Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001776.1:
Cluster 1Terpene168344

BGC0001776, shearinine D biosynthetic gene cluster from Penicillium janthinellum. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: shearinine D
SMILES string: Copy to clipboard

Class-specific details

Biosynthetic class(es):
Terpene

Gene cluster description

shearinine D (BGC0001776). Gene Cluster 1. Biosynthetic class = Terpene. GenBank KF280651. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Nicholson MJ et al. (2015) Molecular Cloning and Functional Analysis of Gene Clusters for the Biosynthesis of Indole-Diterpenes in Penicillium crustosum and P. janthinellum. Toxins (Basel) 7(8):2701-22. doi: 10.3390/toxins7082701.
2. Liu C et al. (2016) Biosynthesis of Shearinine: Diversification of a Tandem Prenyl Moiety of Fungal Indole Diterpenes. Org Lett 18(19):5026-5029. doi: 10.1021/acs.orglett.6b02482. Epub