRMRVARDGFARVLDHDSMARSIQLSGDQLYESLRRYTSGEMGQVKPSRARVLES
                     SLVNFAYRAALKPSPFGRFTEVGAFPPDLPQAAGAVAESRTHSTATLNRVLVNWLAAGV
                     RRVEGGIDLCKVLLNSSLRVDENRIEFIGLIPDSSEHGLSESIVRLKRDKVVDCLLNVL
                     SSGTATVPEVLAALTRLTGSDATSRKALRAMMRIELLYVSPGFDEQAPDYSERFAEVLR
                     AGTTEPVSVLSGHLDTLRKLETQLSDAPVQQRGLLLSAAGEALTDISEVCEMDPPPADI
                     SRAPVYEDLWTPDRPATWSRPAVTDAVPALESLWKLSSLLDYGHTKRLGVYHFASTVFG
                     ERETVPFVAFCEQLVKLSEPEQDAVFWGHGSPEATNFVAQRTRALTELGRQCVAEDGVV
                     RLSPEAVAAACAGVEDCLDPDSITFRVQFAGGGPSPEVVVNGVLTGFGVYFSRFASFVE
                     GSPAEDWTLRNAVRDHLRKAFPGQVDLNMVAGLNFNLHPPLTDRVLNYPGTWPTAPEQK
                     AYSLDTLAIRIDHANRNLLLWDPERDERVHLAPMNFLLPVVVPVLYNLVEVLSPTIRYN
                     YAPMDDIGRAMGHQGYPGSSPRLMVGDVVASRRTWTVPARDIPELSELSKDSYPALLRF
                     DRWRRAQGLPRHVFVLTQRLDEYNLLSGLVEEIPRDWADFSHLHRASVHKPMYVDFRNP
                     YLVRSFAKSALTRDDVYVSIRECIPAPDEYGGPGPAAAEEFFVELYRD"
     gene            14913..15875
                     /locus_tag="IF53_RS0104185"
     CDS             14913..15875
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605022.1"
                     /locus_tag="IF53_RS0104185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_078651954.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.6e-57, bitscore:
                     184.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTGTERTRAGEWSPLHIYLPMSLQPGFLRDVIRPVVHEAGVQD
                     HFWYLRYWQGGPHIRFRLHDASEQMVESVRDRLAAAMPAFDAEQRAEYAQQSSHQPGLA
                     ELEGAEPEEVRAAGTVEPAVYTPESAKYGGETGLRIAEELFRSTSNAALDLLAGLSDRQ
                     LASSPTGQALRVMAMSLKGSGLDVVQSQDFLGHYEEDWRRWVPPGYDENWPKIYGRTRM
                     KVVELCRAVWIDGSTDVFYDIYTQAWRSARKAQSGAADGDVAELVLEGTPYAHCLANYI
                     HTTNNRLGILPVAEAFLAYVIRRALSELQSGDPSNTNGA"
     gene            15987..16142
                     /locus_tag="IF53_RS1000000135460"
     CDS             15987..16142
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thiostrepton"
                     /gene_functions="biosynthetic-additional (thiopeptides)
                     predicted thiopeptide"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605021.1"
                     /locus_tag="IF53_RS1000000135460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiocillin/thiostrepton family thiazolyl peptide"
                     /protein_id="WP_078651955.1"
                     /sec_met_domain="thiostrepton (E-value: 1.9e-08, bitscore:
                     24.6, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAVESLDLNALEISDLIEDSNYSDETLSQAMAASTTTTGCTTSS
                     CSSSSS"
     CDS_motif       15987..16088
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MDAVESLDLNALEISDLIEDSNYSDETLSQAMAA"
                     /locus_tag="IF53_RS1000000135460_thiopeptide"
                     /aSTool="thiopeptides"
                     /tool="antismash"
     CDS_motif       16089..16142
                     /prepeptide="core"
                     /locus_tag="IF53_RS1000000135460_thiopeptide"
                     /peptide="thiopeptide"
                     /predicted_class="Type III"
                     /score="11.70"
                     /molecular_weight="1584.6"
                     /monoisotopic_mass="1583.6"
                     /core_sequence="STTTTGCTTSSCSSSSS"
                     /aSTool="thiopeptides"
                     /tool="antismash"
                     /leader_sequence="MDAVESLDLNALEISDLIEDSNYSDETLSQAMAA"
                     /leader_location="[15986:16088](+)"
                     /alternative_weights="1602.6"
                     /alternative_weights="1620.6"
                     /alternative_weights="1638.7"
                     /alternative_weights="1656.7"
                     /alternative_weights="1674.7"
                     /alternative_weights="1692.7"
                     /alternative_weights="1710.7"
                     /alternative_weights="1728.8"
                     /alternative_weights="1746.8"
                     /alternative_weights="1764.8"
                     /alternative_weights="1782.8"
                     /alternative_weights="1800.8"
                     /alternative_weights="1818.9"
                     /alternative_weights="1836.9"
     gene            16242..16394
                     /locus_tag="IF53_RS1000000135465"
     CDS             16242..16394
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thiostrepton"
                     /gene_functions="biosynthetic-additional (thiopeptides)
                     predicted thiopeptide"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605021.1"
                     /locus_tag="IF53_RS1000000135465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiocillin/thiostrepton family thiazolyl peptide"
                     /protein_id="WP_078651956.1"
                     /sec_met_domain="thiostrepton (E-value: 8.6e-11, bitscore:
                     32.2, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSSEELDLNALEISDLIDELGRDNETLSQVMAASCVGTACACSS
                     TSSSS"
     CDS_motif       16242..16343
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNSSEELDLNALEISDLIDELGRDNETLSQVMAA"
                     /locus_tag="IF53_RS1000000135465_thiopeptide"
                     /aSTool="thiopeptides"
                     /tool="antismash"
     CDS_motif       16344..16394
                     /prepeptide="core"
                     /locus_tag="IF53_RS1000000135465_thiopeptide"
                     /peptide="thiopeptide"
                     /predicted_class="Type III"
                     /score="21.40"
                     /molecular_weight="1437.5"
                     /monoisotopic_mass="1436.5"
                     /core_sequence="SCVGTACACSSTSSSS"
                     /aSTool="thiopeptides"
                     /tool="antismash"
                     /leader_sequence="MNSSEELDLNALEISDLIDELGRDNETLSQVMAA"
                     /leader_location="[16241:16343](+)"
                     /alternative_weights="1455.6"
                     /alternative_weights="1473.6"
                     /alternative_weights="1491.6"
                     /alternative_weights="1509.6"
                     /alternative_weights="1527.6"
                     /alternative_weights="1545.7"
                     /alternative_weights="1563.7"
                     /alternative_weights="1581.7"
                     /alternative_weights="1599.7"
     gene            16507..17607
                     /locus_tag="IF53_RS0104200"
     CDS             16507..17607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605020.1"
                     /locus_tag="IF53_RS0104200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030578091.1"
                     /transl_table=11
                     /translation="MHVFVTIPLDRGDAALSRNIRGLLTDLFGPRRPPWPGDHYAVRTW
                     DRAGGADCLQVSLQSDTAGADAARDRVRRVTDARGLPSTVTEVPFEAIPSPLWNSGIGG
                     DGFDAAAKALYRSVTPVLVRSVSAIGDDTARAYTLALELMVANAAATVRESEQRQVSSL
                     GFGELLSLRMLSYRSHYEGAKNAMAKDPDAFERRCAAYYDKLGPHARDLISGCAASPDA
                     ATGGEPAQSWSAVVHKHFAALREESRAGRITHSGPTLDDFNENHDDGMSPSSFHAQKLS
                     AEMSDLLHRSPDFLAYRIQASLLYSCLHTMGFGLAERYLFCYILARANEEVAGRTTEEL
                     AQGLDAVAQEMAAQQGATTHRLMQAP"
     gene            17657..19621
                     /locus_tag="IF53_RS0104205"
     CDS             17657..19621
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03975"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 153.9; E-value: 9.7e-47)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605019.1"
                     /locus_tag="IF53_RS0104205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_030578095.1"
                     /sec_met_domain="TIGR03975 (E-value: 2.1e-178, bitscore:
                     584.6, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITLVNVPWSPIGFPSVALGLLKSLTLKEFPEADVDVVYGNLDF
                     VDWITKRVPEFNYEDYRYYDLESCYIGTGDWVFSSALYHDPQWKVPEFLKEFGPQSDAD
                     GQNLAHGTNEERRMQTTLWLHEHVEEFTDELARRIVAGNPEVVGFTTTFQTLTASMAVA
                     RRVKELAPQTLTVFGGANCEGSMGEALHRNFDFVDYVVRGEGELAWPGLLRALYEDEAS
                     FTTVPGLCWRDESATSQYNPVSKKPLPPAAMVMPHYDEYVAQFAKSHARFWLEPRLVLE
                     SSRGCWWGEKHHCTFCGLNGASMMFRSKRPEQFFNDLVTLTERHKILDVMIVDNILDMS
                     YLDSLLPRLAEADLDLRLMYEMKANMKYEQLEIIANGGVVCVQPGIESLSSKVLKLMDK
                     GVSGCLNVRVLRDAESLGLTVAWAYLYGFPGETDEDYTKIIEQFPVLHHLEPAGGDDRL
                     AVQRFAPYFENPSLGFHERWAAPQYGLTYDLPEKELFDLAYIFKATHKGIGNDLAWTLR
                     SRMNEWRDAHWYSQLSYFETDEGITLTNTRPGFDWDVVQLTTEVEIALFQMLDQPRKLD
                     YLQRECAKRFGTTDISSVIDRWMELGLLFTDDGRLIHVVTRDRNQRFMQIRVGQSLAAR
                     PEAEAPALQPAASAQSAAV"
     gene            19636..20310
                     /locus_tag="IF53_RS0104210"
     CDS             19636..20310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605018.1"
                     /locus_tag="IF53_RS0104210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5825 family protein"
                     /protein_id="WP_234313352.1"
                     /transl_table=11
                     /translation="MTTMNETAPPGNASDVRFSMWRHGARSVRVLPGMHLGDGVLGPDI
                     ADEARRIYQSGVRFVSIEPTVDLGGRVGTEHVIPMLSFIRDLTSYGVEVDWRAQLTTPD
                     GPEWWVYSHLFPPSAVEGPRGSEALRIWRARYHIGRCFYRRGPGYLQIRDRRNAGLRRL
                     TVSDEAYVSAVEALAADRGGDLVPATAMKVFEKHHLVVRIGDGVWWAPYRLRRWASPSW
                     EV"
     gene            20314..20652
                     /locus_tag="IF53_RS0104215"
     CDS             20314..20652
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thio_amide"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605017.1"
                     /locus_tag="IF53_RS0104215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030578101.1"
                     /sec_met_domain="thio_amide (E-value: 1.4e-31, bitscore:
                     98.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVSIVLWNLKDSKATVEELREYLRDYAVDAFSTLRGMRMKTWFA
                     DAEKGYWGAVYLWDGVDMQNPLSVSRAIDIIGYPPTSTSVFAVEAIAEGVSVIDSFAGV
                     GRAFEEAP"
ORIGIN
        1 atgcgcatat cccggctcat gcccgctgtc gccgcagcag cggcctgcgt cctctcgctc
       61 ttcgcaccgt ccgcgacggc cgcacccgcg ccgccgctcc aggacgcccc gccgcccacc
      121 acccagatca tcggcggcgg ttacgcccag aacgccccct gggccgcccg gctcttctcg
      181 aacggcagag agacctgttc ggcgacgatc atcgcgccga cctggatcct caccgccaag
      241 cactgcgtca ccggcggcgg cctgtcgttc cgcatcggca gcctggacca gcacagcggc
      301 ggtgtcgtcg cgaacggcgc ccagacctac acccacagct cggacctggc gctggtgcgg
      361 ctggaccgtt ccgtgcaggc gacctattcc cgcctcggct cgccgggctc ggtgagcgtc
      421 gggcagagcg tccaggtctg gggctggggc gcgacctcgc agtgcggctc ggaggcgaac
      481 tgccagtcgc gctacctgaa ggtcgccaac gtgacggtca ccggcggctg cggtgacgcg
      541 tacggcggct cggcgatctg cgcccgccgc ggcaacggca tcaccgccgg cggcgactcc
      601 ggcggtccga tgacggcgaa cggcatccag gtcggcgtcg cgtccaccag cgaccgccag
      661 accacgaccg cgtacacgaa cgtcaccgcg taccggtcct ggatccagtc ggtcgcgggc
      721 gtctgacccc ggacacgcct gaacgccccg cccgggacgg cgggcacctg accggtccgc
      781 cgtcccccga tccgtagggc ccccgtacct caccgcccga ggtatcgggg ccctacctcc
      841 atttcggggt ggggcaggcg gaagacgggc accgcgacgg ccgtgatccg gccgaccggg
      901 gctaccggcc gagattgcgg cgggcgcggg cgttcagggc gatcccggcc gagaccgaga
      961 cgttgagcga ctccgccgcg gggttcatcg ggatggagac cgacgtggcg gccgtgtgcg
     1021 cgaacacgcc cgacgggccg gtcctctcac tgccgaacat caggacgagg cgctcgtcca
     1081 tgccgtccag atcgccgacc gtgagctccc cgccggcttc gaagaccacc gggcgcacgc
     1141 cgttgtcctg gacgtacttg agcgcctcgt cccgggacgc gaggacgatg ggaagggaga
     1201 acacatagcc ccggctcgcc ctgatcagcc gtcggtcggc gatggttccg agatcgctgt
     1261 ccacgaggac gatgcccgag gcgccgaggg cgaacgaggt gcgcacgatg gcgccgatat
     1321 tgccgacgat cttcacgccg tcgaggagaa tgaggtcacc ggtcgtggcg gacaggtccg
     1381 cgaggcgggt cggcttgggg acccgggcca ggccgaagac cttcggcttc ttctccgtct
     1441 tgaagacctg gttggcgacg ggggcggcga gcagccggac cgggatgtcg cgccgggcgc
     1501 acaggtcgag cagttcgtcc ggcagggtca cggtgtcgag cccgtagatc tcgatgaacc
     1561 cgactccggc ccggatgctc tgcagcagtg gctcgatgtc ctcgatcagt accgtcttga
     1621 cgacggcccg cgagtgcttc gtgacatcga tgatgcgctg cacagcggga tcggagcgtt
     1681 ccgtgatgag gtcaaggctg gacatcggcc gaacatagca cgcggtccgg cacccgcttt
     1741 tcggtgcggg acggggcccg caccgaacgc ctgggcgtca gaacaccagc ggcagttcct
     1801 cggggccggt catgctgagg ctcggcagga accggggcgg ccggtccggg tcgctgcgca
     1861 ggttcgggaa gcggtccagc aggatgttca gcgccaccct gccctccagg cgggcgagcg
     1921 gcgcgccgat gcagaagtgc gccccccggc cgaacgccat gtgggggttc gggtcgcgca
     1981 gcgggtcgaa ggtgtcgggg tcggtgaaca ccttcgggtc gcggttcgcc acgccgagga
     2041 aggtcaccac cagggaatcg gcgggaatgc gctcaccgcc gagttccacg tcgacggtcg
     2101 tggcacgcgc cgttcccgcg aaggggctgt agtaccgcag cgactcctcg atcgcggccg
     2161 gcaccagcgc gcggtccgcg cgcacccggg cgagccactc cgggtggctg tccagacaca
     2221 ggatcgagtt gcccaacagc atcgtggtcg tgatgtgccc ggcgatcagc agcacgttgg
     2281 agaagttgac gacctcgttg tcggtgaggc gttcaccgtc cacctcggcc tgaaccagct
     2341 tggtgatgag gtcgtcgcgg gggttcttcc ggcggtcgag aacgtgttcg cgcaggtagt
     2401 cggagagttt cccgacctgc tgcatggcct cctgaaggcg tcggctctgc tcttcggtcc
     2461 ggtcgacgaa ggagaactcc tgagtgctct ccatgagcgc ggttccccag tcccggaact
     2521 tgtcccggtc cgaggccggc actccgagca gctcggcgat gacgatgacg ggaagcgggt
     2581 aggccaggtc gttgaccaat tccatacggc cgccgtcggc cacggcgtcg agcagttcgt
     2641 gggtgagggc ggcgatgcgt ggttccatat cggccaccac cttcggagtg aaggcgtggc
     2701 tgatcagtcc acggagcttc ttgtgctcca tcgcgtccat ctgaatgagg ttgccctcac
     2761 tgaaccggtc ggcgccctcc cgcatttccg gaggcacaag gcgctgggtg ttcgaggaga
     2821 acgtcgcagg atcggagaaa acctgctgta cctcccgata gccgaagatg caccagagtc
     2881 cggcctgcgg atcgaagcgc accggggctt ccggcgcctg gccgcgcagc cagaactgcg
     2941 cctcgtgaat tccccaggta tccgccacgg atgtcatgtc gtgtcatcct tcgctagagc
     3001 gtaggtttga ggtccgcgca cggaaagcgg aatcgcggga acgcggaacc atggaaacgc
     3061 ggaaacgatc ttcttgccgg tgcacgacgc ggcggtatgc cgcattccgc ggggaagcgg
     3121 gaaagggtgc cgcccggcac agggaggcag cgccgcgggc gttacgccac gggtttgcgc
     3181 gcggcgaccc gctcgacgca ccccagcttg cggcggtccc ggtgctcgac gaggaatccg
     3241 gcctccttga ccaacgggta cggccgacgg gtctggtggt ccccgcactg gcggagcatg
     3301 gccttctcca gggcgcgctg ccaccagcgg atcagccgga tgtggctgcc gacatggtcg
     3361 agcagcacca gcctcccgcc ggggcgcagc acccggtaca tctcgtcgat caccttccgg
     3421 tgatcgggca cgctgcagag cccgagggtg cagacgaccg tgtcgaacgt gtcgtcctcg
     3481 aagggcatcg cgtgggcgtc ggcctcctgg agggtgacct cgcgacccag ttcactggcc
     3541 cggctccggg ccagatcgag catctcggga ctcagatcga tgccggtcac cgcgatgccg
     3601 tccgggtaga actccatgtt ccggccgctg ccgatggcga cttcgaggac gtcccccttg
     3661 gcctggccgc atgcccacgc ccgcccgtcg tcgagcagca tgcgttccag gcgcaccatg
     3721 tcgttgtcgt agcggggcgc gtattccttc cacaggcggc gaagccgctc gttctccctg
     3781 gccacgtcgg tcacgtcgta ctccccctgc cccattcacc tcgcgcccga cctggccgaa
     3841 cgatttccat cgtggccggt ttccctgcat cgacatgcgg cgcgaggtgc ccgcggataa
     3901 gtcggattct gctcgtgcca ggagactgtg ccagaaagaa ccgtgatcgg ctagggaccg
     3961 tccgccccct ctccgagacg tccgcgcgac cccgcttcgc ggatccgcca cggtgggttc
     4021 gggcgttgcg acgggcctgt cggccgtggc cgaaatcagt ggccagagct ttcgtccggc
     4081 ggtcgaacgg catctcaagc agccgagaga acccccgctg agctgcggta attacccccg
     4141 gtcaccgaat tgccccggca gtcgatcacc ccttgacagg ctagattcct tcagcaacga
     4201 tcgacgtcgg cggccagcga tgagcccggg attaccacaa ctttggggga agagtctgtg
     4261 gataccgtga agaccgaatt gcagcggata gcgtccttgg tgtccccata cggcctcgta
     4321 tcccgtacga ccgcattacc tgtggccgat ggcgatccac gcttcgccgt ccgcgtttcc
     4381 cgaatcggtg atctctcaaa agttctgcag gggatgcgga gctggagcgg cagcggcgac
     4441 accggcaatc tcgacggcgc cggcagcgat ctgacagggg agcgggcccg gctcatctcg
     4501 atcgccgagg ccctggagcg gtactcgatc tgctcctggc acgacaccga cctcctcacc
     4561 gccgccgaga acgacctcga ccagggctgc gtgtcgccca cgaggtggcc cgtgtgctcg
     4621 gcgaacgagt tcgcccagga cgactgcggc ctcgtaccgt acgacccggc cgtcccgatc
     4681 agatgggtac gggcctggtc gctgacccgg cgccgcgccg tcctcgtacc ggccatcgcg
     4741 gtctacctgc acatgacacc gcagtcgccg tcggaacgct tcacccgagg catcaccacc
     4801 ggcgcggccg tccactccga cctccgcagc gcggtgctcg gcgggctgct ggaggtcgtg
     4861 gagagggacg cgctgaccct cgcctggctc caacgcctgc ggctgccgca gatcgaggtc
     4921 gacccggagc tgctggagcc ctccgcacgc gcctgccaca cggcgggcgc ccgacgccac
     4981 ctggaagtcc ggctcttcga cgcgacgacg gacttcggta tccccgtggt gtacgccgtc
     5041 cagctgtcgc cccacgagga acagctcgcg cagatcgtcg gcgcgacgtg cgacatcgat
     5101 ccggagcgcg ccgtgggcaa gctccaccgc gagctggcct cggtacgggt ggcgctgcgc
     5161 gccggtctgg ccaccggtcc ggcgcagcgg cccgaggacg ggaaggtcag cgtcgtcggc
     5221 tcggcggcgt acaacgcgtc ggcggagcgg cggcacgtct tcgcgcatct gctggagggc
     5281 gagcgcgagc ggcggtccct cggcgaactg cccgatctgt cggccgagac cgacccgctg
     5341 gcgaccgccg tgtcccgact ggccgcgcgc ggcgcggaaa cactcgtcgt ggacatcacc
     5401 acggacgagg cacgccaggt ggggatgcac gccgtcaagg tgctggtgcc cgaagccatg
     5461 ccgctgtcgt tcatccacag cgagcgctac ctcggcaccc cccggctcta cgacgcgccg
     5521 acggcgatgg ggtacgagag cagctcggaa cagtcactga atccggaacc gcagccggcc
     5581 gcgtagccgg cgtacaggag gagcaggtgt cccaaactct cgcggactgt ctgtacctgg
     5641 taagggacac cttcggcgaa cagtacgcgc gggcctaccg gcccgcgtcc tggagccggg
     5701 tgaccggcag ccggctcccg gacgacgccc ggctgtcgag cgcctcgatg atcgtcgccg
     5761 tgcactccgg caaggacgag aagctgcgtg acgagctcga ccggctcggg ttcgagcggt
     5821 ccatcccgac cgtcggcgtc gaactgctcc cgaccaggat cgtctgcggt ccggccgtga
     5881 tccccggggc cacggcctgc tactcctgcc atctgcgccg cgccgaacag caccaggacc
     5941 ccgcgcgcac cggtgacctg ggcgcggcga cccggggcct gcccgaaggt ttcggcccga
     6001 tgcacctcgc catcgcgcac ggcctgctga acctcgccac ggccgagctg cgtacgggcc
     6061 ccgccggact cggggcgacg gtccggacct tcgacctggt cgcggggacg gtggcgaccg
     6121 cggtgaccgt ggccgtggac cgatgtaccc ggtgcggcgc ccgatggggc ggccgacggg
     6181 agggggccga cgcactggca cgcctcgtct gagccgtttc atcacgtcat caccatgggg
     6241 gaagggacac gatcgatggg tgtggagctg aaggcagagg ccctgggacg ggccgcaggc
     6301 cgggacaaac agatcgcggt cccacaacgg cccgttctgc gcagaggtgt ccggctgcgc
     6361 agtgccggag agtccttgat gctcgacggg gccgacaagc ggcaggcctt caccggcagg
     6421 ttcgcgcgcg aggacctcgg ccggctggtc gaagcctgtg acggcgccac caccctgccc
     6481 ggtatcgccg ccaggacggg gctctccgag gggaccgtcc tcaagtcgct cgccctgctc
     6541 tgggcgtcgg gcgccctgga ggaaggcggc gggaacgaga cggccgcggc ggtcacgccc
     6601 gagctggcct gccttctgtc ccggctcggc aactccaccg gggtgaaccc gtcctggacc
     6661 gacgccgcgg cccgtctggg ccgtacgact gtgcacctgg cgggcgacaa aaccctggcg
     6721 aaggccacgg cggactgcct ggacggcgtc tgcgaggtgg ccggcgacct cgacgagctg
     6781 ccggtcgacg gcaactgcct cgtcctcttc ttcgagaccc gcgactccct ccccgaacgc
     6841 accgctctgt ggcgccgatg ttggctggaa cgaaggcccc tgctgcgcat acgcgtcgac
     6901 gacacgtcga tgaccctggg cccgtacgtg gacccggcgt tcaccccctg cctggagtgc
     6961 ggcgtcgcgg acgaggggga cgcgccgccg gacggcccgc ccgaccaggc gcacgacctg
     7021 gtcgcgggca tggccgccca ccatgtgctc gccctctcct cccgttcgat ccggacctgt
     7081 ctgccgctcg acgccggcat cgtcgatctg accaccctgg cgacccgcta ccgccccagc
     7141 accacccgcc ccgggtgccc cacctgctcg ttcagcaagg gccccacggc gaccacgccg
     7201 cccgcctccg cggtctacga ggcgtcgatc gcccttccgg tgcgcacctt cctcgacacc
     7261 aacgggcacc tggcccactt ccactcgaag aacatgaacc tccagtggca gttccgcgac
     7321 tggcccagct gcccgcgggt gccgctgccc gccgccgacg tgtcgcggct ggcggggaca
     7381 ccgtcgccga ctgcggatcc ggccgagtgc gggcgcgccg acctcgccct gatgctcgcg
     7441 gtcgccttcg gtatccgccg gcggtccgac ggctgggtgc agcggtggac ggcggccggc
     7501 ggcaacatcg gttcggccac ggcctatgtg gtgagccgcg acgagtccgt actgcccgtg
     7561 ggcgggtacg cgtaccgcga gggggaccac gacctcgccc ggctgaccga cgaggcgctg
     7621 ccgggtgatg agccgctgct gctggtcgtc accgccaacc tgccgaagat gggctccaag
     7681 tacggcacgt tcgggctccg catctccttc tgtgacggcg gcgtcgccct ggcggccgcc
     7741 cggaaggtcg ccgaccggct gaacctgccc cgctccctcg tcacggactg ggacgaccgg
     7801 gccctgagcg agtacctggg cctctccccc accgaagaac cgatcaccgc cgtcatggag
     7861 gtgggctgaa ccgtgcgcac cgacccttcc atgatggagc ccctgctgga gaccttcgcc
     7921 gaccgggccc gctgcggcga cggcctggcg gcggagcggt cgctgctgcc gttcgcggac
     7981 gccgtgcccg tcgatgcgga ggcggggacg acggagtccg gccgcaccct ggacctgcac
     8041 gacaccctcc aggcgcgtcg gtcctccctt cagtacggag aggcgcccgt acgcacggac
     8101 ctgatcctgc ggtggacgcg cgaggcgctg gagcgcgacg ccggtgactg ggggctcgac
     8161 gacgcctgcg gcccgctgga ggcgttcgtc ttcgcgctgc gcagcgaggg ccgcccggcc
     8221 ggggtctacc gcgtcaccgc gcgggacatc tcgttcatcg ccccggcctc tgacgtcggc
     8281 gaccctcaac tcctgggcat tcaaagggag ttcgcggacg gggccgggat cgtcaccgtc
     8341 tgcgccaacc tcgactccgc cgacgcgtgg gcggggtcgc acggcttccg cctcagcgcg
     8401 gtgcgtgcct cgatggccct ctacgacttc catctgcgct gccagtccga cgggctcgcc
     8461 ggcaccgtct tcggcggctt catcggcgcg gccgtccgga acctgatcca gagcgacggt
     8521 gtgacgagac agcccctgct gtccgcgacc tacgcccacc ccgcttcctg agcgccgggt
     8581 ttcgaaagtg agtgaatcga tgtcctctgg gggtctcacg ccggccgggc ggatccttct
     8641 cacccggccc gacgtctcga cgctgcggac caagcacggc gcgtgggtcg gcgtcgccac
     8701 gtcctcgttc accgtgaagg gcgggtccgc ccaccaggtc gtctcggcgc tgctgagccg
     8761 gtcggacggc agccgtaccg accacgaact gctggaggag ttcccggccc ggtcacggcc
     8821 ggcggtcgcg cgcatcctgg acgccctcgt ggcgcgccgg tgcgtgaccg tgctggacgc
     8881 accgctgtca cagcagaccg acgccagggg agccgcgtcg cagtggctga tcccgtacct
     8941 ctcgcagttg acggaccaac cggtgcgcgc gctggaccgc ctccgtgcca cctccctgca
     9001 cctccacggc cgccccgcgt ggctcgaccg gctgcgccgc ctgctggagg aggtgccgct
     9061 ctgcggcctg gagaccgagt tccacccggt ctcggccgag gggacagggg cggcgccccg
     9121 gtgggagaac gccggactgg tggtcatcga cgcggacggg ctcccgtacg agcacactct
     9181 gcgcctgcag gacgcactgc tcgaacgcgg ggttccgcac ggcatcgtgg gcgaagtgca
     9241 cggacgccgc tggatcctgt ggtccgacgc gagcacgacg ggctgctggg agtgcctgtg
     9301 cgggtacggc cgtacgcagg cgccgtcccc cggcccgtcg tccccggccg ctgccgcgcc
     9361 cgccggcccc gcctccctcg cggtggacga cgccgccgcc gctgcgctga tccacgcggt
     9421 ccacctgcgc ggcgccggac tcggcggacg cccggaggcg gccgccgccg tgtccatgcc
     9481 gctgaccacg gacgtaccga cggtacagac gcatccggca tgggccgccg cgggatgccg
     9541 ctgccgacgc gcggtgccgc cgccggacac cgacgccgtc ggcgacgacc cgggcgaggt
     9601 actggtccgc aggaacatcg tcagccccga ggacgacagc cgcctggacg acgtgcatga
     9661 gcggatcatc gacacgctgc gcgggtggac cgacgagttc atcggcccct tccggtatct
     9721 ggacggtggc gacctccccc aggtcccctt cgggcgggcc cggagcacct ccctcgtcgg
     9781 gctcgccggt gcctgccggg tccacgaact gaccaccgcc acgctgtcgt cccgcgaggc
     9841 gatctaccag gcggcgctga acacgctgga ggggtacgcg ccccccgggg cagccgccgg
     9901 ctggtcgctg aacgaagcgc tctaccgcgc cctgctgaag cgttcgctgg cccggcccgc
     9961 ggacacgatc acgtggacgc ccctgaccga ggacgacctc ggccacgacg agtgcgccgg
    10021 atacggccgg tacatccggc gggccgtcac cctcggcaca gaggtgtggg agtggaccgg
    10081 cgcccggctg gaggacggcg tccaccgggt caccggccgt accggcggcc gcccggaggt
    10141 gcggggcgcg ggagcctgct acgccgaagc ggtctccatg gcgctgctcg ggctggtcaa
    10201 cgacgaggac gccgcggttt tgctcaaccc gcacttccgc acctggccgc aggtgtggca
    10261 gcacctcgac cggcccacgt acaccgaggt cacggcgcac accgttccgt tcgcacaagg
    10321 caaggcccga ctggtggagg tccgatgagc gcccgaccgc agaccgcccc gccggccacc
    10381 gggctgatgg gcccccgtgc ggccgacttc gtctccgccc tctccgccgc ccccggcacc
    10441 ccgccgccgg cggaagtgct cctcggcccg ctgacggccc ccgtccgggt gcacacggca
    10501 gggaacggtt cgggacgcgg cctggccgta ctgcagtggt gcggaagcgt gcacgtcctg
    10561 gtccacgacc tggcacacgc gggcgacggc ggctgcccgc agtgcctggc gtggttcctc
    10621 agcaggagcg tggactccgc ccagctgccg tacgaggcga tgtccgcggc cggcggggga
    10681 cccggagccg cacacggcga cgcgttctgg caacagctcg gcccggcgct gcgcgccgcc
    10741 gtcacccggc tcgccgtact gctcctgcgg gcgccctccc ccggtggcgc gctcgccacg
    10801 atcgaccggg cgagcggcgc ggtgcggcgg ggaaacgtac ccccgcggac gggctgcccg
    10861 gtgcgcaccg ccacggcgac gacgacgatc gacttcgggg ccgtgcccga gctgctggag
    10921 aagtccgaag ggtcgctgcg ggcccggcgt ccgctgccga cgaccctcac ggccgactac
    10981 ctgggaccgc actccatgtt ccgggagccg ctcttcgacc tggacggccc actgccccag
    11041 gcccaggtgg gcctcccgct gggcaacggc atgctggaac ccggcatcgg acgcagcctg
    11101 agcttcaaca agagccggac gaccgcggtg ctcgaagggc tggagcggca cgccgggttc
    11161 tgtcaccagc gggtcgaggg caccgtggag gccacgctcg ctgaactggg cgaacagggc
    11221 ctcgatccgc gcaccctggg acagcactcg cccgagcagt acgcgcgcga gggcttcctc
    11281 tgggcccccc tggaaccgga cgagagggtg gagtgggtcc cgctcacgcc gctcggcgac
    11341 gggcccgccc ggtacctccc cgaggtcgcg ctgtcgtggg tgcgccgcat cggggcccga
    11401 cagccgttct tctacgacac gtcgaacggt ttcgcgctgg gccagagcca cgaggaagcc
    11461 acgctgcacg ggctgttcga gatcgtggag cgggacgcgt tcctgctcac ctggtaccgc
    11521 aagctgctgc tgcccgagct ggtcctgggg ccgggcgaca gccacctgaa gagcctgatg
    11581 gaccgcgtcg aggtggtgac ggggttcagg gtgcgtctct tctgggccac ccaggacatc
    11641 gacgtgcccg tgctgctggc gctcgcccag cgcgacgcgg agacgggccc ctgcaccctc
    11701 gtgtcgaccg cgaccagcct gtacccgcgg gccgcggccg agtcggcgat cttcgaagtg
    11761 tccgcccgcg tggcgtccct gcggcatgtg ttcgacaagg acccggcgca ccgggagcgg
    11821 ctcgcggagg acttcgacac gctggtcgag atggacgacc acagcctgct gggcgcgctg
    11881 ccctcgtcac gggagtggta cgcgttcctg gacacgcccg acaggcccga gctctccctg
    11941 acggaactgg ccgcctcggc accggcgttc ggcaccctcg acaaggacct cgaccatgtg
    12001 cgggcgcgga tcgaggccac cggcgcgcat gcgtacgcgg ccgacgtcac cacgcccgag
    12061 ctgcgctggc gcggtctggt ctgcacgcgg agcttcgtgc ccggctgcgt acccatgacg
    12121 ttcgggcacg gcacccgtcg gctcgaaggg ctgccgcggc tccacgacgg gtcgctgccc
    12181 tgtgcctctc tcctgcccga cgacatgact ccggcgagcg ttccgcccca cccctttgcc
    12241 tagcccgctg gtgagacgag gagtaccttt cgtgcgatcg gatgagtctg cactgaaccc
    12301 caccgcgcgg gtcagtccct atgtggtgtt ccggcgaagc cggttgcccg tggccgagct
    12361 ggaggacctg cgattcgacg ggccctgggc ccgtatcgag gagagccgcc tgctggagga
    12421 ggagtgcgcg cggcgggcgg gcgaggtgtc cgagctgctg gccgcactcg tcccgcgggt
    12481 ggacgcgtcc gcgcgggccg agctggtgcg gctgcgccgt gacgtcttca accggcgcgc
    12541 ggagtcggcg gcccggcggc tcgacctcgc caagccgcac ctcgacgcgg acacgctcgc
    12601 cgcggtacag gagtggctcg acctcgtagg gcgggcgcgg cggagcgagg aagaggcgca
    12661 ggccgcgttc gaggacagga tgcgcgtcgc ccgcgacggt ttcgcccggg tcctcgacca
    12721 cgactcgatg gcccggagca tccagctctc cggtgaccag ctgtacgaga gcctgcgccg
    12781 gtacacctcc ggcgagatgg gccaggtcaa gccgagccgg gcccgggtcc tcgaatcgtc
    12841 gctggtcaac ttcgcctacc gcgccgcgct gaaaccgtct ccgttcggcc ggttcaccga
    12901 ggtgggggcc ttcccgcccg acctgccgca ggccgcgggc gccgtggccg agtcccgtac
    12961 gcactcgacc gcaacgctga accgggtgct ggtgaactgg ctggccgccg gggtgcggcg
    13021 ggtcgagggc ggcatcgacc tgtgcaaggt gctgctgaac tcgtcgctgc gcgtggacga
    13081 gaacaggatc gagttcatcg gcctcatccc cgattcctcc gagcacggcc tctcggagtc
    13141 gatcgtgcgg ctcaagcgcg acaaggtcgt cgactgcctg ctgaacgtgc tgtcctcggg
    13201 cacggcgacg gtgccggagg tgctggccgc gctgacccgg ctgaccggca gcgacgcgac
    13261 cagccggaag gccctgcggg ccatgatgcg gatcgagctg ctgtacgtca gcccgggctt
    13321 cgacgagcag gcgccggact actccgagcg gttcgccgag gtcctgcggg ccgggacgac
    13381 cgagcccgtg tccgtcctga gcggtcatct cgacaccctc aggaagctgg agacgcagct
    13441 gtccgacgcc cccgtgcagc agcgcggact gctgctgagc gccgcggggg aggccctcac
    13501 cgacatctcg gaggtctgcg agatggaccc gccgcccgcg gacatctccc gggcgccggt
    13561 gtacgaggac ctgtggaccc cggaccggcc cgccacctgg agccggccgg ccgtgacgga
    13621 cgccgtcccg gcgctggaga gcctgtggaa gctgtcgtcg ctgctcgact acggccacac
    13681 caagcgcctg ggggtgtacc acttcgcgtc caccgtgttc ggtgagcgcg agacggttcc
    13741 cttcgtcgcc ttctgcgaac agctggtgaa gctgtcggaa cccgagcagg acgcggtgtt
    13801 ctgggggcac ggctcccccg aggcgacgaa cttcgtggca cagcgcaccc gcgccctgac
    13861 cgagctgggc cggcagtgcg tcgccgagga cggcgtggtc cggctgtctc cggaggcggt
    13921 agcggcggcg tgtgcgggtg tggaggactg cctcgacccg gactcgatca ccttccgcgt
    13981 gcagttcgcc gggggcggcc cgtcacccga ggtcgtggtg aacggcgtcc tgaccggatt
    14041 cggcgtgtac ttctcccgct tcgcgtcgtt cgtcgagggc tcccccgccg aggactggac
    14101 gctgcggaac gccgtacggg atcacctgcg caaggccttc cccggccagg tggacctcaa
    14161 catggtcgcc gggctcaact tcaatctgca cccgcccctc accgaccggg tgctgaacta
    14221 ccccggcacc tggcccacgg cgccggagca gaaggcctac agcctcgaca cgctcgcgat
    14281 ccggatcgac cacgcgaacc gcaatctgct cctgtgggac cccgagcggg acgagcgcgt
    14341 ccacctggcg ccgatgaact tcctgctccc cgtggtggtt ccggtcctct acaacctggt
    14401 cgaggtgctg agcccgacga tccggtacaa ctacgcgccg atggacgaca tcggccgggc
    14461 gatgggacac cagggctatc cgggctcgtc gccgcggctg atggtcggcg acgtggtcgc
    14521 gagccggcgc acctggacgg tgcccgcccg cgacataccc gagctgtccg agctgagcaa
    14581 ggactcctac ccggcactgc tccgcttcga ccggtggcgc cgcgcgcagg gcctgccccg
    14641 gcacgttttc gtgctgacac agcgcctgga cgagtacaac ctgctgtccg gactggtcga
    14701 ggagatcccg cgcgactggg ccgacttcag ccacctgcac cgggcgagtg tccacaagcc
    14761 catgtacgtc gacttccgca acccgtacct ggtgcgcagc ttcgccaagt ccgcgctgac
    14821 ccgggacgac gtctacgtgt ccatccggga gtgcatcccg gcacccgacg agtacggcgg
    14881 tcccggaccg gcggcagcag aggagttttt cgttgagctc tacagggact gaacgcaccc
    14941 gagccggtga gtggtcgccg ctccacatct acctgccgat gtcgctgcag cccggcttcc
    15001 tgcgggacgt gatccgtccg gtcgtccacg aggccggggt gcaggaccac ttctggtacc
    15061 tgcggtactg gcagggcggc ccgcacatca ggttccggct ccatgacgcg tcggagcaga
    15121 tggtggagtc ggtacgcgac aggctggcgg cggcgatgcc ggccttcgac gccgagcagc
    15181 gcgccgagta cgcgcagcag tcctcgcacc agcccggtct ggccgaactc gaaggggcag
    15241 aacccgagga ggtccgggcg gcgggcaccg tcgaaccggc cgtctacaca cccgagtcgg
    15301 cgaagtacgg cggggagacg ggactgcgca tcgccgagga gctcttccgc tcgacgtcga
    15361 acgcggccct cgacctcctc gccggcctgt cggaccgcca gctcgcgtcc tcgccgacgg
    15421 ggcaggccct gcgcgtcatg gccatgtccc tcaaggggtc cgggctggac gtggtgcaga
    15481 gccaggactt cctcggtcat tacgaagagg actggcgcag atgggtaccg cccgggtacg
    15541 acgagaactg gccgaagatt tacggcagga cgcgcatgaa agtggtggag ttgtgccggg
    15601 ccgtgtggat cgacggctcc accgacgttt tttacgacat ctatacacag gcgtggagat
    15661 ccgccaggaa ggcacaatcc ggagccgcgg acggcgatgt cgcggagctt gtgctggaag
    15721 gaactccgta cgcccactgc ctggccaact acatacacac caccaacaac cgcctgggga
    15781 ttctgccggt cgcggaggcg ttcctggcgt atgtcatccg tcgcgcgctc tccgaactcc
    15841 agtccggcga cccgtcgaac acgaacggag cgtagggctc cactcgtaaa ttttcgatcc
    15901 gtttgctttt tccccctacc cagctcgatt ttcctcggta cgatactcgg gtacctgaaa
    15961 cagaaaccac aaaggaggtg tttcaagtgg acgcagtgga atcgctcgac ctgaacgcgc
    16021 tggagatctc ggacctcatc gaggactcga actacagcga cgaaacgctg tctcaggcca
    16081 tggcggcgtc gaccacgacc acgggttgta cgaccagctc gtgctcgtcc tcgtcgtcct
    16141 gaccggacaa cggctgcatc gcggccgacg ggtttcattc attgaatgca cccgtcggcc
    16201 gtgaaaatcc gagagctgga aaaccgaagg aagtgtctcc tatgaattct tcagaagagc
    16261 tcgacctgaa cgctctggaa atctcggatc tgatcgacga gctgggccgc gacaacgaaa
    16321 cgctgtcgca ggtcatggcg gcatcgtgcg tgggcaccgc ctgcgcgtgc agctcgacgt
    16381 cctcgtcctc ctgacccgga gacgagaccg ctgccggcgg gggccgcgca gtacgccccc
    16441 gccggcagcg acacacccag tggtccctgc ccccggacag gtgcgtcgtg atccatggag
    16501 gtacgcatgc atgtcttcgt gacgatcccc ctcgacagag gtgacgcggc gctgtcacgg
    16561 aacatccgcg gcctcctcac cgacctcttc ggaccgcggc gaccgccctg gcccggcgac
    16621 cactacgccg tgcgcacctg ggaccgcgcc ggcggcgccg actgcctcca ggtcagcctg
    16681 cagtccgaca cggccggcgc cgacgcggca cgggaccgtg tccggcgcgt cacggacgcc
    16741 cgcggcctgc cgtccaccgt gacggaggtc cccttcgagg cgatcccttc accgctgtgg
    16801 aactccggta tcggcgggga cgggttcgac gccgccgcca aggccctgta ccgctcggtg
    16861 acgcccgttc tcgtccggag cgtgtcggcg atcggcgacg acaccgccag ggcgtacacg
    16921 ctggcactgg agctgatggt ggcgaacgcg gcggccaccg tgcgggagtc cgaacagcgg
    16981 caggtgtcct ccctcggctt cggcgaactg ctcagcctgc ggatgctcag ctatcgctcg
    17041 cactacgagg gtgcgaagaa cgcgatggcc aaggaccccg acgccttcga acgccgctgc
    17101 gccgcctact acgacaagct cggaccgcac gcccgggacc tcatcagcgg ctgcgccgcg
    17161 tccccggacg ccgcgaccgg cggggagccg gcacagtcct ggtcggctgt cgtgcacaaa
    17221 catttcgccg cgttgcgcga ggagagccgg gcgggccgca tcacccactc gggccccact
    17281 ctcgacgact tcaacgagaa ccacgacgac ggcatgtcgc ccagcagctt ccacgcgcag
    17341 aaactgtccg cggagatgtc ggacctgctg caccggagcc cggacttcct ggcgtaccga
    17401 atccaggcga gtcttctgta cagctgcctc cacacgatgg gattcgggct ggccgaacga
    17461 tacctcttct gctacatcct cgcgcgcgcc aacgaggagg tagcaggaag aactaccgaa
    17521 gagctggcgc agggactcga cgccgtcgcc caggaaatgg cagcccagca gggtgccacc
    17581 acccatcgcc tcatgcaggc accataaatc cgttgaagca accgtcaagc agagacagaa
    17641 attgcggggg cgaatcatgc gcatcacgct cgtcaacgtt ccgtggagcc cgatcgggtt
    17701 tccttcagtc gctctcggac tcctcaagag cctcactctc aaagagtttc ccgaagccga
    17761 tgtcgatgtt gtctacggaa acctcgactt cgtggactgg atcaccaaac gcgtccctga
    17821 attcaattac gaggactacc gctactacga cctcgaaagc tgctacatcg gaaccgggga
    17881 ctgggtgttc tcctcggccc tttatcacga cccgcagtgg aaggtcccgg agttcctgaa
    17941 ggagttcggc ccccagtcgg atgccgacgg gcagaatctg gcgcacggca cgaacgagga
    18001 acgccggatg cagacgacgc tctggctgca cgagcacgtc gaggaattca ccgacgaatt
    18061 ggcccgccgg atcgtcgcgg gcaaccccga ggtcgtcggc ttcacgacca ccttccagac
    18121 gctgaccgcg tcgatggcgg tggcccggcg cgtcaaggag ctcgcaccgc agacgctgac
    18181 cgtgttcggc ggcgccaact gcgaagggtc gatgggcgag gcgctgcacc gcaacttcga
    18241 cttcgtcgac tacgtggtcc gcggcgaggg cgagctggcc tggcccggcc tgctgcgcgc
    18301 gctctacgag gacgaggcgt ccttcacgac cgtacccggg ctgtgctggc gggacgagag
    18361 cgccacctcg cagtacaacc ccgtgagcaa gaagccgctg ccgccggccg cgatggtcat
    18421 gccccactac gacgagtacg tcgcgcagtt cgcgaagtcg cacgcccggt tctggctgga
    18481 gccgcgcctg gtcctggaga gctcccgcgg ctgttggtgg ggcgagaagc accactgcac
    18541 cttctgcggt ctcaacggcg ccagcatgat gttccgcagc aagcggcccg agcagttctt
    18601 caacgacctg gtgacgctca ccgaacgcca caagatcctc gacgtgatga tcgtcgacaa
    18661 catcctggac atgtcctacc tggactcgct cctcccccgg ctcgccgagg cggacctcga
    18721 ccttcgcctg atgtacgaga tgaaggcgaa catgaagtac gagcagctgg agatcatcgc
    18781 gaacggcggg gtggtctgcg tccagcccgg catcgagagc ctcagcagca aggtgctgaa
    18841 gctcatggac aagggcgtct ccggctgcct gaacgtacgc gtgctccggg acgccgagtc
    18901 gctgggcctg accgtcgcct gggcgtacct ctacggcttc cccggcgaga ccgacgagga
    18961 ctacacgaag atcatcgagc agttccccgt actgcaccac ctggagcccg ccggcggcga
    19021 cgaccggctc gccgtccagc gcttcgcccc gtacttcgag aacccctcgc tcggcttcca
    19081 cgagcggtgg gcggctccgc agtacggact cacgtacgac cttcccgaga aggaactgtt
    19141 cgacctcgcc tacatcttca aggcgacgca caagggcatc gggaacgacc tggcgtggac
    19201 gctgcgcagc cgcatgaacg agtggcgcga cgcgcactgg tacagccagc tgtcgtactt
    19261 cgagaccgat gagggcatca cgctcaccaa cacccggccg ggcttcgact gggacgtggt
    19321 ccagctcacc accgaggtcg agatcgcgct cttccagatg ctcgaccagc cgaggaagct
    19381 cgactacctc cagcgcgagt gcgcgaagcg gttcgggacc accgacatca gctccgtgat
    19441 cgaccggtgg atggagctgg gcctgctctt cacggacgac ggccgcctga tccacgtcgt
    19501 cacccgggac cgcaaccaga ggttcatgca gatccgcgtg ggccagtccc tggcggcgcg
    19561 gccggaggcc gaagcgcccg ccctgcagcc cgccgcgtcc gcccagtccg cagcagtgtg
    19621 agaggtgaag ctgtcatgac gacgatgaac gagacagcgc ccccggggaa cgcgtccgac
    19681 gtgcggttca gcatgtggcg ccacggggcc cgttcggtac gcgtcctgcc ggggatgcac
    19741 ctcggcgacg gcgtgctcgg cccggacatc gcggacgagg cccgccggat ctaccagtcg
    19801 ggcgtacggt tcgtgtcgat cgagcccacc gtcgacctcg ggggacgcgt ggggaccgag
    19861 catgtcatcc ccatgctctc cttcatccgc gacctcacca gctacggcgt ggaagtggac
    19921 tggagggcgc agctcaccac gccggacggc cccgagtggt gggtgtacag ccacctcttc
    19981 cccccgtcgg ccgtggaggg cccgcgcggc tccgaggcgc tgcgcatctg gcgggcgcgc
    20041 taccacatcg gccggtgctt ctaccgtcgc ggccccggat acctgcagat ccgcgaccgc
    20101 cgcaacgccg gtctgcgcag gctcaccgtc tccgacgaag cctatgtctc cgcggtcgag
    20161 gcactggcgg ccgaccgggg aggcgacttg gtgccggcca cggcgatgaa ggtcttcgag
    20221 aagcaccacc tggtcgtccg gatcggcgac ggcgtctggt gggcgcccta ccgtctgcgg
    20281 cgctgggcct cgccctcctg ggaggtgtga gcgttgtacg tcagtatcgt cctgtggaac
    20341 ctgaaggact ccaaggccac ggtggaagag ctccgcgagt acctgcgtga ctacgcggtg
    20401 gacgcgttct ccacgctcag ggggatgcgg atgaagacct ggttcgcgga cgccgagaag
    20461 ggctactggg gggctgtgta cctctgggac ggcgtcgaca tgcagaaccc gctgtcggtc
    20521 agccgggcca tcgacatcat cggctacccg ccgacgtcca ccagcgtctt cgcggtcgag
    20581 gccatcgcgg agggcgtcag cgtgatcgac tcgttcgccg gcgtcggccg cgccttcgaa
    20641 gaggcgccgt aa
//
