Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001812.1:
Cluster 1Polyketide173895

BGC0001812, tylactone biosynthetic gene cluster from Micromonospora chalcea. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: tylactone
SMILES string: Copy to clipboard

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:

Gene cluster description

tylactone (BGC0001812). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank MF033535. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Lowell AN et al. (2017) Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C-H Functionalization. J Am Chem Soc 139(23):7913-7920. doi: 10.1021/jacs.7b02875. Epub