BGC0001822: vioprolide A biosynthetic gene cluster from Cystobacter sp.
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Location: 1 - 44,663 nt. (total: 44,663 nt).
This entry is originally from NCBI GenBank MH108942.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001822
Short description vioprolide A biosynthetic gene cluster from Cystobacter sp.
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: MH108942.1
Compounds
  • vioprolide A
  • vioprolide B
  • vioprolide C
  • vioprolide D
Species Cystobacter sp. [taxonomy]
References
Chemical products information
vioprolide A
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C40H62N8O11S1
Chemical database entries
PubCHEM
vioprolide B
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C40H62N8O11S1
Chemical database entries
PubCHEM
vioprolide C
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C39H60N8O11S1
Chemical database entries
PubCHEM
vioprolide D
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C39H60N8O11S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWI62625.1
  • vioL
 185 - 1321 (+) lysine cyclodeaminase
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  • AWI62626.1
  • vioA
 1321 - 16062 (+) nonribosomal peptide synthetase
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  • AWI62627.1
  • vioB
 16083 - 22562 (+) nonribosomal peptide synthetase
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  • AWI62628.1
  • vioC
 22559 - 32521 (+) nonribosomal peptide synthetase
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  • AWI62629.1
  • vioD
 32518 - 37905 (+) nonribosomal peptide synthetase
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  • AWI62630.1
  • vioE
 37902 - 39704 (+) hypothetical protein
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  • AWI62631.1
  • vioF
 39719 - 41050 (+) hypothetical protein
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  • AWI62632.1
  • vioG
 41130 - 42782 (+) hypothetical protein
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  • AWI62633.1
  • vioH
 42779 - 43492 (+) hypothetical protein
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  • AWI62634.1
  • vioI
 43564 - 43854 (+) hypothetical protein
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  • AWI62635.1
  • vioJ
 43892 - 44182 (+) hypothetical protein
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  • AWI62636.1
  • vioK
 44290 - 44502 (+) MbtH-like domain-containing protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
vioA
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
vioB
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
vioC
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: pipecolic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
vioD
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Fetched compound information from PubChem
  • Added NRP substrate specificities
Detailed domain annotation
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