LOCUS       BGC0001771             18478 bp    DNA     linear   CON 08-DEC-2020
DEFINITION  Streptomyces sclerotialus strain NRRL ISP-5269 contig43.1, whole
            genome shotgun sequence.
ACCESSION   BGC0001771
VERSION     BGC0001771
KEYWORDS    .
SOURCE      Streptomyces sclerotialus
  ORGANISM  Streptomyces sclerotialus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            JOBC01000043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:15:16
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..627)
                     /NRPS_PKS="Domain: ACPS (105-168). E-value: 2.2e-12. Score:
                     38.8. Matches aSDomain:
                     nrpspksdomains_IG96_RS0135470_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 169.6;
                     E-value: 1e-51)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308774.1"
                     /locus_tag="IG96_RS0135470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_037773640.1"
                     /transl_table=11
                     /translation="MWLARHRPGEAVAGADEALLDAEERERAAAFAHAADRAAYLAAHA
                     MLRRLLGAYLGIAADRVRYARERCPCCGEGHGRPSVVGAPLHFSLSRSGEFTLVAVAAT
                     AVGVDIEEIPRPDTARAVTSALHTEERQELACLPSADRLEAFTRCWARKEAYLKATGHG
                     LAEGVSHVHVGAGPRPAELDDWSLTDVTVPRRYRAACATQGRQYP"
     protocluster    1..18478
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[9380:12521]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9381..12521
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..18478
                     /SMILES="N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..18478
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001771"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..18478
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="AfsA"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..627)
                     /locus_tag="IG96_RS0135470"
     aSDomain        complement(124..312)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG96_RS0135470_ACPS.1"
                     /evalue="2.20E-12"
                     /label="IG96_RS0135470_ACPS.1"
                     /locus_tag="IG96_RS0135470"
                     /protein_end="168"
                     /protein_start="105"
                     /score="38.8"
                     /tool="antismash"
                     /translation="VGVDIEEIPRPDTARAVTSALHTEERQELACLPSADRLEAFTRCW
                     ARKEAYLKATGHGLAEGV"
     protocluster    161..11153
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5160:6153]"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      5161..6153
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     cand_cluster    161..11153
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     gene            complement(703..1863)
                     /locus_tag="IG96_RS0135475"
     CDS             complement(703..1863)
                     /codon_start=1
                     /inference="COORDINATES: protein
                     motif:HMM:NF012424.1,HMM:NF012584.1"
                     /locus_tag="IG96_RS0135475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="WP_030624999.1"
                     /transl_table=11
                     /translation="MIEITVPKLNNNDAAYDLIEWLVADGATVSKDDDLVTVETSKAAE
                     DLVSEHDGVLLHVVPAGTQVTPGTVVARVFPGEAERKAFLAEAAEAAEAGGRSGSGDSG
                     AGFILTDSARRLATELAVTDAELASLGKRIIKGSDVEEITSRRDAPAEPDESRLELSQH
                     QRAISAVVSESHRTVPASFTVVRIRTDAAEAAARAASERSGTAVGLTELLIAELAGLRR
                     TFPAFFGRYHDSGHVVLADASHIGVTVDLGSGLYIPVVRDADRKSVDEIADQLGDFRFS
                     ALRGSFRSSELTDAAITLSLNNDEDVILTQPIVFPGQTCMLSLGGTQQALDLTEDGELT
                     RTSYVYLGLAFDHRVINGREAVAFLRSLKSALEEPEQATAGPAQGS"
     gene            complement(1860..2876)
                     /locus_tag="IG96_RS0135480"
     CDS             complement(1860..2876)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110:1-deoxy-D-xylulose-5-phosphate synthase (Score:
                     299.4; E-value: 3.5e-91)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325690.1"
                     /locus_tag="IG96_RS0135480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="WP_030625001.1"
                     /transl_table=11
                     /translation="MKRNERVGENLNRALHDVMAAHDDTFLIGEDVLDPYGGAFNITKG
                     LSDRFGDRVLTTPISENAILGIANGLALTGNKPIAEMMFGDFITLAFDQIVNFSAKSVA
                     MYGRQHPMHLVVRCPVGGRRGYGPTHSQSPQKHFLGVPDLHLFELSPFHDNTAVLNGMI
                     ELGKPSIFFEDKVLYTERRHQEGLVADLFTLEFVGEGPFPTARLSIDGIGDPELVLIAP
                     GGLAGRAVEAARELFLSHEIACAVYVPSALYPFDVSVLADPVARAGRVCVVEDAPPGGS
                     WGAEVAHQLYSHCWQSLRAPVRLVHSADSVIPTALHLERDVVVSSRSVGSALRELVR"
     gene            complement(2873..3796)
                     /locus_tag="IG96_RS0135485"
     CDS             complement(2873..3796)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151925.1"
                     /locus_tag="IG96_RS0135485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine pyrophosphate-dependent dehydrogenase E1
                     component subunit alpha"
                     /protein_id="WP_078889003.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 4.8e-08,
                     bitscore: 22.6, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-07, bitscore:
                     21.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITAQAPPELRALDDEDLESLLLVRHFERKLLDLFAAGKLNGTT
                     HTCLGQEYVPVSLNPLLAEDDFVFSNHRGHGHYLARFADPAGLLAEITGREGAVCGGVG
                     GSQHIFRGSYLSTGIQGESLPVAAGAALHFKRNELPLLAAVYIGDGTWGEGSVYEALNI
                     AQLWELPLLVVVENNGISQTTPSAANMAGTVRGRAEAFGVGYHRVTTHDIHRIRAELAP
                     EIERVRHQHQPLVVEFETVRLGPHSKGDDTRPAEVVERARQRDWYGGYRAADPERFDRH
                     DHKVRELIDLVAADVLERPLVSGGVA"
     gene            complement(3793..4023)
                     /locus_tag="IG96_RS0135490"
     CDS             complement(3793..4023)
                     /NRPS_PKS="Domain: PP-binding (1-64). E-value: 4.6e-07.
                     Score: 22.2. Matches aSDomain:
                     nrpspksdomains_IG96_RS0135490_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.1"
                     /locus_tag="IG96_RS0135490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_030625009.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-07, bitscore:
                     22.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLEEVVSDVIQIPVGEVDDNLGPVRDARWTSLKQMQLIIALEER
                     YGTSFSRQDVRAMKTVGAVREVLRSKGVSAA"
     aSDomain        complement(3832..4020)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG96_RS0135490_PP-binding.1"
                     /evalue="4.60E-07"
                     /label="IG96_RS0135490_PP-binding.1"
                     /locus_tag="IG96_RS0135490"
                     /protein_end="64"
                     /protein_start="1"
                     /score="22.2"
                     /tool="antismash"
                     /translation="KLEEVVSDVIQIPVGEVDDNLGPVRDARWTSLKQMQLIIALEERY
                     GTSFSRQDVRAMKTVGAV"
     gene            complement(4213..4845)
                     /locus_tag="IG96_RS0135495"
     CDS             complement(4213..4845)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 91.2; E-value: 1.8e-27)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035379.1"
                     /locus_tag="IG96_RS0135495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_078889004.1"
                     /transl_table=11
                     /translation="MDSKAATHGPVAHSRREPKQERARQTKRLVLRTAAEAFKEHGYPA
                     VTLQAVAERASMTKGAVYFHYANKEALAVAVIMEHYARWEPLVSEVRSRGLPPLETLLA
                     VLEGAAEAFRDDVMVQAGARLQIERSLIKADLPVPYVGWQELLTSLITEARDAGQLRAD
                     VDPAALARVVVAAFFGSQHISDVLNGRADLMQRHGELIEAVFRGAMP"
     gene            5161..6153
                     /locus_tag="IG96_RS37875"
     CDS             5161..6153
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015700.1"
                     /locus_tag="IG96_RS37875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_196943382.1"
                     /sec_met_domain="AfsA (E-value: 2.4e-25, bitscore: 78.7,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRSLVHRAAVTEVFLTDGRRTDDGRVLIAAQWPCNHGLYRPDAA
                     GFSDPVLLVETVRQAAIYTSHRFYGVPLTHRFIFRSLDFHIDDADALRVAGAPLEVVLD
                     GALTPEVSRCEKRFGARFTARVEVGGQHCARVSVRLLAVGEQLYSMLRHRGSTPATTAA
                     HGNAGPRTAARMLPAPDVGQSQQGDVLISLDPATAADSYLVRLDRDHPGYFEHACDHVP
                     GMALVEAFRQTAHHLLRREEPATGTMRRMPISCEVSFDAFGELEEPLAVEIVNKVRTAS
                     PTGRHRISMAAVQRGRTLARAHAVYHAGPTAQPGEEDSWSSSSYASSAR"
     gene            6117..6437
                     /locus_tag="IG96_RS0135505"
     CDS             6117..6437
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 97; E-value: 2e-29)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035381.1"
                     /locus_tag="IG96_RS0135505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_051872433.1"
                     /transl_table=11
                     /translation="MEFQQLRVFREVARELSFTQAAKNLHCAQSTVTGQIKSLERSLGA
                     TLFHRRGRLPIELTDAGVLLRAHAERILVSVDSAAHEVRASTVPASPHTRAGTRPRPLA
                     RL"
     gene            6491..7177
                     /locus_tag="IG96_RS0135510"
     CDS             6491..7177
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01490.1"
                     /locus_tag="IG96_RS0135510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD-IB family hydrolase"
                     /protein_id="WP_030625021.1"
                     /transl_table=11
                     /translation="MEHSRSVIAFFDVDETLISVKSMLGFLAFHWEREGADPSRFAGAR
                     ARFAARQARGVPRDELNRDYYRLLRGVPHATLVRTGREWFSREAARTGFFHPPAVAALD
                     RHRRAGHLIALVSGAVRPCLEPLADAVGASLVLSAALEVEDGVLTGEVDTPVIGPEKAV
                     RARDAMRTYGSLPGDCYAYGDHSSDLPLLQAVGHPVVVGDDPVLAGQERRLGWRRLPGV
                     IAPRSG"
     gene            complement(7199..7789)
                     /locus_tag="IG96_RS0135515"
     CDS             complement(7199..7789)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 84.8; E-value: 1.7e-25)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /locus_tag="IG96_RS0135515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_051872434.1"
                     /transl_table=11
                     /translation="MVKQDRARRTHALVLDAAAAEFSALGFASTNLQVVAARTGLTKGA
                     LYGHFPSKSALAVEITRQFEESWRELLRCVDKETVLPLTALHALLLGLAQKIQTDVRFT
                     AGLRLVSEEARAKGEVPEVLTELRGAMLHLAQQAQKDGDIDAGIGAEPLSHLLLSLVLG
                     IHHTTSAGDSDSVYQRVVSAWELLLPLMRRPVR"
     gene            7964..9100
                     /locus_tag="IG96_RS0135520"
     CDS             7964..9100
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 329.4;
                     E-value: 4e-100)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981293.1"
                     /locus_tag="IG96_RS0135520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_030625026.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-10, bitscore:
                     31.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTAAPVAAGVAAQYAQQSEQGRELDHRVYTALNEAGFPRHFVPH
                     RWMGRAGTFAEALEAIAAVGEGCASAAWCAALQAAHGRLAAHLPETAQSELWQISPDVS
                     IAASVVPPSGELRRAPGGWFLSGTWGLASGVVHADWILLASLDRDAESQGAGEQGPGGA
                     TTRIMAVPRTDVRIHDTWRNSGLRGTGSHGLSVEQTFVPEHRSMPLEVLATGLRDPDAA
                     RCHRVPFPLVAALLFAAPALGAARGALRAWSELMRARPVTGGRPAHEDGSCQQVLARSS
                     AEIDAAGLLLAQAARRADSSPDPAGQVPLNRRDCAVAVDLLVTAVDRLFRSGGVRAQSE
                     GSALQRFWRDIHSVAAHATLRLEPAAAAYAQEVLATAR"
     gene            9381..12521
                     /locus_tag="IG96_RS37880"
     CDS             9381..12521
                     /NRPS_PKS="Domain: Condensation_LCL (6-303). E-value:
                     2e-35. Score: 114.1. Matches aSDomain:
                     nrpspksdomains_IG96_RS37880_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (463-859). E-value: 2.9e-92.
                     Score: 301.2. Matches aSDomain:
                     nrpspksdomains_IG96_RS37880_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (976-1038). E-value: 2.4e-15.
                     Score: 48.7. Matches aSDomain:
                     nrpspksdomains_IG96_RS37880_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     196.9; E-value: 1.2e-59)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012759.1,HMM:NF012873.1,HMM:TIGR01733.1"
                     /locus_tag="IG96_RS37880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_051872436.1"
                     /sec_met_domain="Condensation (E-value: 1.5e-35, bitscore:
                     112.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-102, bitscore:
                     332.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.3e-16, bitscore:
                     48.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKSQIFPVTEAQLGLLVIDRSVTARNLYNIILEVTLDPRFRPEE
                     VRAALAAVAEAQPALRLGLHHSPTPYAELSTPPTAEDLPLESHRVTHGEFSQRRAALLE
                     ELSAHAFALDEPPLFRASHLWQDDGGRSVLLFAVHHTVFDGFSTGPFARDLGAALRGGF
                     AADELRTEREAALRAELEAQLAAATAEDIESEVDELAAKLRSAPATELYPRPGRPGHTD
                     FIGERIELPLTAEESAAVDSLCRDLGVTSFTFYSSVYSAVLARHSGNSSATMGATLMSR
                     STLGSFDLCGFFVNTLPITVPVDWAAPFDEFTTKVVDDEVEDTKFRSHIPFNRVVERCA
                     PDRSGNRNPVFSALLAMQDSTVTEPGQPVLAVRQHGNGTAKFDLLLFATPTADGWLLEL
                     EYDRELLPPVVADGVATSLREAIRRAVSDPGRTVAELFEDVPPATHSAQAAPEPDHATV
                     YEWVIETAAAHPDRTAIVEDGAGTTYAELVRKAHELAHGLAHQGVGHGSVVGVATSGLT
                     ETVATVLAVLERRAAYLPLDPQLPAERLGAMVSQADCRLVVGAGEFGAASVRSATELAG
                     LAGAPAQPAPVRRSAADPVYTMFTSGSTGKPKGVLMGNGALVNLAHWQLGVLDMDGTTR
                     FMQYAPIGFDVSFQEIFPTLAAGGTLVSRDPVDRRDLPGLVRRVRETEVTHLYLPVAAL
                     RPFVLAAEEASADLPRLRHVCVAGEQLQADSAVRRFFRQRPHIRLFNMYGPTETHVVTA
                     HELSADALPWPSHVPIGRPIPGVSAQVVDVTGHLAPAGVPGELLLGGRCTAEGYVNDPE
                     RTAERFVPDPYGGHADARRYRTGDVVFRDEHGVLVYSGRDDHQVKIRGHRVELGELESA
                     ALNVPGVRSAVAAVRQDGAERQLVLFLVVHESAPADPQAVRGALAMTLPSYMLPAHLLV
                     VDSVPLSHNGKVDRTALLRDLPDLLGAESGTAPDTAEAGLDQPLVAEIRELWAELLGRH
                     VPVDGSLVDHGAHSLNVLTALSRIEQRYGVQVPVLDFFRTPTVRALAETVAAGRERA"
     aSDomain        9399..10289
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG96_RS37880_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.00E-35"
                     /label="IG96_RS37880_Condensation_LCL.1"
                     /locus_tag="IG96_RS37880"
                     /protein_end="303"
                     /protein_start="6"
                     /score="114.1"
                     /tool="antismash"
                     /translation="FPVTEAQLGLLVIDRSVTARNLYNIILEVTLDPRFRPEEVRAALA
                     AVAEAQPALRLGLHHSPTPYAELSTPPTAEDLPLESHRVTHGEFSQRRAALLEELSAHA
                     FALDEPPLFRASHLWQDDGGRSVLLFAVHHTVFDGFSTGPFARDLGAALRGGFAADELR
                     TEREAALRAELEAQLAAATAEDIESEVDELAAKLRSAPATELYPRPGRPGHTDFIGERI
                     ELPLTAEESAAVDSLCRDLGVTSFTFYSSVYSAVLARHSGNSSATMGATLMSRSTLGSF
                     DLCGFFVNTLPITVPV"
     aSModule        9399..12494
                     /complete
                     /domains="nrpspksdomains_IG96_RS37880_Condensation_LCL.1"
                     /domains="nrpspksdomains_IG96_RS37880_AMP-binding.1"
                     /domains="nrpspksdomains_IG96_RS37880_PP-binding.1"
                     /locus_tags="IG96_RS37880"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9462..9563
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0001"
                     /evalue="3.50E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="IG96_RS37880"
                     /protein_end="61"
                     /protein_start="27"
                     /score="12.9"
                     /tool="antismash"
                     /translation="LYNIILEVTLDPRFRPEEVRAALAAVAEAQPALR"
     CDS_motif       9792..9854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0002"
                     /evalue="3.40E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="IG96_RS37880"
                     /protein_end="158"
                     /protein_start="137"
                     /score="19.7"
                     /tool="antismash"
                     /translation="VHHTVFDGFSTGPFARDLGAA"
     CDS_motif       10203..10277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0003"
                     /evalue="8.60E-04"
                     /label="C5_LCL_267-296"
                     /locus_tag="IG96_RS37880"
                     /protein_end="299"
                     /protein_start="274"
                     /score="11.9"
                     /tool="antismash"
                     /translation="GATLMSRSTLGSFDLCGFFVNTLPI"
     CDS_motif       10365..10451
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0004"
                     /evalue="2.00E-07"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="IG96_RS37880"
                     /protein_end="357"
                     /protein_start="328"
                     /score="23.3"
                     /tool="antismash"
                     /translation="HIPFNRVVERCAPDRSGNRNPVFSALLAM"
     aSDomain        10770..11957
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG96_RS37880_AMP-binding.1"
                     /evalue="2.90E-92"
                     /label="IG96_RS37880_AMP-binding.1"
                     /locus_tag="IG96_RS37880"
                     /protein_end="859"
                     /protein_start="463"
                     /score="301.2"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="ETAAAHPDRTAIVEDGAGTTYAELVRKAHELAHGLAHQGVGHGSV
                     VGVATSGLTETVATVLAVLERRAAYLPLDPQLPAERLGAMVSQADCRLVVGAGEFGAAS
                     VRSATELAGLAGAPAQPAPVRRSAADPVYTMFTSGSTGKPKGVLMGNGALVNLAHWQLG
                     VLDMDGTTRFMQYAPIGFDVSFQEIFPTLAAGGTLVSRDPVDRRDLPGLVRRVRETEVT
                     HLYLPVAALRPFVLAAEEASADLPRLRHVCVAGEQLQADSAVRRFFRQRPHIRLFNMYG
                     PTETHVVTAHELSADALPWPSHVPIGRPIPGVSAQVVDVTGHLAPAGVPGELLLGGRCT
                     AEGYVNDPERTAERFVPDPYGGHADARRYRTGDVVFRDEHGVLVYSGRDDHQVKIR"
     CDS_motif       11166..11216
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0005"
                     /evalue="2.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="IG96_RS37880"
                     /protein_end="612"
                     /protein_start="595"
                     /score="23.2"
                     /tool="antismash"
                     /translation="YTMFTSGSTGKPKGVLM"
     CDS_motif       11628..11669
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0006"
                     /evalue="4.70E+00"
                     /label="NRPS-E2"
                     /locus_tag="IG96_RS37880"
                     /protein_end="763"
                     /protein_start="749"
                     /score="0.4"
                     /tool="antismash"
                     /translation="VVTAHELSADALPW"
     CDS_motif       11745..11834
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0007"
                     /evalue="1.70E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="IG96_RS37880"
                     /protein_end="818"
                     /protein_start="788"
                     /score="42.7"
                     /tool="antismash"
                     /translation="PAGVPGELLLGGRCTAEGYVNDPERTAERF"
     CDS_motif       11922..11987
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS37880_0008"
                     /evalue="2.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="IG96_RS37880"
                     /protein_end="869"
                     /protein_start="847"
                     /score="32.8"
                     /tool="antismash"
                     /translation="YSGRDDHQVKIRGHRVELGELE"
     aSDomain        12309..12494
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG96_RS37880_PP-binding.1"
                     /evalue="2.40E-15"
                     /label="IG96_RS37880_PP-binding.1"
                     /locus_tag="IG96_RS37880"
                     /protein_end="1038"
                     /protein_start="976"
                     /score="48.7"
                     /tool="antismash"
                     /translation="EIRELWAELLGRHVPVDGSLVDHGAHSLNVLTALSRIEQRYGVQV
                     PVLDFFRTPTVRALAET"
     gene            12518..13249
                     /locus_tag="IG96_RS0135530"
     CDS             12518..13249
                     /NRPS_PKS="Domain: Thioesterase (25-233). E-value: 4.2e-22.
                     Score: 71.5. Matches aSDomain:
                     nrpspksdomains_IG96_RS0135530_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.1"
                     /locus_tag="IG96_RS0135530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_030625041.1"
                     /sec_met_domain="PF00561 (E-value: 1.9e-07, bitscore: 21.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.4e-12, bitscore:
                     38.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTTSLVSSPLLIPLGHGEGTEQTVLLPAAGGGISPYFPLAGAL
                     TGRGPVHAIRSLGLMPGEDPDADVPTMVERYLDVMNALPRPPRYLVGWSLGGVLAWELA
                     SRLADRGDAPAVIMVDSYACLAERHGSDRDDALDHIGRSMGWATAADDPDQRERLRRTA
                     SAHLEAAYAHQASAGHTGPALLVSCTEGRGDDQLRQWAHRAPRLRVRELGCGHFEALDP
                     ARLPALRDHIDSFLADLAQDS"
     aSDomain        12593..13216
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG96_RS0135530_Thioesterase.1"
                     /evalue="4.20E-22"
                     /label="IG96_RS0135530_Thioesterase.1"
                     /locus_tag="IG96_RS0135530"
                     /protein_end="233"
                     /protein_start="25"
                     /score="71.5"
                     /tool="antismash"
                     /translation="VLLPAAGGGISPYFPLAGALTGRGPVHAIRSLGLMPGEDPDADVP
                     TMVERYLDVMNALPRPPRYLVGWSLGGVLAWELASRLADRGDAPAVIMVDSYACLAERH
                     GSDRDDALDHIGRSMGWATAADDPDQRERLRRTASAHLEAAYAHQASAGHTGPALLVSC
                     TEGRGDDQLRQWAHRAPRLRVRELGCGHFEALDPARLPALRDHID"
     CDS_motif       12776..12838
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG96_RS0135530_0001"
                     /evalue="3.60E-09"
                     /label="NRPS-te1"
                     /locus_tag="IG96_RS0135530"
                     /protein_end="107"
                     /protein_start="86"
                     /score="29.0"
                     /tool="antismash"
                     /translation="PRYLVGWSLGGVLAWELASRL"
     gene            13294..15264
                     /locus_tag="IG96_RS0135535"
     CDS             13294..15264
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 309.6; E-value:
                     8e-94)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960029.1"
                     /locus_tag="IG96_RS0135535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenazine-specific anthranilate synthase"
                     /protein_id="WP_051872438.1"
                     /transl_table=11
                     /translation="MPGSSTDQCSPVPLDGTPFALIHRPHATGRDRLELLRGDISAVPR
                     LADLPLAGTAESDATRAGRHELLALLPYRQISERGYVCNDDGAPLLVMEVHDQQELSVA
                     RFLADAPDTPPALTDAGFDISDEDYADVVRKVLAEEIGRGAGANFVIKRSFVGTLDGYG
                     PAAAVAFFARLLARETGAYWTFLVHTGERTFVGASPERHVSLESGTVTMNPISGTYRYP
                     ASGPTVQGALGLLGDRKEREELHMVVDEELKMMTRICDPGVRVKGPFLKEMDRLAHTEY
                     FIEGESALDVRHILRETMFAPTITGSPVENACQVLHQYEPKGRSYYSGALALIGRDVQG
                     QRAMDSAILIRTAEIDRAGRIEVGVGATLVRSSDPGSEVAETHAKVAGLLSALRQEPST
                     TPAGTAAGRRAEPGFLSRDPRVARALQRYNDGLAPFWLGPAPAGAHVVDALAGRRVLVV
                     DNEDTFTAMLGHQLRALGLSVTIRPWYDVPDPAVADADLVVVGPGPGDPRQTAQPKIAA
                     VRRLVERLLVSRVPFVAVCLGHQVLSSVLGIDLVRKDVPNQGLQQEIDFFGRRLRAGFY
                     NTFSGRAAADRADIDTASFTGPVEICRDARSGEVHGVRGAGFATAQFHPESLLTEDGPT
                     VLRDLVTTALSVMTASSGSHQ"
     gene            15276..16478
                     /locus_tag="IG96_RS0135540"
     CDS             15276..16478
                     /EC_number="2.5.1.54"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016909569.1"
                     /locus_tag="IG96_RS0135540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_107054275.1"
                     /transl_table=11
                     /translation="MTGRPDASLLRLPTGADALLRALPAEQQPQWGDHELLEKVCRELA
                     DSPPLVTSHEIVRLRALLADVAAGHAQVVQAGDCAEDPADHTADEVARKAGLIDCLAGV
                     LQARSGLPVLRVGRIAGQYAKPRSRPTESRDGTHLPAFRGPMVNAPQFDQQSREPDPLR
                     MLDCRRAAAAVLAELRDRNGAWPHSSPIWTSHEALVMDYELPQLRRDAYNRTFLTSTHW
                     PWIGERTRQLDGAHVQLLADVANPVACKVGPTMERDELLALAERLDPNRQPGRLTFISR
                     MGADSVGDRLPALAAALREAGHPVIWLCDPMHGNTFTGPGGYKTRSVPTVAREVRTFHA
                     AVTQAGGVAGGLHLEATAAPVVECVGDDGELDGLGAAYTTLCDPRLNLQQSIAIANTWP
                     C"
     gene            16500..17162
                     /locus_tag="IG96_RS0135545"
     CDS             16500..17162
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 289.8; E-value: 2.6e-88)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484455.1"
                     /locus_tag="IG96_RS0135545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismatase family protein"
                     /protein_id="WP_030625033.1"
                     /transl_table=11
                     /translation="MGIPAIQPYPMPSAADLPAGPADWKVDPERAVLLIHDMQKYFVDS
                     FPKDSEPVTSLTRNVRELREHCVKHAIPVTYTAQPGSMSDRDRGLLKDFWGPGMTVSPA
                     QREIVPGIEPEGGDQVFTKWRYSAFHRTGLLDFLRSHGRDQLIICGIYAHIGCLATAIE
                     SYTNDVETFFVSDAVADFTPEQHRMALEYTAGRCAVVLPTRTVVTQIETAPTTVETR"
     gene            17159..18478
                     /locus_tag="IG96_RS0135550"
     CDS             17159..18478
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) pgm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037360.1,HMM:NF037725.1"
                     /locus_tag="IG96_RS0135550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide ligase PGM1-related protein"
                     /protein_id="WP_030625035.1"
                     /sec_met_domain="pgm1 (E-value: 1.1e-183, bitscore: 600.7,
                     seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLFIANNRTAQMVGDLEELTPDHRRNAGVTAQRMIWYASEGDV
                     LVVPHVPSEEFLAYVTGLTGADRSKITVIAPPAGWLGTDVLTPDRWEDEEFLRELGEHV
                     RASGVDRVFPIYFDSSVIRLTRELGLDESTSGFPYIHQGGGQLLNSKATFRAVAAGGGC
                     PIPRGIVAFRRAEAEDFLWELLSEDRHAIVKKDFHVAGYGNAILSRDPGVTPIGAPEVT
                     VLNSRDDLAAHLDKQWGWYSEDGTRPVVVEDYAPDSSPVYAEFRITAHETTLFGHGEML
                     MGPIFNGLVIPAKATAHPEFPRFLDEAHRLCETVRTMGYRGPISVDGIVTPDDEILLNE
                     FNGRVGGSTHINYLAEQLVGDDFLRERLLIQRHHWPVPSFEEAVRRLEREGLAYDRDER
                     TGVVLTSDDSRLGGTVEYCLIAKDMSEAEKTEEVLAGLFG"
ORIGIN
        1 tcatgggtac tgcctgccct gagtcgcgca cgccgctcgg taccgtcgcg ggacagtgac
       61 gtcggtcagt gaccagtcat cgagttcagc ggggcggggg ccggcgccga cgtgtacgtg
      121 agagacaccc tcggccaggc cgtggcccgt tgccttcagg tatgcctcct tgcgggccca
      181 gcaccgggtg aatgcctcga gccgatcggc gctcggcagg cacgccagtt cctgccgctc
      241 ctcggtgtgc agggccgatg tcaccgcccg tgccgtgtcg ggccgtggta tctcctcgat
      301 gtccacgccg acggccgtgg ccgcgaccgc gacgagggtg aactcgccgc tgcgcgagag
      361 ggagaagtgc aggggcgcgc cgacgaccga gggccggccg tggccctcgc cacagcaggg
      421 gcaccgttct ctggcgtacc ggacacggtc cgccgcgatg ccgaggtagg caccgagcag
      481 tcgccgcagc atggcgtgtg cggcgaggta agcggcgcgg tccgcggcgt gtgcgaacgc
      541 ggccgcgcgc tcgcgttcct cggcgtcgag cagcgcctcg tcggcgccgg caacggcttc
      601 gccgggacgg tggcgcgcca gccacagtcg tggcgggcca ccgttccagc ggtccgggag
      661 cggtgtcgtg ccgtagcgaa gaggtacgac aggccgcacg tctcagctgc cctgtgccgg
      721 cccggccgtc gcctgctccg gctcctccaa cgcggacttc agggagcgga ggaaggccac
      781 tgcttcccgg ccgttgatga cccggtggtc gaaggcgagc cccaggtaca cgtacgacgt
      841 gcgggtcagt tctccgtcct cggtcaggtc gagagcctgc tgcgtgccgc cgagcgagag
      901 catgcaggtc tggccgggga agacgatcgg ctgggtgagg atcacgtcct cgtcgttgtt
      961 gagcgacagg gtgatcgcgg cgtcggtgag ttcgctgctc cggaagctgc cccggagtgc
     1021 ggagaagcgg aagtcgccca gctggtcggc gatctcgtcg acgctcttgc ggtcggcgtc
     1081 ccggacgaca ggtatgtaca gtccgctgcc caggtcgacc gtcactccga tgtgcgacgc
     1141 gtccgcgagc acgacgtgcc cgctgtcgtg gtaccggccg aagaaggcag ggaacgtccg
     1201 gcggagtccg gcaagttccg ctatcagcag ctcggtcagg ccgacggccg tgccactgcg
     1261 ttccgatgcg gccctggccg cggcttcggc ggcgtcggtt cggatccgta ccacggtgaa
     1321 ggacgcgggg accgtgcggt gcgactcact gaccacggcg ctgatcgcgc gctggtgctg
     1381 gctgagttcc agtcggctct cgtccggctc ggcgggggcg tcgcgccggg aggtgatctc
     1441 ctcgacgtcc gatcccttga tgatgcgctt gcccagagag gccagttccg cgtccgtgac
     1501 ggccagctcg gtggccagcc gacgcgcgga atcggtgagg atgaaccccg ccccgctgtc
     1561 gccgctgccg ctccggcccc cggcctcggc ggcttccgcg gcctcggcga ggaatgcctt
     1621 gcgctccgct tcacccggga agacccgggc caccacggtg ccgggggtga cctgcgtgcc
     1681 ggcgggcacc acatgcagca gcaccccgtc gtgctcgctg accaggtcct cggccgcctt
     1741 cgacgtctcc acggtgacga ggtcgtcgtc cttcgacacg gtggcgccgt ctgccacgag
     1801 ccactcgatg aggtcgtagg cggcgtcgtt gttgttcagc ttggggacgg tgatctcgat
     1861 catcggacca actctcgaag ggcggacccc acggaccggc tgctgaccac gacgtcccgc
     1921 tccagatgga gcgcagtggg gatgacggag tccgccgagt ggaccaggcg gacgggggcg
     1981 cgcagactct gccagcagtg cgagtagagc tggtgggcga cttcggcccc ccagctgccg
     2041 ccgggcgggg cgtcctccac gacgcagacg cggccggccc gggccaccgg atcggcgagg
     2101 acgctcacgt cgaaggggta cagcgcgctg ggtacgtaga cggcgcaggc gatctcgtgc
     2161 gacaggaaga gctcgcgcgc cgcctcgacg gcccggccgg cgagaccgcc cggtgcgatc
     2221 agcacgagct ccgggtcgcc gatcccgtcg atggagagcc gtgcggtggg gaaggggccc
     2281 tccccgacga actccagggt gaacaggtcg gcgaccagac cttcctggtg cctgcgctcg
     2341 gtgtagagga ccttgtcctc gaagaagatg ctgggcttgc ccagttcgat catgccgttc
     2401 aggacggcgg tgttgtcgtg gaacggggac agctcgaaaa ggtgcaggtc ggggacgccg
     2461 aggaagtgtt tctgcgggct ctggctgtgc gtcggtccgt aaccgcgccg ccctccgacc
     2521 gggcagcgga ccacgaggtg catcgggtgc tgcctgccgt acatcgcgac ggacttggcc
     2581 gagaagttca cgatctggtc gaaggccagc gtgatgaagt cgccgaacat catctcggcg
     2641 atcggcttgt tccccgtcag ggccagcccg ttggcgatgc ccagaatggc gttctcactg
     2701 atgggcgtgg tgagcacacg gtcaccgaag cggtccgaga gccccttggt gatgttgaac
     2761 gcgccaccgt acgggtcgag gacgtcctcg ccgatcagga aggtgtcgtc atgggccgcc
     2821 atgacgtcgt gcagggcgcg gttgaggttc tcgcccaccc gttcgttgcg cttcatgcca
     2881 cccctccgga gaccagcggc cgctccagga cgtccgcggc gacgaggtcg atcagttccc
     2941 gtaccttgtg gtcgtgccgg tcgaagcgct cggggtccgc cgcccggtag ccgccgtacc
     3001 agtcacgctg ccgcgcgcgc tcgacgacct cggcaggccg ggtgtcgtca cccttgctgt
     3061 gcggaccgag ccggacggtc tcgaactcga cgacgagcgg ctggtgctgg tggcgcaccc
     3121 gctcgatctc cggagccagc tcggcacgga tgcgatggat gtcatgggtc gtcacgcggt
     3181 ggtagccgac cccgaaagcc tccgcacggc cgcgtacggt gcctgccatg ttggccgcgc
     3241 tgggtgtggt ctgggagatg ccattgttct cgacgacgac cagaagcggg agttcccaca
     3301 gctgggcgat gttcagggcc tcgtagacgg aaccctcgcc ccacgtgccg tccccgatgt
     3361 acacggcggc cagcagcggg agttcgttgc gcttgaaatg cagtgccgcg ccggccgcaa
     3421 ccggcaggct ctcgccctgg ataccggtcg agaggtagct gccccggaag atgtgctgac
     3481 tgccgccgac gccaccgcag acggcgcctt cccggccggt gatctccgcc aggagaccgg
     3541 ccggatcggc gaaccgggcg aggtagtgcc cgtgcccgcg gtggttgctg aagacgaagt
     3601 cgtcctcggc cagcagcggg ttgagggaca ccgggacgta ctcctggccg aggcaggtgt
     3661 gcgtcgtacc gttcagcttc ccggcggcga acagatcgag gagcttccgt tcgaagtgcc
     3721 ggaccagcag cagcgattcc aggtcttcgt cgtcgagcgc ccgcagttcc gggggtgcct
     3781 gcgcggtgat cgtcacgccg ccgacacccc cttgctcctg aggacctcac gcaccgcgcc
     3841 cacggtcttc atggcgcgga cgtcctgccg ggagaaggac gtgccgtacc gctcctccag
     3901 ggcgatgatc agttgcatct gcttcaagct ggtccagcgg gcatcacgca cgggtcccag
     3961 gttgtcgtcc acctccccca ccgggatttg gatcacgtcc gagacaacct cttcaagctt
     4021 catgcgtcag acactccaga gaattgcggg tgctaccgag gttcaggtgc cgcacaaccc
     4081 ggggcggaca gtctggtgag cagacacggc tctccgggct gggagtgcca cagaatcaaa
     4141 ccttcgcgaa ggtttcaatt gagatcggga atcccgatcg aaggcggccg ggggtccctc
     4201 agcgtgtgac cctcagggca tggcgccgcg gaagacggct tcgatcagtt cgccatgacg
     4261 ctgcatcagg tcggcgcggc cgttcagcac gtcggatatg tgctgactgc cgaagaaagc
     4321 ggcgaccacc acacgggcca gcgctgccgg gtcgacgtcc gcacgcagct ggccggcatc
     4381 ccgagcctcg gtgatcagtg acgtcagcag ttcctgccat cccacgtagg gcaccgggag
     4441 atccgccttg atcagcgaac gctcgatctg cagacgggcc cccgcctgca ccatcacgtc
     4501 gtcccggaac gcctccgccg caccctccag aacggcgagc agcgtctcga gcggcggcag
     4561 cccacgcgag cgcacctcac tgacgagcgg ttcccagcga gcgtagtgct ccatgatcac
     4621 cgcgacggcg agggcttcct tgttcgcgta gtggaagtag accgcaccct tggtcatcga
     4681 cgcccgctcg gccaccgcct gcagcgtgac cgcggggtat ccgtgctcct tgaacgcctc
     4741 cgcggcggtc cgcagcacca gccgcttggt ctgccgtgcg cgttcctgct tcggctcccg
     4801 gcgggagtgc gccaccggcc cgtgagtagc tgccttgctg tccatgcctc aggtgcgtcc
     4861 caactgatgt cgactgcctc tgctcccgcc ggcacccctg cgaggggatg atccggtcga
     4921 gttgcctgac ccccttgcca gcgatccagc gacccatgca atataccttc ccataggtat
     4981 attttttcgc tccacagggc gggaaattct ttccgttcag cggaatatct aaggggggtc
     5041 gatttgatgt cacccagccg gttgactatt cgtccaagag tccatggcct caggagcgcg
     5101 ccgaggggag cggcctcgac cacggggcaa gggcgcacga cactcacctt cgaccggacg
     5161 gtgccacgtt ccttggtcca ccgcgcggcg gtcaccgaag tgttcctgac cgacggccgt
     5221 cgcaccgacg acggccgcgt gctgatcgcc gcccaatggc cgtgcaacca cgggctgtac
     5281 cgcccggacg ccgccggatt cagcgatccg gtactcctgg tggaaaccgt ccgccaggcc
     5341 gcgatctaca cgagtcaccg cttctacggg gtgccgctca cgcaccggtt catcttccgc
     5401 agcctcgact tccacatcga cgacgccgac gcgttgcgag tggcgggagc tccgctggag
     5461 gtggtgctcg acggggcgct gacccccgag gtcagccggt gcgagaagcg gttcggcgca
     5521 cgtttcacgg cccgtgtcga ggtcggcgga cagcactgcg cccgggtgtc ggtgcgcctg
     5581 ctcgcagtgg gtgagcagct gtactccatg ctgcgccacc gcggcagcac gcccgccacg
     5641 accgccgcgc acggcaacgc cggcccccgt accgcagcca ggatgctgcc cgctccggat
     5701 gtcggccagt cgcagcaggg cgacgtcctg atctccctcg acccggcgac ggcggcggat
     5761 tcgtacctgg tacgcctcga ccgcgaccac cccggctact tcgagcacgc ctgcgatcac
     5821 gtccccggca tggcactcgt cgaagccttc cgccagacag cacaccacct gctgcggcgg
     5881 gaggagcctg ctacgggcac catgcgccgc atgccgatct cctgcgaggt ctccttcgac
     5941 gctttcggcg agctggagga gcccctcgcc gtcgagatcg tcaacaaggt gcggaccgcc
     6001 tctcccaccg gccggcaccg gatctcgatg gcggccgtgc agcgcgggcg gaccctcgcc
     6061 cgggcccatg ccgtctacca cgccggcccc accgcgcagc ctggagagga ggactcgtgg
     6121 agttccagca gctacgcgtc ttccgcgagg tagcacggga gttgagcttc acccaggcgg
     6181 cgaagaacct gcactgcgcg cagtccaccg tcacgggcca gatcaagagc ctcgaacgct
     6241 cgctgggggc cacgctcttc caccggcggg gccgtctgcc catcgaactc accgatgccg
     6301 gagtactgtt gcgggcccac gcggagcgca tcctcgtctc ggtggactcc gccgcgcacg
     6361 aggtccgcgc gagcacggtc cccgcttccc cgcacacccg ggccggcact cgcccccgcc
     6421 cgctggcacg tctctgaccg ccgggccgac gggtcgtacc gatcggccgg attctcctga
     6481 tcggaacagc gtggagcact cccgttcggt catcgccttc ttcgacgtgg acgagaccct
     6541 gatctccgtc aagagcatgc tgggctttct cgccttccac tgggagcggg agggggccga
     6601 cccctcccgc ttcgccggcg cgcgtgcccg gttcgccgcc aggcaggccc ggggtgtgcc
     6661 ccgtgacgag ctcaaccgcg actactaccg gcttctgcgt ggtgtcccgc acgccactct
     6721 cgtccggacc ggccgtgagt ggttcagcag ggaggccgcc cgcacggggt tcttccatcc
     6781 gcccgccgtc gcggcgctgg accgccatcg ccgggccggg catctgatcg ccctggtgtc
     6841 gggcgcggta cggccgtgcc tggaaccact ggccgacgcc gtgggcgcct cactggtgct
     6901 gtccgccgct ctcgaagtcg aggacggcgt gctcacgggc gaggtggaca ccccggtcat
     6961 cggcccggag aaggccgtgc gcgcccggga cgccatgcgc acgtacgggt cccttccggg
     7021 cgactgctac gcatacggtg atcactccag cgatctgccg ctgctgcagg cggtgggcca
     7081 cccggtcgtc gtcggcgacg acccggtgct cgccggtcag gaacggcgcc tgggttggcg
     7141 caggttgccg ggcgtcatcg cccctcgctc gggctgaggg atgagcgcag cgataccgtc
     7201 accgcacggg gcgccgcatc agcggcagca gcaactccca ggcactgacg acccgttggt
     7261 acacactgtc gctgtcaccg gccgacgtgg tgtggtgaat gccgagcacc agggacagca
     7321 gaagatggct gagcggctcg gcgccgatcc cggcgtcgat gtctccgtcc ttctgcgcct
     7381 gctgggcgag gtggagcatc gcgccccgca actccgtcag tacctccggc acttcaccct
     7441 tcgcccgggc ttcctcggag accagccgga gcccagcggt gaagcgcacg tccgtctgga
     7501 tcttctgggc cagccccagc aacagggcgt gcagcgcggt gagcggcagg accgtctcct
     7561 tgtcgacgca ccgcagcaac tcgcgccagc tctcctcgaa ctgccgggtg atctctaccg
     7621 ccagtgcgct cttcgaaggg aagtgtccgt acagcgcgcc cttggtgagt ccggtgcgtg
     7681 ccgccaccac ctggagattg gtgctggcga acccgagggc ggaaaactcc gcggcagccg
     7741 cgtccaagac cagcgcgtgc gtacgtcgcg ccctgtcctg tttgaccata tccgtggttc
     7801 cttacgcttc cgtcacgccc acgaagaaac ttccaaggcg gatcttttct cattgggatg
     7861 cccaacacaa gacatccacc gccgccgatc ccccacctaa gcggacaaaa ccatcaagga
     7921 gacgttttcc gtgtccactt ctccctgccc caccacgacc actctgcgca ccgcggcccc
     7981 tgtcgccgcc ggtgtggccg cgcagtacgc acagcaatcc gaacagggcc gtgaactgga
     8041 ccaccgggtg tacacggcgc tcaacgaggc gggtttcccg cgtcacttcg tgccgcaccg
     8101 ctggatgggc cgcgcgggca cgttcgccga agcactcgaa gccatagcgg ctgtcgggga
     8161 gggctgcgct tccgcagcct ggtgcgccgc gctgcaggcg gcgcatggcc gactcgcggc
     8221 acatctgccc gagacagccc agagcgaact gtggcagatc tcgcccgacg tgtccatcgc
     8281 ggcatcggtc gtcccgccct ccggcgagct ccgacgagcc cccggcggct ggttcctctc
     8341 cggtacctgg ggcctggcca gcggagtggt tcatgcggac tggatactgc tggcctccct
     8401 ggaccgggac gccgagagcc agggcgccgg ggaacagggc cccggtggcg ccacgacgcg
     8461 catcatggcc gtgccacgca cggacgtccg catccacgac acctggcgca actccggcct
     8521 gcggggcacg ggaagccacg ggctctcggt ggagcagacc ttcgtccccg agcaccgcag
     8581 catgccgctg gaggtacttg ccaccggact acgggacccg gacgcggcac gctgccaccg
     8641 cgtccccttt cccctggtgg cggcgctgct cttcgccgca ccggccctgg gcgctgcgcg
     8701 cggtgcactg cgcgcgtggt cggagctcat gcgcgcgcgc ccggtcaccg gcggccggcc
     8761 cgcccacgag gacggcagtt gccagcaggt gctcgcccgc tcctcggccg agatcgacgc
     8821 cgcaggcctg ctgctcgccc aggcggcgcg tcgggccgac agctcgcccg accccgccgg
     8881 acaggtgccg ttgaaccgac gggactgcgc ggtggcggtg gacctgctgg tcacggcggt
     8941 cgaccggctg ttccgcagcg gaggcgtccg agcgcagagc gagggcagcg cgctgcagcg
     9001 gttctggcgg gacatccatt cggtggccgc ccatgccacc ctgcggctcg agcccgccgc
     9061 ggcggcctac gcccaggagg tactggcaac ggcgcggtga gcgccgccac caggcgcctc
     9121 tggtgacaca gcacccgccc cccagcccct gccggcctgc cggcgtccgg ccaggggctt
     9181 ttccatcggg gtctccgatg acatttgaat acctccgcga aggaatgatt tcgtgagcgt
     9241 gggtcgtcac ccacgagcct gcgctccgga tggtgcgagc gcagtggggc ccgaacgccg
     9301 ccgatgccgt gccgatgccg acaggccgcc ccgcttgccg ccgcgaccag cgccacccgc
     9361 atacccgtga ggtcattcct gtgcagaaaa gccagatatt tccggtcacc gaagctcagc
     9421 tagggctgct cgtcatcgac cgttcggtca ctgcgcgcaa cctgtacaac atcatcctcg
     9481 aagtcacgct cgacccgcgc ttccgtccgg aggaggtacg cgccgcactg gcggcggtgg
     9541 cggaggcgca gccggcactc aggctcgggc tccaccactc acccaccccc tacgcggagt
     9601 tgtccacccc accgaccgcg gaggacctcc ccctcgagtc ccaccgggtc acccacggag
     9661 agttctccca gcggcgtgcg gcgctcctgg aggaactctc cgcacacgcc ttcgccctgg
     9721 acgaaccgcc gctgttccgc gcgagccacc tctggcagga cgacggcggc cggtcggtgc
     9781 tgctgttcgc cgttcaccac acggtcttcg acggcttctc caccggcccc ttcgcacggg
     9841 acctcggcgc ggcactccgg ggcgggttcg cggccgacga actccgcacg gagcgggagg
     9901 cggcgctgcg cgccgagctc gaggcccaac tcgccgctgc caccgccgag gacatcgagt
     9961 cggaggtcga cgagctggcc gccaagctgc gcagcgcccc tgccaccgag ctctacccca
    10021 ggccgggccg gccggggcac accgacttca tcggcgagcg catcgagctg ccgctcaccg
    10081 ccgaggagtc cgccgcggtg gactcgctgt gccgggacct gggcgtcacc tcgttcacct
    10141 tctactcctc cgtctactcg gcggtgctcg cccggcactc gggcaattcc tcggcgacga
    10201 tgggcgcgac actgatgtcg cggagcacac tcggctcctt cgacctgtgc ggcttcttcg
    10261 tcaacacact gccgatcacc gtcccggtcg actgggccgc gcccttcgac gagttcacga
    10321 ccaaagtcgt ggacgacgag gtcgaggaca ccaagttccg ttcccacatc cccttcaacc
    10381 gcgtggtgga acggtgcgcg cccgaccgct ccggcaatcg caacccggtg ttctccgcgc
    10441 tgctcgcgat gcaggacagt acggtgaccg agccggggca gccggtactc gccgtacgtc
    10501 agcacgggaa cggcacggcc aagttcgacc tcctgctctt cgccaccccc acagctgacg
    10561 gatggctcct ggagctggag tacgaccgcg aactgctgcc gccggtggtg gcggacgggg
    10621 tggccacgtc cctgcgggaa gcgatccgcc gcgcggtgag cgaccccggg cgcaccgtcg
    10681 ccgaactgtt cgaggacgtc ccgcccgcca cgcacagcgc gcaggccgca ccggaacccg
    10741 accacgccac cgtgtacgaa tgggtcatcg agaccgcggc cgcgcatccg gaccgcaccg
    10801 cgatcgtcga ggacggcgcc ggcaccacct acgcggagct ggtccggaag gcccacgagc
    10861 tcgcacacgg gctggcccac cagggagtcg gacacggaag cgtggtcggg gtcgccacct
    10921 ccggcctcac cgagacggtg gcgaccgtac tggcggtcct ggaacgcagg gccgcctatc
    10981 tgcccctcga tccgcagctg cccgcggaac ggctcggcgc gatggtctcc caggcggact
    11041 gccggcttgt cgtgggcgca ggcgagttcg gcgccgcttc ggtccggtcc gccaccgagc
    11101 tggccggcct ggccggggcg ccggcgcagc cggcaccggt acggcgttcg gctgccgacc
    11161 ccgtctacac gatgttcacc tccggctcca cggggaagcc caagggcgtc ctcatgggca
    11221 acggcgccct ggtgaatctc gcccactggc agctcggcgt gctggacatg gacgggacca
    11281 cccgcttcat gcagtacgcg cccatcggct tcgacgtctc cttccaggag atcttcccga
    11341 ccctggcggc aggcgggacc ctcgtctccc gtgaccccgt ggaccggcgg gacctccccg
    11401 gcctggtccg gcgcgtgcgg gagaccgagg tcacccacct ctacctgccg gtggcggcac
    11461 tgcgcccctt cgtcctcgcg gccgaggagg cctcggcgga tctcccccgg ctccgccatg
    11521 tatgtgtggc aggcgagcag ttgcaggcgg acagcgcggt gcgcaggttc ttccggcagc
    11581 gcccgcacat ccggctgttc aacatgtacg ggcccacgga gacccatgtc gtcacggctc
    11641 acgagctgtc cgccgacgcg ctgccctggc cctcccacgt tcccatcggc cgcccgatcc
    11701 ccggcgtcag tgcgcaggtc gtggacgtca ccgggcatct cgctcccgcc ggagtgccgg
    11761 gcgaactgct gctcggcggc aggtgcaccg ccgagggcta cgtcaacgac ccggagcgca
    11821 ccgcggagcg tttcgttccc gacccctacg gcggacatgc ggacgcccgc cgctaccgga
    11881 cgggcgacgt ggtcttccgc gacgagcacg gggtgctcgt gtactccgga cgggacgacc
    11941 accaggtgaa gatccgtggt caccgcgtgg aactcggtga gctggagtcg gcggcgctga
    12001 acgtacccgg cgtccggtcg gcggtcgcgg cggtccgtca ggacggcgcg gagcggcagt
    12061 tggtgctgtt cctggtcgtt cacgagtcgg caccggccga cccgcaggcc gtacgcggcg
    12121 cgctggccat gacccttccc tcgtacatgc tgccggctca tctcctggtg gtggactccg
    12181 ttccgctcag ccacaacgga aaggtcgacc gaaccgctct gctgcgggac ctgcccgacc
    12241 tgttgggcgc ggagtcgggc accgcaccgg acaccgcgga ggccggcctc gaccagcccc
    12301 tggtggcgga gatccgggag ctgtgggccg aactcctcgg caggcacgtg cccgtggacg
    12361 gctccttggt ggaccacggt gcccattcgc tgaacgtact caccgccctc agccggatcg
    12421 agcagcgcta cggcgtgcag gtaccggtcc tcgacttctt ccgcaccccc accgtgcgcg
    12481 ctctggccga gacggtcgcg gcgggacggg agcgggcatg agcaccacca catccctggt
    12541 ctcctctccc ctgctgatcc cgctgggaca cggcgagggc acggaacaga ccgtgctcct
    12601 gcccgccgcg ggtggcggta tcagcccgta cttcccgctg gccggcgccc tgaccggcag
    12661 ggggccggtg cacgcgatcc ggtcgctggg gctcatgccc ggcgaggacc ccgacgccga
    12721 cgtgcccacg atggtcgagc gctacctcga cgtcatgaac gccctccccc ggccaccccg
    12781 ttacctcgtc ggctggtccc tcggcggggt gctggcctgg gagctggcct cccggctcgc
    12841 ggaccggggc gacgctcccg cagtgatcat ggtggacagc tatgcgtgtc tcgccgagcg
    12901 ccacggctcc gaccgcgacg acgcgctgga ccacatcggc cggtccatgg gctgggccac
    12961 cgccgcggac gacccggacc agcgggaacg gctgcggcgc accgcgtcgg cgcacctcga
    13021 agcggcatac gcgcaccagg cgtcggcggg ccacaccggc cccgccctgc tggtctcctg
    13081 cacagaagga cgcggcgacg accagctccg gcagtgggca caccgcgcac cgcgcctccg
    13141 ggtccgggaa ctgggctgcg gccacttcga ggctctcgac cccgcccggc tgcccgcact
    13201 ccgcgaccac atcgacagct tcctggcgga cctcgcccag gactcatgag ggctgacaag
    13261 gaaatcgaca tgccgcacac acagacgggc tccatgccgg ggtcctcgac cgaccagtgc
    13321 tcccccgtgc ccctcgacgg cacgcctttc gccctgatcc accgtccgca cgcgaccgga
    13381 cgggaccgcc tcgaactcct ccgcggcgac atctccgcgg taccgcgcct ggccgacctc
    13441 ccgctcgccg gcaccgcgga gagcgatgcg acacgggccg gccggcacga actgctcgcg
    13501 ctgctgccct accggcagat ctccgagcgc ggctacgtct gcaacgacga cggagcgccg
    13561 ctcctggtga tggaggtcca cgaccagcag gagctgtccg tcgcgcggtt cctcgcggac
    13621 gcgcccgaca ccccgccggc cctcaccgat gccggcttcg acatctccga cgaggactac
    13681 gccgacgtcg tccggaaggt gctcgccgag gagatcgggc gcggagccgg cgccaacttc
    13741 gtcatcaagc gctccttcgt cggcaccctc gacggctacg gcccggccgc tgccgtggcc
    13801 ttcttcgccc gcctgctcgc ccgggaaacg ggcgcgtact ggaccttcct cgtgcacacc
    13861 ggtgagcgga cgttcgtggg cgcgtcgccc gagcgccacg tcagcctcga gtccggcacc
    13921 gtcaccatga atccgatcag cggtacgtac cgctaccccg cctccgggcc cacggtccag
    13981 ggagcgctcg gcctcctcgg cgaccgtaag gagcgcgaag agctccacat ggtggtggac
    14041 gaggaactga agatgatgac ccggatctgt gacccgggcg tacgggtgaa gggcccgttc
    14101 ctgaaggaga tggaccggct cgcccacacc gagtacttca tcgagggcga gagcgcgctg
    14161 gacgtacggc acatcctgcg ggaaacgatg ttcgcgccca ccatcaccgg cagtccggtg
    14221 gagaacgcct gccaggtcct ccaccagtac gagccgaagg gacgctccta ctacagcggg
    14281 gccctcgccc tcataggccg ggacgtgcag gggcagcgcg ccatggactc cgccattctg
    14341 atccgcaccg cggagatcga ccgggcaggc cggatcgagg tcggggtcgg ggccacgctg
    14401 gtgcgctcct ccgaccccgg cagtgaggtc gccgagacgc acgccaaggt cgccggcctg
    14461 ctctccgccc ttcggcagga gccgtcgacg acgcctgccg gcacggcggc cgggcgccgg
    14521 gccgagcccg gcttcctcag ccgggacccg cgggtggcgc gtgccctcca gcggtacaac
    14581 gacggactcg cccccttctg gctcggcccc gcccccgcgg gggcccacgt cgtcgacgcc
    14641 ctggcgggcc ggcgggtgct ggtggtggac aacgaggaca ccttcaccgc catgctcggt
    14701 caccagctgc gcgccctggg tctctcggtg accatccggc cctggtacga cgtaccggac
    14761 ccggcggtcg ccgacgccga cctggtcgtc gtggggcccg gccccggcga cccgaggcag
    14821 accgcccagc cgaagatcgc cgcggtgcgc cgtctggtcg aacggctgct ggtgtcccga
    14881 gtgccgttcg tggcggtgtg cctgggacac caggtgctct cctccgtcct cggcatcgac
    14941 ctggtgcgca aggacgtccc gaaccagggc cttcagcagg agatcgactt cttcggccgc
    15001 cggctgcgtg ccgggttcta caacaccttc agcggccggg cggccgccga ccgggcggac
    15061 atcgacacgg cgtcgttcac gggaccggtg gagatctgcc gggacgcacg cagcggcgag
    15121 gtgcacggcg tgcgcggggc cgggttcgcg accgcgcagt tccatcccga atcgctgctg
    15181 accgaggacg ggccgaccgt gctgcgcgac ctcgtgacca ccgccctgtc cgtgatgacc
    15241 gcttcatcgg ggagccacca gtgatcaata cggccatgac ggggcgcccg gacgcctcct
    15301 tgctgcggct gccgaccgga gccgatgccc tgctcagggc gcttccggcg gagcagcagc
    15361 cgcagtgggg cgaccatgag ctcctggaga aggtctgccg ggaactggcg gacagtccgc
    15421 cgctcgtgac gtcgcacgag atagtccggc tgcgcgccct gctcgcggac gtcgcggcgg
    15481 gccacgccca agtggtgcag gccggcgact gcgccgagga tccggcggac cacacggcgg
    15541 acgaggtcgc gcgcaaggcc gggctgatcg actgcctggc gggcgtgctg caggcccgct
    15601 cgggactgcc cgtactgcgc gtgggccgca tcgccggcca gtacgccaag ccgcgttcgc
    15661 ggcccaccga gagcagggac gggactcatc tccccgcgtt ccgcgggccc atggtcaacg
    15721 caccgcagtt cgaccagcag tcgcgggaac ccgacccgct gcgcatgctc gactgccgcc
    15781 gggcggctgc cgcggtcctc gcagagctgc gcgaccgcaa cggcgcctgg ccgcacagct
    15841 ccccgatatg gaccagccac gaggcgctgg tcatggatta cgagctgccc cagctgcgcc
    15901 gggacgcgta caaccgcacg ttcctgacgt ccacccactg gccgtggatc ggtgagcgga
    15961 cgcgtcagct ggacggtgcg cacgtgcagt tgctggccga cgtggcgaac cccgtggcct
    16021 gcaaggtcgg ccccaccatg gaacgcgacg agctgctcgc gctggccgaa cgcctcgacc
    16081 ccaaccggca gcccggtcgg ctgacgttca tctcccggat gggcgccgac agcgtgggcg
    16141 accggctccc ggccctggca gcggccctcc gcgaagcggg gcatccggtc atctggctgt
    16201 gcgaccccat gcacggcaac acgttcaccg gcccgggcgg atacaagacc cgttccgtcc
    16261 cgacggtcgc gcgcgaagtc cggacgttcc acgccgcggt cacgcaggcc ggcggcgtgg
    16321 cgggcgggct gcatctggaa gccaccgcgg ccccggtcgt cgagtgcgtc ggcgacgacg
    16381 gcgagctgga cggcctcggt gccgcctaca ccacgctgtg cgacccccgg ctcaaccttc
    16441 agcagtccat cgccatcgcc aatacctggc cctgctaacg gagaggtgtc cttccgtcca
    16501 tgggaatccc cgccatccag ccctacccca tgccctcggc agcggacctt ccggccggcc
    16561 ctgccgactg gaaagtcgac cccgagcggg ccgtacttct catccacgac atgcagaagt
    16621 acttcgtcga ttccttcccc aaggattccg agccggtgac ctccctcacc cggaacgtcc
    16681 gtgaactgcg ggaacactgc gtcaagcacg cgatcccggt gacctacacc gcgcagcccg
    16741 gcagcatgag cgaccgggac cgcggcctgc tgaaggactt ctggggcccg ggaatgacgg
    16801 tgagccccgc ccagcgggag atcgtcccgg gcatcgagcc cgagggcggc gaccaggtgt
    16861 tcaccaaatg gcggtacagc gccttccacc gcaccggtct gctcgacttc ctgcgctcgc
    16921 acggccgcga ccagctgatc atctgcggca tctacgccca tatcggctgc ctggccaccg
    16981 ccatcgagtc ctacacgaac gacgtggaga cgttcttcgt gtccgacgcg gtcgccgact
    17041 tcacccccga acaacaccgc atggccctgg agtacacggc cggacgctgc gcggtggtcc
    17101 tgcccacccg gacggtcgtg acccagatcg agacggcccc gacgacagtg gagacccgat
    17161 gagcaccctg ttcattgcca acaaccggac cgcgcagatg gtcggcgacc tcgaggagct
    17221 gactcccgac caccgcagga acgcgggcgt gaccgcccag cgcatgatct ggtacgcgtc
    17281 cgagggcgat gtcctcgtgg tgccgcacgt ccccagcgag gagttcctgg cctacgtcac
    17341 cggcctcacc ggcgcggacc gctcgaagat cacggtcatc gcgccgccgg ccgggtggct
    17401 cggcaccgac gtgctcaccc cggaccgctg ggaggacgag gagttcctgc gcgagctcgg
    17461 ggagcacgtg cgggcatcgg gggtcgaccg ggtgttcccg atctacttcg acagttcggt
    17521 catccggctc acccgcgagc tggggctcga cgagtcgacc tccggattcc cctacatcca
    17581 ccagggcggc gggcagctcc tcaacagcaa ggccaccttc cgggcggtgg ccgccggcgg
    17641 cgggtgcccg attccgcgcg gcatcgtcgc gttccggcgc gccgaggcag aggacttcct
    17701 gtgggagctg ctgtcggagg accggcacgc gatcgtgaag aaggacttcc acgtcgccgg
    17761 ctacggcaac gccatcctca gccgcgaccc gggcgtcacc cccatcggcg ccccggaggt
    17821 caccgtgctg aacagccggg acgacctcgc ggcgcacctg gacaagcagt gggggtggta
    17881 ctcggaggac ggcacacggc ccgtggtggt cgaggactac gcgccggaca gcagcccggt
    17941 ctatgccgag ttccgtatca cggcccacga gactacgctg ttcggccacg gggaaatgct
    18001 gatgggcccg atcttcaacg gtctcgtcat tccggcgaag gcgaccgccc atccggagtt
    18061 cccccgcttc ctggacgagg cgcaccgcct ctgcgagacc gtacgcacca tgggctaccg
    18121 cggtcccatc agcgtcgacg gcatcgtgac gcccgacgac gagatcctgc tcaacgagtt
    18181 caacggccgg gtcggcggct ccacccacat caactacctg gccgagcagc tggtcggcga
    18241 cgacttcctg cgcgagcgcc tcctcatcca gcgtcaccac tggcccgtcc cgtccttcga
    18301 ggaagccgtg cgccggctgg agcgcgaagg gctggcgtac gaccgggacg agcggaccgg
    18361 agtcgtcctc acctccgacg acagccggct cggcggcacc gtcgagtact gcctgatcgc
    18421 caaggacatg tccgaggcgg agaagaccga ggaagtactg gccgggctgt tcggctga
//
