BGC0001844: holrhizin biosynthetic gene cluster from Paraburkholderia rhizoxinica HKI 454
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 510,846 - 531,583 nt. (total: 20,738 nt).
This entry is originally from NCBI GenBank NC_014718.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001844
Short description holrhizin biosynthetic gene cluster from Paraburkholderia rhizoxinica HKI 454
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Other lipopeptide)
Loci NCBI GenBank: NC_014718.1
Compounds
  • holrhizin
Species Paraburkholderia rhizoxinica HKI 454 [taxonomy]
References
Chemical products information
holrhizin
(no structure information available)
C42H68N6O10
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • RBRH_RS20625
 511080 - 511298 (-) non-ribosomal peptide synthetase module
copy AA seq
copy Nt seq
  • RBRH_RS16800
  • WP_041754829.1
 511808 - 531508 (-) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
NRP-specific information
Subclass Other lipopeptide
Cyclic? no
Lipid moiety octanoic acid
NRP-synthases
Gene Modules
RBRH_RS16800
Module 1
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Starter
Module 2
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 3
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 4
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 5
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 6
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: Z7AIIJAM3U3HR6IYDPQOINM4, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Changed amino acid substrates to lower case
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.