BGC0001838: WLIP biosynthetic gene cluster from Pseudomonas putida
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Location: 1 - 31,000 nt. (total: 31,000 nt).
This entry is originally from NCBI GenBank JN982333.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001838
Short description WLIP biosynthetic gene cluster from Pseudomonas putida
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "Wlip gene cluster"
Biosynthetic class(es)
  • NRPS (Type I)
Loci
JN982333.1
via Enzymatic assays
Compounds
  • WLIP
Species Pseudomonas putida [taxonomy]
References
Chemical products information
WLIP Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFJ23822.1
 119 - 1234 (-) sigma-54-dependent transcriptional regulator
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    • AFJ23823.1
    		 1245 - 2432 (-) acyl-COA dehydrogenase
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      • AFJ23824.1
      		 2442 - 3002 (-) FMN reductase
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        • AFJ23825.1
        • wlpB
        		 3354 - 16256 (+) WLIP synthetase B
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          • AFJ23826.1
          • wlpC
          		 16253 - 27655 (+) WLIP synthetase C
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            • AFJ23827.1
            • wlpD
            		 27792 - 28949 (+) MacA-like protein
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              • AFJ23828.1
              • wlpE
              		 28946 - 30958 (+) MacB-like ABC transporter protein
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                Biosynthesis information

                Biosynthetic modules

                Name
                Unk01
                Type
                nrps-type1
                Genes
                wlpB
                Substrates
                threonine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk02
                Type
                nrps-type1
                Genes
                wlpB
                Substrates
                valine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk03
                Type
                nrps-type1
                Genes
                wlpB
                Substrates
                leucine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk04
                Type
                nrps-type1
                Genes
                wlpB
                Substrates
                serine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk05
                Type
                nrps-type1
                Genes
                wlpC
                Substrates
                leucine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk06
                Type
                nrps-type1
                Genes
                wlpC
                Substrates
                serine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk07
                Type
                nrps-type1
                Genes
                wlpC
                Substrates
                isoleucine (evidence: )
                Integrated Monomers
                Domains
                adenylation
                Annotation changelog

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                2022-10-07
                Update chemical activity to schema version 2.11
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                2022-09-15
                Updated bioactivity data
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                2022-09-15
                Added NRP substrate specificities
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                2019-10-16
                Submitted
                • (ID: 7UL6TWXRIUBGJOWL4IAXMLCC)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
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