BGC0001769: saquayamycin A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 44,740 nt. (total: 44,740 nt).
This entry is originally from NCBI GenBank KX356541.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001769
Short description saquayamycin A biosynthetic gene cluster from Streptomyces sp.
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KX356541.1
Compounds
  • saquayamycin A
Species Streptomyces sp. [taxonomy]
References
Chemical products information
saquayamycin A
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C43H48O16
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARO44648.1
  • sqnZ
 1 - 1605 (+) major facilitator transporter
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  • ARO44675.1
  • sqnAA
 1759 - 2499 (-) hypothetical protein
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  • ARO44659.1
  • sqnA
 2629 - 3768 (+) oxidoreductase
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  • ARO44650.1
  • sqnB
 3826 - 5406 (-) transporter
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  • ARO44679.1
  • sqnC
 5437 - 6036 (-) NADPH-dependent FMN reductase
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  • ARO44676.1
  • sqnD
 6156 - 6893 (+) TetR family transcriptional regulator
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  • ARO44670.1
  • sqnE
 7023 - 7874 (+) hypothetical protein
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  • ARO44651.1
  • sqnF
 8193 - 9680 (+) monooxygenase
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  • ARO44683.1
  • sqnBB
 9694 - 10020 (+) cyclase
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  • ARO44655.1
  • sqnH
 10044 - 11297 (+) ketoacyl synthase alpha subunit
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  • ARO44656.1
  • sqnI
 11294 - 12520 (+) ketoacyl synthase CLF
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  • ARO44684.1
  • sqnJ
 12705 - 12974 (+) acyl carrier protein
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  • ARO44671.1
  • sqnK
 13225 - 14010 (+) ketoreductase
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  • ARO44668.1
  • sqnL
 14052 - 14987 (+) cyclase
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  • ARO44645.1
  • sqnM
 14990 - 16987 (+) monooxygenase
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  • ARO44657.1
  • sqnN
 17008 - 18222 (+) transporter
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  • ARO44654.1
  • sqnG1
 18281 - 19573 (+) glycosyltransferase
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  • ARO44658.1
  • sqnG2
 19599 - 20813 (+) glycosyltransferase
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  • ARO44680.1
  • sqnS1
 20882 - 21376 (+) NDP-hexose, 3,5-epimerase
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  • ARO44660.1
  • sqnG3
 21379 - 22509 (+) glycosyltransferase
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  • ARO44662.1
  • sqnS2
 22535 - 23602 (+) glucose-1-phosphate thymidylyltransferase
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  • ARO44664.1
  • sqnS3
 23599 - 24582 (+) NDP-glucose 4,6-dehydratase
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  • ARO44667.1
  • sqnS4
 24680 - 25633 (+) NDP-hexose 4-ketoreductase
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  • ARO44653.1
  • sqnS5
 25630 - 26934 (+) NDP-hexose 3,4-dehydratase
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  • ARO44673.1
  • sqnS6
 26980 - 27744 (+) NDP-hexose 4-ketoreductase
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  • ARO44665.1
  • sqnO
 27809 - 28783 (+) hypothetical protein
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  • ARO44652.1
  • sqnS7
 28849 - 30249 (+) NDP-hexose 2,3-dehydratase
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  • ARO44666.1
  • sqnS8
 30246 - 31202 (+) NDP-hexose 3-ketoreductase
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  • ARO44674.1
  • sqnCC
 31199 - 31963 (+) 4'-phosphopantetheinyl transferase
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  • ARO44649.1
  • sqnP
 31978 - 33570 (+) decarboxylase
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  • ARO44678.1
  • sqnDD
 33641 - 34318 (+) hypothetical protein
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  • ARO44647.1
  • sqnQ
 34395 - 36023 (+) FAD/FMN-containing dehydrogenase
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  • ARO44681.1
  • sqnEE
 36141 - 36578 (+) hypothetical protein
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  • ARO44672.1
  • sqnR
 37134 - 37898 (-) positive regulation regulator
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  • ARO44646.1
  • sqnT
 38557 - 40383 (+) 2-oxoacid:ferredoxin oxidoreductase, alpha subunit
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  • ARO44661.1
  • sqnU
 40376 - 41455 (+) 2-oxoacid:ferredoxin oxidoreductase, beta subunit
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  • ARO44682.1
  • sqnV
 41489 - 41899 (-) transcriptional regulator
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  • ARO44669.1
  • sqnW
 41991 - 42845 (+) NAD(P)-dependent oxidoreductase
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  • ARO44663.1
  • sqnX
 42974 - 43987 (+) transporter
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  • ARO44677.1
  • sqnY
 44060 - 44740 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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