BGC0001786 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001786 (Novosphingobium subterraneum (Sphingomonas subterranea))

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lassopeptide	1	22,396	High	subterisin	ribosomal:RiPP

BGC0001786 - Region 1 - lassopeptide

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Location: 1 - 22,396 nt. (total: 22,396 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lasso peptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,397
Label		BGC0001786

Tailoring functions

Hydrolases: hydrolase

NJ75_04141: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001786.3	1.00	ribosomal	subterisin	Novosphingobium subterraneum
BGC0000577.3	0.65	ribosomal	sphingonodin II	Sphingobium japonicum UT26S
BGC0000573.3	0.61	ribosomal	caulonodin I, caulonodin II	Caulobacter sp. K31
BGC0000576.3	0.56	ribosomal	rubrivinodin	Rubrivivax gelatinosus IL144
BGC0000580.3	0.52	ribosomal	xanthomonin II, xanthomonin I	Xanthomonas gardneri ATCC 19865
BGC0000574.3	0.50	ribosomal	caulosegnin I, caulosegnin II, caulosegnin III	Caulobacter segnis ATCC 21756
BGC0002334.3	0.38	other (other), ribosomal	heptyltyrazolone, nonyltyrazolone, undecyltyrazolone, (Z)-ω-6-undecenyltyrazolone	Pseudoalteromonas rubra
BGC0001151.5	0.34	other (non-nrp beta-lactam)	valclavam, (-)-2-(2-hydroxyethyl)clavam	Streptomyces antibioticus
BGC0002384.3	0.26	NRPS	lysocin E	Lysobacter sp.
BGC0002146.2	0.26	NRPS	FR901483	Cladobotryum sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001786.3	1.00	ribosomal	subterisin	Novosphingobium subterraneum
BGC0000577.3	0.65	ribosomal	sphingonodin II	Sphingobium japonicum UT26S
BGC0000573.3	0.61	ribosomal	caulonodin I, caulonodin II	Caulobacter sp. K31
BGC0000576.3	0.56	ribosomal	rubrivinodin	Rubrivivax gelatinosus IL144
BGC0000580.3	0.52	ribosomal	xanthomonin II, xanthomonin I	Xanthomonas gardneri ATCC 19865
BGC0000574.3	0.50	ribosomal	caulosegnin I, caulosegnin II, caulosegnin III	Caulobacter segnis ATCC 21756
BGC0002334.3	0.38	other (other), ribosomal	heptyltyrazolone, nonyltyrazolone, undecyltyrazolone, (Z)-ω-6-undecenyltyrazolone	Pseudoalteromonas rubra
BGC0001151.5	0.34	other (non-nrp beta-lactam)	valclavam, (-)-2-(2-hydroxyethyl)clavam	Streptomyces antibioticus
BGC0002384.3	0.26	NRPS	lysocin E	Lysobacter sp.
BGC0002146.2	0.26	NRPS	FR901483	Cladobotryum sp.

Similar known clusters from MIBiG 4.0

Lasso peptide predictions

Lassopeptide(s) for NJ75_04143

NJ75_04143

Leader:

MERTFDLVEDVEDLGTASIETL

Full core:

GPPGDRIEFGVLAQLPG

Putative macrolactam:

GPPGDRIE

NJ75_04143

Cleaved off residues:

LDRD

antiSMASH-DB 4.0 matches for NJ75_04143

100.0%

NZ_CP028347.1and 3 others:

NZ_CP063445.1 Lassopeptides: IM701_RS04335_lassopeptideNZ_JABAIC010000001.1 Lassopeptides: HGI46_RS00090_lassopeptideNZ_JABAID010000004.1 Lassopeptides: HGI47_RS08570_lassopeptide

Lassopeptides: C7W88_RS16880_lassopeptide

GPPGDRIEFGVLAQLPG

42.9%

NZ_JAJFET010000005.1:

Lassopeptides: LK533_RS10640_lassopeptide

GPPGDRIEFGVLAQ

G PG R EFGV+A+

GAPGSRTEFGVIAE

38.9%

NZ_CP095845.1:

Lassopeptides: MU856_RS10725_lassopeptide

GPPGDRIEFGVLAQL

GPP +IEF Q+

GPPDLQIEFSAFTQV

with 5 more sequence matches

38.1%

NZ_JABBGM010000014.1and 2 others:

NZ_JAPCZG010000009.1 Lassopeptides: OLX02_RS15855_lassopeptideNZ_JAROCY010000009.1 Lassopeptides: POM99_RS10785_lassopeptide

Lassopeptides: HHL27_RS19855_lassopeptide

GPPGDRIEFGVLAQ

G PG+++EFGV+A+

GAPGNQLEFGVIAR

38.1%

NZ_JABEOU010000012.1:

Lassopeptides: HKX06_RS03315_lassopeptide

GPPGDRIEFGVLAQ

G PG + E GV+AQ

GRPGFQTELGVIAQ

33.3%

NZ_CP017077.1:

Lassopeptides: BES08_RS34560_lassopeptide

GPPGDRIEF

GPPG IEF

GPPGPFIEF

27.3%

NZ_JARFNJ010000017.1:

Lassopeptides: PX554_RS23695_lassopeptide

GPPGDRIEF

GP GDR +F

GPSGDRDDF

19.4%

NZ_FOVP01000019.1:

Lanthipeptides: allorf_042174_042302_lanthipeptide

DRIEFGVLAQLPG

DR G Q+PG

DRFNLGSTHQMPG

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lasso peptides

Core peptide predictions

NJ75_04143 - Class II: Cleavage pHMM score: 1.00; RODEO score: 22; Monoisotopic mass: 1703.9 Da; Molecular weight: 1704.9 Da; Number of bridges: 0