LOCUS       BGC0001778             16475 bp    DNA     linear   BCT 15-MAY-2015
DEFINITION  Streptomyces showdoensis strain ATCC 15227 ATCC_15227_cotig_45,
            whole genome shotgun sequence.
ACCESSION   BGC0001778
VERSION     BGC0001778
KEYWORDS    .
SOURCE      Streptomyces showdoensis
  ORGANISM  Streptomyces showdoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:16:28
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1335)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 400.9;
                     E-value: 7.3e-122)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_017241941.1"
                     /locus_tag="VO63_13540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diaminopimelate decarboxylase"
                     /protein_id="KKZ73322.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.8e-63, bitscore:
                     204.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 5.7e-21,
                     bitscore: 64.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTPLPPVAVPAGDLSVWPARTVERPDGRLYVGGVALDELAESH
                     GTPVYVLDEAEVRDRCRAYRDAFPGADVHYAAKAFLCRALAHWVEEEGLGLDVCSAGEL
                     ELAVTTGFPPERILLHGNAKSPEDLRTALRLGVGRIVIDSPAEIARIAAAVGPGERQRV
                     MLRVTPGISAGGHAKVRTGSDDQKFGLSLRDGHAQHAIARLLGQPRLRLTGLHCHLGSQ
                     ITDVKPYLVAVRRLVGLMARTRDAHGVVLSELDLGGGHGIAYRPGDRALDPAALARRVR
                     AELAESCAGAGLPVPRLIVEPGRAISGPAGVVVYRVLAVKATPERFFVAVDGGMSDNPR
                     PALYGVRYAPRLIGRRSAAGPRRATVVGRHCEAGDVLAEDVPLPSDVRPGDLLAVPVAG
                     AYHLSMASSYNLVGRPPVVAVAAGAGRLLVRRETQADLRARDVGL"
     subregion       1..16475
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001778"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..16475
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1335)
                     /locus_tag="VO63_13540"
     gene            complement(1515..1835)
                     /locus_tag="VO63_13545"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            2073..3191
                     /locus_tag="VO63_13550"
     CDS             2073..3191
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_019063739.1"
                     /locus_tag="VO63_13550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KKZ73234.1"
                     /transl_table=11
                     /translation="MTYVVTVETRIPGGAPELDELSRVGAGTLLERGFDSVAGVEGPDG
                     VEVDVLDVVVGVHPGGAILKVFVEAPSLEVAEDAVGSVTQEVLERSEVLAEWVVESSEV
                     KLHTDLARESLEAADGPDAPPSDPQVRRAQHALKAAETFETAEETHDPEAEIRAMAARL
                     RSFTPATFGVADPVDEFGVGPGGAELAAGALVYGAEVLIDELYDDVQALADEDTNVAGC
                     EGHLWHLDQLPARYASRYDELFARRFLVTAVALTTRFTDGGFERLGCLAEELVLKFLLE
                     QAHVTLDLYGLLDDEVTAALECFATEVYEDGDFEWLFDGGAEGAERAEEADGADGPDGP
                     APGFGTWFTPFGEDRYVHPYAADEHVQEPEDA"
     gene            3310..3969
                     /locus_tag="VO63_13555"
     CDS             3310..3969
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_017242093.1"
                     /locus_tag="VO63_13555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="KKZ73235.1"
                     /transl_table=11
                     /translation="MFVKVCGLATTADIDVAAEAGADAIGLVISRTSVRGLDWDRAVAL
                     AAHVPSHVRSVLVVNDTAAADAARAANELGVDALQLHGTYTRADFDEAARTFPRLWRAT
                     SLNEKPDTRVGAYGEEVLLLDSPRAGSGARWDLSLLDAARPEGAWLLAGGLGPDNVAEA
                     IRQADPWGVDVSSGVESAPGVKDHARIHAFVTAARTAAGRDHGQPQDRGREQDRGR"
     gene            complement(4375..5010)
                     /locus_tag="VO63_13560"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            complement(5007..6395)
                     /locus_tag="VO63_13565"
     CDS             complement(5007..6395)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 321.6; E-value:
                     1e-97)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_010060198.1"
                     /locus_tag="VO63_13565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="KKZ73236.1"
                     /transl_table=11
                     /translation="MTATLTSTPKRSVTGSLLTISAAQFLIALDFSVIFVAMPSMSADL
                     DLSGSAMQWVVSAYSVFFAGFLILGGRIADRIGPRTLFIASLGLFGLASLAGGLAAGAA
                     VLLLARAAQGVAAAALQPSILALLNTSFEAGRERTRAMAVWGTVGASGLAAGVVVGGLL
                     TTVSWRWTFFVNLPFALICVLAAPRFLAQADVRTAKPLNVLSAVVCTATVLASVFGLTF
                     AAGEGWAAPSTLISFAAAVVCLVVFVLRERSSSVPLIERSLRGTRTLLVGCGATALYMA
                     SVAGVEFYLVTLFLQENRDMAPLAAGIAFLPLAVCITLGNMIAGRIIPKVGVGISTPIA
                     FLVGAAGLVLLALGVHQTSYWAGLLPGLIVSGLGHGMIYTSMFVGGTRDVDDANQGVAG
                     ALMTTSQYAGGALGVAVLVILLGDQPADSRFLPGFLLAAAIAVVGALWGWRGFAGLRGK
                     DSAA"
     gene            complement(6605..7171)
                     /locus_tag="VO63_13570"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            complement(7168..8121)
                     /locus_tag="VO63_13575"
     CDS             complement(7168..8121)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_010060202.1"
                     /locus_tag="VO63_13575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="KKZ73237.1"
                     /transl_table=11
                     /translation="MTTSSHLRAPAFDPTLLALSEEVSEALAHGRPVVALESSVLSGFP
                     YPENLELAREMDAGIRAQGAVPARIALLGGKLRVGLDDALLQEFCAYGKVPKVSTRDIG
                     VTLAGGGPGGTTVSSSLLAAELAGIRVFAVAGIGGVHRDAPASYDISTDLVQFTRTRTA
                     VVCAGAKSMLHPQWTLEWLETAGIPVIGYRCDDFPAYLSVSSGVRNPHRLDDLSDVARA
                     TWAHWRSGNGTSVLVTHPIAEDDGIPSQEIADALAEATELAAREGITGPAVTPYLLKAI
                     AEATEGRTAAANRSVLKSTTVLAAEFAVHLAKEEQR"
     protocluster    8054..16475
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[13053:13428]"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      13054..13428
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     cand_cluster    8054..16475
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     gene            complement(8230..8835)
                     /locus_tag="VO63_13580"
     CDS             complement(8230..8835)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391897.1"
                     /locus_tag="VO63_13580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-hydroxychromene-2-carboxylate isomerase"
                     /protein_id="KKZ73323.1"
                     /transl_table=11
                     /translation="MLAEGPLEEAVEGLDVEIEWKPFELRAEPKATLRPEDPYLPEIWK
                     RAVYPMARRLGVDITLPTVSPQPYTRLAFEGWQFAVEHGLGDAYNHRMFRAFFQESLDL
                     GRLDVLVGLAEEIGLDGPAYRKALEDGTYYERHQDALRDAEAHRVQAVPTILVGDTRLE
                     GVPSTAQLRKAVLDERARLAASVTVEGVVCRADGTGCA"
     gene            complement(8946..9434)
                     /locus_tag="VO63_13585"
     CDS             complement(8946..9434)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391898.1"
                     /locus_tag="VO63_13585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="deaminase"
                     /protein_id="KKZ73238.1"
                     /transl_table=11
                     /translation="MTTAAKDHLTKQVEEAVRISREHVAAGGIPFSGIVVRHDGRVLGT
                     GFNRVREDRDASAHAEVVALRNATKQHGSFAVHGATLIASGEPCALCYQVALYFGVEHV
                     IYAADRRTAAQYGFDYSGSYRIYRADPTEWGIRTTHLPVEGHEVPFQEYLANRGSIHS"
     gene            complement(9443..9760)
                     /locus_tag="VO63_13590"
     CDS             complement(9443..9760)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018655304.1"
                     /locus_tag="VO63_13590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molecular chaperone"
                     /protein_id="KKZ73239.1"
                     /transl_table=11
                     /translation="MTWVYLGIAIVFEILFALGTNATQGFTKLWPSVLTLLAAAGGIYT
                     LSHALLELDVSVGYTIWTGIGGVGTVVFGAIIFKEKITLARLLSFASIIGGAIILRVTS
                     V"
     gene            complement(9834..10214)
                     /locus_tag="VO63_13595"
     CDS             complement(9834..10214)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_012894542.1"
                     /locus_tag="VO63_13595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug transporter"
                     /protein_id="KKZ73324.1"
                     /transl_table=11
                     /translation="MGWAWLLFSSLFEITFALSTEATHAFTRLGPSLLTAAAAACGIYT
                     LSQALKYVDVGVGYTVWAGIGGVGTVIFGTLIYDEPMTIWKVLAFVLIIGGGTTLRITD
                     KIAADKKVAEERVAEERAKATV"
     gene            10377..10832
                     /locus_tag="VO63_13600"
     CDS             10377..10832
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 77.9; E-value: 9.4e-24)"
                     /gene_kind="regulatory"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391901.1"
                     /locus_tag="VO63_13600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="KKZ73240.1"
                     /transl_table=11
                     /translation="MNNATTASPAPTSDQAVWDRVLTLHARVERELANALQRRHGIGLS
                     EYRALENLSSSPTSELRMQELADKIGLGQSSVTRLVERLKGAGYAFKDLCPSDKRGVYA
                     VITDEGRSRYVAARATYAEVLSGALNSQSADPALAATVASLRSARPV"
     gene            11200..12657
                     /locus_tag="VO63_13605"
     CDS             11200..12657
                     /NRPS_PKS="Domain: AMP-binding (10-389). E-value: 2.6e-64.
                     Score: 209.1. Matches aSDomain:
                     nrpspksdomains_VO63_13605_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     256.9; E-value: 5.1e-78)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_010060210.1"
                     /locus_tag="VO63_13605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fatty acid--CoA ligase"
                     /protein_id="KKZ73241.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-65, bitscore:
                     211.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPSLAQTIAAHAERQPSSTALVLNDEQVTYGELADLVTLLSER
                     IGAADLPDDRPVCIPARKDPATVALMLAAFGRPLVVLAPSAELGDDALDRICRQARVSA
                     RLSATADGTLTVRAQAGDEAAAEGFGRPTADAARLLLTTSGSTGTPKLVPIGTAAFDAF
                     AAWAVEEFRITAADSSLSYAPLNFDLALLDVWTFLGAGARVVLVDREKATDAPHLRSLV
                     SGGAVTFVQGVPLLYRLLTEGEGAHEGVREVVLTGDAVPQDLLERAAESFPRARFHNVY
                     GCTETNDSFLHRVDPRTARGKIPIGRPLPGVEAGVLDDEGRALTGPGTGELVVRTPFQT
                     TGYLQESLNPDVFVVREGRVFYRTGDIVTRDADGLHFLEGRSDWQVKVRGVRTNLQEVE
                     SVLAQHPDVEEAAVIALPDPEAGVRLHARLTKRAGAGLNSLAVRSYAGANLPRHAIPSS
                     VRISEIPLPRTSTGKPDRNKIKEEISA"
     aSDomain        11230..12366
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_VO63_13605_AMP-binding.1"
                     /evalue="2.60E-64"
                     /label="VO63_13605_AMP-binding.1"
                     /locus_tag="VO63_13605"
                     /protein_end="389"
                     /protein_start="10"
                     /score="209.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AAHAERQPSSTALVLNDEQVTYGELADLVTLLSERIGAADLPDDR
                     PVCIPARKDPATVALMLAAFGRPLVVLAPSAELGDDALDRICRQARVSARLSATADGTL
                     TVRAQAGDEAAAEGFGRPTADAARLLLTTSGSTGTPKLVPIGTAAFDAFAAWAVEEFRI
                     TAADSSLSYAPLNFDLALLDVWTFLGAGARVVLVDREKATDAPHLRSLVSGGAVTFVQG
                     VPLLYRLLTEGEGAHEGVREVVLTGDAVPQDLLERAAESFPRARFHNVYGCTETNDSFL
                     HRVDPRTARGKIPIGRPLPGVEAGVLDDEGRALTGPGTGELVVRTPFQTTGYLQESLNP
                     DVFVVREGRVFYRTGDIVTRDADGLHFLEGRSDWQVKVR"
     misc_feature    11323..11325
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       11617..11664
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VO63_13605_0001"
                     /evalue="2.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="VO63_13605"
                     /protein_end="155"
                     /protein_start="139"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LLTTSGSTGTPKLVPI"
     CDS_motif       12337..12396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_VO63_13605_0002"
                     /evalue="1.20E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="VO63_13605"
                     /protein_end="399"
                     /protein_start="379"
                     /score="21.0"
                     /tool="antismash"
                     /translation="GRSDWQVKVRGVRTNLQEVE"
     gene            12654..12923
                     /locus_tag="VO63_13610"
     CDS             12654..12923
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147:putative acyl carrier protein (Score: 61.2;
                     E-value: 1.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391903.1"
                     /locus_tag="VO63_13610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine attachment site family
                     protein"
                     /protein_id="KKZ73242.1"
                     /transl_table=11
                     /translation="MSAPTRDIAGEIRAHLLTQYLKGEDVSAEDLPGDYELIESGVVDS
                     LGLVKLIQYIANTYGVPVDDIEIGPDNFRTIDAITKTITDNTSL"
     gene            13054..13428
                     /locus_tag="VO63_13615"
     CDS             13054..13428
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_010060207.1"
                     /locus_tag="VO63_13615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine synthase"
                     /protein_id="KKZ73243.1"
                     /sec_met_domain="ectoine_synt (E-value: 9.2e-33, bitscore:
                     103.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTRTLEDVTPVEWGNGTSHRLLTETDKMGFTVCKTLVRKGTNSA
                     LQYRNHLEACYCVAGSGAVVHKDGTVFKINPGTIYVLDEHDPHYLIASEHEDLHLISVF
                     NPPLTGTEQHRLSEDGFSQY"
     gene            13538..14665
                     /locus_tag="VO63_13620"
     CDS             13538..14665
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 329.5; E-value:
                     4.7e-100)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391905.1"
                     /locus_tag="VO63_13620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="KKZ73325.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.8e-18, bitscore:
                     55.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.4e-27, bitscore:
                     86.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.3e-31, bitscore:
                     97.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRDGPLTELVAPYADVLNADLAELDAGSVFSRAKWQAIKDSGI
                     LRTPFKEEHGGSGRSFTETMKVLEGLGYHSRDAGVSFSTSTQIVSLATPLEKFGSAGLK
                     ARYLPRILSGEAITAHAITEESGGSDAMNITTVAVREDDHYVVDGGKMFITNAPVADLF
                     LLYVRTGKPGPFGLTCLLVERDTPGLEIGEPLDKLGLRTSPLGRLTFDRLRVPVTNRVG
                     AEGGGFLVLDYVMKREILYAFSITLGEMRHRLDTVIRFATERTQFGQPIASYQAVSHKI
                     VEMRIAVETAAKWLADTGAKAERGEDISLDLASTKIVVSEANVKTALDAVQIHGGRGVL
                     TSHGIERDLRNSVAGTIYSGSSEIQRNRMAALLGL"
     gene            14684..15403
                     /locus_tag="VO63_13625"
     CDS             14684..15403
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391906.1"
                     /locus_tag="VO63_13625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglutaminase-like superfamily protein"
                     /protein_id="KKZ73244.1"
                     /transl_table=11
                     /translation="MSIALDELHALTRPTDFLDHESDEVQNFVDSVVKDRAADRRENAV
                     KLYYAVRDGLDYEVYDTDLSPEGLKASSVLSAGQGFCLHKSVVYAAAVRALGIPSKLVY
                     GDVRNHLASPRLIAHIGGDVFFHGLTQVYLDGRWVKATPVFNKLLCRLYGMEALEFDGT
                     ADSLHHPYAGQEGKGSMEFLKDHGSFDDVPYDFVISTMRAKHPNFLSSEGSGTVKGGSL
                     AAEADTVTAADPADSGR"
     gene            15416..16225
                     /locus_tag="VO63_13630"
     CDS             15416..16225
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020391907.1"
                     /locus_tag="VO63_13630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="maleate cis-trans isomerase"
                     /protein_id="KKZ73245.1"
                     /transl_table=11
                     /translation="MSSATTSPSDGWDATTRIGVVVPSADIGPEAELQAVAPDSVTIHA
                     SRIDFGGMLPGGHMVAEKIPQDPITAFVEPPAVDNAVKLLADSPLHALVLGFTSSSYVL
                     GVDGENALYERLAPVTRGIPVTGTARAAVAGFRALGAERIAIVNPPWFDDKLSTQGQEY
                     FEAQGFTVVHHGPVGLPSEQTAITPQNLSEWIRTTVADARPEAILVAGNGIRAVGTIRG
                     LEDELGFHVLTANQAVLWHALHLAGAAAAAARVTDYGRLFRAVPKEA"
     gene            16230..16475
                     /locus_tag="VO63_13635"
     CDS             16230..16475
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018489549.1"
                     /locus_tag="VO63_13635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KKZ73246.1"
                     /transl_table=11
                     /translation="MLPADGYVAVFTTPEGDVYRTPLVCWRADGPHVYGVTLHKGGLRR
                     AEELPGFTRYAVKPDCSCDATAPAVPAPVDRQLASR"
     misc_feature    16233..16235
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ctacagtccg acgtcgcggg cccgcaggtc ggcctgcgtc tcgcggcgga cgagcagccg
       61 tcccgccccc gccgcgaccg ccaccaccgg cgggcggccg accaggttgt acgaggaggc
      121 catcgacagg tggtacgcgc ccgccaccgg aaccgccagc agatcgcccg ggcgcacgtc
      181 cgagggcagc ggcacgtcct cggcgaggac gtccccggcc tcgcagtgcc gccccaccac
      241 cgtcgcccgc cgcggaccgg cggccgaccg gcgcccgatg agccggggcg cgtaccgcac
      301 cccgtacagc gccgggcgcg ggttgtcgct catcccgccg tccacggcga cgaagaagcg
      361 ctccggcgtc gccttcaccg cgaggacccg gtagacgacc accccggccg ggcccgagat
      421 ggcccgcccc ggctcgacga tcagccgggg cacgggcagt ccggcgcccg cgcagctctc
      481 ggccagctcg gcccgcaccc ggcgggccag ggcggccggg tcgagggcgc ggtcgccggg
      541 gcggtacgcg atgccgtgcc cgccgccgag gtcgagctcg gacagcacca cgccgtgcgc
      601 gtcccgggtg cgggccatca gccccaccag ccgtcggacg gcgaccagat acggcttgac
      661 gtccgtgatc tgcgagccga ggtggcagtg cagcccggtg agccgcagcc ggggctggcc
      721 gaggaggcgg gcgatcgcgt gctgggcgtg gccgtcgcgc agcgacaggc cgaacttctg
      781 gtcgtcggag ccggtgcgga ccttggcgtg gccgcccgcg ctgatgccgg gggtcacccg
      841 cagcatcacc cgctgccgct cgcccgggcc gacggcggcg gcgatccgcg cgatctcggc
      901 ggggctgtcg atgacgatcc ggccgacgcc gaggcgcagc gcggtccgca ggtcctccgg
      961 ggacttggcg ttgccgtgca gcaggatccg ctcgggcggg aagccggtgg tgacggcgag
     1021 ttcgagctcc ccggccgagc agacgtcgag gccgaggccc tcctcctcga cccagtgggc
     1081 gagggcgcgg cacaggaacg ccttggccgc gtagtggaca tcggccccgg ggaaggcgtc
     1141 ccggtaggcg cggcagcggt cgcggacctc ggcctcgtcg aggacgtaga cgggagtgcc
     1201 gtggctctcg gcgagctcgt cgagggccac tccgccgacg tacaggcgcc cgtcgggccg
     1261 ctcgaccgta cgggcgggcc agacggacag gtcacccgcg gggacggcga ccggcggcag
     1321 gggcgtcacg gtcatctcgg cgccgccctt cagcgcgcgg aggcggtcag ggggcgggtg
     1381 gcggcccttc ccgggcatgg cccgggcacg gccggaccag gggcggccgg agccggaggg
     1441 accgggccag gggcggccgg agccggaggg accgggccag gggcggccgg agccgggcgg
     1501 acctgagcgg ggatggccgg agccgggcgg atcggagcgg gggcggccgt cagcgtcggg
     1561 tcgacggtca ggatgtcgac gcccagcggg cggacgagcg cccgcagcgc gggctcggag
     1621 agcgccgtcc acggctgctc ggcgccgagg acggagcgga gccgggcggg cgtcgtgaac
     1681 gcgaccgccg tacgggctcc gacgggggtg cggaagaggc gggcggcgca gccgtgggcg
     1741 accggccgga cggggacgca gagccgtccg gccggcgcat gttcagccgg ctcgggatcg
     1801 tcgccgtaca ggtctccgca ctggacgtgg gtcatggttc ctcccggaac gggcgtgcgt
     1861 cccggcgtcg ttcgcgccgg ggccgacccc gaagctacgc ccgccgcgtc cgcccgggag
     1921 ctcccctgac gtacccctga cggtggtttg acgcgaatcg tgcgctgaaa cggccaggtc
     1981 ggccgaggtg cgacgggcgg gccgcggccg gtccgtgacg agattgcgcg atcacctcga
     2041 tccgcgcgcg gtgagctggc acgcttgccg tcgtgacgta cgtcgtaacc gtggaaacgc
     2101 gcatacccgg cggtgctccg gagctggacg agctgagcag ggtcggggcc gggacgctgc
     2161 tggagcgggg gttcgactcc gtggcggggg tcgaggggcc cgacggggtg gaggtcgacg
     2221 tcctcgacgt cgtggtcggg gtccatccgg gcggggcgat cctgaaggtg ttcgtcgagg
     2281 cgccctcgct ggaggtcgcg gaggacgcgg tcggctccgt gacccaggag gtgctcgaac
     2341 gctccgaggt gctggccgag tgggtggtgg agagcagcga ggtcaagctg cacaccgatc
     2401 tcgcccggga gagcctggag gccgccgacg ggcccgacgc cccgcccagc gatccgcagg
     2461 tgcggcgcgc ccagcacgcc ctgaaggccg ccgagacctt cgagacggcc gaggagacgc
     2521 acgaccccga ggcggagatc cgggccatgg ccgcgcggct gcggtccttc accccggcca
     2581 cgttcggggt ggccgacccc gtggacgagt tcggcgtcgg gcccggcggc gccgaactgg
     2641 ccgccggtgc cctggtgtac ggcgccgagg tgctgatcga cgagctgtac gacgacgtgc
     2701 aggcgctcgc cgatgaggac acgaacgtcg ccggctgcga gggccacctc tggcacctgg
     2761 accagctgcc ggcgcgctac gcctcccggt acgacgagct gttcgcccgc cgcttcctgg
     2821 tcaccgccgt cgccctcacc acccgtttca ccgacggcgg cttcgagcgg ctcggctgcc
     2881 tggccgagga actggtcctg aagttcctgc tggaacaggc gcacgtcacc ctcgacctct
     2941 acggcctcct ggacgacgag gtcacggcgg cgctggagtg cttcgccacg gaggtctacg
     3001 aggacgggga cttcgagtgg ctcttcgacg gcggggcgga gggggccgag cgggccgagg
     3061 aggcggacgg agccgacggg ccggacggac ccgcccccgg cttcggcacc tggttcaccc
     3121 ctttcggtga ggaccgttac gtgcacccgt acgcggccga cgaacacgtc caggagcccg
     3181 aggacgcgta gggcgcccgg acgggcccgg tcccgcggtc cggaagtcga cccggtccgc
     3241 cgccccggaa gtcgacccgg gcggtccggc tcagtaggct cggcgggccg tccgggagaa
     3301 ggagaagcag tgttcgtcaa ggtgtgcggg ctcgccacga ccgccgacat cgacgtggcc
     3361 gcggaggccg gggcggacgc gatcggcctg gtgatcagcc ggaccagcgt ccgcggcctc
     3421 gactgggacc gggcggtcgc cctcgcggcc cacgtgccct cccacgtacg gtccgtcctc
     3481 gtcgtcaacg acacggccgc cgccgacgcc gcccgcgcgg cgaacgagct cggcgtcgac
     3541 gcgctccagc tgcacggcac gtacaccagg gccgacttcg acgaggcggc ccgcaccttc
     3601 ccccggcttt ggcgggccac ctccctgaac gagaagcccg acacccgcgt cggcgcctac
     3661 ggcgaggagg tgctgctgct cgactcgccg cgcgccggat ccggcgcccg ctgggacctc
     3721 tccctgctcg acgcggcccg ccccgagggc gcctggctcc tcgccggcgg cctcggcccc
     3781 gacaacgtcg ccgaggcgat ccggcaggcc gacccctggg gcgtcgacgt ctccagcggc
     3841 gtggagtccg cccccggcgt caaggaccac gcccgcatcc acgccttcgt cacggcggcg
     3901 aggaccgcgg cgggccggga ccatggacag cctcaggacc ggggccggga gcaggaccgg
     3961 ggccggtagc agggcccggg ctagggctcc cggtcgccca cccagcgcca gaagtcgacc
     4021 gtcatccgct cgtagcggat gccgaactcc agggcctcgc gccggccccg gcccgccccg
     4081 gccctaccga cgagttcggg ccggacgcgg gcatgaccgt gccccggcgg cgggggacgg
     4141 cgcgccgggg cacggggatc gggggagaga gcgggagggg cgggcgggag gctgccggtg
     4201 gggtgctggg tcgtgtccgg aaggtcccga cacgacctag cgcgcgccga agagcgtgcc
     4261 gtggcgttcg tcgccccact cgcccgccgc gcgcagcccg taccagagca cggactggtt
     4321 ggcggtgacg accgggacgt ccagcacctt ctcgaggagg gggaccaccg cctggctgcg
     4381 gaagccgctg ccgggcacga gcaccccgtc cgcccggccg cccgtcgcct cgaaggcggc
     4441 ggtggtctgg cgcagcacct cgtcggggtc gatcgcccag cgggcaccct cgtcgaaggc
     4501 gttgtacggc gggacgtgcg cccactccgg gccgagctcg aaggggtgga cgaacacctc
     4561 ctcgacgccg tgccccgtca ggtacgcctc ggcggcgcgg tgcgtcggcg gggtgaacca
     4621 gggcggcatc accaccagcg ggcgccgtac ggagacggcg gccagcgcct cggtcagggc
     4681 ctggcccgag gtgtacaccg gcgtgccgtg ggagtgcgcg agggcggcct cggcgaactc
     4741 ggcgtcgaat ccctccccgc cgaagaagct cggcgagccg aagcagaacg cgatccggtc
     4801 gaccccgagc cggccgagga agtccagcga gcggaccacg tcgggcgcgt cggcgagcag
     4861 cgtggccgtg ctgccggtgt actcggcgtc gtcgagccgc gggcactcga agcgggcggt
     4921 gtggacgctg gtgccctccg gggccgtccg ccagatctcg gtctcgggga cgggatcgtt
     4981 gtggatgacg aggatgccca gccgggtcat gccgccgagt cctttccgcg caggcccgcg
     5041 aagccccgcc agccccacag ggcgcccacc acggcgatgg cggcggccag caggaagccg
     5101 ggcaggaagc gggagtcggc cggctggtcg cccagcagga tgaccaggac ggccacgccg
     5161 agcgcgccgc ccgcgtactg actggtcgtc atgagggcgc ccgcgacgcc ctggttggcg
     5221 tcgtcgacgt cccgggtgcc gccgacgaac atcgaggtgt agatcatgcc gtggcccagg
     5281 ccggagacga tcaggcccgg cagcaggccg gcccagtacg aggtctggtg gacgccgagg
     5341 gcgagcagca ccagaccggc cgcgccgacc aggaaggcga tcggcgtgct gatcccgacc
     5401 cccaccttcg ggatgatcct gccggcgatc atgttgccga gggtgatgca gaccgccagc
     5461 ggcaggaagg cgatgccggc ggcgagcggg gccatgtccc ggttctcctg gaggaagagc
     5521 gtcaccaggt agaactcgac gcccgccacg ctggccatgt acagcgcggt cgcgccgcag
     5581 ccgacgagca gggtgcgggt gccgcgcagc gaccgctcga tcagcggcac ggagctgctg
     5641 cgctcccgca gcacgaacac caccaggcag accaccgcgg cggcgaagga gatcagcgtc
     5701 gacggcgcgg cccagccctc gcccgcggcg aaggtgaggc cgaagaccga ggcgagcacg
     5761 gtcgccgtgc acaccacggc gctgaggacg ttcagcggct tcgccgtgcg cacgtccgcc
     5821 tgggcgagga agcgcggcgc ggcgagcacg cagatcagcg cgaagggcag gttgacgaag
     5881 aaggtccacc gccaggacac cgtcgtgagc aggccgccca cgacgactcc ggcggccaga
     5941 ccgctggcgc cgacggtgcc ccacacggcc atcgcccggg tgcgttcccg gcccgcctcg
     6001 aagctggtgt tcagcagggc gaggatcgag ggctgcagcg cggcggcggc gacgccctgc
     6061 gcggcccggg cgagcagcag cacggccgct ccggccgcga ggccgccggc cagcgaggcc
     6121 aggccgaaga ggccgagcga ggcgatgaac agggtgcggg ggccgatccg gtcggcgatc
     6181 cggccgccga ggatcaggaa gccggcgaag aacacgctgt aggcgctgac cacccactgc
     6241 atcgccgacc cggacaggtc caggtccgcg ctcatgctgg gcatggcgac gaagatgacg
     6301 gagaagtcca gcgcgatcag gaactgcgcg gcggagatgg tcagcaggct gcccgtgacg
     6361 ctccgcttcg gtgtggaggt gagtgtggct gtcatgtccc ctggtctcta cggttcgctg
     6421 gtacgggctt ctagtgcggt gcggacagcg gcggcgcggt cggcggcggt gcggacagcg
     6481 gcggcgcggg cagcggtgtg gcggacggcg gtgctgcggt cagcgtgccg aggacggcgg
     6541 tgagcgcgtc gacggagcgg acgacggtgt gcgcccccgc ctcgtgcagc gcctcctcgg
     6601 tggcgacgcc gtaggtgacg ccgaccgcgc gcatccccgc cgagcgggcc atccgcatgt
     6661 cgtcgacggc gtccccgacc accacgcagg cctccgggcc gcggcccagt tcccgcgcgg
     6721 ccagcagggc caggtccggg tgcggcttgc cgcgctcggc catgccgtgg cagacgacgg
     6781 cgtggaacag ctcgtacagt ccggcgggct tgaggagttc ctccgcgctg ggcctgatct
     6841 tgctggtcac gatggcgatc tggtgcccct cgtcgcgcag cccttcgagg agggcgcgga
     6901 tgccggggaa gaccagctcg cgggcgcgcg gcacggcctg ctcgcggaag aggcggcgga
     6961 agagttcgac cgcggcggtc acctcggcgt ggtcctcggg cagctccgtc agctgggcga
     7021 aggaggcggc cagcggccgg ccgatggtcg cccgcacccg cgcgtcggag gcgctgcggc
     7081 cccgttcggc gagggtcgcg tggagggtgt cggcgatggc ggacggcgtg tcgagcaggg
     7141 tgccgtccag gtcgaagagg accgcgctca ccgctgctcc tccttggcga ggtggacggc
     7201 gaactcggcc gccagcacgg tggtcgactt cagcaccgag cggttggcgg cggcggtccg
     7261 gccctcggtg gcctcggcga tggccttgag caggtacggg gtgacggccg ggcccgtgat
     7321 cccctcgcgg gcggcgagct cggtcgcctc ggcgagggcg tcggcgatct cctgcgaggg
     7381 gatgccgtcg tcctcggcga tggggtgggt gacgaggacg ctggtgccgt tgccggagcg
     7441 ccagtgggcc caggtggccc gggcgacgtc ggacaggtcg tcgaggcggt gcgggttgcg
     7501 caccccgctg gagaccgaca ggtaggcggg gaagtcgtcg cagcggtagc cgatgacggg
     7561 gatgcccgcg gtctccagcc actccagggt ccactggggg tgcagcatcg acttcgcccc
     7621 ggcgcacacc accgcggtcc gcgtacgggt gaactggacg aggtcggtgg agatgtcgta
     7681 gctggcgggg gcgtcgcggt ggacgccgcc gatgccggcg accgcgaaga cccggatccc
     7741 ggccagttcg gcggcgagca gcgacgagga cacggtggtg ccgccggggc cgccgcctgc
     7801 gagggtgacg ccgatgtccc gggtggagac cttcggcacc ttcccgtacg cgcagaactc
     7861 ctggaggagc gcgtcgtcca ggccgacccg gagcttcccg ccgagcagcg cgatccgggc
     7921 cggtacggcg ccctgggcgc ggatcccggc gtccatctcc cgggccagct ccaggttctc
     7981 cgggtacggg aagccggaca ggacggagga ttcgagggcc acgacgggtc tgccgtgggc
     8041 cagggcttct gacacctcct cgctgagtgc gagcagagtc gggtcgaacg ccggcgcacg
     8101 aaggtgcgag gaggtggtca tgaaggatcc cctttgtgtt gcgtggtgct gtgctgtgcg
     8161 gtgctgtctc tctggttctc tctgaatttc tccggacgac gggtggagac gaccggtgaa
     8221 gcggacgcgc tacgcgcagc ccgtgccgtc ggcgcgacag accacgcctt cgaccgtgac
     8281 cgacgcggcc agcctggcgc gctcgtccag gacggccttg cgcagctgtg cggtgctggg
     8341 cacgccctcc agacgggtgt cgccgacgag gatggtcggg acggcctgga cgcggtgggc
     8401 ctcggcgtcg cgcagggcgt cctggtggcg ctcgtagtac gtgccgtcct ccagggcctt
     8461 gcggtacgcg gggccgtcga ggccgatctc ctcggcgagg ccgacgagga cgtcgagccg
     8521 gccgaggtcc aggctctcct ggaagaaggc ccggaacatg cggtggttgt acgcgtcgcc
     8581 gaggccgtgc tcgacggcga actgccagcc ctcgaaggcc agccgggtgt agggctgcgg
     8641 cgagacggtg ggcagggtga tgtccacgcc caggcggcgg gccatcgggt agacggcgcg
     8701 cttccagatc tcgggcaggt acgggtcctc cgggcggagg gtggccttgg gctcggcgcg
     8761 gagctcgaag ggcttccact cgatctcgac gtcgagcccc tcgacggcct cctccagcgg
     8821 gccctcggcc agcatgcaga agggacacac gtagtcggac cagatctgga cgcgtacctt
     8881 ggcgggggcc tcggcgtccg tggcggcggc gtccgtggtc ccggtggtcc cggtcgtctc
     8941 ggtgctcacg agtggatgct ccctcggttg gccaggtact cctggaacgg cacctcgtgt
     9001 ccctcgaccg ggaggtgggt ggtcctgatg ccccactcgg tcgggtcggc gcggtagatg
     9061 cggtacgagc cggagtagtc gaagccgtac tgggccgcgg tcctgcggtc ggcggcgtag
     9121 atgacgtgct cgacgccgaa gtacagggcg acctggtagc acagggcgca gggctccccg
     9181 gaggcgatca gggtcgcccc gtggacggcg aacgacccgt gctgcttcgt ggcgttgcgc
     9241 agggcgacca cctccgcgtg ggcggaggcg tcgcggtcct cgcggacgcg gttgaagccg
     9301 gttcccagga cgcggccgtc gtggcggacc acgatgcccg agaaggggat gccgccggcg
     9361 gcgacgtgtt cgcggctgat ccggactgct tcttccacct gcttggtcag gtggtccttg
     9421 gctgcggtgg tcatgagcgg gctcagacgg aggtcacgcg caggatgatg gcgccgccga
     9481 tgatcgacgc gaaggacagc agccgggcga gggtgatctt ctccttgaag atgatggcgc
     9541 cgaagaccac cgtgccgacg ccgccgatgc cggtccagat cgtgtagccg accgacacgt
     9601 ccagctccag cagggcgtgg gacagggtgt agatgccgcc ggccgcggcg agcagggtca
     9661 gcacgctggg ccacagcttg gtgaagccct gtgtggcgtt ggtgccgagc gcgaagagga
     9721 tctcgaagac gatggcgata ccgaggtaga cccaggtcat gggagcggct ctctctactg
     9781 gaaaaggagg gtggggaggc ggggccggaa agcggtggag cgggggagcg gggtcagacc
     9841 gtggccttgg cgcgctcttc cgcgacgcgc tcctcggcga ccttcttgtc cgcggcgatc
     9901 ttgtccgtga tgcgcagcgt ggtgccgccg ccgatgatca ggacgaaggc gaggaccttc
     9961 cagatggtca tcggctcgtc gtagatcagg gtgccgaaga tgaccgtgcc gacgccgccg
    10021 atgccggccc agaccgtgta gccgacgccg acgtcgacgt acttgagggc ctgggagagc
    10081 gtgtagatgc cgcacgcggc ggccgcggcc gtgaggagcg aggggccgag gcgggtgaag
    10141 gcgtgggtgg cctcggtgga gagggcgaag gtgatctcga agagcgacga gaacagcagc
    10201 caggcccagc cgatgttctg gttcttctgt gtctgctcgg cggacactat gcctccattg
    10261 ttgtttgtgc gtgcaagttc cttaggatca tgaagctcct aagtacggca cggagttagc
    10321 taggatcttg catggtcata taacctgttg tcaaaccccc ttttgaggag aggtacatga
    10381 acaacgccac caccgcgtct cccgccccca cctcggacca ggccgtctgg gaccgcgtcc
    10441 tcaccctcca cgcgcgggtg gagcgggagc tcgccaacgc gctccagcgc cggcacggca
    10501 tcggcctctc ggagtaccgg gcgctggaga acctgtcctc ctcacccacc agcgagctgc
    10561 gcatgcagga gctcgccgac aagatcgggc tggggcagtc ttcggtcacc cggctcgtcg
    10621 agcggctgaa aggtgctggt tacgccttca aggacctctg tccctcggac aagcgagggg
    10681 tctacgcggt gatcaccgac gagggccgca gccgctatgt ggccgcccgc gccacctacg
    10741 cggaagtgct ctccggcgcg ctcaactcgc agagcgccga ccccgcgctc gcggccaccg
    10801 tggcctcgct gcgcagcgcc cgccccgtgt aggcgacgcc ctcccgggcc cgtcccgagc
    10861 gcacccccgt ccccccgggc acgcctccgt cctccccgaa ccctccccga accgccggcc
    10921 gtcgcctccc gccgtctcct tcccccggag acggaagggc gcggcctttc tgcgttcaca
    10981 cgcccgcagc accgccttaa tgatcttgac ttagattgtt agttgtatgt gcaagcggtg
    11041 aggtaggtca caacgcgacc gctcggtata tgcttgaccc tgcatggaaa ctcggtaatg
    11101 tctggtccgg cgcagatcgg ttcgaacagg gatcgaacag aaccccgaac gaatcgaacg
    11161 gtgcttggcc cagtcttttc cagaccatgc gggggaaacg tgccatcgcc cagccttgcc
    11221 cagaccatcg ccgcgcacgc cgagcggcag ccgtcctcga cggcactcgt gctcaacgac
    11281 gagcaggtga cctacggcga actcgccgac ctggtgacgc tcttatcgga gcggatcggg
    11341 gcggcggacc tcccggacga ccggccggtc tgcataccgg cccggaagga cccggcgacc
    11401 gtcgccctga tgctcgccgc gttcggccgg cccctggtcg tcctcgcacc gtccgccgaa
    11461 ctcggcgacg acgcgctcga ccggatctgc cgccaggccc gggtctcggc gaggctgtcg
    11521 gccaccgccg acggcacgct caccgtccgg gcccaggccg gggacgaggc cgccgcggag
    11581 ggcttcggcc ggccgacggc cgacgcggcc cgcctgctcc tgaccacctc cggctcgacc
    11641 ggcaccccca aactggtgcc gatcggaacc gcggccttcg acgccttcgc cgcctgggcc
    11701 gtcgaggagt tccgcatcac cgccgcggac agctcgctgt cctacgcgcc gctcaacttc
    11761 gacctggccc tgctcgacgt gtggaccttc ctcggcgcgg gggcgcgggt cgtcctggtc
    11821 gaccgcgaga aggccaccga cgccccgcac ctgcggagcc tcgtctcggg cggtgcggtc
    11881 accttcgtcc agggggtgcc gctgctctac cgcctcctca ccgaggggga gggggctcac
    11941 gagggggtgc gcgaggtcgt cctcaccggg gacgccgtac cgcaggacct cctggaacgt
    12001 gcagcagaat cgtttccgcg agcgcgtttc cacaatgtct acgggtgcac ggagaccaac
    12061 gacagcttcc tgcaccgcgt cgacccgcgc accgcgcggg gcaagatccc catcggccgg
    12121 ccgctgcccg gcgtcgaggc cggcgtcctc gacgacgagg ggcgggcgct gaccggcccg
    12181 ggcaccggcg aactcgtcgt ccgcacgccc ttccagacca ccggctacct ccaggaatcc
    12241 ctgaacccgg acgtgttcgt ggtccgcgag ggccgggtct tctaccgcac cggcgacatc
    12301 gtcacccgcg acgccgacgg cctccacttc ctcgaaggcc gctccgactg gcaggtcaag
    12361 gtgcgcggtg tgcgcaccaa cctccaggag gtcgagtccg tcctcgccca gcaccccgac
    12421 gtcgaggagg cggccgtcat cgccctcccc gacccggagg ccggagtcag gctgcacgcc
    12481 cgcctcacca agcgggccgg agccggtctc aactccctgg ccgtccgctc ctacgcggga
    12541 gcgaacctgc cccgccacgc cattccgtcc agcgtccgca tcagcgagat ccccttgccg
    12601 cgcacctcga ccggcaagcc ggaccgcaac aagatcaagg aggagatcag cgcatgagcg
    12661 cccccacccg tgacatcgcc ggagagatcc gcgcccacct gctcacgcag tacctgaagg
    12721 gcgaggacgt ctccgccgag gacctgcccg gcgactacga gctgatcgag tcgggagtcg
    12781 tcgactcgct gggcctcgtg aagctcatcc agtacatcgc gaacacctac ggcgtgcccg
    12841 tcgacgacat cgagatcggg ccggacaact tccgcacgat cgacgccatc acgaagacca
    12901 tcacggacaa cacgtccctc tgagcgtcct tacggaccct ctccggacgt ctctccggaa
    12961 cctctccgga cgtctctccg cacgtctctg cacgtcaccg cacgtctccg cacgttcctt
    13021 tcaggtatcc gcacctcctc agaggagtca gccatgttca cgcgcacgct cgaggacgtc
    13081 accccggtcg agtggggcaa cggcaccagc caccggctgc tgaccgagac cgacaagatg
    13141 ggcttcaccg tctgcaagac gctggtccgc aagggcacca actccgccct ccagtaccgc
    13201 aaccacctgg aggcctgcta ctgcgtggcc ggctccggcg cggtcgtgca caaggacggc
    13261 accgtcttca agatcaaccc gggcaccatc tacgtcctcg acgagcacga cccgcactac
    13321 ctcatcgcct ccgagcacga ggacctgcac ctcatctcgg tcttcaaccc gccgctgacc
    13381 ggcacggagc agcacagact ctccgaggac ggcttctccc agtactaggc agccccacgt
    13441 tccccggccg ggccttcggc gcgacacggc ccggccggga acgcccgccc cgcccgcacc
    13501 aggaaggaag accgtgaccg ccgatgtact gccgcccctg accgaccggg acggcccgct
    13561 caccgaactc gtcgccccct atgccgacgt cctgaacgcc gacctcgcgg agctcgacgc
    13621 gggatccgtc ttctcccgcg ccaaatggca ggcgatcaag gacagcggca tcctgcgcac
    13681 ccccttcaag gaggagcacg gcggcagcgg acgcagcttc accgagacga tgaaggtcct
    13741 ggaaggcctc ggctaccact cccgtgacgc cggcgtctcc ttctccacct ccacccagat
    13801 cgtgtccctc gccaccccgc tggagaagtt cggctccgcc ggactgaagg cccggtacct
    13861 gccccgcatc ctctccggcg aggccatcac cgcccacgcc atcaccgagg agtccggcgg
    13921 ctccgacgcc atgaacatca ccaccgtcgc cgtccgcgag gacgaccact acgtcgtcga
    13981 cggcggcaag atgttcatca ccaacgcccc cgtcgccgac ctcttcctgc tgtacgtgcg
    14041 caccggcaag cccggcccgt tcggcctcac ctgcctgctc gtcgaacgcg acaccccggg
    14101 cctggagatc ggcgagcccc tcgacaagct gggcctgcgg acctcgcccc tcggccggct
    14161 caccttcgac cggctgcgcg tcccggtgac caaccgggtc ggcgccgagg gcggcggctt
    14221 cctcgtcctg gactacgtga tgaagcggga gatcctctac gccttctcca tcaccctcgg
    14281 cgagatgcgc caccggctcg acaccgtcat ccggttcgcc accgagcgca cccagttcgg
    14341 gcagcccatc gcgagctacc aggccgtcag ccacaagatc gtcgagatgc ggatcgccgt
    14401 cgagaccgcc gcgaagtggc tcgccgacac cggcgccaag gccgaacgcg gcgaggacat
    14461 ctccctcgac ctggcctcca ccaagatcgt cgtctccgag gccaacgtga agaccgccct
    14521 ggacgccgtc cagatccacg gcggccgcgg cgtcctcacc tcgcacggaa tcgagcgcga
    14581 cctgcgcaac tccgtcgccg gaaccatcta ctcgggcagc agcgagatcc agcgcaaccg
    14641 catggccgcc ctcctcggac tctgagctag gagctctccc gtcatgagca tcgccctcga
    14701 cgaactgcac gcactgaccc ggcccacgga cttcctcgac cacgagtccg acgaggtcca
    14761 gaacttcgtg gactccgtcg tcaaggaccg tgccgccgac cggcgcgaga acgccgtgaa
    14821 gctctactac gccgtccggg acggcctcga ctacgaggtc tacgacaccg acctcagccc
    14881 cgagggcctc aaggcctcca gcgtcctcag cgccggccag ggcttctgcc tccacaagtc
    14941 ggtcgtctac gcggccgccg tccgcgccct gggcatcccg tccaagctgg tctacggcga
    15001 cgtccgcaac cacctcgcca gcccccggct gatcgcccac atcggcggcg acgtcttctt
    15061 ccacggactc acccaggtct acctggacgg ccgctgggtc aaggccaccc cggtcttcaa
    15121 caagctgctc tgccgcctgt acggcatgga ggccctggag ttcgacggca ccgccgactc
    15181 cctccaccac ccctacgcgg gccaggaggg caagggctcc atggagttcc tcaaggacca
    15241 cggctccttc gacgacgtcc cgtacgactt cgtcatctcc accatgcgtg ccaagcaccc
    15301 caacttcctg agcagcgagg gaagcggcac ggtcaagggc ggctcgctgg ccgccgaggc
    15361 cgacaccgtc accgccgccg accccgccga ctccggcaga taaggacccg agagcatgag
    15421 cagcgccacc acctcgccgt ccgacggctg ggacgccacc acccgcatcg gcgtcgtcgt
    15481 cccctcggcc gacatcggcc ccgaggccga actccaggcc gtggccccgg actcggtgac
    15541 gatccacgcc tcccgcatcg acttcggcgg gatgctcccc ggcgggcaca tggtcgcgga
    15601 gaagatcccc caggacccca tcacggcgtt cgtcgagccc ccggccgtcg acaacgccgt
    15661 caagctcctg gccgactcgc cgctgcacgc actcgtgctc ggcttcacca gctcctcgta
    15721 cgtccttggc gttgacggcg agaacgcgct ctacgaacgc ctcgcccccg tcacccgcgg
    15781 catcccggtc accggcaccg cgagggcggc cgtcgccggc ttccgcgccc tgggcgccga
    15841 gcggatcgcg atcgtcaacc cgccctggtt cgacgacaag ctctccaccc agggccagga
    15901 gtacttcgag gcccagggct tcaccgtggt ccaccacgga cccgtcggcc tgccctccga
    15961 gcagaccgcc atcaccccgc agaacctgtc ggagtggatc cgcaccaccg tcgccgacgc
    16021 ccgccccgag gccatcctcg tcgccggcaa cggcatccgc gccgtcggca cgatccgcgg
    16081 cctcgaggac gagctgggct tccacgtcct gaccgccaac caggccgtcc tgtggcacgc
    16141 cctgcacctg gcgggcgccg ccgcggccgc cgcccgggtc accgactacg ggcgcctctt
    16201 ccgcgccgtc ccgaaggaag cgtgaccgga tgttacccgc cgacggctac gtcgccgtgt
    16261 tcaccacccc cgagggcgac gtctaccgca cccccctggt ctgctggcgc gccgacggac
    16321 cccacgtcta cggagtgacc ctccacaagg gcgggctgcg cagggccgag gaactccccg
    16381 gcttcacccg ctacgccgtc aagcccgact gctcctgcga cgcgaccgcg cccgccgtcc
    16441 cggcgcccgt cgacaggcag ctcgcgagcc ggtag
//
