MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AOT85892.1 ABC_transporter BGC0001788.3 ribosomal:RiPP 100.0 100.0 1306.0 0.0
AAB92603.1 ScnT BGC0000557.5 ribosomal:RiPP:Lanthipeptide 75.0 99.7 1008.0 0.0
ABK59359.1 MukT BGC0000534.3 ribosomal:RiPP:Lanthipeptide 73.0 99.7 996.0 0.0
ABI30230.1 McdT BGC0000526.5 ribosomal:RiPP:Lanthipeptide 72.0 99.7 960.0 0.0
ACX68645.1 putative_ABC_transporter BGC0000547.5 ribosomal:RiPP:Lanthipeptide 61.0 99.9 819.0 7e-294
BAC98761.2 NukT BGC0000539.5 ribosomal:RiPP:Lanthipeptide 39.0 100.1 476.0 4.11e-159
AAC72259.1 LctT BGC0000521.3 ribosomal:RiPP:Lanthipeptide 40.0 100.7 475.0 5.29e-159
CAC60277.1 RumT_protein BGC0000545.5 ribosomal:RiPP:Lanthipeptide 26.0 101.4 224.0 1.24e-63
AAA62651.1 BGC0000504.5 ribosomal:RiPP:Lanthipeptide 27.0 104.1 194.0 9.93e-53
AHF21240.1 CrnT BGC0000500.5 ribosomal:RiPP:Lanthipeptide 26.0 103.9 181.0 3.02e-48
AMQ71643.1 hypothetical_protein BGC0002663.2 ribosomal:RiPP 24.0 103.2 162.0 1.02e-41
AAB81307.1 ATP-dependent_translocator BGC0002579.2 ribosomal:RiPP 25.0 103.8 157.0 4.89e-40
ACR43772.1 ABC-transporter BGC0002577.2 ribosomal:RiPP 24.0 104.3 154.0 4.79e-39
BAR87968.1 ABC_transporter BGC0002674.2 ribosomal:RiPP 26.0 101.7 154.0 5.72e-39
AAZ76601.1 BhtT BGC0000497.3 ribosomal:RiPP:Lanthipeptide 25.0 104.5 151.0 6.6e-38
BAB78441.1 BGC0000555.3 ribosomal:RiPP:Lanthipeptide 25.0 104.3 150.0 1.35e-37
BAD72775.1 BGC0000552.3 ribosomal:RiPP:Lanthipeptide 26.0 104.8 150.0 1.59e-37
CZF83999.1 Toxin_RTX-I_translocation_ATP-binding_protein BGC0002382.3 ribosomal:RiPP 24.0 100.3 142.0 4.19e-35
ADP40527.1 ABC_transporter,_ATP-binding_protein BGC0003097.1 ribosomal:RiPP:Lanthipeptide 24.0 102.8 140.0 2.8e-34
AHJ59536.1 ABC_transporter_protein BGC0000502.5 ribosomal:RiPP:Lanthipeptide 24.0 103.9 138.0 1.1e-33
ADP40523.1 ABC_transporter,_ATP-binding_protein BGC0003097.1 ribosomal:RiPP:Lanthipeptide 25.0 103.3 134.0 3.49e-32
AAK27372.1 ABC_transporter BGC0000623.3 ribosomal:RiPP 25.0 104.6 130.0 3.26e-31
WP_027239422.1 NHLP_family_bacteriocin_export_ABC_transporter_peptidase/permease/ATPase_subunit BGC0002698.2 ribosomal:RiPP 24.0 104.6 127.0 5.83e-30
AXA91311.1 peptidase_domain-containing_ABC_transporter BGC0002044.2 NRPS:Type I 24.0 100.1 120.0 8.4e-28
QIZ86016.1 NHLP_family_bacteriocin_export_ABC_transporter BGC0002330.2 ribosomal:RiPP 24.0 108.4 119.0 1.84e-27
ABQ84449.1 salivaricin_ABC-transporter BGC0000624.3 ribosomal:RiPP 23.0 103.9 113.0 1.57e-25
WP_010071703.1 peptidase_domain-containing_ABC_transporter BGC0000554.4 ribosomal:RiPP:Lanthipeptide 23.0 95.7 106.0 1.85e-23
EMC15128.1 ABC_transporter,_ATP-binding_and_permease_protein BGC0000530.5 ribosomal:RiPP:Lanthipeptide 36.0 28.4 105.0 2.34e-23
RPK60839.1 Lactococcin-G-processing_and_transport_ATP-binding_protein_LagD BGC0003050.1 ribosomal:RiPP:Lanthipeptide 23.0 96.1 104.0 9.93e-23
AAD56148.1 MutT BGC0000533.3 ribosomal:RiPP:Lanthipeptide 33.0 31.7 103.0 1.3e-22
EKJ70675.1 hypothetical_protein BGC0002188.3 NRPS:Type I+PKS 31.0 33.8 102.0 8.58e-22
QKI29071.1 ABC_transporter_ATP-binding_protein BGC0002130.3 ribosomal:RiPP:Lanthipeptide 27.0 36.4 99.0 2.67e-21
AFY23032.1 TamA BGC0000274.5 PKS:Type II 29.0 41.7 99.0 3.83e-21
CAD15510.1 probable_composite_atp-binding_transmembrane_abc_transporter_protein BGC0001014.5 NRPS:Type I+PKS:Type I 33.0 31.2 98.0 9.25e-21
CAP20371.1 ABC_transporter_ATP-binding_membrane_protein BGC0000347.5 NRPS:Type I 26.0 70.1 96.0 3.36e-20
QGN18865.1 nsjT_ABC_transporter_ATP-binding_protein BGC0002323.2 ribosomal:RiPP:Lanthipeptide 33.0 31.2 96.0 3.4e-20
QSE03592.1 Lcm8 BGC0002333.3 PKS 29.0 32.8 96.0 4.41e-20
OEI76260.1 thiol_reductant_ABC_exporter_subunit_CydC BGC0002977.1 NRPS:Type I+PKS:Type I 30.0 32.3 95.0 5.79e-20
QBF29318.1 ABC_transporter_ATP-binding_protein BGC0002294.3 other:other 27.0 39.7 92.0 4.41e-19
ABO65651.1 Putative_SpaT BGC0000515.4 ribosomal:RiPP:Lanthipeptide 32.0 34.1 91.0 1.41e-18
AAB91587.1 SpaT BGC0000559.4 ribosomal:RiPP:Lanthipeptide 24.0 53.9 91.0 1.88e-18
QPP19365.1 Pen6 BGC0002501.3 other:other 29.0 33.9 90.0 3.07e-18
QWT72283.1 ABC_transporter_ATP-binding_protein BGC0002430.3 NRPS:Type I+saccharide 26.0 40.7 90.0 3.49e-18
QQZ01651.1 ABC_transporter BGC0002497.3 other:other 27.0 34.6 90.0 3.97e-18
AFW17836.1 PaeT BGC0000541.5 ribosomal:RiPP:Lanthipeptide 31.0 33.3 89.0 4.47e-18
XP_011392729.1 ABC_transporter BGC0001281.3 PKS 33.0 33.9 90.0 4.53e-18
ADM69295.1 paenilan_transporter BGC0001727.3 ribosomal:RiPP 29.0 35.1 89.0 4.55e-18
AVX51096.1 nysH BGC0001709.5 PKS 22.0 42.5 89.0 5.34e-18
ABS50188.1 putative_ABC_transporter_permease/ATP-binding_protein BGC0000410.5 NRPS:Type I 31.0 34.8 89.0 5.53e-18
ALR96371.1 lantibiotic_ABC_transporter BGC0001289.5 ribosomal:RiPP 26.0 34.9 88.0 1.03e-17
MBX4267533.1 ABC_transporter_ATP-binding_protein/permease BGC0002668.2 ribosomal:RiPP 25.0 53.8 88.0 1.29e-17
OEI74473.1 ABC_transporter_ATP-binding_protein BGC0002977.1 NRPS:Type I+PKS:Type I 30.0 31.2 83.0 1.31e-17
BAE56595.1 BGC0001123.5 NRPS:Type I 27.0 34.5 88.0 1.77e-17
CUI65312.1 Putative_multidrug_export_ATP-binding/permease_protein_SAV1866 BGC0003015.1 ribosomal:RiPP:Lasso peptide 32.0 35.7 87.0 2.16e-17
WP_051767685.1 ABC_transporter_ATP-binding_protein BGC0002009.4 PKS 23.0 44.3 87.0 2.2e-17
OJF16286.1 AceT1 BGC0001491.3 PKS 27.0 37.1 86.0 3.72e-17
WP_027239423.1 ATP-binding_cassette_domain-containing_protein BGC0002698.2 ribosomal:RiPP 30.0 31.4 86.0 5.91e-17
AAF71764.1 NysH BGC0000115.5 PKS:Type I+saccharide:hybrid/tailoring 23.0 44.1 86.0 6.64e-17
ESU07740.1 hypothetical_protein BGC0003072.1 NRPS:Type I 26.0 35.1 86.0 7.2e-17
AKU24610.1 ABC_transporter_ATP-binding_protein BGC0002687.2 PKS+NRPS:Type I 28.0 30.6 85.0 9.12e-17
AHZ61877.1 Lom43 BGC0000240.5 PKS:Type II+saccharide:hybrid/tailoring 26.0 39.9 85.0 1.18e-16
MBE3200463.1 ABC_transporter_ATP-binding_protein BGC0002409.3 NRPS:Type I 26.0 34.1 85.0 1.22e-16
AEK64492.1 EtnT BGC0000506.4 ribosomal:RiPP:Lanthipeptide 23.0 53.9 85.0 1.24e-16
AAM80540.1 StaU BGC0000290.5 NRPS:Type I 26.0 41.9 85.0 1.32e-16
AEX55160.1 putative_ABC_transporter_SlvT BGC0000549.3 ribosomal:RiPP:Lanthipeptide 32.0 31.7 84.0 1.64e-16
CAC20924.1 PimA_protein BGC0000125.5 PKS 26.0 43.2 84.0 2.12e-16
EFV97027.1 ABC_transporter,_ATP-binding_protein BGC0003095.1 ribosomal:RiPP:Lanthipeptide 29.0 34.5 84.0 2.12e-16
EYT83451.1 ABC_transporter_ATP-binding_protein BGC0001213.5 PKS 28.0 35.4 84.0 2.83e-16
AQT01390.1 SgnA BGC0001690.5 PKS 30.0 31.9 84.0 2.83e-16
AAL15565.1 putative_SpaT BGC0000511.5 ribosomal:RiPP:Lanthipeptide 23.0 53.9 84.0 2.87e-16
CCA53801.1 Transport_ATP-binding_protein_CydC BGC0001801.5 NRPS:Type I 27.0 36.1 83.0 3.78e-16
AOT85870.1 ABC_transporter BGC0001789.3 ribosomal:RiPP 29.0 34.5 83.0 4.89e-16
ABV83219.1 CppH BGC0000116.5 PKS 23.0 42.5 82.0 6.21e-16
ABA00880.1 NsuT BGC0000537.3 ribosomal:RiPP:Lanthipeptide 27.0 34.3 82.0 6.41e-16
AAK01464.1 ABC_transporter BGC0000412.5 NRPS:Type I 29.0 32.9 82.0 1.05e-15
BAB08163.1 SrtT BGC0000556.5 ribosomal:RiPP:Lanthipeptide 27.0 39.9 81.0 1.47e-15
QIZ24092.1 putative_ABC_transporter BGC0002540.3 PKS 28.0 31.9 81.0 2.18e-15
BAG71481.1 ATP-binding_cassette_transporter BGC0000536.3 ribosomal:RiPP:Lanthipeptide 26.0 40.3 80.0 4.52e-15
WOA03500.1 FscG BGC0002987.1 PKS:Type I 30.0 27.2 80.0 5.64e-15
ALE27500.1 ABC_transporter BGC0001292.5 other:other 26.0 35.7 79.0 6.03e-15
NII05602.1 ABC_transporter_ATP-binding_protein BGC0003005.1 NRPS:Type I 30.0 31.6 79.0 7.67e-15
ABP54659.1 ABC_transporter_related BGC0000241.5 PKS:Type II+saccharide:hybrid/tailoring 25.0 39.9 79.0 7.73e-15
QYA95652.1 ABC_transporter_ATP-binding_protein/permease BGC0002676.2 NRPS:Type I 26.0 37.5 79.0 1.04e-14
CAC17506.1 putative_ABC_transporter_ATP-binding_protein BGC0000324.5 NRPS:Type I 29.0 33.2 79.0 1.06e-14
QUQ72367.1 ABC_transporter BGC0002349.3 PKS:Type I 26.0 33.2 78.0 1.4e-14
ABW70811.1 PchH BGC0002475.3 NRPS:Type I 28.0 34.2 78.0 1.76e-14
CAI47638.1 putative_ABC-type_aminoglycoside_exporter BGC0000692.5 saccharide 23.0 37.8 78.0 1.82e-14
BAI23327.1 putative_ABC-transporter BGC0000949.5 NRPS:Type I 26.0 35.1 77.0 2.43e-14
ARD70884.1 ABC_transporter BGC0001693.3 PKS 26.0 32.5 77.0 3.1e-14
EME52991.1 ABC_transporter BGC0001460.5 NRPS:Type I 27.0 32.6 77.0 3.43e-14
AQZ71346.1 ABC_transporter BGC0001635.4 NRPS:Type I+PKS 28.0 30.6 77.0 4.43e-14
CAD91219.1 putative_ABC_transporter,_Dbv24 BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 28.0 28.6 77.0 4.52e-14
QYC40286.1 Multidrug_export_ATP-binding/permease_protein BGC0002344.2 NRPS:Type I 28.0 28.6 77.0 4.52e-14
CAP20369.1 putative_ABC_transporter_ATP-binding_component BGC0000347.5 NRPS:Type I 29.0 29.9 76.0 6.62e-14
AHH99931.1 ABC_transporter_protein BGC0000002.5 PKS 26.0 33.2 76.0 7.28e-14
AZM50109.1 ABC_transporter BGC0002702.3 NRPS:Type I 27.0 32.5 76.0 8.48e-14
CAA79469.1 NisT_protein BGC0000538.3 ribosomal:RiPP:Lanthipeptide 28.0 33.9 76.0 9.64e-14
MCC5036774.1 ABC_transporter_ATP-binding_protein/permease BGC0002638.3 NRPS:Type I 24.0 42.9 76.0 1.04e-13
CAA11793.1 PCZA363.2 BGC0000322.3 NRPS:Type I 28.0 32.6 76.0 1.04e-13
ctg1_orf1267 BGC0001752.4 NRPS:Type I 30.0 27.4 76.0 1.07e-13
OKA09422.1 ABC_transporter BGC0001459.5 NRPS:Type I 27.0 32.6 75.0 1.37e-13
AZM57021.1 ABC_transporter BGC0002314.3 NRPS:Type I 26.0 32.0 75.0 1.49e-13
ALK21572.1 multidrug_ABC_transporter_permease BGC0002678.2 NRPS:Type I 31.0 28.6 75.0 1.6e-13
ADJ56354.1 NisT BGC0000535.4 ribosomal:RiPP:Lanthipeptide 28.0 33.9 74.0 2.22e-13
AGF91752.1 ABC_transporter BGC0003168.1 NRPS:Type I+saccharide 27.0 32.8 74.0 2.42e-13
CAF32376.1 putative_ABC_transporter,_ATP-binding_protein BGC0000712.5 saccharide 27.0 31.9 74.0 2.95e-13
CAG25756.1 putative_ABC_transporter_ATP-binding_protein BGC0000311.6 saccharide+NRPS:Type I 28.0 28.4 74.0 3.15e-13
ABD65953.1 ABC_transporter BGC0000341.5 NRPS:Type I 28.0 28.6 74.0 3.15e-13
OLZ52458.1 ABC_transporter BGC0001462.5 NRPS:Type I 27.0 32.6 74.0 3.16e-13
AGS77319.1 ABC_transporter BGC0001178.5 NRPS:Type I 27.0 30.9 74.0 4.21e-13
BCB17010.1 putative_ABC_transporter_ATP-binding_protein BGC0002523.2 NRPS:Type I 27.0 31.7 74.0 4.28e-13
AEI58864.1 ABC_transporter BGC0000455.6 saccharide+NRPS:Type I 27.0 32.6 74.0 4.46e-13
WEV24176.1 ABC_transporter_ATP-binding_protein BGC0002994.1 NRPS:Type I 28.0 27.4 73.0 6.51e-13
AIE77056.1 ABC-transporter BGC0000418.5 NRPS:Type I 29.0 28.4 72.0 9.16e-13
CAD97586.1 ATP_binding_protein BGC0000488.4 ribosomal:unmodified 25.0 33.9 69.0 1.15e-12
AGI92083.1 ABC_efflux_pump BGC0002115.3 ribosomal:unmodified 27.0 31.6 72.0 1.16e-12
AYA22337.1 Tri BGC0001955.4 saccharide+NRPS:Type I 27.0 32.6 72.0 1.63e-12
OLZ50884.1 ABC_transporter BGC0001461.5 NRPS:Type I 27.0 32.6 72.0 1.65e-12
UUG66849.1 Plx4 BGC0002939.1 NRPS:Type I 27.0 31.3 68.0 2.13e-12
ABL74935.1 TlmT BGC0001048.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 24.0 41.3 71.0 2.69e-12
AIG79244.1 Conserved_putative_membrane_protein BGC0000419.5 NRPS:Type I+saccharide 28.0 28.4 71.0 3.8e-12
AHW56375.1 ABC_transporter BGC0002983.1 NRPS:Type III+saccharide 25.0 36.5 70.0 4.91e-12
BAL15761.1 ABC_transporter BGC0003155.1 NRPS:Type III+saccharide 25.0 36.5 70.0 4.91e-12
CAE53357.1 ABC_transporter BGC0000440.5 NRPS:Type I 27.0 28.6 70.0 5e-12
CAG15016.1 ABC_transporter BGC0000441.4 NRPS:Type I 27.0 28.6 70.0 5e-12
ctg1_orf169 BGC0001638.4 ribosomal:RiPP 26.0 37.5 70.0 5.62e-12
CEG06583.1 ABC_transporter BGC0001928.2 other:other 26.0 33.5 68.0 5.82e-12
BAJ19058.1 putative_ABC_transporter BGC0000288.5 NRPS:Type I 27.0 30.6 70.0 6.8e-12
MCC5036782.1 ABC_transporter_ATP-binding_protein/permease BGC0002638.3 NRPS:Type I 23.0 43.3 69.0 1.15e-11
CBF87872.1 ABC_multidrug_transporter_(Eurofung) BGC0001699.4 NRPS:Type I 27.0 29.9 69.0 1.5e-11
MBE3202945.1 ABC_transporter_ATP-binding_protein BGC0002410.3 NRPS:Type I 28.0 29.4 68.0 1.87e-11
ALK27913.1 putative_ABC_transporter BGC0001233.5 NRPS:Type I 25.0 32.0 68.0 2.07e-11
RSO11557.1 ABC_transporter BGC0002637.3 NRPS:Type I 28.0 28.6 68.0 2.07e-11
ATW47206.1 multidrug_ABC_transporter_permease BGC0002466.3 NRPS:Type I 26.0 32.0 67.0 5.62e-11
QWF78559.1 Multidrug_resistance_ABC_transporter_ATP-binding/permease_protein_BmrA BGC0002142.2 PKS 23.0 39.3 66.0 7.63e-11
OUH62398.1 hypothetical_protein BGC0001639.3 ribosomal:RiPP:Lasso peptide 25.0 31.9 66.0 9.68e-11
CBG75489.1 putative_ABC-transport_system_ATP-binding_component BGC0000423.5 NRPS:Type I 27.0 29.7 66.0 1.34e-10
OEI72904.1 zinc_ABC_transporter_ATP-binding_protein BGC0002977.1 NRPS:Type I+PKS:Type I 24.0 30.4 62.0 2.64e-10
CAK15812.1 macrolide_ABC_efflux_protein_MacB BGC0000344.5 NRPS:Type I 27.0 29.9 63.0 7.33e-10
QFU91020.1 Lipid_A_export_ATP-binding/permease_protein_MsbA BGC0002064.2 ribosomal:RiPP 27.0 29.0 62.0 1.51e-09
UUG47332.1 ABC_transporter_ATP-binding_protein BGC0002932.1 PKS:Type II aromatic 27.0 25.7 59.0 2.81e-09
AEI40461.1 ABC_transporter_ATP_binding_protein BGC0002488.3 other:other 25.0 34.6 59.0 3.2e-09
CAH10182.1 ChaT3_protein BGC0000207.5 PKS 24.0 31.2 59.0 4.47e-09
OEI76332.1 amino_acid_ABC_transporter_ATP-binding_protein BGC0002977.1 NRPS:Type I+PKS:Type I 28.0 35.4 58.0 6.52e-09
BAB58626.1 oligopeptide_transporter_putative_ATPase_domain BGC0002487.3 other:other 24.0 32.5 58.0 8.2e-09
OAQ83754.1 ABC_multidrug_transporter BGC0001358.4 NRPS:Type I+PKS 25.0 28.4 60.0 8.7e-09
MBE3200464.1 ABC_transporter_ATP-binding_protein BGC0002409.3 NRPS:Type I 27.0 27.4 59.0 1.05e-08
AEI40462.1 ABC_transporter_ATP_binding_protein BGC0002488.3 other:other 23.0 33.5 57.0 1.15e-08
APZ78819.1 ABC_transporter_ATP-binding_protein BGC0001429.4 NRPS:Type I+PKS:Iterative type I 27.0 34.2 57.0 1.31e-08
QMN69936.1 PsoE BGC0002521.3 NRPS:Type I 26.0 29.6 59.0 1.52e-08
BAC87909.1 probable_ABC_transporter BGC0000294.5 NRPS:Type I 26.0 29.6 59.0 1.74e-08
AAF67272.1 CexA BGC0000735.3 saccharide 27.0 29.9 56.0 1.96e-08
APZ78843.1 ABC_transporter_ATP-binding_protein BGC0001431.4 NRPS:Type I+PKS:Iterative type I 26.0 30.7 55.0 5.78e-08
QTC09991.1 ABC_transporter_ATP-binding_protein BGC0002372.3 PKS+terpene+other:other 26.0 33.9 55.0 6.41e-08
BAG22744.1 putative_ABC-type_multidrug_transport_system_ATPase_and_permease_component BGC0000724.5 saccharide 25.0 30.0 57.0 7.35e-08
CQR60040.1 Uncharacterized_ABC_transporter_ATP-binding_protein_YfiC BGC0002289.2 ribosomal:RiPP:Lasso peptide 24.0 28.7 57.0 7.37e-08
OEI75893.1 cell_division_ATP-binding_protein_FtsE BGC0002977.1 NRPS:Type I+PKS:Type I 25.0 30.0 54.0 9.87e-08
QQZ01605.1 ABC_transporter BGC0002498.3 other:other 24.0 29.1 55.0 1.32e-07
CAM03501.1 putative_ABC_transporter BGC0000513.3 ribosomal:RiPP:Lanthipeptide 24.0 28.0 55.0 2.83e-07
ABC39037.1 cyclic_peptide_ABC_transporter,_ATP-binding_protein BGC0000386.5 NRPS:Type I 25.0 29.9 54.0 3.76e-07
BCB17025.1 putative_ABC_transporter_protein BGC0002523.2 NRPS:Type I 25.0 25.8 52.0 8.53e-07
CCG06125.1 putative_oligopeptide_ABC_transporter,_ATPase BGC0001543.3 PKS 25.0 28.3 52.0 1.23e-06
AGK15450.1 ABC_transporter,_transmembrane_region,_ATP_binding_component BGC0002529.3 NRPS:Type I 22.0 37.0 52.0 1.48e-06
NAO96331.1 multidrug_ABC_transporter_permease/ATP-binding_protein BGC0002117.3 NRPS:Type I 27.0 25.1 52.0 1.48e-06
BAH43758.1 putative_truncated_ABC_transporter_ATP-binding_protein BGC0000452.5 NRPS:Type I 28.0 25.4 50.0 1.58e-06
QEO75092.1 ABC_transporter_ATP-binding_protein BGC0002079.2 NRPS:Type I 27.0 28.4 50.0 2.13e-06
ABI87094.1 cyclic_peptide_transporter BGC0002531.3 NRPS:Type I 23.0 28.6 52.0 2.64e-06
CAR51993.1 ornibactin_biosynthesis_ABC_transport_protein BGC0002569.3 NRPS:Type I 23.0 28.6 52.0 2.64e-06
AAX98195.1 ABC_transporter BGC0000052.5 PKS 24.0 28.4 51.0 2.85e-06