BGC0001755: reedsmycin A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 103,914 nt. (total: 103,914 nt).
This entry is originally from NCBI GenBank MG947597.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001755
Short description reedsmycin A biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MG947597.1
via
Compounds
  • reedsmycin A
  • reedsmycin B
  • reedsmycin C
  • reedsmycin D
  • reedsmycin E
Species Streptomyces sp. [taxonomy]
References
Chemical products information
reedsmycin A Evidence: NMR [1], [2]
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C36H58O10
Chemical database entries
NPAtlas
reedsmycin B Evidence: NMR [1], [2]
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C36H58O10
Chemical database entries
NPAtlas
reedsmycin C Evidence: NMR [1], [2]
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C36H58O10
Chemical database entries
NPAtlas
reedsmycin D Evidence: NMR [1], [2]
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C36H58O10
Chemical database entries
NPAtlas
reedsmycin E Evidence: NMR [1], [2]
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C36H58O10
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWW87413.1
 1 - 639 (+) TetR family transcriptional regulator
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    • AWW87414.1
    		 763 - 2016 (+) FAD-binding monooxygenase
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      • AWW87415.1
      		 2193 - 2993 (-) methyltransferase
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        • AWW87416.1
        • rdmA
        		 4531 - 5388 (+) XRE family transcriptional regulator
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          • AWW87417.1
          • rdmB
          		 5451 - 6218 (+) S-adenosyl methyltransferase
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            • AWW87418.1
            • rdmC
            		 6284 - 6937 (-) putative LuxR family two-component system response regulator
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              • AWW87419.1
              • rdmD
              		 7105 - 7437 (-) putative two-component system sensor kinase
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                • AWW87420.1
                • rdmE
                		 7488 - 8717 (-) putative two-component system sensor kinase
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                  • AWW87421.1
                  • rdmF
                  		 9852 - 10550 (+) LuxR family transcriptional regulator
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                    • AWW87422.1
                    • rdmG
                    		 11007 - 25994 (+) type I polyketide synthase
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                      • AWW87423.1
                      • rdmH
                      		 26027 - 45346 (+) type I polyketide synthase
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                        • AWW87424.1
                        • rdmI
                        		 45386 - 73984 (+) type I polyketide synthase
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                          • AWW87425.1
                          • rdmJ
                          		 74098 - 95853 (+) polyketide synthase
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                            • AWW87426.1
                            • rdmK
                            		 96225 - 97718 (+) MFS transporter
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                              • AWW87427.1
                              • rdmL
                              		 97715 - 98908 (+) Ferritin
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                                • AWW87428.1
                                • rdmM
                                		 99055 - 99570 (+) thioesterase
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                                  • AWW87429.1
                                  • rdmN
                                  		 99822 - 101549 (+) CoA ligase
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                                    • AWW87430.1
                                    		 101579 - 102106 (+) hypothetical protein
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                                      • AWW87431.1
                                      		 102166 - 102786 (-) hypothetical protein
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                                        • AWW87432.1
                                        		 102832 - 103914 (-) hypothetical protein
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: next

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2024-04-23
                                          MIBiG v4 annotathon
                                          • (ID: WO7I2Z66IEAZGQEL4YNOH36C)
                                          • (ID: YO3TP6VWB5CBNPZKNYNQSKUW)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 4

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Updated bioactivity data
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Migrated from v1.4
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2018-08-06
                                          Submitted
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
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