LOCUS       BGC0001850             23503 bp    DNA     linear   BCT 12-FEB-2019
DEFINITION  Streptomyces sp. F001 ILLPAC_007, whole genome shotgun sequence.
ACCESSION   BGC0001850
VERSION     BGC0001850
KEYWORDS    .
SOURCE      Streptomyces sp. F001
  ORGANISM  Streptomyces sp. F001
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     Bacteria and source DNA available from Alessandra S. Eustaquio,
            University of Illinois at Chicago, 900 S Ashland Ave, MBRB 3102,
            Chicago, IL 606067.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 04:58:04
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..23503
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001850"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23503
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1069..1881)
                     /locus_tag="StrepF001_25885"
     CDS             complement(1069..1881)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138954.1"
                     /locus_tag="StrepF001_25885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyltransferase"
                     /protein_id="RZB16697.1"
                     /transl_table=11
                     /translation="MLDEVTTAAYLKRIAADRPDRPDLAALRHLHERHVMSVPFESLDY
                     HLGREIHYKDERIVDKIVHQRRGGACGETNSSFYFLLKALGFTVHVRHGRVWIGGKLRD
                     PYNHLLVMAEIEGARWLVDVGFGKGSRFPILLDSPEAQSDPHGVFSVRKVDDRATDVLR
                     DGKPQYRVYDDPTSLSDFDQVIHWYRTSPDSMLLQNMFCSLPLDDGWVVLKNDVLTITR
                     GTEKTTEKLPDDAAVLAAYEKWFGITLEKRPMPSPYLRDSVRMAFEEK"
     gene            complement(1912..2724)
                     /locus_tag="StrepF001_25890"
     CDS             complement(1912..2724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019854397.1"
                     /locus_tag="StrepF001_25890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyltransferase"
                     /protein_id="RZB16698.1"
                     /transl_table=11
                     /translation="MLDNKTVAAYLDRISAEPPKRLDADALRHLHERHVLSVPFDNLDY
                     HRGAEICMDERAVDKVVHEHRGGLCGEINTAFYFLLRSLGFDVTLHQGRVRIAEGVTTA
                     PYHHVLMTVAIDGVRWIADIGFGKSSRHPLRLDCDELQPDPHGEFRTRWLDRRSVEVQR
                     NGTPQYIVYDEPVELIDFRQTMWWYRTSPDSPFLQNLVCSLPLENGWVILRDDVLTVTT
                     GGERRTEKLPDDAAVLAAYEKWFGIRLEKRPAPSPHMNNAISFSFDSD"
     gene            complement(2731..3792)
                     /locus_tag="StrepF001_25895"
     CDS             complement(2731..3792)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF04909.12"
                     /locus_tag="StrepF001_25895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase"
                     /protein_id="RZB16699.1"
                     /transl_table=11
                     /translation="MPHSAPGISHSTPGIPHGTPGVRENSQTPAGKPWSRAIDVHHHIL
                     PDFYLDELENMGVRTILPGIDRPTWSADSSLAMMDRHGIRAAVVSVWPGVPAGLEPEPA
                     AEFARRVNEYLAELVAAHPGRFGAFATLPIPHTDLVLEEFEYAVDTLGLDGVGLVSNYA
                     GLYVGDRSMDPLFAAAARRRSPLFVHPTVPPSTGQPDFGLPASLYEFPFESVRVAAQLL
                     YNQTLERFPELPVILPHGGGGVPFYAGRLSCGGLISAALTDRLPEDPVGSLQRLYIDIA
                     MTGDPHALAALRSFAPANRILVGSDFPLMPESYTLDTGHRVVRHGGFSAEERTRLDHAN
                     AEGLFPRFTGKDG"
     gene            complement(3802..4206)
                     /locus_tag="StrepF001_25900"
     CDS             complement(3802..4206)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF14534.4"
                     /locus_tag="StrepF001_25900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="RZB16700.1"
                     /transl_table=11
                     /translation="MANPTGEKIALPTDPMQLPAAFEQAFNSGSLEAIKQLFDPQAVRV
                     LSPGNFQTGEEMWKAAAETLPDRLPVKLSVRHIYTVGDTALMICDYVHEGPGPDGKHMR
                     LEGTAADILRRGTDGVWRCLISNPPGTTRA"
     gene            4425..5105
                     /locus_tag="StrepF001_25905"
     CDS             4425..5105
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016909570.1"
                     /locus_tag="StrepF001_25905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H dehydrogenase"
                     /protein_id="RZB16701.1"
                     /transl_table=11
                     /translation="MVKVAIIFHSRSGNIFRLASAAAAAAEKAGAEPKLLKVPELPDPM
                     VLDKEAYAELEDATRDIPVATLDDLVAADAIMIGTPVHFGLPAPQILNFIDRSGPVAIP
                     GKLANKAATVFASGSAAHAGQQATILALHNVLCHWGCLIVPNGSSVEILASEHNGAPYG
                     TCSISRHAPDNVHEDNIKAIEYQTLRLVEVATAYQIGLQQTKSAIDFVDMDFLMKKFPR
                     LSVD"
     gene            5305..6009
                     /locus_tag="StrepF001_25910"
     CDS             5305..6009
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 80.5; E-value: 2.4e-24)"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961793.1"
                     /locus_tag="StrepF001_25910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="RZB16702.1"
                     /transl_table=11
                     /translation="MKLVIFGANGPTGRLATEQALAEGHSVTAVTRRPDAFPLSGAALR
                     VVGADIMDAEAVDRAVAGHDAVISTVGVPYTKEPVTVYSEGTANVVKAMQSHGIRRLVC
                     VSSIGVNYEDAPGEAFIFRKLIVPVLLKMGRPLYDDAARMEEIVRASDLDWTVIRPAGL
                     FDGTTTTDYVVSKTRHPGWFTSRKDLADALVREGVDHRNVGAVVEVITTQGVPSYFQVF
                     VKEALHIGGSKK"
     misc_feature    5434..5436
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6078..7082)
                     /locus_tag="StrepF001_25915"
     CDS             complement(6078..7082)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 362.5; E-value: 2.9e-110)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016909565.1"
                     /locus_tag="StrepF001_25915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="RZB16703.1"
                     /transl_table=11
                     /translation="MITCGAAHGARGVLGTGSYVPSRVINNKDMSSLVGVSEEAILRKT
                     GIRERRWAKPEEATSDLAVAAGRAALEQAGIRASDLGLIIVATSTPDSPQPATACVVAD
                     ELGAGNGTAAFDVNSVCSGFTFALSVAERMLADAPADHALVIGADVYSRILSPTDRRTT
                     VLFGDGAGAVVLGPGGRHRMLSTRLASFGTARELIGVPGGGSRMPATEETLREGKHYFS
                     MNGRGVTEFVETQVVPGIEAFLADNGVRHDEIAHFVPHQANGRLLESMTGHLGIPSDRL
                     ATTVTRYGNTGAASVPITLDHLARSGAVAAGDLVLLAAFGGGMSMGLTLLRAG"
     gene            complement(7318..8079)
                     /locus_tag="StrepF001_25920"
     CDS             complement(7318..8079)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239:TetR family
                     transcriptional regulator (Score: 193; E-value: 9.9e-59)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673412.1"
                     /locus_tag="StrepF001_25920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="RZB16704.1"
                     /transl_table=11
                     /translation="MRLAPTKSRERAVGVIVSKPRSSGRASSGAAQSVWLRRSPTPRNE
                     PPLSRERITEAAIALLDEEGMERLTMRHLAERLGVGATTLYWHIDTKDDVIDLAIDAIF
                     AEAPLPEGDTGSWQENVVALLSGCRAMLLRHPWSAALPLRRRPSIGPNFLTWLEFLQAT
                     LARAGFEGRQVQAACWVLYNHVQGSTASQSSLRWSGTERAAAQEQLRMQQDSYPTLVAY
                     EYMLDDAWDENFDLGLKYILDGLQAQIAASH"
     gene            8258..8905
                     /locus_tag="StrepF001_25925"
     CDS             8258..8905
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 57.6; E-value: 2.3e-17)"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:PF13460.4"
                     /locus_tag="StrepF001_25925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="RZB16705.1"
                     /transl_table=11
                     /translation="MKLVVFGADSPTGHLVTAMAAAEGHTVTAITRRPADFPFYDRGVQ
                     VADADLMDADAVDWVMWGHDAVISVIGAPPSRRPGTVHSQGVYNIVKAMVHHGLRRLVC
                     VSHAGLDAVDEPRRARLRRGAALLTGRRAAHQDVRRMESVVQESGLDWTLVRPGRLVSR
                     SGVTDYRIATHAAPRPVTSRADLAHALVREATARDHVRETVYVTTGHLLAAG"
     gene            9559..10689
                     /locus_tag="StrepF001_25930"
     CDS             9559..10689
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891163.1"
                     /locus_tag="StrepF001_25930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="RZB16796.1"
                     /transl_table=11
                     /translation="MPRADQRKKGVEYVRGLLEVPGRKSIRNIASLIGGRATDQSLHHF
                     ISESTWDWTPVRQALARYLVPRLPVEAWVVHSTVIRKAGQHSVGVDRRFVPAEGRVLNA
                     QQAVGVWAASGHRSSPVDWGLHLPQAWIDDRSLRSRASIPDSAEVETLSDRAAKLCVDL
                     VTEWAMPVRPVVLDACSLNAARLFDRLGRKGVPLLARVDPSVPLIVNDPALTGHRGSAS
                     MPAGEVIRAASGTRQPVRWRPGGRGAGIRSGLLASAAVKLPPERGGRLRSGHGRRLALI
                     GLAEGRQQDAPQLWLTSLTDHQPASLLTLFTLLDRVEYDYFEVAKSVGIEDYVGRSFDG
                     WHRHMTLASAAHAVAVLSSPGRVRNTPTCGATEPGT"
     gene            10578..12221
                     /locus_tag="StrepF001_25935"
     CDS             10578..12221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891162.1"
                     /locus_tag="StrepF001_25935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phospho-2-dehydro-3-deoxyheptonate aldolase"
                     /protein_id="RZB16706.1"
                     /transl_table=11
                     /translation="MAPAHDPRLGRPRRRRALLARPGAEHADVRGDGARHLTKCATACC
                     CRPPTTPGSGCRAGPPDAATPTSRERAGPADGRGGVAHRAGCGRGARRATPLPQQAPVR
                     RATALIDTPTAARPDHTEGQFAPIAPIRSSLRPHRLGRRGRTHAPVHPEWETSVDNPVL
                     DIGSKPARQQPGWEDKESVGRVRRQLLASPGLVDPEDVRTLRSVLTVVAAGRAHVVQAG
                     DCAEDPAQCTEGHVARKAGLLDVLAGELKGITHRPVVRAGRMAGQFGKPRSKPTEWVGE
                     LELPVYRGHMVNGPGPDPLSRRPDPRRMLDCYRASRAVLRHLGWHRAPGVPGIDPPVWT
                     SHEALVLDYEVPLVRRDSTGAPVLTSTHWPWIGDRTRQLDGAHVALLAAVANPVACKVG
                     PGMTASELLALCERLDPAREPGRLALIARMGAQLVAHRLPPLVAAVREAGHPVIWLCDP
                     MHGNTVTAPDGRKTRYLDWIVREVRDFRSAVLTARGVAGGLHLETTPDQVAECATDPSA
                     ADLDRGTYTSLCDPRLRPDQAVAAVSAWGT"
     misc_feature    10980..10982
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12287..13057
                     /locus_tag="StrepF001_25940"
     CDS             12287..13057
                     /EC_number="1.3.1.28"
                     /NRPS_PKS="Domain: PKS_KR (4-162). E-value: 8e-16. Score:
                     50.3. Matches aSDomain:
                     nrpspksdomains_StrepF001_25940_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     246.2; E-value: 6e-75)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467093.1"
                     /locus_tag="StrepF001_25940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="RZB16707.1"
                     /transl_table=11
                     /translation="MEGKVALITGAAGGIGAAVARALGERGVTVAAVDRDADGLLHTVQ
                     KLTADGVSARAFPADITGRAEVDALVDTVEQQLGPLDFLVNAAGVLHLGEARHLTDQDW
                     DATFAVNATGVFVVSRAVVNRMVPRRRGAIVTVASNAAGTARTQMAAYAASKAAATMFT
                     KCLGLEVAGHGIRCNLVAPGSTDTPMLSSMWRDNSGRRTTIAGRPEEYRVGIPLGKLAM
                     PSDVADAVAFLLSDRAAHITLHSLTVDGGATLGG"
     aSDomain        12299..12772
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_StrepF001_25940_PKS_KR.1"
                     /evalue="8.00E-16"
                     /label="StrepF001_25940_PKS_KR.1"
                     /locus_tag="StrepF001_25940"
                     /protein_end="162"
                     /protein_start="4"
                     /score="50.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALITGAAGGIGAAVARALGERGVTVAAVDRDADGLLHTVQKLTA
                     DGVSARAFPADITGRAEVDALVDTVEQQLGPLDFLVNAAGVLHLGEARHLTDQDWDATF
                     AVNATGVFVVSRAVVNRMVPRRRGAIVTVASNAAGTARTQMAAYAASKAAATMF"
     CDS_motif       12305..12367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_StrepF001_25940_0001"
                     /evalue="7.50E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="StrepF001_25940"
                     /protein_end="27"
                     /protein_start="6"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LITGAAGGIGAAVARALGERG"
     gene            13090..13755
                     /locus_tag="StrepF001_25945"
     CDS             13090..13755
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 264.1; E-value: 1.8e-80)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007923187.1"
                     /locus_tag="StrepF001_25945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismatase family protein"
                     /protein_id="RZB16708.1"
                     /transl_table=11
                     /translation="MTGKITTGTTPAGRTTGIPPIEPYELPSARELPDPVPPWRVDPGR
                     AVLLVHDMQHYFLRTLPEPLREQLLRNAVLLRTRCAALGMPVAYTAQPGAMDDAERGLL
                     KDFWGPGMQRSPADREITAELAPTGRDWMFTKWRYSAFFRSGLLERMRAHHRDQLVLCG
                     VYAHVGVLMTAVDAFSNDIETFLVADAVADFSAAHHRQALDYAARCCAVVSTAKEVIA"
     gene            13752..15617
                     /locus_tag="StrepF001_25950"
     CDS             13752..15617
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 321.8; E-value:
                     1.5e-97)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001147.1"
                     /locus_tag="StrepF001_25950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenazine-specific anthranilate synthase
                     component I"
                     /protein_id="RZB16709.1"
                     /transl_table=11
                     /translation="MTSDLLGRVLVAQPPPFALLHRSTAAGGGRLDVLVGEVHTWPTLD
                     AIALPEPSAAGPARHDVLALVPYRQVRERGFAAVDDGAPLLTLQVTDQDTVSAAEAPAR
                     LDRVPTPLLDGRFTPDDETYAATVREVIEREIGMGEGANFVIRRSYRARIGDYSLGSAL
                     SFFRNLLQTESGAYWTYLVHTGTRTFVGASPERHVSLSGGTAVMNPISGTYRYPPSGPR
                     LSELLDFLADRKETDELYMVLDEELKMMARVCEDGGRVVGPYLKEMARLAHTEYLIEGR
                     STRDPREILRETLLAPTVTGSPLESACRVIERYEPEGRGYYSGVAALIGRDAEGGRTLD
                     SAILIRTAEIDSAGRLEIGVGATVVRHSDPVSEAAETRAKAAGLLAALEDGRPDRFADH
                     PSVRTALAERNTSVADFWLADRGTPPPRTPAPAGTSVLVVDAEDTFTAMLDHQLRSLGL
                     AVTVRRYDESYALGDHDLVVLGPGPGDPRDAGHPKVARLRTVVDTLLAGHRPFLAVCFS
                     HQVLCTRLGFELVRRDVPNQGTRREIDLFGARESVGFYNTFAARAAEDKVECEGVGTVE
                     VSRDRETGEVHALRGPHFASVQFHAESVLTREGVRILAELLGNLV"
     gene            complement(15680..17062)
                     /gene="pcaB"
                     /locus_tag="StrepF001_25955"
     CDS             complement(15680..17062)
                     /EC_number="5.5.1.2"
                     /codon_start=1
                     /gene="pcaB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 183.9; E-value: 9.5e-56)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941784.1"
                     /locus_tag="StrepF001_25955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-carboxy-cis,cis-muconate cycloisomerase"
                     /protein_id="RZB16710.1"
                     /transl_table=11
                     /translation="MNDTLIDAGLLSPVRAGTPVEAAVCDLAWLQAMLDAEAALARAQA
                     RLGTVPPEAAEAITRAARADRLDLRALAVAARETANPVVGLVAALTAAVRSRSPAAAEY
                     VHRGSTSQDVFDTGAMLIARRALGIVLADLDTTADALARLAAEHRDTPMAGRTLALHAV
                     PTTFGLKAAGWRELVLAAGHRLRTVAGQLPVSLGGAAGTLAGYLASTALTGPDLDAYPD
                     RLITAFAEETGLARPVLPWHAVRTPMADLAAALAFTAGALGKIAVDVQSLVRTEVGEVA
                     EPAGPGRGRSSAMPHKRNPVLATLVRSAAIQVPPIAAGLTQCLVSEDERSAGGWHAEWQ
                     LLRECLRLAGGAAHTAVQLAEGLQVRPERMRENLELTGSRVVAERIAAVLAPRLGGAAA
                     RKLLDEASRKAEESGAALAEILGAMPEIGLDAEELADLCDPVGYTGAAGPLVDRALGGR
                     SR"
     gene            complement(17059..19008)
                     /locus_tag="StrepF001_25960"
     CDS             complement(17059..19008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489632.1"
                     /locus_tag="StrepF001_25960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding protein"
                     /protein_id="RZB16711.1"
                     /transl_table=11
                     /translation="MSAGRLRVCIVGAGPRGLCVLERLCAGERTARSHRSVTVHVVDPA
                     APGAGAVWRTDQSRQLLTNTVACQITVFTDAESRIEGPVEPGPSLYEWADSLARFGELG
                     GYDEAVLAEARTLRPDSYPTRAFYGQYLRDCFRQIVARAPEHVTVEVHRSRAVAMADTH
                     GTPGGPQGVRLADGTRIHELDAVVLALGHLPTQLTPRQERTASLARIHHLTYVPPANPA
                     DVDTSFAEAGEPVLLRGLGLNFFDHMALFTTGRGGVFDRLGDRLVYRPSGREPRLCASS
                     RRGVPYHARGENEKGAFGRHTPRLLTPETIAALRGRARGGERARFLSDVWPLIAAEVEG
                     VYYGTLLAARNAASEPFVRRYLTASPRQRPALLDEHGIGPADRWDWDRLARPCHGRAFA
                     GRAEFRGWLLEYLARDVREAKAGNVSGPLKAALDVLRDLRNEVRLVVDHSGLEGGSHLD
                     ELEGWYTPLNAFLSIGPPVSRIEEMIALIEAGILELTGPGTQIRVDTERPAFVAHSTLV
                     PGPPVRSAHLIEARLPPPDLRRTADPLLRHLLLTEQCRPHRIEGDCGVSHETGGLAVTE
                     RPCRVIDGQGRPHPRRFAYGVPTESVHWVTAAGVRPGVDSVTLADADAIARAVLTLSPA
                     RQGLGGTRLTEVVV"
     gene            complement(19005..20195)
                     /locus_tag="StrepF001_25965"
     CDS             complement(19005..20195)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 293.5; E-value: 4.4e-89)"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019854413.1"
                     /locus_tag="StrepF001_25965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding protein"
                     /protein_id="RZB16712.1"
                     /transl_table=11
                     /translation="MARMVVVGGGIGGLAAAVAVARRGHRAVVLERAEEFAEIGAGIQL
                     APNGLHALDRLGLGDAVRALAVHIDELRFMDGVTGEHVASMPLTGGYRRRFGNPYVVVH
                     RGELYRLLLDACRRSPAIELRAGSRATGYRQDGSAATVLLDGGGRVTGDAVIGADGIHS
                     AIRRRLVGDGAPRVAGITVYRTVIPMERVPEELRRNAVTWWAGPGCHFVHYAIGGGRYL
                     NLAPSVENGATEAFAAVPVEQARVLGELAALGGTAQRLLALGEHWKSWALVDRDPVDRW
                     TDGRVTLLGDAAHPMLHYAAQGACQALEDAVVLAGLLDDGADTIPDRFEKYNAERRERT
                     ARITHAARASTRLWHPAGAEAKARNEMLSALSGPALHDHVAWMHGAREFGADGARR"
     gene            complement(20204..21775)
                     /locus_tag="StrepF001_25970"
     CDS             complement(20204..21775)
                     /NRPS_PKS="Domain: AMP-binding (16-428). E-value: 3e-52.
                     Score: 169.4. Matches aSDomain:
                     nrpspksdomains_StrepF001_25970_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     178.2; E-value: 3.5e-54)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019854414.1"
                     /locus_tag="StrepF001_25970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA synthetase"
                     /protein_id="RZB16713.1"
                     /transl_table=11
                     /translation="MLLQRIGNRGIRLGTLFERAASRHPANVLILDHDLDLAPDLGRRA
                     TVAELADLVADVASRLWAAKIRPGERVVVHKSDTFDIPLLACAISRIGAVPVLLSPHLD
                     GDTVAELVRRADRPHLVTDQAKLDDELPAEVFDLAESVLLTSGTHARAVELEDFAGVRR
                     VTPVTMPADHPTLITHTSGTTGVPKLAVHTGRTLQARYRPQRLAITPVIRRRETVAMHV
                     SFVHSRLFTALAISLLNGLPIVVLADEDPDRAADLFARVRPGILEAHPNSYLRWEKLAD
                     DHRAPLANVKLFSSTFDAIHPRTVHRLLRASRRRAPLFGQLYGQSEVGPTVVRAFTRRH
                     APDADGRCVGMPFPGMTDVRVVSRDGRPPSEENPGYIEVRSDGRITTYLGEAERYARQL
                     DDGWWRMGDVGFRSKWGCLHLLDREVDLIPGFGSTLAAEDTLFAKLDELAEVIIIPGAD
                     GTAVPVVCTKDDSPLDREAWRQATAGLPAMADPVQWRLSDLPQTATTKIKRLQLAQLLA
                     AAGQGR"
     aSDomain        complement(20492..21727)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_StrepF001_25970_AMP-binding.1"
                     /evalue="3.00E-52"
                     /label="StrepF001_25970_AMP-binding.1"
                     /locus_tag="StrepF001_25970"
                     /protein_end="428"
                     /protein_start="16"
                     /score="169.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FERAASRHPANVLILDHDLDLAPDLGRRATVAELADLVADVASRL
                     WAAKIRPGERVVVHKSDTFDIPLLACAISRIGAVPVLLSPHLDGDTVAELVRRADRPHL
                     VTDQAKLDDELPAEVFDLAESVLLTSGTHARAVELEDFAGVRRVTPVTMPADHPTLITH
                     TSGTTGVPKLAVHTGRTLQARYRPQRLAITPVIRRRETVAMHVSFVHSRLFTALAISLL
                     NGLPIVVLADEDPDRAADLFARVRPGILEAHPNSYLRWEKLADDHRAPLANVKLFSSTF
                     DAIHPRTVHRLLRASRRRAPLFGQLYGQSEVGPTVVRAFTRRHAPDADGRCVGMPFPGM
                     TDVRVVSRDGRPPSEENPGYIEVRSDGRITTYLGEAERYARQLDDGWWRMGDVGFRSKW
                     GCLHLLDREVDLI"
     CDS_motif       complement(21200..21247)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_StrepF001_25970_0001"
                     /evalue="1.60E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="StrepF001_25970"
                     /protein_end="192"
                     /protein_start="176"
                     /score="11.6"
                     /tool="antismash"
                     /translation="ITHTSGTTGVPKLAVH"
     gene            complement(21854..22432)
                     /locus_tag="StrepF001_25975"
     CDS             complement(21854..22432)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (24-190). E-value:
                     5.2e-16. Score: 51.2. Matches aSDomain:
                     nrpspksdomains_StrepF001_25975_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623804.1"
                     /locus_tag="StrepF001_25975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="RZB16714.1"
                     /transl_table=11
                     /translation="MTDTELENFKDSKNLENLETTALFQVSAETHVRASADEVYATVSD
                     LPRSGEWSVECTGGQWVEGTPAAVGAVFRGENHRPADVVAWAPVVRGAWTTDSEVVAAE
                     PGRSFRWAIRDSSGRRQESVWSFDLRAADDGCVLVHSFWMGAPTEGIRGITADMAAHEK
                     QRFFSDWTAKLTADLAATVHRIKQAVERT"
     aSDomain        complement(21863..22360)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_StrepF001_25975_Polyketide_cyc2.
                     1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="5.20E-16"
                     /label="StrepF001_25975_Polyketide_cyc2.1"
                     /locus_tag="StrepF001_25975"
                     /protein_end="190"
                     /protein_start="24"
                     /score="51.2"
                     /tool="antismash"
                     /translation="QVSAETHVRASADEVYATVSDLPRSGEWSVECTGGQWVEGTPAAV
                     GAVFRGENHRPADVVAWAPVVRGAWTTDSEVVAAEPGRSFRWAIRDSSGRRQESVWSFD
                     LRAADDGCVLVHSFWMGAPTEGIRGITADMAAHEKQRFFSDWTAKLTADLAATVHRIKQ
                     AVE"
     gene            complement(22507..23493)
                     /locus_tag="StrepF001_25980"
     CDS             complement(22507..23493)
                     /NRPS_PKS="Domain: PKS_ER (24-318). E-value: 2.2e-37.
                     Score: 120.7. Matches aSDomain:
                     nrpspksdomains_StrepF001_25980_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 240.4; E-value: 4.4e-73)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138970.1"
                     /locus_tag="StrepF001_25980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADPH:quinone reductase"
                     /protein_id="RZB16715.1"
                     /transl_table=11
                     /translation="MKAAYIERLGPADAIRVGDLPPPRGGPTDVLVDVLATPVNPVDTF
                     VRSGAWRTPVTFPFVIGRDLVGTVAAVGDGVAGFAVGDTVWCNSLGHAGRQGAAAQQAL
                     VPVDRLYRLPDAVPPTDAAAVLHPAATAHLALFAHGGLRAGERVLVAGAAGNVGSAAVV
                     LAAEAGARVIATAGAGDAEYCRTLGAQACADYRDPELPQRLRDLAPDGIDLLVDAAGWN
                     DLPAAVDLLAFRGRIVVLAGLRARPVLPVGPLYLKDATVTGFAISHATTAELADVARSV
                     NRLLARGSLRARAVEEAPLSAAAEAHARLERGELRGRRLVLRPDLDS"
     aSDomain        complement(22540..23421)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_StrepF001_25980_PKS_ER.1"
                     /evalue="2.20E-37"
                     /label="StrepF001_25980_PKS_ER.1"
                     /locus_tag="StrepF001_25980"
                     /protein_end="318"
                     /protein_start="24"
                     /score="120.7"
                     /tool="antismash"
                     /translation="GGPTDVLVDVLATPVNPVDTFVRSGAWRTPVTFPFVIGRDLVGTV
                     AAVGDGVAGFAVGDTVWCNSLGHAGRQGAAAQQALVPVDRLYRLPDAVPPTDAAAVLHP
                     AATAHLALFAHGGLRAGERVLVAGAAGNVGSAAVVLAAEAGARVIATAGAGDAEYCRTL
                     GAQACADYRDPELPQRLRDLAPDGIDLLVDAAGWNDLPAAVDLLAFRGRIVVLAGLRAR
                     PVLPVGPLYLKDATVTGFAISHATTAELADVARSVNRLLARGSLRARAVEEAPLSAAAE
                     AHARLERGELRGR"
     CDS_motif       complement(22999..23061)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_StrepF001_25980_0001"
                     /evalue="7.00E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="StrepF001_25980"
                     /protein_end="165"
                     /protein_start="144"
                     /score="18.6"
                     /tool="antismash"
                     /translation="GERVLVAGAAGNVGSAAVVLA"
ORIGIN
        1 cgcgggacgt ccaggccggc gacgtccgcc gcgaggaggt cgtccgggag ccggaagacc
       61 agcgagccga agaggaaccc ggcgccgatc gcgccgagca cgacgacatc gccgcgccgg
      121 gcgcggccct cgcgggccag ccgccacagc gccgtcagcg gcgaggcggc cgcggtgttg
      181 cccagggtgt cggcggtgac ggggacgcgc tcggcatcgg cgccggccat ccgcccgatc
      241 tgccgtacca gcttggcgtt ggcctggtgg acggcgaagc cgctcacctc gtccacggtg
      301 acgccggccg tcgagagcgc ctcgctgagg gacttgggca cccgggtcat cgcctcccgc
      361 agcaccacgt tgccgtccat gaagatgtac ggcgtccggg gtgtctcggt cgtcgacgac
      421 ggcacctcct ggtccaggcg ccaggccgtc gccacgcgga cggcgtccga gtacacgttg
      481 ccgaggtcgt agctgagcag cccgtccccg ccgggcgcct tgcgcagcac cacggcgccg
      541 gcggcgtccc cgaagaagat ccgcgtgatg cggtcggtcg ggtcggtgat gccggagccg
      601 cgttccgcgc agacgaccaa cgccgtttcc aggtccggct cctgcagcag ggatgcggcc
      661 gtgtagatgc cgtacgccgc cgaggcgcag gcgtgctggg tcaggtcgag gatgcgcggg
      721 gtgtcgatgc ccatgcgctc ggcgaggctc acgcccagcg acggcatgat ccagtccggg
      781 gtcgtgcacg cgacgagcac gacgtcgatc tcgcgggcct ggacgtcggc cgccgcgagg
      841 gccttctctg ccgcctcgac cgcgaggtca aggacggttt cgtggggttc caggaaacgg
      901 cgttcccgga ttcccgtctt cttctcgatc cactccggtg tggtgtccag cgtttcgcac
      961 agctcggcgt tcgtgaccac cctgtcgggc agcgccaggg cgacgctgcg gggactgacc
     1021 ggtgcgagtt cccacttggg catgacgacc tctcctcttc gcctggaact acttctcctc
     1081 gaacgccatg cgtacggagt ccctgagata ggggctcggc atgggccgct tctccagcgt
     1141 gatgccgaac catttctcgt acgcggccag caccgcggcg tcgtcgggga gtttctcggt
     1201 cgtcttctcc gtgcctcggg tgatggtcag aacgtcgttc ttgagcacga cccagccgtc
     1261 gtcaagcggc agcgaacaga acatgttctg caggagcatc gagtccgggc tggtgcggta
     1321 ccagtggatg acctggtcga agtccgagag ggaggtcggg tcgtcgtaga cccggtactg
     1381 cggctttccg tcgcgcagga cgtcggtggc gcggtcgtcc accttccgga cggagaacac
     1441 accgtgcggg tcggactgcg cctccggcga gtccaggagg atcggaaacc ggctgccctt
     1501 gccgaagccg acgtcgacga gccagcgcgc tccctcgatc tccgccatga ccagcaggtg
     1561 gttgtacgga tcgcgcagct ttccgccgat ccatacgcgc ccgtggcgta cgtggacggt
     1621 gaagcccagg gccttcagaa ggaagtagaa ggagctgttg gtctcgccgc aggcgccgcc
     1681 gcggcgctgg tgcacgatct tgtcgacgat cctttcgtcc ttgtagtgga tctccctgcc
     1741 gaggtgatag tcgaggcttt cgaacggcac cgacatcaca tgccgttcgt gcaggtggcg
     1801 cagcgcggcg aggtcggggc ggtccgggcg gtcggccgcg atgcgtttca gataggcggc
     1861 cgtcgtcact tcatccagca tgtgcgttgt cccctggtgg tgtgggatgg gtcagtcgct
     1921 gtcgaacgag aaactgatcg cgttgttcat gtgagggctc ggcgcggggc gtttctcgag
     1981 cctgatcccg aaccatttct cgtaggccgc cagcaccgcg gcgtcgtcgg ggagtttctc
     2041 ggtccgccgc tcccctccgg tggtgaccgt cagcacgtcg tcgcgcagga tgacccagcc
     2101 gttctccagg ggcagcgagc agacgaggtt ctgcaggaac ggagagtccg ggctggtccg
     2161 gtaccaccac atcgtctgcc ggaagtcgat cagctccacc ggctcgtcgt agacgatgta
     2221 ctgcggtgtc ccgttgcgct gcacctccac ggaccgccgg tccagccacc gcgtacggaa
     2281 ctcgccgtgc ggatcgggct ggagctcgtc gcagtcgagg cgcagggggt gccggctgct
     2341 cttgccgaac ccgatgtcgg cgatccaccg caccccgtcg atggccaccg tcatcaggac
     2401 atggtggtac ggcgccgtcg tgacgccctc cgcgatccgc acccggccct gatgcagggt
     2461 cacgtcgaag cccagcgacc ggagcaggaa gtagaacgcc gtgttgatct caccgcagag
     2521 gcctccgcgg tgttcgtgga ccaccttgtc gacggcgcgt tcgtccatac agatctcggc
     2581 accgcggtgg tagtcgaggt tgtcgaacgg caccgacagc acatgccgtt cgtgcaggtg
     2641 ccgcagcgcg tccgcgtcga ggcgtttcgg gggctcggcc gagatgcggt ccaggtaggc
     2701 ggcgacggtc ttgttgtcga gcacggcgtg tcatccgtcc tttccggtga agcgcgggaa
     2761 gaggccctcg gcgttcgcgt gatccagccg ggtccgctcc tcggcgctga atccgccgtg
     2821 ccgcacgacg cggtgaccgg tgtcgagggt gtacgactcg ggcatcagcg ggaagtccga
     2881 gccgaccagg atccggttcg ccggggcgaa ggagcgcagg gccgccagtg cgtgcgggtc
     2941 gccggtcatc gcgatgtcga tgtagagccg ttgcagcgag ccgacggggt cctcgggcag
     3001 ccggtcggtg agggccgcgc tgatgagtcc gccgcaggag agccggccgg cgtagaaggg
     3061 gacgccgcca ccgccgtgcg gcaggatcac gggcagctcg gggaatctct ccagggtctg
     3121 gttgtagagg agttgggcgg ccacccggac cgattcgaag gggaactcgt acagcgaggc
     3181 gggcaggccg aagtccggct ggccggtgga cgggggaacc gtcgggtgca cgaacagcgg
     3241 gctgcggcgg cgggccgcgg ccgcgaagag ggggtccatg gagcggtccc cgacgtacag
     3301 gccggcgtag ttgctgacga ggcccacgcc gtccaggccg agcgtgtcga cggcgtactc
     3361 gaattcctcg agcacgaggt ccgtatgggg aatgggcagc gtggcgaacg cgccgaaccg
     3421 gccgggatgt gcggcgacca gttcggcgag gtattcgttc acccggcgcg cgaactccgc
     3481 cgccggttcg ggttccaggc cggccggaac ccctggccag acgctcacca ccgcggcgcg
     3541 gatgccgtgc cggtccatca tggcgaggct gctgtccgca ctccacgtcg gccggtcgat
     3601 gccggggaga atggtccgga ctcccatgtt ctcgagttcg tcgagataga agtccgggag
     3661 gatgtggtgg tgcacgtcga tggcccgcga ccacggcttc ccggcgggtg tctgcgagtt
     3721 ttcccgcaca cccggagtgc cgtgcggaat acccggtgtg ctgtgcgaaa tacccggtgc
     3781 gctgtgcggc atacccgccc ctcaggcccg agtggtgccg ggcgggttgc tgatcaggca
     3841 gcgccagacg ccgtcggtgc cgcgccggag gatgtccgcc gcggtgccct ccaggcgcat
     3901 gtgcttgccg tccgggccgg ggccttcgtg cacgtagtcg cagatcatca gggccgtgtc
     3961 gccgaccgtg tagatgtgcc gcacggacag cttgaccggg agacggtcgg gcagggtctc
     4021 ggcggcggcc ttccacatct cctcccccgt ctggaaattg ccgggggaca gaacgcgcac
     4081 ggcctgcggg tcgaaaagct gcttgatggc ttcgaggctg cccgagttga aagcctgctc
     4141 gaaagccgcc ggaagctgca tgggatcggt cggaagagcg atcttctcgc ctgtgggatt
     4201 cgccatggaa acagcacagg gcaccgccgt ggagcactca accggcggcc gtccagtctg
     4261 tcaggtccgc cgggctccaa gtccccttgt ccgacgggct tttcggctac ctgacgaact
     4321 gtgtgacgtg ctcctgggca gccggttcgg gcggccgtga tgatgacgct tcgtatcccg
     4381 gggatgacgt tttcccggca acgacgaatg gtgaggagtg tcccatggtc aaagtggcca
     4441 tcatcttcca ttcccggagc ggaaacatct tccggctggc atcggcggcg gccgccgcgg
     4501 ccgagaaggc gggcgccgag cccaagctgc tcaaggtccc cgagctgccg gacccgatgg
     4561 tgctggacaa ggaggcgtac gccgaactgg aggacgccac ccgtgacatc cccgtcgcca
     4621 ccctggacga cctcgtggcg gcggacgcga tcatgatcgg tacgcccgtc cacttcggcc
     4681 tgccggcccc gcagatcctg aacttcatcg atcgctccgg accggtcgcc atcccgggga
     4741 agctggcgaa caaggccgcg accgtgttcg cgtccggctc cgccgcgcac gccggccagc
     4801 aggcgacgat cctcgccctg cacaacgtgc tgtgccactg gggctgcctc atcgtcccca
     4861 acggttccag cgtcgagatc ctggcgtccg agcacaacgg agcgccgtac ggcacctgca
     4921 gcatctcccg gcacgcgccg gacaacgtgc acgaggacaa catcaaggcg atcgagtacc
     4981 agaccctgcg cctggtcgag gtcgccaccg cctaccagat cgggctgcag cagacgaagt
     5041 ccgccatcga cttcgtcgac atggacttcc tcatgaagaa gttcccccgc ctgtccgtgg
     5101 actgaccgcg gaccgtcgca aggaaacggc acggaacacg cacccgcggc gcctcggccg
     5161 ggccgcgggt gcgtcgcatg ccgacgggcg gaaccccccg ctcctcagcc cctgacccca
     5221 ggaatggtac gttgttctag tgctagatca ctgtacgaat gcccgatcga tgtccggcac
     5281 gaagtcggct ggcaggagga actcgtgaaa ctggtcatct tcggcgcgaa cggcccgacc
     5341 gggcggctgg ccacggagca ggcactcgcc gagggccatt ccgtcaccgc cgtgacccgc
     5401 cgacccgacg ccttcccgct gagcggcgcc gcgttacggg tggtcggcgc ggacatcatg
     5461 gacgccgagg ccgtggaccg cgcggtggcc ggccatgacg cggtcatctc caccgtcggc
     5521 gtgccgtaca ccaaggagcc ggtgaccgtc tattcggagg gcaccgcgaa cgtcgtcaag
     5581 gccatgcagt cgcacggcat ccgacgcctg gtctgcgtca gctccatcgg cgtcaactac
     5641 gaggacgccc ccggtgaggc cttcatcttc cggaagctga tcgtgccggt gctgctcaag
     5701 atgggccgcc ccctgtacga cgacgcggcc cggatggagg agatcgtgcg cgccagcgac
     5761 ctggactgga cggtcatccg ccccgccggc ctcttcgacg gcacgaccac gaccgactac
     5821 gtcgtgagca agacccgcca cccgggctgg ttcacctcgc gcaaggacct cgcggacgca
     5881 ctggtccgcg aaggcgtcga ccaccgcaac gtcggcgccg tcgtcgaggt catcaccacc
     5941 cagggcgtgc ccagctactt ccaggtcttc gtcaaggagg ccctgcacat cggcggcagc
     6001 aagaagtaac cgccgcgcat gacacggccc ggccccgtcg agaacggggc cgggccgtgt
     6061 catgcgcggc cggtacgtca gccggcccgc agcagcgtca ggcccatcga catgccgccg
     6121 ccgaacgccg ccagcagtac caggtcaccc gcggccaccg ctcccgaacg ggccaggtgg
     6181 tccagggtga tggggacgga ggcggcgccg gtgttgccgt agcgcgtcac cgtggtggcc
     6241 agccggtcgg agggtatgcc caggtgcccg gtcatgctct ccaggagccg tccgttcgcc
     6301 tggtgcggca cgaagtgtgc gatctcgtcg tggcgcactc cgttgtccgc gaggaacgcc
     6361 tcgataccgg ggaccacctg cgtctcgacg aactcggtca cgccccggcc gttcatcgag
     6421 aagtagtgct tgccctcgcg cagcgtctcc tccgtcgcgg gcatccggct gccgccgccc
     6481 ggtacgccga tcagctcgcg ggcggtcccg aagctggcca gccgggtgga gagcatccgg
     6541 tgccggccgc ccgggcccag cacgacggca ccggcgccgt ccccgaacag cacggtcgtg
     6601 cgccggtcgg tgggcgagag gatgcgcgag tacacgtcgg cgccgatgac cagggcgtgg
     6661 tcggccgggg cgtcggcgag catccgttcg gcgacggaca gggcgaaggt gaagccgctg
     6721 cacaccgagt tgacgtcgaa ggcggcggtg ccgttgcccg cgcccagctc gtccgcgacc
     6781 acacaggccg tcgccggctg cggggagtcg ggagtggagg tcgccacgat gatgagaccg
     6841 aggtccgagg ccctgatgcc ggcctgctcc agggccgccc ggccggcggc caccgcgaga
     6901 tccgacgtgg cttcctcggg cttcgcccaa cgccgttcgc ggatccccgt cttccgcagg
     6961 atggcctcct cggagacacc gaccaggctg ctcatgtcct tgttgttgat gacgcgactg
     7021 ggtacgtagg accccgtacc gagcacgccc cgtgcgccgt gggcggcacc gcatgtgatc
     7081 atggtctgct ccaatgtcgt cccgtgtgcc ccgccgctca tggcggttcc gcccactgcc
     7141 gctcaaggcg ccgtgcgggg aacggcgtac cggggccggc ggatccgcat ggaatcagga
     7201 cagttcgcgc gctctgcgtg gtccagccgc tgcctgcgga tctgtcagat gagcacgggc
     7261 cgggggatca actccggcca cttcacgggg cgctacgcga cggagcgctg aggggcgtca
     7321 gtgcgaggcc gcgatctgcg cctggagtcc gtcgaggatg tacttcaggc cgagatcgaa
     7381 gttctcgtcc caggcgtcgt ccagcatgta ctcgtacgcg accagcgtgg gatagctgtc
     7441 ctgctgcatc ctcaactgct cctgtgcagc ggcccgttcg gtaccggacc agcgcaggct
     7501 ggactgactg gcggtggaac cctggacgtg gttgtacagt acccagcagg cggcctgaac
     7561 ctgccgcccc tcgaacccgg cccgcgccag ggtcgcctga aggaactcca gccaggtcag
     7621 gaagttcggt ccgatcgacg gccggcgacg caacggcagc gcggcggacc acgggtgccg
     7681 aaggagcatg gcccggcatc cggagaggag ggccaccacg ttctcctgcc agctgccggt
     7741 gtccccttcg gggagcgggg cctcggcgaa gatggcgtcg atcgccaggt cgatgacgtc
     7801 gtccttggtg tcgatgtgcc agtaaagggt cgtggcaccg actccgagac gctccgcaag
     7861 gtggcgcatg gtcaaccgct ccatgccctc ctcgtccagc agggcgatcg ccgcctcggt
     7921 gatgcgctcc ctggacagcg gcggctcgtt gcgcggcgtc ggcgagcggc gcagccagac
     7981 gctctgcgcg gctccggagc tcgcgcgacc gctgctccgc ggcttgctca cgatgacacc
     8041 caccgccctt tcccggctct tcgtaggggc gagcctcatg gtagtacatt gatcggcgcg
     8101 ctcgatcgat gtaccggcac ccgatcactg ttcgagaacc actgttcgaa gacgcgcagg
     8161 tcgagagccc gcagttcgaa aagcgccgca tccatgtgcg tcccccaccg cacccgcagg
     8221 cctggccgcg ctacgcccgt gcgcgaggag ggaaagcatg aaactggtcg tgttcggcgc
     8281 cgacagcccg accggtcacc tggtcaccgc catggcggcg gccgaaggtc acacggtcac
     8341 ggcgatcacc cggcgccccg ccgacttccc cttctacgac cgcggggtgc aggtcgccga
     8401 cgcggacctg atggacgccg acgcggtcga ctgggtcatg tggggccacg acgcggtcat
     8461 ctccgtgatc ggcgcgccac cgtccaggag acccggcacc gtccactcgc agggggtcta
     8521 caacatcgtc aaggcgatgg tgcaccacgg cctgcggcgg ctggtctgtg tcagccacgc
     8581 cggcctcgac gccgtcgacg agccgcgccg agcccggctg cgccgcggag ccgcgctgct
     8641 gaccggccga cgcgccgccc accaggacgt acggcgcatg gagagcgtcg ttcaggagtc
     8701 cggactcgac tggaccctgg tccgcccggg ccggctcgtc agccgcagtg gcgtcacgga
     8761 ctaccggatc gccacccacg cggcgccccg tccggtcacc tcccgagccg acctcgccca
     8821 cgccctggtc cgcgaggcca ccgcccgcga ccatgtgcgc gaaacggtct atgtcaccac
     8881 cggccatcta ctggccgccg gttgaccacc tgacgcccgt tgcgcctgga aacagccacc
     8941 cggactttcg ccgcggactc ggacagcacg ggggaatcgg gaatggcgtt gcgcttcgtt
     9001 ggctgaattg cggcggtcgg tggcgttgtc cgccgggtgt atcggcgacc atgccgcggc
     9061 gtcaacagtg ccggccacag ttcgtcatct tgacccgagc ggcccctgaa gctcttccgg
     9121 gcgaccgtcg cgttgtcgct cctcagtccc gtaggtgaca gatgcagatc caaacagtgg
     9181 tgcacagatc tacacatcga taaagttgcg cccgatttgg tccggtattg cggcatcggg
     9241 cgatgcgacc aaggcgtagg gacggtcggc cccggcggga ggggcacgac tgccgcacgc
     9301 ccggtgaatt gcggagattc cattcgcccc tgttcgcaca tatgcgaggg aagggtgcgc
     9361 cggaacgttt cgctcaacac atccgcgggc agattttcca gccagcggga gcagctatgc
     9421 gggggtcaat ctgtgaatgc atcctggttg ccgctgatta ctgtcgagaa ggggaacgag
     9481 aaatcgcatc gattattcac ggaaaccgaa gcgccagatg atttactgcg gcaaatatct
     9541 cggtccctct tcgtttccct gccgcgcgcc gaccagcgca agaagggcgt cgagtacgtg
     9601 aggggcctgc tggaagtgcc cggccgcaag tcgatccgga acatcgcgag cctgatcgga
     9661 ggccgggcga ccgaccagag cctgcatcac ttcatcagcg agtcgacctg ggactggacc
     9721 ccggtacgcc aggcactggc ccggtacctg gtgccccggc tgcccgtcga ggcctgggtg
     9781 gtgcacagca cggtgatccg caaggcggga cagcactccg tcggcgtgga ccgcagattc
     9841 gtcccggccg aggggcgggt gctcaacgcc cagcaggcgg tgggtgtgtg ggccgcctcc
     9901 gggcaccgga gcagcccggt ggactggggg ctgcatctgc cccaggcgtg gatcgacgac
     9961 cggtcgctgc gcagccgggc ctcgatcccg gacagcgccg aggtggagac gctgtccgac
    10021 cgggccgcga aactctgcgt cgacctggtg acggagtggg cgatgccggt gcggccggtg
    10081 gtgctggacg cctgctccct caacgcggcc aggctcttcg accgcctggg ccgcaagggt
    10141 gtccccctgc tggcgcgggt cgacccgtcc gtgccgctga tcgtcaacga cccggcgctg
    10201 accggccacc ggggctcggc gagcatgccg gccggcgagg tcatccgggc cgccagcggt
    10261 acccgacagc ccgtccgatg gcggccgggc ggccgcgggg ccggcatacg gtcggggctg
    10321 ctggcgagcg cggccgtgaa actccccccg gaaagaggcg ggcggctgcg atccggacac
    10381 ggcagacgcc ttgccctcat cgggctggcc gagggccggc agcaggacgc gccccagctg
    10441 tggctcacca gcctgacgga tcatcagccc gcttcgctgc tcacgctgtt caccctgctc
    10501 gaccgggtcg agtacgacta cttcgaggtc gccaagagcg tgggcatcga ggactacgtg
    10561 ggccgttcgt tcgacggatg gcaccggcac atgaccctcg cctcggccgc ccacgccgtc
    10621 gccgtgctct cctcgcccgg ccgggtgcgg aacacgccga cgtgcggggc gacggagccc
    10681 ggcacctgac gaagtgcgcc acggcgtgtt gttgccgtcc acccacgact ccaggatcgg
    10741 ggtgtcgggc cggtccgccc gacgcggcaa cccccacgtc gcgggagcgg gccggcccgg
    10801 cggacggccg aggcggcgtc gcccacagag ccggttgcgg caggggcgcc cgccgcgcga
    10861 cgccactgcc gcaacaggcc ccggtccgcc gggcgacggc cctcatcgac acaccgacgg
    10921 cagctcgtcc cgatcacacc gaggggcagt tcgccccgat cgcaccgatc cgcagctcct
    10981 tacgaccaca tcgcctcggc cgtcggggac gtacccacgc accggtccat ccggaatggg
    11041 agacatcagt ggacaaccct gtgctcgaca tcggctcgaa gccggcccgg cagcagccgg
    11101 ggtgggagga caaggagagt gttgggcggg tacggcggca gctgctggcc tcgccggggc
    11161 tcgtcgatcc cgaggacgtg cgcactctgc gctcggtgct gaccgtcgta gccgccggcc
    11221 gggcccatgt ggtgcaggcg ggcgactgcg cggaggaccc ggctcagtgc accgagggcc
    11281 atgtcgcccg caaggccggc ctgttggacg tactcgccgg tgaactcaag ggcatcacac
    11341 accggccggt ggtccgggcg gggcggatgg cggggcagtt cggcaagccg cgttcaaaac
    11401 cgaccgagtg ggtcggcgag ctcgaactgc ccgtctaccg cggccacatg gtcaacggcc
    11461 ccggacccga ccccctgagc aggcggccgg atccccgccg catgctggac tgctaccgcg
    11521 cctcccgtgc ggtgctgcgc cacctcggct ggcaccgcgc gcccggggtg cccggcatcg
    11581 atccgccggt gtggaccagc cacgaggcac tcgtgctgga ctacgaggtc ccgctggtgc
    11641 gccgcgacag caccggggcg ccggtcctca cctccacgca ctggccgtgg atcggcgacc
    11701 gcacccggca gctggacggc gcgcatgtcg ccctgctcgc cgcggtggcc aaccccgtcg
    11761 cctgcaaggt cggccccggt atgacggcga gcgagctgct ggcgctgtgc gaacgcctcg
    11821 accctgcgcg tgaacccggc cggctggccc tgatcgcccg gatgggtgcg cagctggtgg
    11881 cccaccgtct gccaccgctg gtggcggcgg tacgggaggc ggggcatccc gtcatctggc
    11941 tctgcgatcc gatgcacggc aacacggtca cggcccccga cgggcgcaag acccggtacc
    12001 tcgactggat cgtgcgggag gtacgggact tccggtccgc cgtcctcacc gcccgcgggg
    12061 tcgccggtgg cctgcacctg gagaccaccc cggaccaggt ggccgagtgc gccaccgacc
    12121 cgtccgccgc cgacctggac cgcggcacct acaccagcct gtgcgacccg cggctgcgcc
    12181 cggaccaggc cgtggccgcg gtctcggcgt gggggacgta gcggcctcga gggccgacac
    12241 cgtcgctgtc acctcagctg tcacctcata cgaaggagga ctccacatgg agggcaaggt
    12301 cgccctgatc acgggagcgg caggagggat cggcgccgcg gtggcgcgcg cgctcggtga
    12361 gcgcggcgtc acggtggccg cggtcgaccg ggacgcggac gggctgctgc acacggtgca
    12421 gaagctgacc gccgacggcg tgagtgcccg ggcgttcccg gccgacatca ccggtcgcgc
    12481 cgaggtcgac gctctggtcg acaccgtcga acagcagctg ggcccactgg acttcctggt
    12541 caacgcggcg ggcgtgctgc acctgggcga ggcccggcat ctcaccgacc aggactggga
    12601 cgccacgttc gcggtgaacg ccacgggcgt gttcgtggtg tcgcgcgcgg tcgtcaaccg
    12661 gatggtgccg cgccggcgcg gggccatcgt caccgtggcg tcgaacgcgg ccggcaccgc
    12721 ccgcacgcag atggccgcct acgccgcgtc gaaggccgcc gccacgatgt tcaccaagtg
    12781 cctcggcctg gaggtggccg ggcacggcat ccgctgcaat ctggtggccc ccggttccac
    12841 cgacacaccg atgctcagct ccatgtggcg ggacaacagc ggtcggcgga ccacgatcgc
    12901 cggccggccg gaggagtacc gcgtcggtat cccgctcggc aagctcgcca tgccctcgga
    12961 cgtcgccgac gccgtggcct tcctgctgtc cgaccgggcc gcccacatca ccctgcacag
    13021 cctcacggtg gacggcggcg ccaccctcgg cgggtagccc gccggaccgg acgaggcgga
    13081 gagaggacca tgaccgggaa gatcaccacc gggacgaccc cggccgggag gaccaccggg
    13141 atacctccca tcgaacccta cgagctgccc agcgcgcgcg agctgcccga ccccgtcccg
    13201 ccctggcggg tcgaccccgg ccgcgcggtt ctcctggtgc acgacatgca gcactacttc
    13261 ctccggacgc tgccggaacc cctgcgcgaa cagctgctgc gcaacgccgt gctgctgcgg
    13321 acacgctgcg ccgccctcgg catgcccgtc gcgtacaccg cgcagccggg cgccatggac
    13381 gatgcggagc gcgggctgct gaaggacttc tgggggccgg gcatgcaacg ctcccccgcc
    13441 gaccgcgaga tcacggcgga actggctccc accggccggg actggatgtt caccaagtgg
    13501 cgctacagcg cgttcttccg ctccggtctg ctggagcgga tgcgggcgca ccaccgcgac
    13561 cagttggtcc tgtgcggggt gtacgcccat gtgggcgtgc tgatgacggc ggtcgacgcg
    13621 ttcagcaacg acatcgagac gttcctggtg gccgacgcgg tcgccgactt ctccgccgcc
    13681 caccaccggc aggcgctcga ctacgcggcg cgctgctgcg ccgtcgtctc cacggccaag
    13741 gaggtcatcg cgtgacgtcc gatctgctcg gcagggtgct ggtggcgcag cccccgccct
    13801 tcgccctgct ccaccggtcc accgcggccg gcggcggacg cctggacgtc ctcgtcggcg
    13861 aggtgcacac ctggccgacg ctcgacgcga ttgcgctgcc ggagccgtcc gccgccggcc
    13921 cggcccgtca tgacgtcctc gcgctcgtgc cgtaccggca ggtccgcgag cgcggtttcg
    13981 ccgcggtcga cgacggcgcc ccgctgctca ccctgcaggt gaccgaccag gacacggtgt
    14041 cggcggctga ggcgccggcc cgcctggacc gggtgccgac gccgttgctg gacgggcgtt
    14101 tcacgcccga cgacgagacg tacgccgcca ccgtgcgcga ggtcatcgag cgggagatcg
    14161 gcatgggcga gggcgccaac ttcgtcatcc gccgctcgta ccgggcccgg atcggtgact
    14221 acagcctggg cagcgcgctg tcgttcttcc gcaacctgct gcagaccgag tccggcgcgt
    14281 actggacgta tctggtgcac accggcaccc gcacgttcgt cggcgcctcg ccggagcggc
    14341 atgtgagcct gtccggcggt acggcggtga tgaacccgat cagcgggacg taccgctatc
    14401 cgccctccgg gccacggctg tcggaactgc tggacttcct cgccgaccgt aaagagaccg
    14461 acgagctgta catggtgctg gacgaggagc tgaagatgat ggcccgcgtc tgcgaggacg
    14521 ggggccgggt ggtggggccg tatctcaagg agatggcccg gctggcgcac accgagtacc
    14581 tcatcgaggg gcgcagcacc cgtgacccgc gggagatcct gcgcgagacg ctgctcgcgc
    14641 ccacggtcac cgggagcccg ctggagagtg cgtgccgggt gatcgagcgg tacgagcccg
    14701 agggccgcgg ctactacagc ggcgtcgccg cactgatcgg ccgggacgcc gagggcgggc
    14761 gcacactgga ctcggcgatc ctcatccgca ccgcggagat cgacagcgcg ggccggctgg
    14821 agatcggcgt cggagccacc gtcgtacggc actccgatcc ggtgtccgag gccgcggaga
    14881 ccagggcgaa ggccgccggg ctgctcgcgg cgctggaaga cgggcggccg gaccgcttcg
    14941 ccgaccatcc gagcgtgcgc acggcactgg ccgaacgcaa cacctccgtg gccgacttct
    15001 ggctcgccga ccgcggcaca ccaccgccgc ggacgccggc gccggccggg acgagcgtgc
    15061 tggtcgtcga cgccgaggac acgttcacgg cgatgctcga ccaccaactg cgctcgctcg
    15121 ggctggcggt gacggtacgc cggtacgacg agagttacgc cctcggcgac catgacctcg
    15181 tggtgctcgg ccccggcccc ggcgaccccc gggacgccgg gcatccgaag gtggcgcggc
    15241 tgcgtacggt cgtcgacacg ctgctggccg ggcaccggcc gttcctcgcc gtgtgcttca
    15301 gtcaccaggt gctgtgcacc cggctggggt tcgaactggt ccgcagggac gtgcccaacc
    15361 agggaacgcg acgggagatc gacctgttcg gggcgcgtga gagcgtcggc ttctacaaca
    15421 cgttcgccgc gcgggcggcc gaggacaagg tggagtgcga gggcgtgggc acggtggagg
    15481 tgagccggga ccgggagacc ggtgaggtgc acgcgctgcg cgggccgcac ttcgcgtccg
    15541 tgcagttcca cgccgagtcg gtgctgacgc gggagggtgt gcggatcctc gcggaactgc
    15601 tgggcaacct ggtctgagcg ggacacacgg gggcggctgt gcgaggggct ccggcccacc
    15661 gcacagccgc ccctgttgct tatcggctac ggccgcccag cgcacggtcg acgagcggcc
    15721 cggcggcacc ggtgtagccg acgggatcgc acaggtcggc caactcttcg gcgtcgaggc
    15781 cgatttcagg catcgccccg aggatctccg ccagggcggc cccgctctcc tcggccttcc
    15841 gggacgcctc gtcgagcagt ttcctggcgg ctgcgcctcc caggcgaggt gcgagtacgg
    15901 cggcgatccg ctcggcgacc acccgggagc cggtcaactc caggttctcc cgcatccgtt
    15961 cgggccgcac ctgcagtcct tcggcgagtt gtacggcggt gtgggcggcg ccgccggcca
    16021 ggcgcaggca ttcgcgcagc agctgccact ccgcatgcca gccgcccgcc gaccgctcgt
    16081 cctcggacac caggcactgg gtgagcccgg cggcgatcgg cgggacctgg atcgccgcgc
    16141 tgcgcaccag cgtggccagg accgggttgc gcttgtgcgg catcgccgac gacctgcccc
    16201 ggccgggccc ggcgggttcg gcgacctcac cgacctcggt gcgcaccagc gactgcacat
    16261 ccaccgcgat cttccccaac gcccctgccg tgaacgccag cgccgcggcg agatcggcca
    16321 tcggcgtacg cacggcatgc cacggaagca ccggccgggc cagcccggtc tcctcggcga
    16381 acgcggtgat gagccggtcc gggtaggcgt cgaggtcggg cccggtgagt gcggtcgagg
    16441 cgagatagcc ggccagggtg cccgccgctc ccccgagaga cacgggcagc tgaccggcca
    16501 ccgtgcgcag tcggtggccg gcggccagga cgagttcccg ccagcctgcg gccttcaggc
    16561 cgaaggtcgt cggtaccgcg tgcagggcca gtgtccggcc cgccatcggg gtgtcccggt
    16621 gctcggccgc caggcgggcc agtgcgtcgg cggtggtgtc caggtccgcc aggacgatcc
    16681 ccagggcgcg ccgcgcgatc agcatggcgc cggtgtcgaa gacgtcctgg ctggtggagc
    16741 cgcggtgcac gtactccgcc gccgccgggg accgggaccg taccgccgcg gtgagcgccg
    16801 ccaccaggcc caccaccggg ttggcggtct cccgggccgc gaccgcgagg gctcgcaggt
    16861 cgagccggtc ggcgcgggcg gcgcgggtga tcgcctcggc cgcctccggt gggaccgtgc
    16921 cgagccgggc ctgggcccgg gccagcgcgg cctcggcgtc cagcatggcc tgcagccagg
    16981 ccaggtcgca cacggccgcc tcgacgggag tgcccgcccg caccggcgac agcagccccg
    17041 cgtcgatgag ggtgtcgttc atacgaccac ctccgtgagc cgcgtccctc cgaggccctg
    17101 ccgggccggc gacagggtca gcaccgcacg ggcgatggcg tccgcgtcgg ccagcgtcac
    17161 ggagtccacg ccgggacgga cgccggccgc ggtcacccag tgcaccgact cggtcgggac
    17221 accgtaggcg aaccggcgcg ggtgggggcg gccctgcccg tcgatgaccc ggcagggccg
    17281 ctcggtgacg gcgagtccgc cggtctcgtg gctgacgccg cagtcccctt cgatgcgatg
    17341 gggccggcac tgctcggtca ggagcaggtg gcgcagcagc ggatcggcgg tgcgacgcag
    17401 gtcgggcggg ggcaggcggg cctcgatgag atgcgcggag cgcaccgggg ggccgggcac
    17461 gagggtcgag tgggcgacga aggcggggcg ttcggtgtcg acgcggatct gggtgccggg
    17521 gccggtgagt tcgaggatgc ccgcctcgat cagcgcgatc atctcctcga tgcgggagac
    17581 cggcggcccg atggacagga acgcgttgag cggtgtgtac cagccctcca gctcgtcgag
    17641 gtgcgagccg ccttcgagtc ccgagtggtc gaccaccagg cgtacctcgt tgcgcaggtc
    17701 gcgcaggacg tccagcgccg ccttgagcgg accgctgaca ttgcccgcct tcgcctcccg
    17761 cacgtcccgg gccaggtact ccagcagcca gccgcggaac tccgcccggc cggcgaaggc
    17821 gcgcccgtgg cagggccggg cgagccggtc ccagtcccag cggtcggcgg ggccgatgcc
    17881 gtgctcgtcc aggagggccg gccgctggcg gggcgaggcg gtgaggtagc ggcgtacgaa
    17941 cggctcggac gcggcgttgc gggcggcgag cagtgtgccg tagtagacgc cttccacctc
    18001 cgcggcgatc agcggccaca cgtcggacag gaagcgcgcc cgctcgccgc ctcgggcgcg
    18061 cccgcgcagg gcggcgatgg tctccggggt gagcagccga ggggtgtgcc tgccgaacgc
    18121 gcccttctcg ttctcgccgc gcgcgtgata cggcactccg cggcgcgagc tggcacagag
    18181 ccgtggctcg cggccggacg ggcggtagac caggcggtct ccgagccggt cgaagacgcc
    18241 gccgcggccg gtggtgaaca gcgccatgtg gtcgaagaag ttcaggccga ggccgcgcag
    18301 cagcaccggc tcgccggcct cggcgaagga ggtgtccacg tcggccgggt tggccggcgg
    18361 aacgtaggtg aggtggtgga tgcgggccag gctggccgtc cgttcctgac ggggggtcag
    18421 ctgggtcggg aggtgcccca gggccagcac cacggcgtcc agttcgtgga tcctggtgcc
    18481 gtccgccagc cgtacgccct gcgggccgcc gggcgtgccg tgggtgtccg ccatcgcgac
    18541 ggcgcgtgag cggtgcacct cgacggtgac gtgctccggg gcgcgggcga cgatctggcg
    18601 gaagcagtcc cgcaggtact gcccgtagaa ggcgcgggtg ggataggagt ccggccgcag
    18661 ggtccgggcc tcggcgagga cggcctcgtc gtaaccgccg agttccccga agcgggccag
    18721 gctgtccgcc cactcgtaca ggctgggccc cggctcgacc ggtccctcga tgcgggattc
    18781 ggcgtcggtg aacacggtga tctggcaggc cacggtgttg gtgagcagtt gccgggactg
    18841 gtcggtgcgc cagacggcac cggcgcccgg ggcggccggg tcgacgacgt gcacggtgac
    18901 ggagcggtgg gaccgggccg tacgttcgcc cgcgcacagc cgttccagca cgcacaggcc
    18961 gcgcgggccg gcgccgacga tgcacacccg aagccggccg gcgctcatcg gcgggctccg
    19021 tcggcgccga actcccgtgc tccgtgcatc caggccacat ggtcgtgcag ggccggtccg
    19081 gacagggccg acagcatctc gttcctcgct ttcgcctcgg cgccggccgg gtgccacagc
    19141 cgggtgctgg cccgggcggc gtgggtgatc cgggcggtgc gctcgcgtcg ttcggcgttg
    19201 tacttctcga accggtcggg gatcgtgtcc gccccgtcgt ccagcaggcc ggccagcacc
    19261 acggcgtcct ccagggcctg gcaggcgccc tgggcggcgt agtgcagcat ggggtgggcc
    19321 gcgtcgccga gcagggtcac ccggccgtcg gtccagcggt cgaccgggtc ccggtcgacc
    19381 agggcccatg acttccagtg ctcacccagg gcgagcagcc gctgtgccgt cccgccgagt
    19441 gcggccaact cgccgagcac ccgggcctgt tcgacgggga ctgcggcgaa cgcctcggtg
    19501 gcgccgttct ccacgctggg ggcgaggttg agataccggc cgccgccgat cgcgtagtgc
    19561 acgaagtggc agcccggtcc ggcccaccag gtcaccgcgt tccggcgcag ctcctcgggg
    19621 acccgttcca tcgggatcac cgtgcggtag acggtgatgc cggccacccg cggcgcgccg
    19681 tcgccgacca gccggcgccg gatcgccgag tggatgccgt cggcgccgat caccgcgtca
    19741 ccggtgaccc gcccgccgcc gtccagcagc accgtggcag cggagccgtc ctggcggtat
    19801 ccggtggcgc gactgccggc gcgcagttcg atcgccggtg agcggcggca ggcgtccagg
    19861 agcagccggt acagctcgcc gcggtggacc acgacgtacg gattgccgaa ccggcgccgg
    19921 tagccgccgg tgagcggcat gctcgccacg tgctcgccgg tcacgccgtc catgaaccgc
    19981 agttcgtcga tgtgcaccgc cagcgcgcgc acggcgtcgc cgaggcccag gcggtccagg
    20041 gcgtgcagcc cgttgggtgc cagctggatg cccgcgccga tctcggcgaa ctcctcggcc
    20101 cgttccagta cgaccgcccg gtgtccgcgc cgggcgacgg cgacggccgc cgccagcccg
    20161 ccgatgccgc ccccgacgac gaccatcctc gccatgccgc cccctaccgg ccctggccgg
    20221 cggctgccag cagctgcgcc agctggagcc gcttgatctt cgtggtcgcg gtctgcggca
    20281 ggtccgacag ccgccactgc accgggtccg ccatcgcggg cagcccggcc gtggcctgcc
    20341 gccatgcctc ccggtccagg gggctgtcgt ccttggtgca caccacgggt acggcggtgc
    20401 cgtccgcgcc ggggatgatg atcacttcgg cgagttcgtc cagcttggcg aagagggtgt
    20461 cctcggcggc gagcgtgctg ccgaacccgg ggatcaggtc gacctcacgg tccagcaggt
    20521 gcaggcaccc ccacttcgac ctgaagccga cgtcgcccat ccgccaccag ccgtcgtcga
    20581 gctgccgggc gtagcgttcc gcctcgccca ggtaggtggt gatccggccg tcgctgcgca
    20641 cctcgatgta gccggggttc tcctccgagg gcggccggcc gtcgcggctg accacgcgga
    20701 cgtcggtcat accggggaag ggcatgccga cgcagcgccc gtcggcgtcg ggggcgtgcc
    20761 gccgggtgaa ggcccgcacc accgtcgggc ccacctcgct ctgtccgtag agctgtccga
    20821 acaggggtgc cctgcggcgt gaggcgcgca gcagccggtg cacggtgcgc gggtggatgg
    20881 cgtcgaacgt actgctgaac agcttgacgt tggccagcgg tgcgcggtgg tcgtcggcca
    20941 gcttctccca gcgcagatac gagttggggt gcgcctcgag gatgccgggg cggacacggg
    21001 cgaacaggtc ggcggcgcgg tccgggtcct cgtcggccag caccacgatc gggagaccgt
    21061 tcaacaggga gatggccagg gcggtgaaca gccgcgagtg cacgaacgac acgtgcatgg
    21121 caacggtttc ccgcctgcgg atgacggggg tgatcgccag tcgctgcggg cggtagcggg
    21181 cctgcagggt gcggcccgtg tgcaccgcca gcttgggcac cccggtggtc ccggaggtgt
    21241 gcgtgatcag cgtcgggtgg tcggcgggca tggtcaccgg ggtgacgcgc cggacgccgg
    21301 cgaagtcctc cagctcgacg gcgcgggcat gggtgccgga ggtgagcagg acgctctcgg
    21361 cgaggtcgaa gacctccgcg ggcagctcgt cgtcgagctt ggcctggtcg gtgacgagat
    21421 gggggcggtc cgcacgccgg accagttcgg ccacggtgtc accgtcgaga tggggcgaca
    21481 gcagcaccgg caccgcgccg atccggctga tcgcgcaggc gagcaggggg atgtcgaagg
    21541 tgtcggactt gtggacgacg acgcgttcac cggggcggat cttcgccgcc cacagccgcg
    21601 aggccacgtc cgccaccagg tccgccagct ccgccacggt cgcccggcgg ccgaggtcgg
    21661 gggccaggtc caggtcgtgg tcgaggatga gcacgttcgc ggggtgccgg gacgccgcgc
    21721 gctcgaagag cgtccccagc cggattccac ggtttcctat gcgctgcagc agcatctgtc
    21781 cgccttccgc cggtcgctgc ggagagtcag gggtcggttc gggaggtcgt gcacggggta
    21841 cggctgagcg gggtcaggtc cgctcgacgg cctgcttgat gcggtgcacg gtcgctgcga
    21901 ggtcggccgt gagcttggcc gtccagtcgc tgaagaaccg ctgcttctcg tgcgcggcca
    21961 tgtccgcggt gatgccgcgg atgccctccg tgggcgcgcc catccagaag ctgtgcacca
    22021 ggacgcagcc gtcgtccgcg gccctgaggt cgaacgacca gacgctctcc tgccgccgtc
    22081 cggaactgtc ccggatcgcc cagcggaagc tgcggcccgg ctcggcggcg acgacctcgg
    22141 agtcggtggt ccatgcgccg cggacgacgg gcgcccaggc gaccacgtcg gcggggcggt
    22201 ggttctcgcc ccggaagacc gcgcccacgg ctgcgggggt tccctcgacc cactggccgc
    22261 cggtgcactc gacgctccac tccccgctcc gcggcaggtc gctgaccgtg gcgtacacct
    22321 cgtccgcgga cgcacgcaca tgggtttcgg cgctgacctg gaagagcgcg gtggtctcga
    22381 ggttctcgag gttcttggag tccttgaagt tctcgagttc ggtatccgtc atggccggaa
    22441 gcctcgccag tggcacggaa cccggtcaac gcacgccgac cgggtccgtc aagtcgcctc
    22501 gggcgttcag gagtcgaggt ccggacgcag cacgagacgt ctgccgcgca gttcgccccg
    22561 ttccagccgg gcatgggcct cggcggccgc gctcagcggt gcctcctcga ccgcccgggc
    22621 gcgcagactc ccccgggcca gcagccggtt cacggagcgg gcgacgtcgg cgagttcggc
    22681 ggtcgtggcg tgcgagatgg cgaagccggt gaccgtggcg tccttgaggt acagcggccc
    22741 gaccgggagg acggggcgtg cgcgcaggcc ggcgagcacc acgatccggc cgcggaaggc
    22801 gaggaggtcg accgcggccg gcaggtcgtt ccagccggcg gcatcgacga ggagatcgat
    22861 gccgtccggc gccaggtccc gtagccgctg cgggagttcc gggtcgcggt agtccgcgca
    22921 ggcctgggca ccgagcgtcc ggcagtactc cgcgtcgccg gcaccggcgg tcgcgatcac
    22981 ccgggcgccg gcctcggcgg cgagtaccac ggcggcgctg cccacgtttc cggcggctcc
    23041 cgcgacgagg actctctcgc cggcgcggag cccgccgtgg gcgaacaggg caaggtgggc
    23101 cgtggctgcc ggatgcagca cggctgccgc gtccgtcggc ggcaccgcgt ccggcagacg
    23161 gtagaggcgg tcgaccggca ccagcgcctg ctgagccgcc gcgccctgcc gtccggcgtg
    23221 gccgaggctg ttgcaccaca ccgtgtcccc gaccgcgaag ccggccacgc cgtcgccgac
    23281 ggcggcgacc gtgccgacca ggtcacggcc gatgacgaac gggaaggtca ccggggtccg
    23341 ccaggccccg gagcggacga acgtgtcaac cgggttgacc ggcgtggcga ggacgtcgac
    23401 cagcacgtcc gtcggccctc ctcggggcgg ggggaggtcg ccgacgcgaa tggcgtccgc
    23461 cgggccgagt cgctcgatgt aggcagcctt catgggccgc atg
//
