BGC0001844: holrhizin biosynthetic gene cluster from Paraburkholderia rhizoxinica HKI 454
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Location: 510,846 - 531,583 nt. (total: 20,738 nt).
This entry is originally from NCBI GenBank NC_014718.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001844
Short description holrhizin biosynthetic gene cluster from Paraburkholderia rhizoxinica HKI 454
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Other lipopeptide)
Loci NCBI GenBank: NC_014718.1
Compounds
  • holrhizin
Species Paraburkholderia rhizoxinica HKI 454 [taxonomy]
References
Chemical products information
holrhizin
(no structure information available)
C42H68N6O10
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • RBRH_RS20625
511080 - 511298 (-) non-ribosomal peptide synthetase module
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  • RBRH_RS16800
  • WP_041754829.1
511808 - 531508 (-) non-ribosomal peptide synthetase
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NRP-specific information
Subclass Other lipopeptide
Cyclic? no
Lipid moiety octanoic acid
NRP-synthases
Gene Modules
RBRH_RS16800
Module 1
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Starter
Module 2
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 3
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 4
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 5
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 6
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: Z7AIIJAM3U3HR6IYDPQOINM4, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Changed amino acid substrates to lower case
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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