BGC0001783: streptonigrin biosynthetic gene cluster from Streptomyces flocculus
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Location: 1 - 64,041 nt. (total: 64,041 nt).
This entry is originally from NCBI GenBank JQ414024.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001783
Short description streptonigrin biosynthetic gene cluster from Streptomyces flocculus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
JQ414024.1
via
Compounds
  • streptonigrin
Species Streptomyces flocculus [taxonomy]
References
Chemical products information
streptonigrin Evidence:
Copy SMILES
C25H22N4O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFW04547.1
 56 - 1792 (-) DNA binding protein
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    • AFW04548.1
    		 1985 - 3400 (+) prolyl-tRNA synthetase
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      • AFW04549.1
      • stnA
      		 3981 - 5108 (+) hydrolase
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        • AFW04550.1
        • stnB3
        		 5302 - 5580 (-) ferredoxin
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          • AFW04551.1
          • stnB2
          		 5580 - 6104 (-) aromatic ring dioxygenase b subunit
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            • AFW04552.1
            • stnB1
            		 6101 - 7582 (-) aromatic ring dioxygenase a subunit
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              • AFW04553.1
              • stnC
              		 7663 - 8355 (+) NAD(P)H dehydrogenase (quinone)
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                • AFW04554.1
                • stnD
                		 8393 - 9955 (+) 4-hydroxyphenylacetate-3-hydroxylase
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                  • AFW04555.1
                  • stnE
                  		 9963 - 10652 (+) DoxX family protein
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                    • AFW04556.1
                    • stnF1
                    		 10833 - 11663 (+) Leucine carboxyl methyltransferase
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                      • AFW04557.1
                      • stnG
                      		 11649 - 13259 (-) drug resistance transporter
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                        • AFW04558.1
                        • stnH1
                        		 13270 - 14292 (-) oxidoreductase
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                          • AFW04559.1
                          • stnI
                          		 14410 - 14952 (+) cyclase/dehydrase
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                            • AFW04560.1
                            • stnJ
                            		 14969 - 16537 (+) fatty-acid-CoA ligase FadD
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                              • AFW04561.1
                              • stnH2
                              		 16540 - 17751 (+) oxidoreductase
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                                • AFW04562.1
                                • stnK1
                                		 17748 - 19727 (+) hypothetical protein
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                                  • AFW04563.1
                                  • stnL
                                  		 19724 - 21142 (+) 3-carboxymuconate cycloisomerase PcaB
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                                    • AFW04564.1
                                    • stnM1
                                    		 21283 - 23172 (-) Anthranilate synthase,PhzE
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                                      • AFW04565.1
                                      • stnM2
                                      		 23169 - 23807 (-) Isochorismatase,PhzD
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                                        • AFW04566.1
                                        • stnN
                                        		 23820 - 24677 (-) 2,3-dihydroxybenzoate-2,3-dehydrogenase
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                                          • AFW04567.1
                                          • stnM3
                                          		 24665 - 26107 (-) PhzC, DAHP synthase
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                                            • AFW04568.1
                                            • stnO
                                            		 26749 - 28725 (+) ISXo8 transposase
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                                              • AFW04569.1
                                              • stnP1
                                              		 28738 - 29838 (+) FAD-dependent oxidoreductase
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                                                • AFW04570.1
                                                • stnG2
                                                		 29835 - 31526 (+) drug resistance transporter
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                                                  • AFW04571.1
                                                  • stnK2
                                                  		 31717 - 32676 (+) hypothetical protein
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                                                    • AFW04572.1
                                                    • stnP2
                                                    		 32669 - 33787 (+) FAD-dependent oxidoreductase
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                                                      • AFW04573.1
                                                      • stnQ1
                                                      		 33720 - 34970 (+) methyltransferase MppJ
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                                                        • AFW04574.1
                                                        • stnK3
                                                        		 34967 - 35362 (+) hypothetical protein
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                                                          • AFW04575.1
                                                          • stnR
                                                          		 35307 - 36512 (+) histidinol-phosphate aminotransferase
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                                                            • AFW04576.1
                                                            • stnG3
                                                            		 36550 - 37014 (+) Glyoxalase/bleomycin resistance protein
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                                                              • AFW04577.1
                                                              • stnF2
                                                              		 37203 - 38048 (-) Leucine carboxyl methyltransferase
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                                                                • AFW04578.1
                                                                • stnQ2
                                                                		 38115 - 38885 (-) catechol-O-methyltransferase
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                                                                  • AFW04579.1
                                                                  • stnS2
                                                                  		 39007 - 39993 (-) flavodoxin reductase Hmp
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                                                                    • AFW04580.1
                                                                    • stnT1
                                                                    		 40222 - 40845 (-) transcriptional regulator
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                                                                      • AFW04581.1
                                                                      • stnG4
                                                                      		 40939 - 42450 (-) drug resistance transporter
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                                                                        • AFW04582.1
                                                                        • stnK4
                                                                        		 42777 - 43202 (-) hypothetical protein
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                                                                          • AFW04583.1
                                                                          • stnQ3
                                                                          		 43633 - 44679 (+) methyltransferase
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                                                                            • AFW04584.1
                                                                            • stnS1
                                                                            		 44764 - 45996 (-) cytochrome P450
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                                                                              • AFW04585.1
                                                                              • stnF3
                                                                              		 46098 - 47162 (+) Leucine carboxyl methyltransferase
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                                                                                • AFW04586.1
                                                                                • stnF4
                                                                                		 47246 - 48121 (-) Leucine carboxyl methyltransferase
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                                                                                  • AFW04587.1
                                                                                  • stnU
                                                                                  		 48330 - 48515 (-) 4-oxalocrotonate tautomerase
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                                                                                    • AFW04588.1
                                                                                    • stnT2
                                                                                    		 48637 - 49659 (-) transcriptional regulator
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                                                                                      • AFW04589.1
                                                                                      • stnV
                                                                                      		 50080 - 51888 (+) asparagine synthase
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                                                                                        • AFW04590.1
                                                                                        • stnK5
                                                                                        		 51795 - 52931 (+) hypothetical protein
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                                                                                          • AFW04591.1
                                                                                          • stnW
                                                                                          		 52910 - 54040 (+) acyl-CoA dehydrogenase
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                                                                                            • AFW04592.1
                                                                                            • stnX
                                                                                            		 54004 - 55419 (+) dihydroorotase
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                                                                                              • AFW04593.1
                                                                                              • stnH3
                                                                                              		 55355 - 56566 (+) FAD-dependent oxidoreductase
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                                                                                                • AFW04594.1
                                                                                                • stnQ4
                                                                                                		 56625 - 57359 (+) methyltransferase
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                                                                                                  • AFW04595.1
                                                                                                  • stnT3
                                                                                                  		 57420 - 58187 (-) LuxR family transcriptional regulator
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                                                                                                    • AFW04596.1
                                                                                                    • stnT4
                                                                                                    		 58817 - 60097 (+) cyanate MFS transporter
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                                                                                                      • AFW04597.1
                                                                                                      		 60099 - 60776 (+) ArsR family transcriptional regulator
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                                                                                                        • AFW04598.1
                                                                                                        		 60787 - 62016 (+) monooxygenase
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                                                                                                          • AFW04599.1
                                                                                                          		 62085 - 62726 (+) methyltransferase
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                                                                                                            • AFW04600.1
                                                                                                            		 62739 - 63098 (-) hypothetical protein
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                                                                                                              • AFW04601.1
                                                                                                              		 63095 - 63934 (-) short chain dehydrogenase
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                                                                                                                Biosynthesis information
                                                                                                                Annotation changelog

                                                                                                                Entry version: 4

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2022-10-07
                                                                                                                Update chemical activity to schema version 2.11
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                Entry version: 3

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2022-09-15
                                                                                                                Updated bioactivity data
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                Entry version: 2

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2019-10-16
                                                                                                                Migrated from v1.4
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                2019-10-16
                                                                                                                Updated compound(s) information (NPAtlas curation)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                Entry version: 1

                                                                                                                Date
                                                                                                                Changes
                                                                                                                Submitters
                                                                                                                Reviewers
                                                                                                                2018-08-06
                                                                                                                Submitted
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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