BGC0001769: saquayamycin A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 44,740 nt. (total: 44,740 nt).
This entry is originally from NCBI GenBank KX356541.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001769
Short description saquayamycin A biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KX356541.1
via
Compounds
  • saquayamycin A
Species Streptomyces sp. [taxonomy]
References
Chemical products information
saquayamycin A Evidence:
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C43H48O16
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARO44648.1
  • sqnZ
 1 - 1605 (+) major facilitator transporter
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    • ARO44675.1
    • sqnAA
    		 1759 - 2499 (-) hypothetical protein
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      • ARO44659.1
      • sqnA
      		 2629 - 3768 (+) oxidoreductase
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        • ARO44650.1
        • sqnB
        		 3826 - 5406 (-) transporter
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          • ARO44679.1
          • sqnC
          		 5437 - 6036 (-) NADPH-dependent FMN reductase
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            • ARO44676.1
            • sqnD
            		 6156 - 6893 (+) TetR family transcriptional regulator
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              • ARO44670.1
              • sqnE
              		 7023 - 7874 (+) hypothetical protein
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                • ARO44651.1
                • sqnF
                		 8193 - 9680 (+) monooxygenase
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                  • ARO44683.1
                  • sqnBB
                  		 9694 - 10020 (+) cyclase
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                    • ARO44655.1
                    • sqnH
                    		 10044 - 11297 (+) ketoacyl synthase alpha subunit
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                      • ARO44656.1
                      • sqnI
                      		 11294 - 12520 (+) ketoacyl synthase CLF
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                        • ARO44684.1
                        • sqnJ
                        		 12705 - 12974 (+) acyl carrier protein
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                          • ARO44671.1
                          • sqnK
                          		 13225 - 14010 (+) ketoreductase
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                            • ARO44668.1
                            • sqnL
                            		 14052 - 14987 (+) cyclase
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                              • ARO44645.1
                              • sqnM
                              		 14990 - 16987 (+) monooxygenase
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                                • ARO44657.1
                                • sqnN
                                		 17008 - 18222 (+) transporter
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                                  • ARO44654.1
                                  • sqnG1
                                  		 18281 - 19573 (+) glycosyltransferase
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                                    • ARO44658.1
                                    • sqnG2
                                    		 19599 - 20813 (+) glycosyltransferase
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                                      • ARO44680.1
                                      • sqnS1
                                      		 20882 - 21376 (+) NDP-hexose, 3,5-epimerase
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                                        • ARO44660.1
                                        • sqnG3
                                        		 21379 - 22509 (+) glycosyltransferase
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                                          • ARO44662.1
                                          • sqnS2
                                          		 22535 - 23602 (+) glucose-1-phosphate thymidylyltransferase
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                                            • ARO44664.1
                                            • sqnS3
                                            		 23599 - 24582 (+) NDP-glucose 4,6-dehydratase
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                                              • ARO44667.1
                                              • sqnS4
                                              		 24680 - 25633 (+) NDP-hexose 4-ketoreductase
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                                                • ARO44653.1
                                                • sqnS5
                                                		 25630 - 26934 (+) NDP-hexose 3,4-dehydratase
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                                                  • ARO44673.1
                                                  • sqnS6
                                                  		 26980 - 27744 (+) NDP-hexose 4-ketoreductase
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                                                    • ARO44665.1
                                                    • sqnO
                                                    		 27809 - 28783 (+) hypothetical protein
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                                                      • ARO44652.1
                                                      • sqnS7
                                                      		 28849 - 30249 (+) NDP-hexose 2,3-dehydratase
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                                                        • ARO44666.1
                                                        • sqnS8
                                                        		 30246 - 31202 (+) NDP-hexose 3-ketoreductase
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                                                          • ARO44674.1
                                                          • sqnCC
                                                          		 31199 - 31963 (+) 4'-phosphopantetheinyl transferase
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                                                            • ARO44649.1
                                                            • sqnP
                                                            		 31978 - 33570 (+) decarboxylase
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                                                              • ARO44678.1
                                                              • sqnDD
                                                              		 33641 - 34318 (+) hypothetical protein
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                                                                • ARO44647.1
                                                                • sqnQ
                                                                		 34395 - 36023 (+) FAD/FMN-containing dehydrogenase
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                                                                  • ARO44681.1
                                                                  • sqnEE
                                                                  		 36141 - 36578 (+) hypothetical protein
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                                                                    • ARO44672.1
                                                                    • sqnR
                                                                    		 37134 - 37898 (-) positive regulation regulator
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                                                                      • ARO44646.1
                                                                      • sqnT
                                                                      		 38557 - 40383 (+) 2-oxoacid:ferredoxin oxidoreductase, alpha subunit
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                                                                        • ARO44661.1
                                                                        • sqnU
                                                                        		 40376 - 41455 (+) 2-oxoacid:ferredoxin oxidoreductase, beta subunit
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                                                                          • ARO44682.1
                                                                          • sqnV
                                                                          		 41489 - 41899 (-) transcriptional regulator
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                                                                            • ARO44669.1
                                                                            • sqnW
                                                                            		 41991 - 42845 (+) NAD(P)-dependent oxidoreductase
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                                                                              • ARO44663.1
                                                                              • sqnX
                                                                              		 42974 - 43987 (+) transporter
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                                                                                • ARO44677.1
                                                                                • sqnY
                                                                                		 44060 - 44740 (-) hypothetical protein
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                                                                                  Biosynthesis information
                                                                                  Annotation changelog

                                                                                  Entry version: 4

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2022-10-07
                                                                                  Update chemical activity to schema version 2.11
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                  Entry version: 3

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2022-09-15
                                                                                  Updated bioactivity data
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                  Entry version: 2

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2019-10-16
                                                                                  Migrated from v1.4
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  2019-10-16
                                                                                  Updated compound(s) information (NPAtlas curation)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                  Entry version: 1

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2018-08-06
                                                                                  Submitted
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  Detailed domain annotation
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