BGC0001768: sansalvamide biosynthetic gene cluster from [Nectria] haematococca mpVI 77-13-4
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Location: 476,075 - 504,188 nt. (total: 28,114 nt).
This entry is originally from NCBI GenBank NW_003315863.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001768
Short description sansalvamide biosynthetic gene cluster from [Nectria] haematococca mpVI 77-13-4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
NW_003315863.1
476075 - 504188
via
Compounds
  • sansalvamide
Species [Nectria] haematococca mpVI 77-13-4 [taxonomy]
References
Chemical products information
sansalvamide Evidence:
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C32H50N4O6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • NECHADRAFT_83147
  • XP_003044436.1
 476075 - 477795 (+) uncharacterized protein
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    • NECHADRAFT_45775
    • XP_003044552.1
    		 477949 - 479357 (-) uncharacterized protein
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      • NECHADRAFT_45893
      • XP_003044553.1
      		 480313 - 481098 (-) uncharacterized protein
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        • NECHADRAFT_106280
        • XP_003044554.1
        • NhNPS5
        		 483175 - 501313 (-) uncharacterized protein
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          • NECHADRAFT_45914
          • XP_003044437.1
          		 502870 - 504188 (+) uncharacterized protein
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            Biosynthesis information

            Biosynthetic modules

            Name
            Unk01
            Type
            nrps-type1
            Genes
            NhNPS5
            Substrates
            phenylalanine, leucine (evidence: Structure-based inference, Knock-out studies)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk02
            Type
            nrps-type1
            Genes
            NhNPS5
            Substrates
            leucine, phenylalanine (evidence: Structure-based inference, Knock-out studies)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk03
            Type
            nrps-type1
            Genes
            NhNPS5
            Substrates
            2S-hydroxyisocaproic acid (evidence: Structure-based inference, Knock-out studies)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk04
            Type
            nrps-type1
            Genes
            NhNPS5
            Substrates
            valine, leucine (evidence: Structure-based inference, Knock-out studies)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk05
            Type
            nrps-type1
            Genes
            NhNPS5
            Substrates
            leucine, valine (evidence: Structure-based inference, Knock-out studies)
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: 3

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Added NRP substrate specificities
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2019-10-16
            Migrated from v1.4
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2019-10-16
            Updated compound(s) information (NPAtlas curation)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2018-08-06
            Submitted
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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