Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001807.1:
Cluster 1NRP / Polyketide198792

BGC0001807, totopensamide biosynthetic gene cluster from Streptomyces pactum. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: totopensamide

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Modular Type I

Gene cluster description

totopensamide (BGC0001807). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank MG012231. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Chen R et al. (2017) Genome Mining and Activation of a Silent PKS/NRPS Gene Cluster Direct the Production of Totopotensamides. Org Lett 19(20):5697-5700. doi: 10.1021/acs.orglett.7b02878. Epub