BGC0001848 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001848 (Micromonospora sp. B006)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	other,T3PKS	1	58,198	diazaquinomycin H/diazaquinomycin J	other:other	100%

BGC0001848 - Region 1 - T3PKS,other

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Location: 1 - 58,198 nt. (total: 58,198 nt) Show pHMM detection rules used

Region on contig edge.

other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 58,199
Label		BGC0001848

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001848	1.30	Other	diazaquinomycin H, diazaquinomycin J	Micromonospora sp. B006
BGC0000679	0.94	Terpene	diazepinomicin	Micromonospora sp. M42
BGC0002493	0.58	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0000286	0.50	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0000649	0.47	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002474	0.46	NRP	agrobactin	Agrobacterium tumefaciens
BGC0000343	0.44	NRP	enterobactin	Pseudomonas sp. J465
BGC0000252	0.44	Polyketide	nonactin	Streptomyces griseus subsp. griseus
BGC0001594	0.43	Alkaloid	fischerindole L	Fischerella muscicola UTEX 1829
BGC0001444	0.43	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001848	1.00	Other	diazaquinomycin H, diazaquinomycin J	Micromonospora sp. B006
BGC0000679	0.78	Terpene	diazepinomicin	Micromonospora sp. M42
BGC0002493	0.63	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0000286	0.62	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0002458	0.62	NRP	alazopeptin	Streptacidiphilus griseoplanus
BGC0000343	0.60	NRP	enterobactin	Pseudomonas sp. J465
BGC0000466	0.59	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0001076	0.57	Other (Nucleoside)	liposidomycin B, liposidomycin A, liposidomycin C, liposidomycin Z, liposidomycin H, liposidomycin G, liposidomycin L, liposidomycin M, liposidomycin K, liposidomycin N	Streptomyces sp. SN-1061M
BGC0000649	0.56	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001810	0.56	Polyketide	trehangelin	Polymorphospora rubra

Similar known gene clusters from MIBiG 4.0

NRPS/PKS substrates

NRPS/PKS substrate predictions

MicB006_2901

AMP-binding (70..270): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: TGAWFGESLK
Nearest Stachelhaus code(s):: nohBza or oh-nitroBza AGAWYAEPLK (71% 8Å match)
Stachelhaus code match:: 60% (weak)

MicB006_2938

AMP-binding (16..423): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SRTESTLPVK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)