BGC0001760: rimosamide biosynthetic gene cluster from Streptomyces rimosus subsp. rimosus ATCC 10970
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Location: 30,040 - 59,133 nt. (total: 29,094 nt).
This entry is originally from NCBI GenBank NZ_ANSJ01000026.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001760
Short description rimosamide biosynthetic gene cluster from Streptomyces rimosus subsp. rimosus ATCC 10970
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: NZ_ANSJ01000026.1
Compounds
  • rimosamide
Species Streptomyces rimosus subsp. rimosus ATCC 10970 [taxonomy]
References
Chemical products information
rimosamide
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SRIM_RS28595
  • WP_050498799.1
 30040 - 32238 (-) FUSC family protein
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  • SRIM_RS28590
  • WP_004571773.1
 32505 - 33305 (+) hypothetical protein
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  • SRIM_RS28585
  • WP_004571774.1
 33373 - 34245 (-) TauD/TfdA family dioxygenase
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  • SRIM_RS28580
  • WP_032920603.1
 34301 - 34876 (-) hypothetical protein
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  • SRIM_RS28575
  • WP_030179607.1
 34998 - 36053 (-) GSCFA domain-containing protein
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  • SRIM_RS28570
  • WP_004571777.1
 36131 - 45430 (-) non-ribosomal peptide synthetase
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  • SRIM_RS28565
  • WP_078586793.1
 45430 - 49614 (-) non-ribosomal peptide synthetase
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  • SRIM_RS28560
  • WP_004571779.1
 50194 - 53211 (+) non-ribosomal peptide synthetase
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  • SRIM_RS28555
  • WP_004571780.1
 53230 - 54291 (-) ATP-dependent DNA ligase
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  • SRIM_RS28550
  • WP_004571781.1
 54594 - 55598 (+) non-homologous end-joining DNA ligase
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  • SRIM_RS28545
  • WP_004571782.1
 55629 - 56351 (-) hypothetical protein
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  • SRIM_RS28540
  • WP_050498798.1
 56351 - 56914 (-) SigE family RNA polymerase sigma factor
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  • SRIM_RS28535
  • WP_004571784.1
 57239 - 58048 (+) putative glycosyl hydrolase
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  • SRIM_RS28530
  • WP_004571785.1
 58192 - 59133 (+) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
SRIM_RS28570
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
Module ?
Specificity: proline
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
SRIM_RS28560
Module ?
Specificity: glycine
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
SRIM_RS28565
Module ?
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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