LOCUS       BGC0001841             14340 bp    DNA     linear   BCT 28-NOV-2019
DEFINITION  TPA_exp: Amycolatopsis jejuensis detoxin P1,P2,P3 biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0001841
VERSION     BGC0001841
KEYWORDS    .
SOURCE      Amycolatopsis jejuensis
  ORGANISM  Amycolatopsis jejuensis
            Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
            Amycolatopsis.
COMMENT     THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entry JNYZ01000002.1
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 04:53:17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14340
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..14340
                     /culture_collection="NRRL:B-24427"
                     /db_xref="taxon:330084"
                     /mol_type="genomic DNA"
                     /organism="Amycolatopsis jejuensis"
                     /strain="NRRL B-24427"
                     /type_material="type strain of Amycolatopsis jejuensis"
     misc_feature    1..14340
                     /note="detoxin P1,P2,P3 biosynthetic gene cluster"
     protocluster    1..14340
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[6:12152]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7..12152
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..14340
                     /SMILES="NC(C(C)CC)C(=O)N1C(CCC1)C(=O)NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..14340
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001841"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..14340
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            7..3789
                     /gene="detF"
     CDS             7..3789
                     /NRPS_PKS="Domain: Condensation_LCL (3-298). E-value:
                     6.5e-97. Score: 315.9. Matches aSDomain:
                     nrpspksdomains_detF_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (462-845). E-value:
                     1.2e-103. Score: 338.7. Matches aSDomain:
                     nrpspksdomains_detF_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (951-1020). E-value: 3.2e-19. Score:
                     60.8. Matches aSDomain: nrpspksdomains_detF_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1039-1256). E-value:
                     5.4e-30. Score: 97.3. Matches aSDomain:
                     nrpspksdomains_detF_Thioesterase.1"
                     /codon_start=1
                     /gene="detF"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     363.8; E-value: 2e-110)"
                     /gene_kind="biosynthetic"
                     /product="peptide synthetase"
                     /protein_id="DAC80524.1"
                     /sec_met_domain="Condensation (E-value: 1e-78, bitscore:
                     252.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-114, bitscore:
                     369.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-13, bitscore:
                     39.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSAPLSSGQQRLWTVSQLTEAGSAYNETMAFTLRGPLDRAALR
                     RALDALAERHETLRTRFAVEDGQPVQIVLDETGFPCTVTDVTGQPEDKAALRRTEPFEP
                     FDLASAPPARARLLIDGPEHHILLITVHHIVFDGWSRTVLLRELGVLYTAELRGDLADL
                     PETRPYREYARAQQDWLAGPAPQPHETYWGDRLDGVPAVLDLPADRPRPARQDYRGARV
                     RVSLGPHLTAAVKKLAREHGVTPYSAVLTCWSMLLSRLSGQDDIVVGVPTANRGGGGEY
                     PATIGFFVNTLAVRADLGGGVTGAVLLKQVRAALRGAIDHVGLPFERVVELVNPPRSPA
                     HTPLFQTMVAWVPTVHDLLELPGVAAEPLEVEHAPAKFDLALGMADEDGDITGHLDYAV
                     ALFDHATAQRYARYFVRLLEQLVARPDAEATSYELLDEAERREILAWSAGPRPNRRPGG
                     LVERFTAHADAAPDAPALVCDGRTSTYGELDQRTTRLANALRARGVGPGEVVAIHSERS
                     TELVVAVLGVLKAGAAYLPLDPAQPPARREAMIEDARPALVLRDDPDSIAALAAEGDPK
                     RRLVPAGPGETAYVIYTSGSTGRPKGVAVTHHSVLALFDQWLDRFGATPGEATSAWSGI
                     GFDASVHELLLPLTTGAVLHVVPEDVRADPAALLAWLREHQVVQAFLPPSYVRWIDEDP
                     ARAAGLALRHVLTGVEPLPEAALARFAAAVPGLRICFGYGPTEATLYATAHFDPQPVDR
                     PAPIGRPLPGSRMYLLDERLRPVPPGIAGEVFLAGDCLARGYLHRPGLTAERFVPDPFA
                     PGERMYRTGDLARWLPSGEAEYAGRRDDQIKLRGFRIEPGEVTAALLAVPGVREAAVLV
                     DRAGEPKLVAGVAGGGRTLHEWRAALADRLPDYMIPSVFAEFDRLPLNPSGKLDRDAVL
                     AQARASTAVNTVNTAAPRDHVELALHRIWRNLLLHPSIGVSDDFFDVGGTSISAIKLAH
                     TIGTEFGRELPIRDVILHPTIEAQAALLRADEPASAGGSLIEFRRGTGRARVVCVHPAG
                     GTAFCYLPLSAALPEDAGVVGIQSPGLGPGEEPLPSVEAMAEEYLRLVAPQPGEVLVLC
                     GLSYGGLVAYEMGRRLAKRHPRVSVVLLDTAGTDDPAARAAIGPVPAAEFREKLVRFNG
                     MYPGIEDAQIERYHRTYNHNRHTAREHDPGESAARVVFVQATGEDTIPGGDEFWRRRVL
                     GEFEVVPVGCGHWDLLESAALPRVAELITAELADR"
     aSDomain        16..900
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.50E-97"
                     /label="detF_Condensation_LCL.1"
                     /locus_tag="detF"
                     /protein_end="298"
                     /protein_start="3"
                     /score="315.9"
                     /tool="antismash"
                     /translation="SAPLSSGQQRLWTVSQLTEAGSAYNETMAFTLRGPLDRAALRRAL
                     DALAERHETLRTRFAVEDGQPVQIVLDETGFPCTVTDVTGQPEDKAALRRTEPFEPFDL
                     ASAPPARARLLIDGPEHHILLITVHHIVFDGWSRTVLLRELGVLYTAELRGDLADLPET
                     RPYREYARAQQDWLAGPAPQPHETYWGDRLDGVPAVLDLPADRPRPARQDYRGARVRVS
                     LGPHLTAAVKKLAREHGVTPYSAVLTCWSMLLSRLSGQDDIVVGVPTANRGGGGEYPAT
                     IGFFVNTLAVRADL"
     aSModule        16..3774
                     /complete
                     /domains="nrpspksdomains_detF_Condensation_LCL.1"
                     /domains="nrpspksdomains_detF_AMP-binding.1"
                     /domains="nrpspksdomains_detF_PCP.1"
                     /domains="nrpspksdomains_detF_Thioesterase.1"
                     /final_module
                     /locus_tags="detF"
                     /monomer_pairings="val -> val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       79..195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0001"
                     /evalue="9.70E-20"
                     /label="C2_LCL_024-062"
                     /locus_tag="detF"
                     /protein_end="63"
                     /protein_start="24"
                     /score="63.0"
                     /tool="antismash"
                     /translation="SAYNETMAFTLRGPLDRAALRRALDALAERHETLRTRFA"
     CDS_motif       397..462
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0002"
                     /evalue="1.60E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="detF"
                     /protein_end="152"
                     /protein_start="130"
                     /score="33.4"
                     /tool="antismash"
                     /translation="VHHIVFDGWSRTVLLRELGVLY"
     CDS_motif       799..891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0003"
                     /evalue="2.20E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="detF"
                     /protein_end="295"
                     /protein_start="264"
                     /score="36.2"
                     /tool="antismash"
                     /translation="DIVVGVPTANRGGGGEYPATIGFFVNTLAVR"
     CDS_motif       940..1059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0004"
                     /evalue="3.50E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="detF"
                     /protein_end="351"
                     /protein_start="311"
                     /score="54.7"
                     /tool="antismash"
                     /translation="RAALRGAIDHVGLPFERVVELVNPPRSPAHTPLFQTMVAW"
     aSDomain        1393..2541
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_AMP-binding.1"
                     /evalue="1.20E-103"
                     /label="detF_AMP-binding.1"
                     /locus_tag="detF"
                     /protein_end="845"
                     /protein_start="462"
                     /score="338.7"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="FTAHADAAPDAPALVCDGRTSTYGELDQRTTRLANALRARGVGPG
                     EVVAIHSERSTELVVAVLGVLKAGAAYLPLDPAQPPARREAMIEDARPALVLRDDPDSI
                     AALAAEGDPKRRLVPAGPGETAYVIYTSGSTGRPKGVAVTHHSVLALFDQWLDRFGATP
                     GEATSAWSGIGFDASVHELLLPLTTGAVLHVVPEDVRADPAALLAWLREHQVVQAFLPP
                     SYVRWIDEDPARAAGLALRHVLTGVEPLPEAALARFAAAVPGLRICFGYGPTEATLYAT
                     AHFDPQPVDRPAPIGRPLPGSRMYLLDERLRPVPPGIAGEVFLAGDCLARGYLHRPGLT
                     AERFVPDPFAPGERMYRTGDLARWLPSGEAEYAGRRDDQIKLR"
     CDS_motif       1579..1620
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0005"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="detF"
                     /protein_end="538"
                     /protein_start="524"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LGVLKAGAAYLPLD"
     CDS_motif       1768..1827
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0006"
                     /evalue="6.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="detF"
                     /protein_end="607"
                     /protein_start="587"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTH"
     CDS_motif       2335..2424
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0007"
                     /evalue="5.90E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="detF"
                     /protein_end="806"
                     /protein_start="776"
                     /score="47.3"
                     /tool="antismash"
                     /translation="PPGIAGEVFLAGDCLARGYLHRPGLTAERF"
     CDS_motif       2506..2568
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0008"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="detF"
                     /protein_end="854"
                     /protein_start="833"
                     /score="33.3"
                     /tool="antismash"
                     /translation="YAGRRDDQIKLRGFRIEPGEV"
     aSDomain        2860..3066
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_PCP.1"
                     /evalue="3.20E-19"
                     /label="detF_PCP.1"
                     /locus_tag="detF"
                     /protein_end="1020"
                     /protein_start="951"
                     /score="60.8"
                     /tool="antismash"
                     /translation="ELALHRIWRNLLLHPSIGVSDDFFDVGGTSISAIKLAHTIGTEFG
                     RELPIRDVILHPTIEAQAALLRAD"
     aSDomain        3124..3774
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_Thioesterase.1"
                     /evalue="5.40E-30"
                     /label="detF_Thioesterase.1"
                     /locus_tag="detF"
                     /protein_end="1256"
                     /protein_start="1039"
                     /score="97.3"
                     /tool="antismash"
                     /translation="RVVCVHPAGGTAFCYLPLSAALPEDAGVVGIQSPGLGPGEEPLPS
                     VEAMAEEYLRLVAPQPGEVLVLCGLSYGGLVAYEMGRRLAKRHPRVSVVLLDTAGTDDP
                     AARAAIGPVPAAEFREKLVRFNGMYPGIEDAQIERYHRTYNHNRHTAREHDPGESAARV
                     VFVQATGEDTIPGGDEFWRRRVLGEFEVVPVGCGHWDLLESAALPRVAELITAE"
     CDS_motif       3301..3375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0009"
                     /evalue="6.00E-06"
                     /label="NRPS-te1"
                     /locus_tag="detF"
                     /protein_end="1123"
                     /protein_start="1098"
                     /score="18.8"
                     /tool="antismash"
                     /translation="QPGEVLVLCGLSYGGLVAYEMGRRL"
     gene            3786..12152
                     /gene="detG"
     CDS             3786..12152
                     /EC_number="2.3.1.39"
                     /NRPS_PKS="Domain: AMP-binding (9-384). E-value: 9.6e-86.
                     Score: 279.7. Matches aSDomain:
                     nrpspksdomains_detG_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (488-554). E-value: 1.9e-09. Score:
                     29.5. Matches aSDomain: nrpspksdomains_detG_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (570-826). E-value:
                     1.2e-41. Score: 134.5. Matches aSDomain:
                     nrpspksdomains_detG_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (974-1352). E-value:
                     1.6e-73. Score: 239.4. Matches aSDomain:
                     nrpspksdomains_detG_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1450-1514). E-value: 3.7e-12.
                     Score: 38.1. Matches aSDomain: nrpspksdomains_detG_PCP.2"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (1530-1930). E-value:
                     7.6e-130. Score: 425.4. Matches aSDomain:
                     nrpspksdomains_detG_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KR (2265-2423). E-value: 1e-27.
                     Score: 89.1. Matches aSDomain:
                     nrpspksdomains_detG_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (2494-2543). E-value:
                     4.2e-10. Score: 31.9. Matches aSDomain:
                     nrpspksdomains_detG_PP-binding.1"
                     /NRPS_PKS="Domain: Thioesterase (2578-2784). E-value:
                     1.5e-20. Score: 66.4. Matches aSDomain:
                     nrpspksdomains_detG_Thioesterase.1"
                     /codon_start=1
                     /gene="detG"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     246.4; E-value: 7.4e-75)"
                     /gene_kind="biosynthetic"
                     /product="malonyl CoA-acyl carrier protein transacylase"
                     /protein_id="DAC80525.1"
                     /sec_met_domain="Condensation (E-value: 2.2e-31, bitscore:
                     97.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.6e-91, bitscore:
                     292.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.2e-12, bitscore:
                     34.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 5.5e-131, bitscore:
                     425.4, seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIARRIHDRARLHPDALAVSDGSRRLTYAQLDAGAAAVAEALS
                     RKGVRPGDAVAVALPRSAELVQVMLGVLRLGGQVVPLDRQSPPARRDVILADSGAAVVV
                     DDELPPAELLAESAVPADPAPASFLFYTSGTTGRPKGVEVRDAGIVRLAEPGWLDPGTR
                     FASLANPAFDAISFEVWVPLLAGGTCVILDDDTVRDPRAFADALVRERIDTMFVTATLF
                     NAVAETVPDSFSTVRRVLVGGEQLNAAVIRRWYQANPDAPTRLQNGYGPTETTTFALSY
                     PIPRDFDGDVVPIGRPLPGTGAVAVTPDQRVAAEGEVAELYLSGAGVAPGYRGLPAETG
                     ERFVRLPWFDDGRARFYRTGDLVRVLPGGLFAYAGRTDRQVKVRGFRIEPGELEQRLLA
                     HPEIRQAHVAVRRAATAELLAFVVTGGLSYDAFEAHLSDTVPSYMRPHLVFRVEELPRN
                     ANGKVDEPALLASGFPPWRPGSSGEATSWQREILDVVEEVLGLPDARPEDTWLRSGGDS
                     LKALRLRFAIRERWGADLAPSVVQRGTFADLASAVTAARRPPYPELAAPTIATTAPATS
                     EQQRLWLLQQRNPGSTAYHVPLAFRITGEADLHQNVRAVVERHPALRTAFEARPEGLRQ
                     VAKAPYDPWIEPDDDFFTAPFDLASGRLLRAAWRPETDGSSTFLLCLHHIAVDGWSLNV
                     LFRELSGGAPNPGAHTPFDFAGWQSRWFASPAYHAQRASLAARLPDDPGSAGDASLAGR
                     LRITTIERTRVDEWAGELGLTRFQLLLGVFASSLYAVTGRTRPRIASPVANRPMREFED
                     SVGMFANTVRLPMAVDPDEDLDPQLRRLGAAAGTVLDHQDVAFADLEPAQAAFDYLFVL
                     ENTDFAALKVPGCPISPQWIEAAEAKCALTLSVVERPDGFDCLWEYGDGHFTAAEAEAL
                     GEVFARALTEGGTPAELAEPYRRGLPDHGRGEPAELAWDTVAEGFARQVARTPDAPALV
                     GDTTLSYAELDAHAARLAAVLPDDATDVALYFRPSAEHVVALLALARLNITAVPLDPGY
                     PPALLREVLERVQPRCVLLAPGDAFDTDIERHFVTLTDGPVPDVPARRAGRPLYTLFTS
                     GSTGAPKGVRVPDRTLANLIQWQDAPPAATQQFSMLSFDVSFQEIFTTLCGGGRLHLVR
                     PEWRHDVPALLDQLETAGIERLFLPYVALQLLAEHGARARRYPSRLRDVVTAGEQLVCT
                     PAIRRWFAGLPGVRLHNHYGPTETHVVSALTLDGNPEQWPERPAIGRPVANTALRVADA
                     TGAPLPPGQIGELLIGGLPANRCYLGEAAEEKFAELPELYYRSGDLAHFDHSGLLHFDG
                     RADRQVKLSGHRVELGQVEAALLRHPDVVNVVVAADGDRLTAYLESRRATTTAELVAHL
                     TPLLPPHARVDRFRVVAALPRTPSGKLDRDAAPRTPGEDLQRAAGHPSELAVLFEEVTG
                     VPIGPDETFFAAGATSLSLMRFHLRCAEAGYRFTVADLFEHVTLRDLTRHLESGAAPAP
                     VADSAGTDEPVAIIGMAVRLPGAPDLAAFWNLTREGRRGIEEFAATEGLVGARSLLDRP
                     LGFDPEHFGISHRDAALMDPQQRQLLMCSVEALAHAGIARAAGRVGLIAGCGENTYFQQ
                     MLREADPAALPDGFQLALHHEKDFLATKVAYHLDLTGPVLTTQTACSSSLVAVHQAAGM
                     LRGGEADVMLAGGVLVDVTLAEGYRYRPQHIFSADGHCRPFSDDADGTVGGSGVGVVVL
                     KPLSKARHDGDTVYAVITGSALTNDGAVKQGYSAPSPAGQREAIRAALQRAGRSGADVG
                     YVETHGTGTRLGDPIEVAALREAMPDSAGCALSSVKSQIGHLGAAAGVVGLIRATLAVH
                     HGVLPPTVDFRASNPALDLGPFRIPTEAEPWPAGPRVAGVSSFGIGGTNAHVVVESSRP
                     VPRAPADPARRVVLSARSATALRLDAQRVADYLAAHSESYVDVLRHLQSGRAEGRWRVT
                     AACADAAAAVAWLRTAEPQEVEAEGGRTSAPAPWDFPPPAFAERDFDFPRRATVSRLPE
                     GDWLHQPTWVRLRRATGTAERTERILVLSGPLPAPALDAGYRRVVRVHAADHFTRSGPD
                     TFEADPADPADLRRVLDALPGAEIDWVHTLPLGITGPVAEGSLAQARWACLDTPAALLR
                     AIDGRPVRTWWVSAGAVPANGAVTRPEAGLLAGVTAVGPQESGVRGHWVDLPDPGLDAL
                     AGLLTGPPPPQRVALRGGFWWTQEAVPVSASERILADGTYLILGGTGGIGTAIGEVILT
                     RTTGRVILLAREPRLPAALEPWADRVDLLAADLTTDRIDVDGPLAGIVHAAGVPDSGLI
                     ATRSPDPQAAKLAGALLTERLIEQHRPAVAVYCSSLSAQFGGTGQLDYAAANGFLDALA
                     HLDGPTERLSIGWDVWRDTGMAVTALESDTRHQAHLKVGLSSEEGRRTFSRALGSGLPH
                     LLVATTGLDAARTFHERDTQAPAPATDPEAELTEEVRALLGAAELDPDVPLYDLGADSL
                     MLLDVVDSVKRLFGVDLDLAWLGPEVTMTALLAKLSTAEDTSDVVVQQWREGRDAVCLV
                     HPVGGDVHAYRPLVEALDPSLGVCVIADPALNRPEPPGWSVAERARRYHAALHTQFPGY
                     RWQLAGWSFGAWVVAGMAAEAEAAGQPVRALHLIDPPPPGASTADYDDTQLEAVFRREL
                     GGAADDHARRLARACRANLDSMAGHELPRLTATASHVWLATEPEPGLPVADRTGWQALL
                     PDPSRWHELPATHYRIVAATAIADALSAP"
     aSDomain        3813..4937
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_AMP-binding.1"
                     /evalue="9.60E-86"
                     /label="detG_AMP-binding.1"
                     /locus_tag="detG"
                     /protein_end="384"
                     /protein_start="9"
                     /score="279.7"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="DRARLHPDALAVSDGSRRLTYAQLDAGAAAVAEALSRKGVRPGDA
                     VAVALPRSAELVQVMLGVLRLGGQVVPLDRQSPPARRDVILADSGAAVVVDDELPPAEL
                     LAESAVPADPAPASFLFYTSGTTGRPKGVEVRDAGIVRLAEPGWLDPGTRFASLANPAF
                     DAISFEVWVPLLAGGTCVILDDDTVRDPRAFADALVRERIDTMFVTATLFNAVAETVPD
                     SFSTVRRVLVGGEQLNAAVIRRWYQANPDAPTRLQNGYGPTETTTFALSYPIPRDFDGD
                     VVPIGRPLPGTGAVAVTPDQRVAAEGEVAELYLSGAGVAPGYRGLPAETGERFVRLPWF
                     DDGRARFYRTGDLVRVLPGGLFAYAGRTDRQVKVR"
     aSModule        3813..5447
                     /complete
                     /domains="nrpspksdomains_detG_AMP-binding.1"
                     /domains="nrpspksdomains_detG_PCP.1"
                     /locus_tags="detG"
                     /monomer_pairings="ile -> ile"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4167..4217
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0001"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="detG"
                     /protein_end="144"
                     /protein_start="127"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FLFYTSGTTGRPKGVEV"
     CDS_motif       4590..4613
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0002"
                     /evalue="3.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="detG"
                     /protein_end="276"
                     /protein_start="268"
                     /score="4.5"
                     /tool="antismash"
                     /translation="YGPTETTT"
     CDS_motif       4731..4814
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0003"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="detG"
                     /protein_end="343"
                     /protein_start="315"
                     /score="26.9"
                     /tool="antismash"
                     /translation="GEVAELYLSGAGVAPGYRGLPAETGERF"
     CDS_motif       4902..4967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0004"
                     /evalue="2.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="detG"
                     /protein_end="394"
                     /protein_start="372"
                     /score="32.8"
                     /tool="antismash"
                     /translation="YAGRTDRQVKVRGFRIEPGELE"
     aSDomain        5250..5447
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PCP.1"
                     /evalue="1.90E-09"
                     /label="detG_PCP.1"
                     /locus_tag="detG"
                     /protein_end="554"
                     /protein_start="488"
                     /score="29.5"
                     /tool="antismash"
                     /translation="REILDVVEEVLGLPDARPEDTWLRSGGDSLKALRLRFAIRERWGA
                     DLAPSVVQRGTFADLASAVTA"
     aSDomain        5496..6263
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.20E-41"
                     /label="detG_Condensation_LCL.1"
                     /locus_tag="detG"
                     /protein_end="826"
                     /protein_start="570"
                     /score="134.5"
                     /tool="antismash"
                     /translation="TAPATSEQQRLWLLQQRNPGSTAYHVPLAFRITGEADLHQNVRAV
                     VERHPALRTAFEARPEGLRQVAKAPYDPWIEPDDDFFTAPFDLASGRLLRAAWRPETDG
                     SSTFLLCLHHIAVDGWSLNVLFRELSGGAPNPGAHTPFDFAGWQSRWFASPAYHAQRAS
                     LAARLPDDPGSAGDASLAGRLRITTIERTRVDEWAGELGLTRFQLLLGVFASSLYAVTG
                     RTRPRIASPVANRPMREFEDSVGMFANTVRLPMA"
     aSModule        5496..8327
                     /complete
                     /domains="nrpspksdomains_detG_Condensation_LCL.1"
                     /domains="nrpspksdomains_detG_AMP-binding.2"
                     /domains="nrpspksdomains_detG_PCP.2"
                     /locus_tags="detG"
                     /monomer_pairings="pro -> pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5559..5663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0005"
                     /evalue="7.00E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="detG"
                     /protein_end="626"
                     /protein_start="591"
                     /score="31.3"
                     /tool="antismash"
                     /translation="TAYHVPLAFRITGEADLHQNVRAVVERHPALRTAF"
     CDS_motif       5829..5885
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0006"
                     /evalue="1.30E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="detG"
                     /protein_end="700"
                     /protein_start="681"
                     /score="30.5"
                     /tool="antismash"
                     /translation="LHHIAVDGWSLNVLFRELS"
     CDS_motif       6177..6248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0007"
                     /evalue="3.00E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="detG"
                     /protein_end="821"
                     /protein_start="797"
                     /score="26.1"
                     /tool="antismash"
                     /translation="IASPVANRPMREFEDSVGMFANTV"
     aSDomain        6708..7841
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_AMP-binding.2"
                     /evalue="1.60E-73"
                     /label="detG_AMP-binding.2"
                     /locus_tag="detG"
                     /protein_end="1352"
                     /protein_start="974"
                     /score="239.4"
                     /specificity="consensus: pro"
                     /tool="antismash"
                     /translation="FARQVARTPDAPALVGDTTLSYAELDAHAARLAAVLPDDATDVAL
                     YFRPSAEHVVALLALARLNITAVPLDPGYPPALLREVLERVQPRCVLLAPGDAFDTDIE
                     RHFVTLTDGPVPDVPARRAGRPLYTLFTSGSTGAPKGVRVPDRTLANLIQWQDAPPAAT
                     QQFSMLSFDVSFQEIFTTLCGGGRLHLVRPEWRHDVPALLDQLETAGIERLFLPYVALQ
                     LLAEHGARARRYPSRLRDVVTAGEQLVCTPAIRRWFAGLPGVRLHNHYGPTETHVVSAL
                     TLDGNPEQWPERPAIGRPVANTALRVADATGAPLPPGQIGELLIGGLPANRCYLGEAAE
                     EKFAELPELYYRSGDLAHFDHSGLLHFDGRADRQVKLS"
     CDS_motif       7089..7139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0008"
                     /evalue="4.80E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="detG"
                     /protein_end="1118"
                     /protein_start="1101"
                     /score="19.2"
                     /tool="antismash"
                     /translation="YTLFTSGSTGAPKGVRV"
     CDS_motif       7515..7541
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0009"
                     /evalue="1.80E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="detG"
                     /protein_end="1252"
                     /protein_start="1243"
                     /score="5.2"
                     /tool="antismash"
                     /translation="YGPTETHVV"
     CDS_motif       7653..7721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0010"
                     /evalue="2.40E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="detG"
                     /protein_end="1312"
                     /protein_start="1289"
                     /score="10.4"
                     /tool="antismash"
                     /translation="PPGQIGELLIGGLPANRCYLGEA"
     CDS_motif       7809..7871
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0011"
                     /evalue="2.50E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="detG"
                     /protein_end="1362"
                     /protein_start="1341"
                     /score="26.2"
                     /tool="antismash"
                     /translation="DGRADRQVKLSGHRVELGQVE"
     aSDomain        8136..8327
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PCP.2"
                     /evalue="3.70E-12"
                     /label="detG_PCP.2"
                     /locus_tag="detG"
                     /protein_end="1514"
                     /protein_start="1450"
                     /score="38.1"
                     /tool="antismash"
                     /translation="ELAVLFEEVTGVPIGPDETFFAAGATSLSLMRFHLRCAEAGYRFT
                     VADLFEHVTLRDLTRHLES"
     aSDomain        8376..9575
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="7.60E-130"
                     /label="detG_PKS_KS.1"
                     /locus_tag="detG"
                     /protein_end="1930"
                     /protein_start="1530"
                     /score="425.4"
                     /tool="antismash"
                     /translation="VAIIGMAVRLPGAPDLAAFWNLTREGRRGIEEFAATEGLVGARSL
                     LDRPLGFDPEHFGISHRDAALMDPQQRQLLMCSVEALAHAGIARAAGRVGLIAGCGENT
                     YFQQMLREADPAALPDGFQLALHHEKDFLATKVAYHLDLTGPVLTTQTACSSSLVAVHQ
                     AAGMLRGGEADVMLAGGVLVDVTLAEGYRYRPQHIFSADGHCRPFSDDADGTVGGSGVG
                     VVVLKPLSKARHDGDTVYAVITGSALTNDGAVKQGYSAPSPAGQREAIRAALQRAGRSG
                     ADVGYVETHGTGTRLGDPIEVAALREAMPDSAGCALSSVKSQIGHLGAAAGVVGLIRAT
                     LAVHHGVLPPTVDFRASNPALDLGPFRIPTEAEPWPAGPRVAGVSSFGIGGTNAHVVVE
                     S"
     aSModule        8376..12137
                     /domains="nrpspksdomains_detG_PKS_KS.1"
                     /domains="nrpspksdomains_detG_PKS_KR.1"
                     /domains="nrpspksdomains_detG_PP-binding.1"
                     /domains="nrpspksdomains_detG_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="detG"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       8808..8855
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0012"
                     /evalue="1.00E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="detG"
                     /protein_end="1690"
                     /protein_start="1674"
                     /score="14.7"
                     /tool="antismash"
                     /translation="GPVLTTQTACSSSLVA"
     CDS_motif       9231..9278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0013"
                     /evalue="4.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="detG"
                     /protein_end="1831"
                     /protein_start="1815"
                     /score="12.4"
                     /tool="antismash"
                     /translation="YVETHGTGTRLGDPIE"
     CDS_motif       10014..10088
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0014"
                     /evalue="1.80E+00"
                     /label="C2_DCL_024-062"
                     /locus_tag="detG"
                     /protein_end="2101"
                     /protein_start="2076"
                     /score="0.9"
                     /tool="antismash"
                     /translation="LVLSGPLPAPALDAGYRRVVRVHAA"
     misc_feature    10512..10514
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10581..11054
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PKS_KR.1"
                     /evalue="1.00E-27"
                     /label="detG_PKS_KR.1"
                     /locus_tag="detG"
                     /protein_end="2423"
                     /protein_start="2265"
                     /score="89.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTYLILGGTGGIGTAIGEVILTRTTGRVILLAREPRLPAALEPWA
                     DRVDLLAADLTTDRIDVDGPLAGIVHAAGVPDSGLIATRSPDPQAAKLAGALLTERLIE
                     QHRPAVAVYCSSLSAQFGGTGQLDYAAANGFLDALAHLDGPTERLSIGWDVWRD"
     CDS_motif       10914..11003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0015"
                     /evalue="4.20E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="detG"
                     /protein_end="2406"
                     /protein_start="2376"
                     /score="38.6"
                     /tool="antismash"
                     /translation="VYCSSLSAQFGGTGQLDYAAANGFLDALAH"
     aSDomain        11268..11414
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PP-binding.1"
                     /evalue="4.20E-10"
                     /label="detG_PP-binding.1"
                     /locus_tag="detG"
                     /protein_end="2543"
                     /protein_start="2494"
                     /score="31.9"
                     /tool="antismash"
                     /translation="ELTEEVRALLGAAELDPDVPLYDLGADSLMLLDVVDSVKRLFGVD
                     LDLA"
     aSDomain        11520..12137
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_Thioesterase.1"
                     /evalue="1.50E-20"
                     /label="detG_Thioesterase.1"
                     /locus_tag="detG"
                     /protein_end="2784"
                     /protein_start="2578"
                     /score="66.4"
                     /tool="antismash"
                     /translation="VCLVHPVGGDVHAYRPLVEALDPSLGVCVIADPALNRPEPPGWSV
                     AERARRYHAALHTQFPGYRWQLAGWSFGAWVVAGMAAEAEAAGQPVRALHLIDPPPPGA
                     STADYDDTQLEAVFRRELGGAADDHARRLARACRANLDSMAGHELPRLTATASHVWLAT
                     EPEPGLPVADRTGWQALLPDPSRWHELPATHYRIVAATAIADA"
     CDS_motif       11712..11768
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0016"
                     /evalue="2.90E-03"
                     /label="NRPS-te1"
                     /locus_tag="detG"
                     /protein_end="2661"
                     /protein_start="2642"
                     /score="10.2"
                     /tool="antismash"
                     /translation="WQLAGWSFGAWVVAGMAAE"
     gene            12177..13049
                     /gene="detH"
     CDS             12177..13049
                     /EC_number="1.14.11.17"
                     /codon_start=1
                     /gene="detH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121:dioxygenase, TauD/TfdA (Score: 273.9; E-value:
                     2.3e-83)"
                     /gene_kind="biosynthetic-additional"
                     /product="alpha-ketoglutarate-dependent taurine
                     dioxygenase"
                     /protein_id="DAC80526.1"
                     /transl_table=11
                     /translation="MEQYELDAVSRITTRPAPGYRTFTVHGLTPVIGAEVSGLDLTREL
                     TGEQLTELKTAFLDYHVLVFRDQDITGEDHKRLAASFGELRPVNPPPEHGDPYILEVAT
                     APEAANVFGNGWHADGTADAEPSLGSMLHITRMPDPGSGGDTLFANMHLAYDMLSPKMK
                     EFLADLTAVHDGALAFRGHQIPAGYQVPVSEHPLVVRHPETDRQLLYVNPAYTSHIPQL
                     SADESRAVLDLLFSLVPNRPMLACRVRWAPNTLVFWDNRCVQHHATYDYYPHTRYGTRV
                     AINGGPLKG"
     CDS             13066..14286
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 356.7; E-value:
                     2.5e-108)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative cytochrome P450 hydroxylase"
                     /protein_id="DAC80527.1"
                     /sec_met_domain="p450 (E-value: 3e-25, bitscore: 76.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHNRCPVVDVRDPAVLGDPMGGYDRILAESPVCWARLPSGEEGW
                     LITRSEDVRAVLSDPAVRNDPTGLPGPGAQTQEQAFLALGTPPEHLPYLRASLLSLDGA
                     EHTRLRRSISHAFGAARVASLRPRVQEIVDGLLDGLDPAASVNLIDDYAYPLAMAVVCE
                     LVGVPEKDWADWWHWGKVLVGGDPAQITPTLGEMFSYCHALVDQRRAEPRRDLLSEVVA
                     QDDLIDVDIVAVVVFLVLAGHETMAHMLSNGALALMRDPAQRELLRTEPALWPAAVREL
                     VRTDGPVQLARLRYAATDLVVGGVQIRAGDAVQVVLGAANRDPAQFAHPHHADVRWQAE
                     HGGSEGSVGFGWGPHFCLGVALAKVEAEVALRSLFERFPAVHPVSEPEWVPLPRGRHRV
                     ALDVHLR"
ORIGIN
        1 tcctcgatgc aggtgtccgc accgctgtcg tccggtcagc agcgtttgtg gacggtgtcc
       61 cagctcaccg aggcaggctc ggcctacaac gaaaccatgg cgttcaccct tcgcggtcca
      121 ctcgaccgtg cagcgttgcg ccgggccctc gacgccctcg ccgaacggca cgaaaccttg
      181 cggacccgct tcgccgtcga ggacgggcaa ccggtgcaga tcgtcctcga cgagactggt
      241 ttcccgtgca ctgtcaccga tgtgaccgga cagccggagg acaaggcagc gctgcgccgt
      301 accgaaccgt tcgagccgtt cgacctcgca agcgctccac cggcccgggc ccggctgctc
      361 atcgacggcc ccgagcacca cattctgctg atcaccgtgc accacatcgt cttcgacggc
      421 tggtcccgca cggtgctcct gcgcgagctc ggcgtcctct acaccgccga gctgcgtggc
      481 gacctggcgg acctgccgga gactcgtccg taccgggaat acgcacgggc acaacaggat
      541 tggctcgccg gtccggctcc gcagccgcac gagacgtact ggggcgaccg gctcgatggc
      601 gtcccggcag tgctggatct ccctgccgac cgcccgcgtc cggcccggca ggactatcgc
      661 ggagcccggg tccgcgtctc cctcgggcca cacctcaccg ctgcggtgaa gaagctggca
      721 cgcgagcacg gtgtcacgcc ctattccgcg gtcctgacct gctggtcgat gctgctgtcc
      781 cggctttccg ggcaggatga catcgttgtc ggtgtgccga cggccaaccg cggcgggggc
      841 ggcgagtacc cggccacgat cggatttttc gtcaacaccc ttgccgtgcg ggcggatctg
      901 ggcggcggtg tgaccggcgc ggtgctgctc aagcaggtcc gggcggcgct ccggggcgcg
      961 atcgaccacg tcggcctgcc gttcgagcgg gtcgtcgagc tggtgaaccc gccacgcagc
     1021 ccggcgcaca cgccgttgtt ccagaccatg gtcgcgtggg tgccgacggt gcacgacctc
     1081 ctggagctgc cgggagtggc cgccgaaccg ctcgaagtgg agcacgcgcc cgcgaagttc
     1141 gacctggcac tcggcatggc cgacgaggac ggcgacatca ccgggcatct cgactacgcc
     1201 gtcgccctct tcgaccatgc cacggcgcag cggtacgcgc ggtatttcgt ccggctgctc
     1261 gaacagctcg tcgcacgtcc ggacgctgaa gccacgagct acgaactcct ggacgaggcc
     1321 gaacggcgcg aaattctcgc ctggagcgcc gggccgcgcc cgaatcgccg gccgggcggg
     1381 ctcgtggagc ggttcacggc ccatgccgat gctgccccgg acgcccccgc cctcgtctgc
     1441 gacggccgga ccagcacgta cggcgaactc gaccagcgca ccacccggct ggccaatgcc
     1501 ttgcgcgccc gcggcgtcgg gccgggcgag gtggtggcaa tccacagtga acggtcgacg
     1561 gaactggtgg tcgccgtgct gggcgtgctg aaggcgggcg cggcgtacct ccccctcgac
     1621 ccggcccagc cgcccgcccg gcgcgaggcg atgatcgagg acgcacgtcc ggccctcgtg
     1681 ctgcgtgacg acccggattc aattgcggct ctcgccgccg aaggagaccc gaagcggcga
     1741 ctggtgccgg ccgggcccgg cgaaaccgcg tacgtcatct acacctcagg ctcgaccggg
     1801 cgtcccaagg gggtcgccgt cacccaccac agcgttctcg ccctgttcga ccagtggctt
     1861 gaccgcttcg gcgcgacccc gggtgaggcg acgtcggcgt ggtccggcat cggcttcgac
     1921 gcctcggtgc acgaactgct gcttcccctc accaccggcg ccgtgctgca cgtggtgccc
     1981 gaggacgtcc gggccgatcc ggcggcactg ctggcgtggt tgcgggaaca ccaggtggtg
     2041 caggcctttc tgccgccctc ctatgtccgg tggatcgacg aggacccggc ccgcgcggcc
     2101 gggctggcgc tgcggcatgt gctcaccggg gtcgaacccc tgccggaggc cgcgctcgcc
     2161 cggttcgccg cggccgtgcc cggcctccgg atctgtttcg gctacgggcc gaccgaggcc
     2221 acgctgtacg ccaccgccca cttcgacccg cagccggtcg accgcccggc gccgatcgga
     2281 cggccgctgc ccgggtcgcg gatgtacctg ctggacgaac ggctgcggcc ggtcccgccg
     2341 gggatcgccg gtgaggtgtt cctggccggg gactgcctgg cgcgcgggta tctgcaccgg
     2401 ccggggctca ccgcggaacg gttcgtgccg gacccgttcg cgccgggcga gcggatgtac
     2461 cgcaccggtg acctggcccg ctggctgccg agcggggaag ccgagtacgc cggccgccgc
     2521 gacgaccaga tcaagctgcg cgggttccgc atcgaacccg gagaggtgac ggccgcgctg
     2581 ctcgcggtgc ctggggtccg cgaggcggcc gtgctggtgg accgcgccgg tgagccaaag
     2641 ctcgtagccg gagtggcggg cggtggccgg acgctgcacg aatggcgcgc ggcgctggcc
     2701 gaccggctcc cggactacat gatcccgtcc gtgttcgccg agttcgaccg gctgccgctc
     2761 aaccccagcg gcaaactcga ccgcgacgcc gtgctggcgc aggcgcgggc gagcaccgcc
     2821 gtcaacaccg tcaacaccgc cgcgccgcgc gaccacgtcg aactcgcgct gcaccggatc
     2881 tggcggaacc tgctgctgca cccgtcgatc ggcgtgtcgg acgacttctt cgacgtcggc
     2941 ggcacctcga tctcggcgat caagctcgcc cacaccatcg gcacggagtt cggccgtgag
     3001 ctgccgatcc gggacgtgat cctgcacccg accatcgagg cgcaggccgc gctgctccgg
     3061 gcggacgaac cggcaagcgc cggtggcagc ctgatcgagt tccgccgcgg caccggccgg
     3121 gcgcgcgtcg tgtgcgtgca tccggcgggt gggacggcat tctgctacct gccgctcagc
     3181 gcggcgctgc ccgaggacgc cggggtcgtc gggatccagt cgcccgggct cggccccggt
     3241 gaggagccgc tgccgagtgt cgaggcgatg gccgaggagt acctgcggct cgtcgcgccg
     3301 cagcccggtg aggtcctggt cctgtgtgga ctgtcctacg gcggcctggt cgcctacgag
     3361 atgggccggc ggctcgcgaa gcggcatccg cgggtcagcg tcgtcctgct cgacaccgcg
     3421 ggcaccgacg accccgccgc gcgggccgcg atcgggccgg tcccggcggc cgagttccgc
     3481 gagaaactgg tgcggttcaa cggaatgtac ccgggcatcg aggacgcaca gatcgagcgc
     3541 taccaccgca cgtacaacca caaccggcac accgcccgcg agcacgaccc cggcgaatcg
     3601 gccgcgcggg tggtgttcgt gcaggccacc ggcgaggaca cgatcccggg tggcgacgag
     3661 ttctggcgcc gccgcgtgct cggcgagttc gaggtggtcc cggtcggctg cgggcactgg
     3721 gacctgctcg aaagcgccgc gctgccacgg gtcgcggagc tgatcaccgc cgaactggcg
     3781 gaccgatgac ctcgatcgcc cgccgcatcc acgaccgggc ccggctgcac ccggacgcac
     3841 tcgccgtgtc cgatggttcc cgccgcctca cctacgccca gctcgacgcc ggagccgccg
     3901 cggtcgcgga agcgttgtcc cgcaaggggg ttcgcccggg ggatgccgtc gcggtcgcgc
     3961 tgccgcggtc ggcagagctg gtgcaggtca tgctcggggt gctgcggctg ggtgggcaag
     4021 tcgtgccgct ggaccggcag agcccgcccg cccgccggga cgtgatcctt gccgactcgg
     4081 gggcggcggt ggtcgtcgac gacgagctgc cgcctgctga actacttgcc gaatccgccg
     4141 tcccggccga ccccgctccg gcgtcgttcc tcttctacac ctccggcacg accgggcggc
     4201 ccaaaggggt cgaggtgcgg gacgcgggca tcgtccggct ggccgagccg ggctggctcg
     4261 accccggcac gcgcttcgcg tcactggcca atccggcatt cgacgcgatc agcttcgagg
     4321 tctgggtccc gctgctcgcc ggcggcacgt gcgtgatcct cgacgacgac accgtccggg
     4381 acccgcgggc gttcgccgac gcgctggtcc gcgaacgcat cgacacgatg ttcgtcaccg
     4441 ccacgctgtt caacgccgtc gccgaaaccg tgccggacag cttctcgacc gtgcgccggg
     4501 tcctggtcgg cggcgagcag ctcaacgcgg cggtgatccg ccgctggtac caggccaatc
     4561 cggatgcgcc gacccggctg cagaacgggt acggccccac cgagaccacg acgttcgcgc
     4621 tcagctaccc cattccgcgg gacttcgacg gcgacgtggt gccgatcggc cgtccacttc
     4681 cgggcaccgg tgcggtggcg gtgacgccgg accagcgcgt ggccgccgag ggcgaggtcg
     4741 ccgagctgta tctgtcggga gcaggggtcg cgcccggcta ccgcggcctg cccgcggaaa
     4801 ccggggagcg gttcgtgcgg ctgccgtggt tcgacgacgg ccgcgcacgg ttctatcgca
     4861 ccggtgacct ggtgcgcgtg ctgcccggcg ggctgttcgc ctacgccggg cggaccgacc
     4921 ggcaggtgaa ggtccgcggg ttccggatcg agccgggcga gctggagcag cggctcctcg
     4981 cgcatccgga gatccggcaa gcccacgtcg ccgtccgccg cgcggccacg gcggagctgc
     5041 tcgccttcgt cgtcaccggc ggtctttcct acgacgcatt cgaagcgcac ttgagcgata
     5101 ccgtgccgtc gtacatgcgg ccgcacctcg tcttccgggt cgaggagctg ccccggaacg
     5161 cgaacgggaa ggtcgacgaa cccgcgctcc tggccagtgg attcccgccg tggcggccgg
     5221 gcagcagcgg cgaagcgacg tcgtggcagc gcgagatcct ggacgtcgtc gaggaagtgc
     5281 tcggccttcc ggacgcccgg cccgaggaca cctggctgcg gtccggcggt gattcgctca
     5341 aggcgttgcg gctgcggttc gcgatccgcg agcgctgggg tgcggacctg gcgccgtcgg
     5401 tggtccagcg tggcacgttc gccgacctcg cgtccgcggt cacggccgca cgtcgtccgc
     5461 cctacccgga gcttgccgcg ccgaccatcg ccaccacagc gcccgcgacc agcgaacaac
     5521 agcggctttg gctgctgcag caacgaaatc cggggtcgac ggcgtaccat gtgccgcttg
     5581 ccttccggat caccggcgag gccgacctgc accagaacgt ccgcgcggtc gtcgaacggc
     5641 acccggcgct gcggacggcg ttcgaagcca gacccgaggg tctgcggcag gtggcgaaag
     5701 cgccgtatga cccgtggatc gaaccggacg acgacttctt caccgcaccg ttcgacctcg
     5761 cgtcgggccg gctgctgcgg gcggcgtggc ggccggagac cgacggttcg agcacgtttc
     5821 tgctgtgcct gcaccacatc gcggtcgacg gctggtcgct gaacgtgctc ttccgtgagc
     5881 tgtccggcgg cgctccgaat cctggcgcgc acacgccgtt cgacttcgcc gggtggcagt
     5941 cgcggtggtt cgcctcccct gcctaccacg cccagcgggc atcgctggcc gctcggctcc
     6001 ccgacgaccc cgggtccgcc ggcgacgcgt cactcgccgg gcggctgcgg atcaccacga
     6061 tcgagcgcac gcgggtcgac gaatgggccg gtgagctggg cctgacccgg ttccagctcc
     6121 tgctgggcgt gttcgcctcc agcctgtacg cggtgaccgg gcggacccgg ccgcggatcg
     6181 cgtcgccggt ggcgaaccgg ccgatgcggg agttcgagga cagcgtcggg atgttcgcca
     6241 ataccgtgcg gctgccgatg gcggtggacc cggacgaaga cctcgacccc cagctccggc
     6301 ggctcggcgc ggcggcgggc acggtattgg accaccagga cgtcgcgttc gccgacctcg
     6361 aaccggcgca ggcggcgttc gactacctgt tcgtcctgga gaacaccgac ttcgccgcgc
     6421 tgaaggtacc cgggtgcccg atcagtccac aatggatcga agcggccgag gccaagtgcg
     6481 cgctcacgct gtcggtcgtg gaacggccgg acggcttcga ctgtctctgg gagtacggcg
     6541 acggccactt caccgcggcc gaagccgagg cgctcggcga ggtgttcgcc cgcgccctca
     6601 ccgaaggcgg gaccccggcc gagctggcgg agccgtaccg ccgcgggttg cccgaccacg
     6661 gccgcggcga accggcagag ctggcctggg acaccgtcgc ggaagggttc gcgcggcagg
     6721 tcgcacggac tcccgacgct ccggctttgg tcggcgacac gacgctgtcc tacgccgagc
     6781 tggacgcgca cgcggcccgc ctcgccgctg tcctccccga cgacgccact gatgtcgcgc
     6841 tgtacttccg gccgtcggcg gaacacgtcg tcgcgctgct tgcgctggcg cggctgaaca
     6901 tcaccgcggt gccgctcgac cccgggtatc cgcccgcgtt gctgcgcgaa gtactcgagc
     6961 gggtccagcc gcggtgtgtg ctgctcgccc cgggcgacgc cttcgacacc gacatcgaac
     7021 ggcacttcgt cacgctgacc gacgggccgg tgccggacgt tccggcccgc cgcgccgggc
     7081 ggccgctcta cacgctgttc acctccggct cgacgggcgc acccaagggc gtccgggtcc
     7141 cggatcgcac actggccaac ctcatccaat ggcaggacgc gccgcccgcg gccacgcagc
     7201 agttctcgat gctgtcgttc gacgtgtcgt tccaggagat cttcacgacc ctctgtggcg
     7261 gcggccggct gcacctggtc cgcccggagt ggcggcacga cgtcccggcc ctgctcgacc
     7321 agctcgaaac cgccgggatc gaacgcctct tcctgccgta tgtcgcgctc cagctgctgg
     7381 ccgagcacgg cgcgcgggcc cggcgttacc cgtcgcggct gcgggacgtg gtcaccgcgg
     7441 gcgagcagct ggtgtgcacc ccggcgatcc gccgctggtt cgccggcctg cccggcgtgc
     7501 ggctgcacaa ccactacggt cccaccgaaa cgcacgtggt gagcgcgctg accctcgacg
     7561 gcaacccgga gcagtggccc gagcggcccg cgatcggacg tccggtggcg aacaccgcac
     7621 tgcgggttgc cgacgccacg ggcgcgccct tgccgccggg gcagatcggc gagctgctga
     7681 tcggtggtct cccggcgaac cggtgctacc tgggcgaagc ggccgaggag aagttcgccg
     7741 aactacccga gctgtactac cgcagcggcg acctcgcgca tttcgaccac tccgggctgc
     7801 tgcacttcga cggccgcgcc gaccggcagg tcaagctcag cgggcaccgg gtggagctcg
     7861 ggcaggtgga ggccgcgctg ctgcggcatc cggacgtcgt gaacgtcgtc gtcgcggcgg
     7921 acggggaccg gctgaccgcg tacctggaat cccggcgcgc gaccaccact gccgagctcg
     7981 tcgcgcacct cacgccgctg ttgccgccgc acgcgcgcgt cgaccggttc cgggtcgtcg
     8041 ccgcgctgcc gcgcacgccc agcgggaagc tcgatcgcga cgcggcaccg cggacccccg
     8101 gcgaagacct ccagcgggcc gccgggcacc cgagcgagct tgcggtgctg ttcgaggaag
     8161 tgaccggggt gccgatcggc cccgacgaga cgttcttcgc cgccggtgcc acgagcctgt
     8221 cgctgatgcg gtttcacctg cgctgcgccg aggcggggta ccggttcacc gtggccgatc
     8281 ttttcgagca cgtcaccctc cgggacttga cccggcatct ggagagcggt gccgcccccg
     8341 cgccggtcgc ggattcggca ggcaccgacg agccggtggc catcatcggg atggcggtac
     8401 ggctgccggg cgcgccggat ctggccgcgt tttggaacct gacaagggaa ggccgccgcg
     8461 gtatcgagga attcgcggcg accgaggggc tggtcggtgc gcgcagtctg ctggaccggc
     8521 cgctggggtt cgaccccgaa catttcggga tcagccaccg ggacgcggcg ctgatggacc
     8581 cgcagcaacg gcagctgctg atgtgctcgg tcgaagcgct ggcgcacgcc gggatcgccc
     8641 gtgcggcggg gcgggtcggg ctgatcgcgg gctgcggcga gaacacgtac ttccagcaga
     8701 tgctgcgcga ggccgacccg gccgcgctgc cggacggctt ccagctcgcc ctccaccacg
     8761 agaaggattt cctcgccacg aaggtcgcct accatctcga tctgaccggc cccgtgctca
     8821 cgacccagac cgcctgctcg agttcgctcg tcgccgtgca ccaggccgcc gggatgctgc
     8881 gaggcggcga agcggacgtg atgctggcgg gcggggtcct cgtcgatgtc acgctggccg
     8941 aggggtaccg ataccggccg cagcacatct tctccgcgga cgggcattgc cgcccgttca
     9001 gcgacgacgc ggacgggacg gtcggcggca gcggtgtcgg cgtggtggtg ctgaagccgc
     9061 tcagcaaggc acgccacgac ggcgacacgg tgtacgcggt gatcacgggc tccgcgctga
     9121 ccaacgacgg cgccgtgaaa cagggttaca gcgcgccttc cccggccggg caacgagaag
     9181 cgatccgggc cgcgctgcag cgagccggac ggtccggtgc ggatgtcggg tacgtggaaa
     9241 cccatggaac cgggacacgt ctgggcgacc cgatcgaggt cgccgcgctg cgcgaagcga
     9301 tgccggactc ggccggatgt gcgctgtcgt cggtgaagag ccagatcggc cacctcggcg
     9361 cggcagcggg agtggtcggc ctgatccgcg cgacgctggc cgtccaccac ggcgtcctcc
     9421 cgccgaccgt cgatttccgc gcctcgaacc ccgcgctgga cctgggcccg ttccggatcc
     9481 cgaccgaggc cgagccgtgg cccgcgggcc cgcgcgtggc gggggtgagc agcttcggga
     9541 tcggcgggac caacgcgcac gtggtggtgg aatcatcccg gccggtgcca cgtgcgcctg
     9601 ccgatccggc ccgccgcgtg gtgctttccg cgcgcagcgc gactgccttg cgcctcgacg
     9661 cccaacgggt ggcggactac ctggccgccc actctgagtc ctatgtggac gttcttcggc
     9721 acctgcagtc cggccgcgcg gagggccgtt ggcgcgtgac cgcggcgtgt gccgatgcag
     9781 cggcggccgt ggcgtggttg cgcacggcgg aaccacagga ggtcgaagcg gaggggggtc
     9841 gtacgtcggc tccggcgccg tgggacttcc ctcccccggc ctttgccgaa cgggacttcg
     9901 acttcccgcg gcgggccacc gtctcgcggc tgcccgaggg cgactggctg caccagccca
     9961 cctgggtccg cctccgccgg gccaccggaa ccgccgagcg caccgaacgg atcctggtcc
    10021 tcagcggccc gctacccgca ccggccttgg acgcggggta ccggcgagtc gtgcgcgtcc
    10081 acgcggccga tcacttcacg aggtcggggc cggacacctt cgaagccgac cccgccgacc
    10141 ccgcggacct gcgccgggtg ctcgatgcct tgcccggcgc ggagatcgac tgggtccaca
    10201 cgctgccgct cggcatcacc ggacccgtcg ccgaaggctc ccttgcccaa gcgcgctggg
    10261 cctgcctcga cactccggcc gcgctcctgc gggccatcga cggccgcccg gtgcggacat
    10321 ggtgggtttc cgccggggcg gtacccgcga atggcgccgt cacgcggccc gaagccgggc
    10381 tgctcgccgg ggtgactgcc gtggggccgc aggaaagcgg cgtacgcggg cattgggtcg
    10441 atctccccga tcccggcctg gacgctctcg ccggactgct gaccgggcca cctccgccgc
    10501 agcgggtcgc gttacgaggc gggttctggt ggacgcagga agcggtaccg gtgtccgcga
    10561 gcgagcgcat tctcgccgac gggacgtacc tcatcctcgg cggcaccggc ggcatcggga
    10621 ccgccattgg cgaggtaatc ctgacccgga ccaccggccg cgtcattctg ctggcccgcg
    10681 aaccccggct cccggcggcg ctcgaaccgt gggcggaccg cgtcgacctg ctcgccgctg
    10741 atctgaccac cgaccggatc gacgtcgacg gaccgctcgc cggaatcgtc cacgccgccg
    10801 gggtacccga cagcggtctc atcgccaccc gcagcccgga cccgcaggcc gccaaactcg
    10861 ccggtgcctt gctcaccgag cggctgatcg aacagcaccg gcccgcggtc gccgtttact
    10921 gttcctcgct gtccgcccag ttcggcggca ccggacagct ggattacgcc gctgccaacg
    10981 gattcctcga cgcactcgcc cacctcgacg gcccgaccga gcggctgtcg atcggctggg
    11041 acgtatggcg cgacaccggc atggccgtca ccgccttgga atccgacacc cggcaccagg
    11101 cgcacctgaa ggtcggcctc agctccgaag aaggtcgccg caccttctct cgcgcgctcg
    11161 ggtccggact gccgcacctg ctcgtcgcaa ccaccggtct cgacgccgcc cgcacgttcc
    11221 acgagcgcga cacccaagcc ccggccccgg ccaccgatcc cgaagcggaa ctcaccgagg
    11281 aagtccgcgc gcttctcggc gccgccgaac tcgacccgga cgtgccgctg tacgacctcg
    11341 gcgccgattc cctgatgctg ctggacgtcg tcgactcggt gaaacgcctc ttcggtgtcg
    11401 acctcgacct tgcctggctc ggccccgagg tgacgatgac cgcgctgctc gcgaagttgt
    11461 ccaccgccga ggacaccagc gacgtcgtgg tgcagcaatg gcgtgaagga cgggacgcgg
    11521 tgtgtctcgt gcatccggtc ggcggtgacg tgcatgcgta ccgtccgctc gtcgaggccc
    11581 tggacccgag cctcggtgtc tgcgtgatcg ccgaccctgc cttgaaccgg ccggaaccac
    11641 cgggctggtc cgtcgcagaa cgggcccgcc ggtaccacgc cgccctgcac actcaattcc
    11701 ccggctaccg ctggcaactg gccggatggt cgttcggtgc ctgggtggtg gccgggatgg
    11761 ccgccgaggc cgaggcggcc gggcaaccgg tgcgggcact gcacctcatc gaccccccgc
    11821 cgcccggcgc cagtaccgcg gactacgacg acacccagct ggaggccgtg ttccggcggg
    11881 agctcggcgg cgccgccgac gaccacgccc ggcggctcgc ccgggcctgc cgcgccaacc
    11941 tcgacagcat ggccggacac gagctgcccc ggctcaccgc gaccgccagc cacgtctggc
    12001 tggccaccga acccgaaccc ggcctgccgg tcgccgaccg caccggctgg caggccctgc
    12061 tccccgaccc gagccgctgg cacgaactgc ccgcgacgca ctaccgcatc gtggcggcca
    12121 ccgccatcgc cgacgcactg tccgccccct gaaacccctg ggagggaaag gaaaccatgg
    12181 agcagtacga actcgacgcc gtcagccgga tcacgacgcg gcccgcgccc ggctaccgga
    12241 cgttcaccgt ccacggcctc accccggtga tcggcgccga ggtctccggc ctcgacctga
    12301 cccgcgaact caccggcgaa cagctcaccg agctgaagac cgccttcctc gactatcacg
    12361 tcctcgtgtt ccgcgaccag gacatcaccg gcgaggacca caaacggctg gccgcgagct
    12421 tcggtgagct gcgcccggtc aacccgccgc ccgaacacgg cgacccgtac attctggagg
    12481 tcgcgaccgc gcccgaagcg gccaacgtct tcggcaacgg ctggcacgcc gacggcaccg
    12541 ccgacgccga gccatccctc ggctcgatgc tccatatcac gcgcatgccc gacccgggca
    12601 gcggcggcga caccctgttc gccaacatgc acctcgccta cgacatgctg tcgccgaaga
    12661 tgaaggagtt tctcgcggac ctcacggcgg tgcacgacgg cgcgctcgcg ttccgcggtc
    12721 accagatccc ggcgggctac caggtcccgg tgagcgagca cccgctggtc gtgcggcacc
    12781 cggaaaccga ccggcagctg ctgtacgtca accccgccta cacctcgcac atcccccagc
    12841 tctcggccga cgagagccgc gcggtcctcg acctgttgtt ctccctggtg ccgaaccggc
    12901 cgatgctcgc gtgccgcgtg cggtgggcgc cgaacacgct ggtgttctgg gacaaccgct
    12961 gcgtccagca ccacgcgacc tacgactact acccgcacac ccgctacggc acccgcgtcg
    13021 cgatcaacgg cggcccgctc aagggctgac cagggaagga tttccgtgca gcacaaccgg
    13081 tgccccgtcg tggacgtgcg cgacccggcc gtcctcggcg acccgatggg cggctacgac
    13141 cgcatcctcg ccgagtcgcc ggtctgctgg gcccgcctgc ccagcggcga ggaaggctgg
    13201 ctgatcaccc ggagcgagga cgtccgcgcc gtcctgtccg atccggccgt gcgcaacgat
    13261 cccaccggcc tgcccggacc aggcgcacaa acccaggagc aggccttcct cgcgctgggc
    13321 actccgccgg agcatctgcc atacctgcgc gcgagcctgc tcagcctcga cggcgccgaa
    13381 cacacccgcc tgcgccgcag catcagccac gcgttcggcg ccgcgcgggt cgcgagcctg
    13441 cgcccgcggg tgcaggagat cgtcgacggg ctcctcgacg gcctcgaccc ggccgcctcg
    13501 gtgaacctca tcgacgacta cgcctatccg ctggccatgg ccgtggtctg cgaactggtc
    13561 ggcgtccccg aaaaggactg ggcggactgg tggcactggg gcaaggtgct ggtcggcggc
    13621 gatccggcgc agatcacgcc cacgctcggc gagatgttct cctactgcca cgccctcgtc
    13681 gaccagcgcc gcgccgagcc gcgccgcgat ctgctcagcg aggtggtcgc ccaggacgac
    13741 ctcatcgacg tcgacatcgt ggccgtcgtg gtgttcctcg tgctggccgg gcacgaaacc
    13801 atggcgcaca tgctgtccaa cggagcgctc gcgctcatgc gcgatcccgc ccagcgagag
    13861 ctgctgcgca ccgagcccgc actgtggccg gcggcggtcc gcgaactggt gcgcaccgac
    13921 ggtccggtgc agctggcccg cctccgctat gccgcaaccg accttgtggt cggcggtgtg
    13981 cagatccggg ccggggacgc ggtgcaggtc gttctcggcg cagccaaccg ggatcccgcg
    14041 cagttcgccc atccgcacca cgccgacgtg cggtggcagg ccgagcacgg cggcagcgaa
    14101 ggcagtgtcg gattcggctg gggaccgcat ttctgcctcg gggtcgcact ggcgaaagtg
    14161 gaggccgagg tcgcgctgcg gagcctgttc gagcgctttc ccgccgtgca cccggtgtcc
    14221 gaaccggaat gggtgccgtt gccacgagga cggcaccggg tcgcgctgga cgtgcacctg
    14281 cgctaacgcg cgaaggcccc gaccggcatc atcacgtccg cgctcgccgc tccacagtcg
//
