LOCUS       BGC0001851             43900 bp    DNA     linear   CON 24-MAR-2023
DEFINITION  Streptomyces erythrochromogenes strain NRRL B-2112 contig4.1, whole
            genome shotgun sequence.
ACCESSION   BGC0001851
VERSION     BGC0001851
KEYWORDS    .
SOURCE      Streptomyces erythrochromogenes
  ORGANISM  Streptomyces erythrochromogenes
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            JNZG01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:25:35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 186423
            Orig. end    :: 230323
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1014)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 249.7; E-value: 8.1e-76)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346928.1"
                     /locus_tag="IO28_RS0104710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_245240007.1"
                     /transl_table=11
                     /translation="MSPVPTGRDGDGGRRVRMGVLGCADIALRRMLPAIAAAESAELVA
                     VASRDAAKAQRAAARFGCAGVKGYRTLLERDDIDAVYVPLPPALHFEQVAEALLAGKHV
                     LCEKPLCTTHAEAAELMELARRHRRILAENFMFLHHSQHAGVRSLVESGAIGGLEVLSG
                     SFGVPPLDPTGFRYAPSLGGGALLDVGVYPLRTAQMYLSGEPEVLAATLRVDDATGVDV
                     AGTALLCAPDGVAAQLEFGFRHSYRSRYALWGGAGRISVERAYTPPEVLKPVVRLQQQD
                     RLTELAMPADDQVRNALAAFTAAVLAGGDGPVGEAESLLQARLVEDVRKVARIVGG"
     subregion       1..43900
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..43900
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1014)
                     /locus_tag="IO28_RS0104710"
     gene            complement(1011..2120)
                     /locus_tag="IO28_RS0104715"
     CDS             complement(1011..2120)
                     /EC_number="2.6.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     392.5; E-value: 3.3e-119)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963467.1"
                     /locus_tag="IO28_RS0104715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_031146979.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.4e-120,
                     bitscore: 393.4, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTYVWDYLREYENEREDIHDAVETVLRSGQLVLGASGRGFEEEF
                     AAYHGVGHAVGVDNGTNAIKLGLQAIGVGPGDEVITVSNTAAPTVVAIDSVGATPVFVD
                     VHPDTYLMDVEQVSAAVTERTRCLLPVHLYGQCVDMTALQAVADEHGLVVFEDCAQAHG
                     ARRGGRLAGTWGAAAGFSFYPTKVLGAYGDGGAVITSDPAVDAALRRLRYYGMEERYYV
                     VQTPGHNSRLDELHAEILRRKLRRLDAYVEGRRAVARRYAEGLAGTGLVLPSTAPGNDH
                     VHYVYVVRHPRRDAIIEALKAYDIQLNISYPWPVHTMTGFAHLGYAKGSLPVTESAAEE
                     IFSLPMYPSLDPAVQDKVIGALHDVLASL"
     gene            complement(2170..2880)
                     /locus_tag="IO28_RS0104720"
     CDS             complement(2170..2880)
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 195.5; E-value:
                     1.8e-59)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346926.1"
                     /locus_tag="IO28_RS0104720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_031146981.1"
                     /transl_table=11
                     /translation="MYGQELAEVYEIFYRSRGKDWPAEAAHVTDLVRARCPEADSLLDV
                     ACGTGAHLETFGTLFKHTEGLEIAAPMRELAHRRLPAVTVHPGDMRAFGLGRTFDAVVC
                     MFCAIGYLGTVADMRDAVRSMARHVRPGGVLVIEPWWFPENHVEGYVAGDLGRENGRTV
                     ARISHSTLQGRATRMEVRFLVGDSSGIREFTEVDVLTLFTKDEYLAAFADAGCTVEYLP
                     GDPTGRGLFVGVRQ"
     gene            complement(2920..3699)
                     /locus_tag="IO28_RS0104725"
     CDS             complement(2920..3699)
                     /EC_number="3.5.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891736.1"
                     /locus_tag="IO28_RS0104725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclase family protein"
                     /protein_id="WP_031146983.1"
                     /transl_table=11
                     /translation="MRLIDLSSAVDATAYEPDPVVHEVLTPRQGAEHMSAEMRTHFGLE
                     FSPEELPDGEFLSLDRITLTSHTGTHVDAPSHYGSRAGYGDGVPRHIDRMPLDWFCRPG
                     IVLDLTDAATGVVGAARLEKEFERIGRTPAPMDIVLLRTGASARAGTPEYFTEFAGLDG
                     PAVHLLLDLGVRVIGTDAFSLDAPFTDIIERYRRTGDRSVLWPAHFAGRDREYCQIERL
                     ANLDALPAPYGFTVVCFPVKIAGAGAGWTRAVAMVDE"
     gene            3888..4325
                     /locus_tag="IO28_RS0104730"
     CDS             3888..4325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346924.1"
                     /locus_tag="IO28_RS0104730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_031146985.1"
                     /transl_table=11
                     /translation="MRTGTSSSFDSLYAEVQQFYADHMHLLDAGDGEGWARTFTEDGSF
                     APPSLPEPVVGRAALAEGVDKAAAALAEAGEVHRHLLGMVSVRPGEDGSLSVRSYAQII
                     ATARGGSPRLHLMCVCDDVLVRVDGELKVRERRVTRDDRRP"
     gene            4384..5331
                     /locus_tag="IO28_RS0104735"
     CDS             4384..5331
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     170.3; E-value: 1.1e-51)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346923.1"
                     /locus_tag="IO28_RS0104735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_245240009.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.5e-17, bitscore:
                     54.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTAEEVGRATGRRTVAVLGATGTIGRQVAAAFTRAGHEVLGVAR
                     HPAPHTARHPFVPLDVAEADPRDIADLLAERNVDVVVNATGGWVVTEEAMHHAHVRLVE
                     RMLAGVAKLPTRPRVVHVGSIHEYGFVSPDPDGIDESVPPEPTTPYARTKLAGSQAVLE
                     AARTGDVDGVVLRPVNVCGPHPSEASFLGTVLNRLRALTPGERLELVIADAARDYVDVR
                     DVASAVLVAADAAASGTVFNIGRGEAPTMRELVTTLVEAAGFPPGTVKETGGAVESKGG
                     GWTKADIRRAERVLGWRPAIGLRASLHDMWKAAG"
     gene            5402..5659
                     /locus_tag="IO28_RS0104740"
     CDS             5402..5659
                     /NRPS_PKS="Domain: PP-binding (10-74). E-value: 7.4e-07.
                     Score: 21.5. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104740_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 81.6; E-value:
                     5.5e-25)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330942.1"
                     /locus_tag="IO28_RS0104740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_031146990.1"
                     /sec_met_domain="PP-binding (E-value: 5.5e-07, bitscore:
                     21.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELTLPVLVEIFRECAGEADGADLDGEDVGDVELNVLGYDSLAL
                     LEAISQVERRYSIGMPDAETRIKTLNQFLEQANEQLVQRS"
     aSDomain        5432..5623
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104740_PP-binding.1"
                     /evalue="7.40E-07"
                     /label="IO28_RS0104740_PP-binding.1"
                     /locus_tag="IO28_RS0104740"
                     /protein_end="74"
                     /protein_start="10"
                     /score="21.5"
                     /tool="antismash"
                     /translation="EIFRECAGEADGADLDGEDVGDVELNVLGYDSLALLEAISQVERR
                     YSIGMPDAETRIKTLNQFL"
     gene            complement(5683..6402)
                     /locus_tag="IO28_RS0104745"
     CDS             complement(5683..6402)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 218.8; E-value:
                     1.3e-66)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346921.1"
                     /locus_tag="IO28_RS0104745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_031146991.1"
                     /transl_table=11
                     /translation="MYGAELAEIYELIHRSRGKDYLEEAAEVERQVRAHKPDAASLLDV
                     ACGTGAHLRRFDELFDEVAGLELSEPMARFAQAALPHVPVHVGDMRDFELGRTYDVITC
                     MFGSIGYLLTQDALVGALRRFARHLAPDGVLAVDPWWFPETYLHGHVAGATATVGGRTV
                     SRVSHSVREGDASRMNVHYLVADGASGVRHFHETHLIGLFSRERYEAAFGAAGFRVDYV
                     PVAPAGRGLFVGVPSAG"
     gene            6638..7834
                     /locus_tag="IO28_RS0104750"
     CDS             6638..7834
                     /EC_number="1.14.13.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346920.1"
                     /locus_tag="IO28_RS0104750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_051892704.1"
                     /transl_table=11
                     /translation="MSTGTSTDRTADARAGSPSAEVAELLDVLRGYLDLAPQLSLPPRA
                     FTSPELYELERTRVFGRSWVLVAHRDELAEPNSYVSVDIAGEQILVTRDADGALHGMSP
                     ICRHRMMPLVEPGATGRADSFTCPYHLWRYGLDGRLIGATHMRRNPDFDPKDCRLPAFA
                     VEEWHGFVYVNLDAAAAPLAPELKRISGDLTNYRLDEMAQLGSWSEEWACNWKVAVENA
                     HENYHVMGFHPETLQQSTPGGSDTDVRVDSPWALRLLVPFTEPQEAYALPLTDTEKAHL
                     YGIFVFPAASLAAAGEMVIWLSLIPQTIDRTLVRGGILVPRAALEGADLDEMRRQAETY
                     AGMINSEDRNGLEAVQRAVGSRFAARGHLSPKEPGVVAFYQNLARALLRADDDWPGGL"
     gene            7921..9138
                     /locus_tag="IO28_RS0104755"
     CDS             7921..9138
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487468.1"
                     /locus_tag="IO28_RS0104755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_031146993.1"
                     /transl_table=11
                     /translation="MLSCRICGGRLHEFIDFGQQPLSSGLLEPEYLGDEFFFRLAVGVC
                     GDCTMVQLTEEVPRHLMFNSHYPYLSSGSSVMRGHFEETARHFLATELTGKDAFLVELG
                     CNDGVMLRALAEAGVRHLGVEPSQSVADIARRQGIRVATEFFQESTAADIRKEEGHAQV
                     IFAANTICHIPYLDSIFRGVDELLAPDGVFVFEDPYLADIVDLASFDQIYDEHYYFFSV
                     SSVSAMVERFGFELVDVERLSVHGGEVRYTIARAGRRTPAPAVAELLGQERARGLSELA
                     TLQGFVARVERARDELVALLRRLRDEGRTVVGYGATAKSATVANYCGIGPDLISFISDT
                     TPNKQGRLTPGSHIPVRSRADFENPYPDYALLFAWNHAEEIIAKEQQFRASGGKWIRYV
                     PDVRVL"
     gene            9190..10563
                     /locus_tag="IO28_RS0104760"
     CDS             9190..10563
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 380.1;
                     E-value: 2.5e-115)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346918.1"
                     /locus_tag="IO28_RS0104760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="activator-dependent family glycosyltransferase"
                     /protein_id="WP_031146995.1"
                     /sec_met_domain="MGT (E-value: 7.4e-143, bitscore: 467.8,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFTTHTAKSHLFAQVSLAWALRAAGHEVHMAGQPDLADDITR
                     TGLTAVTAGAALDLAAQMESYEHDEHDGSGDGTVQDPGAWEGTGGADDYRAIAERYEYW
                     TDMTEIRPQKLSYEYMHGVFTAMTTQVFQQYSAPAMIDDLVRHARWWRPDLVVWDPLTF
                     AGPVAARAVGAAHVRLLFGLDLIGRMRRPYLDALRRLPPAQREDPMEEWLGDTVRRYGG
                     EFGEDLVVGQRTIDPLPPALRFLDGPDRVPMRCAPHNGSSVLPDWLREPQERRRVCLTL
                     GVSHRELLGADRLPLGEVLAALAGVDAEVVATLNAAQLASVTEVPDNVRVVDFVPLETL
                     LPSCSAVIHHGGAGTFNTALSCGVPQLILPDGVWDTDHKARLLEERGAGIRVAQPEKAD
                     AATLHGMITRLLEEPSFGRAAARLRDESRDMPAPSAVVPVLEELAAGRRPHQRQGEWQ"
     gene            10560..12179
                     /locus_tag="IO28_RS0104765"
     CDS             10560..12179
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]; GO:0016491 - oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 443.3;
                     E-value: 2.5e-134)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346917.1"
                     /locus_tag="IO28_RS0104765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding protein"
                     /protein_id="WP_031146996.1"
                     /transl_table=11
                     /translation="MKDLSRRGFIAGGVAAGGAAALTAAGTGTAAADTTAAGCFPAPPA
                     KDIRPGDPRYAELTARGYNGRFSGRPESVRLVHRADQVVAAVDDALRTGRRIAVRSGGH
                     CFEGFVDDPAVQVVVDVSEMKSVHYDPRHKAFAIESGATLGEVYRTLYLGWGVTVPAGA
                     CPGVGAGGHIAGGGYGGLSRHHGFVADHLYGVEVVVADRPGRARLVTATRDPADPHHDL
                     WWAHTGGGGGNFGVVTRYLMRSPGARGDDPTTLLPKPPATIRSVTIGWSWADMTEAAFV
                     RILRNHGTWHERESAADSRYAPLSAWLILNHRANGRFTLVANVDGSLPHGAQLLDEYVA
                     AITAGTGVRHEAEQATALWMKSTLTTDPYAGGGYPFKSKAALLRKAWTETQIRTLHRCL
                     TSSGGEHQGSAVYLSTLGGRINTVPASATAIPHRDSLFSASYETSWWPGISGDEQLAWV
                     RELYRDLYADTGGVPVPDAANGGAYINYPDVDLADPRWNTSGVPWHTFYYRDNYPRLQQ
                     VKARWDPADVFRHALSVRPPGR"
     gene            complement(12219..13337)
                     /locus_tag="IO28_RS0104770"
     CDS             complement(12219..13337)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 252.5;
                     E-value: 1.4e-76)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346916.1"
                     /locus_tag="IO28_RS0104770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1205 domain-containing protein"
                     /protein_id="WP_031146998.1"
                     /sec_met_domain="MGT (E-value: 4.9e-104, bitscore: 340.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFVNSPGLGHIFPSVPLAHALTAAGHDVLFAQGGDVGAVAAA
                     GVNVVDVTPGLDYATVFRPEEIDFSVDGGDEFVAALFARVSGVTVDRLLEVARGWSPDL
                     IVHSPLQGAGPLVAGALGVPAVSVVTGPADSAPLIAGLMRDHMKEHYVRHDVAPVPAPG
                     FRLNSIPPSLLELLPERVRAEDDVPFRYVPFNGNGELPGWLLEPPRRPRIAVTLGSIAG
                     LWGGLAVLAPLVASAAGTDAEFVVTLGGGDPSLLGELPPNVRTVDWLALGPLLRTCHGL
                     IHHGGSGTSAVAMAMGVPQCVMPLSPDQKDNERAVVERGIAIGTSAGVVGTAEFRALLE
                     DEGMRAAAAEVRDEAAAMPSPAALVGRLESLV"
     gene            13498..14268
                     /locus_tag="IO28_RS0104775"
     CDS             13498..14268
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 70.7;
                     E-value: 2.4e-21)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346915.1"
                     /locus_tag="IO28_RS0104775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_031147000.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.8e-08, bitscore:
                     25.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIGNGFLARHLAPLSAGHPGVTVLAAGVPTHPLPDAEHRREAA
                     LVEDAIRHCLRRDRMLVFFSTVSMYGGPGGPGDEDGPQVASTRYGQHKLDLERLVKASG
                     VRHLVLRLGYVLGPDEPGFRLLTALVTQVLAGRVRVQRGARRDMIHVADFTTVVDALLR
                     TGVCDETVNVASGDCVEVADVVRHLEQRLGVTAHWQVTDDSIEHCPSVRKLRRLVPGLE
                     RLGFGPGYHRSAIDRYLAATRPADVIRRERTETP"
     gene            14265..15470
                     /locus_tag="IO28_RS0104780"
     CDS             14265..15470
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     CaiA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 162.1; E-value:
                     3.5e-49)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346914.1"
                     /locus_tag="IO28_RS0104780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_031147003.1"
                     /sec_met_domain="CaiA (E-value: 8.8e-167, bitscore: 546.2,
                     seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.7e-12, bitscore:
                     39.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.7e-16, bitscore:
                     50.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.3e-12, bitscore:
                     38.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGDLTEPRTPEGHALLEVLDRHLPDLAAGAAEHDRNAAFPLDA
                     VRRMGADGVLGATVPREFGGLGVTSVHDVCLAVKRIAEADAAVALSLHMQFSRGITMSY
                     EREHAAGTGRALAERLLRLMGTERALISGALKDAGVTTELVPADDGGWRLTGRKILVSM
                     APFATHLVVAAQTRPASGPARIASAFLPADTPGLKAPDTWDGMGMRASASTEVVFEDCP
                     VPAADVFLRGPVGVRNDAAMAGQTVSSIGLLGVYAGIAQAARDFAVAGIARRGGQPAAA
                     VRTLVAELDVKLYTLRTALAAALTNADHHAHRTTVDPDERGRLMMAPFQYAKLVVNRTA
                     ADIVEDSMTLMGGASFTTSHPLSRHYRDVRAGWFMQPFTYADAVDHLSAHALGTDLEGS
                     TS"
     gene            15467..16573
                     /locus_tag="IO28_RS0104785"
     CDS             15467..16573
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 270.9; E-value:
                     2.6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487473.1"
                     /locus_tag="IO28_RS0104785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase"
                     /protein_id="WP_245240010.1"
                     /transl_table=11
                     /translation="MSGTRNGTGGGADREQRPADDGPVEERPVDALVRMSNLVTPMALR
                     VAATLRLVDHLRRGVTSPEALARATGADADALSRLMRHLAAAGVLEETAPGRYAPTRLG
                     DLLAEDDPSRQRSWLDLDQAVGRADLTFLDLREAVRTGRPQYEDRYGKPFWTDLSEDAE
                     LGASFDTLMTTREDAAFAAPVCAYDWSRARHVLDVGGAPGGLLSAIVRAAPGARGTLLD
                     LPGAAQRTRERIAAAGLDDRIDVVAGDFFDELPVSADAVVLSFVLLNWSDADALRILAR
                     CRDALRPGGRIVLLERAEAPSGGTRTSDLYFSVLDMRMLVFLGGRVRTDREWAALADAA
                     GLRIVSRSGPLVSPSVPLDSCLWELAPH"
     gene            16644..17537
                     /locus_tag="IO28_RS0104790"
     CDS             16644..17537
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 116.2;
                     E-value: 3.7e-35)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346912.1"
                     /locus_tag="IO28_RS0104790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_031147007.1"
                     /sec_met_domain="PF00561 (E-value: 1.7e-21, bitscore: 68.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-14, bitscore:
                     46.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAERIVTSKDVQLWSEDFGDPADPTVLLVTGGNLTAMSWPTEFVE
                     RLVADGLHVIRYDHWGVGRSTGWDPAERPYSYLRLAADAVAVLDGWDVERAHFVGMSMG
                     TVLCQLVALDHPGRMLSMSMMLGGALDVDFPGNIRRAFAGEPSADGLPLPQERFLEALA
                     VMNEEVDGPEAELERRVRRWKLFSGDETAFDEADFRRWEQQAIDHSGALTEPQVHYAVQ
                     PPPRERAPELRDVRVPTLVIQAMQDPIAPPPHGRHLAGLIPGAELVEIEGMGHALPRSV
                     HPPLAEAVLKHVRRVG"
     gene            complement(17551..18171)
                     /locus_tag="IO28_RS0104795"
     CDS             complement(17551..18171)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346911.1"
                     /locus_tag="IO28_RS0104795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DSBA oxidoreductase"
                     /protein_id="WP_031147009.1"
                     /transl_table=11
                     /translation="MTEQRTVDFWFDPVCPYTWITSRWLVEVTKVRPVTVHWRVMSLSV
                     LNEHRDDNPEGEWEDYMWAPVRVCAAVEERFGQQALGDLFTAMGNRFHLQGDWGNLAGA
                     LADAGLPEEIAEVAGSTEYDGAVRSSHAQAVALAGGDIGTPVVSVVRPGGERVGFFGPV
                     VSPAPTGETAGRLWDGLLLMAGVPGFYEVKRTRTEEPRFELAD"
     gene            complement(18199..18633)
                     /locus_tag="IO28_RS0104800"
     CDS             complement(18199..18633)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321817.1"
                     /locus_tag="IO28_RS0104800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ester cyclase"
                     /protein_id="WP_031147011.1"
                     /sec_met_domain="PF07366 (E-value: 7.1e-34, bitscore:
                     107.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRNIEAVRRMIAAYNTGRTDDVHEFIHPEYLNPATIEHGLGEGP
                     DAFAMAVAWVRKTFSEEAHLEEVRIEERGDWVRAYLVLYGRQVGPMVGIAPTGRRFSGE
                     QIHLLRVVDGRIRDHRDWPEYQSTYRQLGEPWPEPDGWRR"
     gene            18882..19232
                     /locus_tag="IO28_RS0104805"
     CDS             18882..19232
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346909.1"
                     /locus_tag="IO28_RS0104805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="WP_031147013.1"
                     /transl_table=11
                     /translation="MQPNDLDPSGSGVVTFINRFTVHASPEEFEKAFAETGRHLAGRDG
                     FLRYTLHRHAEDPTRWVNIAHWRDARAFRAAVGAPSFPQHVARLRELSTSEPGLYVPRQ
                     YVPAERAATEGL"
     gene            19232..20512
                     /locus_tag="IO28_RS0104810"
     CDS             19232..20512
                     /EC_number="2.3.1.-"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-400). E-value:
                     3.9e-51. Score: 166.1. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104810_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 484.1; E-value:
                     6.3e-147)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346908.1"
                     /locus_tag="IO28_RS0104810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_031147015.1"
                     /sec_met_domain="t2ks (E-value: 4.2e-241, bitscore: 791.5,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDASTGRRVVITGIGVVAPGAVGRKPFWDALTAGRTATRRITFFD
                     PGPYRSQIAAEVDFDPLGEGLTPQQVRRMDRAAQFAVVSAREGVADSGLDPAGLDPART
                     GVAIGSAVGCTMSLEDEYSVVSDGGRHWNVDASYAGRHLFDYFVPHSIAAEVARDVGAE
                     GPVSLISTGCTSGLDSVGHAVELIREGAVDVMVAGATDAPISPITVACFDAIKATTPRN
                     DEPGLASRPFDRTRNGFVLGEGAAVFVLEDAEHARRRGAYVYAEISGFASRSNAFHMTG
                     LRPDGREMAEAIRVAMLRAGVAPGDIDYVNAHGSGTLQNDRHETAAFKRALGEDAYRVP
                     VSGIKSMIGHSLGAIGSLEIAACALTIEHDTIPPTANLHEPDPECDLDYVPLTARRQPV
                     DTVLTVGSGFGGFQSAMVLRSPERAAS"
     aSDomain        19256..20431
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104810_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.90E-51"
                     /label="IO28_RS0104810_PKS_KS.1"
                     /locus_tag="IO28_RS0104810"
                     /protein_end="400"
                     /protein_start="8"
                     /score="166.1"
                     /tool="antismash"
                     /translation="VVITGIGVVAPGAVGRKPFWDALTAGRTATRRITFFDPGPYRSQI
                     AAEVDFDPLGEGLTPQQVRRMDRAAQFAVVSAREGVADSGLDPAGLDPARTGVAIGSAV
                     GCTMSLEDEYSVVSDGGRHWNVDASYAGRHLFDYFVPHSIAAEVARDVGAEGPVSLIST
                     GCTSGLDSVGHAVELIREGAVDVMVAGATDAPISPITVACFDAIKATTPRNDEPGLASR
                     PFDRTRNGFVLGEGAAVFVLEDAEHARRRGAYVYAEISGFASRSNAFHMTGLRPDGREM
                     AEAIRVAMLRAGVAPGDIDYVNAHGSGTLQNDRHETAAFKRALGEDAYRVPVSGIKSMI
                     GHSLGAIGSLEIAACALTIEHDTIPPTANLHEPDPECDLDYVPLTARRQPVD"
     gene            20509..21729
                     /locus_tag="IO28_RS0104815"
     CDS             20509..21729
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (47-370). E-value:
                     1.2e-29. Score: 95.3. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104815_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 638.6; E-value:
                     5.7e-194)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346907.1"
                     /locus_tag="IO28_RS0104815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketosynthase chain-length factor"
                     /protein_id="WP_031147017.1"
                     /sec_met_domain="t2clf (E-value: 1.6e-202, bitscore: 663.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTAVITGMGVIAPTGLGAESHWSRTLAGRAAIGRISHFDAERY
                     PSRLAGEIAGFDPREHGIPSRLLPQTDHMTRLSLVAAEWAIKDAGVDLAAMPEYGVGVV
                     TASSAGGFAFGHRELHNLWSKGPEHVSAYQSFAWFYAVNTGQISIRHGLRGPGGVVVTE
                     QAGGLDALAKARRQLRDGVPMVIAGGVDGSPSPWGWVAQLAGGRISTADDPERAYLPFD
                     QDAAGHVPGEGGALFVLETPESARARGVRSWYAEIAGQASTFDPAPGSGRPSTLRRAAE
                     LALDEAGLEPGDIDVVFADAAGVPDLDRAEAQAVRELFGPQGVPVTAPKTMTGRLGAGG
                     AALDLATAVLSIRDGVIPPTANVRRPVAEYGIDLVSAPRHVPVSAALVLARGHGGFNAA
                     AALTRQR"
     aSDomain        20650..21618
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104815_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-29"
                     /label="IO28_RS0104815_PKS_KS.1"
                     /locus_tag="IO28_RS0104815"
                     /protein_end="370"
                     /protein_start="47"
                     /score="95.3"
                     /tool="antismash"
                     /translation="RLAGEIAGFDPREHGIPSRLLPQTDHMTRLSLVAAEWAIKDAGVD
                     LAAMPEYGVGVVTASSAGGFAFGHRELHNLWSKGPEHVSAYQSFAWFYAVNTGQISIRH
                     GLRGPGGVVVTEQAGGLDALAKARRQLRDGVPMVIAGGVDGSPSPWGWVAQLAGGRIST
                     ADDPERAYLPFDQDAAGHVPGEGGALFVLETPESARARGVRSWYAEIAGQASTFDPAPG
                     SGRPSTLRRAAELALDEAGLEPGDIDVVFADAAGVPDLDRAEAQAVRELFGPQGVPVTA
                     PKTMTGRLGAGGAALDLATAVLSIRDGVIPPTANVRRPVAEY"
     CDS_motif       20827..20853
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IO28_RS0104815_0001"
                     /evalue="8.60E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="IO28_RS0104815"
                     /protein_end="115"
                     /protein_start="106"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="SSAGGFAFG"
     CDS_motif       21169..21207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IO28_RS0104815_0002"
                     /evalue="1.00E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="IO28_RS0104815"
                     /protein_end="233"
                     /protein_start="220"
                     /score="9.3"
                     /tool="antismash"
                     /translation="FDQDAAGHVPGEG"
     gene            21738..22523
                     /locus_tag="IO28_RS0104820"
     CDS             21738..22523
                     /NRPS_PKS="Domain: PKS_KR (9-118). E-value: 5.3e-12. Score:
                     37.8. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104820_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     257.8; E-value: 1.6e-78)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891732.1"
                     /locus_tag="IO28_RS0104820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_031147019.1"
                     /sec_met_domain="adh_short (E-value: 2.2e-37, bitscore:
                     120.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAQDDRHALVTGATSGIGLAITTLLCELGQRVFICARDEENVAL
                     TVERLREKGYEVAGLACDVRSTEQVGALVRAAVDRYGPVDVLVNNAGRSGGGPTAQITD
                     ELWLDVIDTNLNSVLRMTREALTTGGMLERGTGRVINIASTGGKQGVVLGAPYSASKHG
                     VVGFTKALGLELAPTGITVNAVCPGYVETPMAQRVRQGYAAVWDTTEEAVLERFEAKIP
                     LGRYTTPEEVAGLVGYLVTDRAAPVTAQAINVCGGLGNY"
     CDS_motif       21765..21833
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IO28_RS0104820_0001"
                     /evalue="2.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="IO28_RS0104820"
                     /protein_end="32"
                     /protein_start="9"
                     /score="14.0"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAITTLLCELGQR"
     aSDomain        21765..22091
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104820_PKS_KR.1"
                     /evalue="5.30E-12"
                     /label="IO28_RS0104820_PKS_KR.1"
                     /locus_tag="IO28_RS0104820"
                     /protein_end="118"
                     /protein_start="9"
                     /score="37.8"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAITTLLCELGQRVFICARDEENVALTVERLREKG
                     YEVAGLACDVRSTEQVGALVRAAVDRYGPVDVLVNNAGRSGGGPTAQITDELWLDVIDT
                     NLNSV"
     gene            22554..23507
                     /locus_tag="IO28_RS0104825"
     CDS             22554..23507
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-147). E-value: 4e-16.
                     Score: 51.5. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104825_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (160-295). E-value:
                     5.1e-09. Score: 28.5. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104825_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 430.5; E-value:
                     6e-131)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346905.1"
                     /locus_tag="IO28_RS0104825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatase/cyclase"
                     /protein_id="WP_031147021.1"
                     /transl_table=11
                     /translation="MTNNHRAEHRITVQAPARTVYGLIADVESWPRVFPPTVHVDVLDR
                     TAGEERIRLWATANDAVKTWTSRRVLDPGGLRVGFRQEVSQPPVAAMGGEWTVEPLSDT
                     VSLVRLTHDFRAVDDDPEGVEWITRAIDRNSDAELDALRRAAEQASGTGADDLSLEFDD
                     VVEVAGDPADVYDFLYDARRWQERLPHVNRVELEESTPNLQLLEMDTLTPNGAVHTTKS
                     VRVCFPSAAIVYKQLRTPALMTVHNGLWRIAKSTSGCTVTSTHTVVLSRDAVVPVLGEG
                     ATVGDARTFVRDALGRNSTATMLLAKEHAERAARER"
     aSDomain        22566..22994
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104825_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.00E-16"
                     /label="IO28_RS0104825_Polyketide_cyc2.1"
                     /locus_tag="IO28_RS0104825"
                     /protein_end="147"
                     /protein_start="4"
                     /score="51.5"
                     /tool="antismash"
                     /translation="HRAEHRITVQAPARTVYGLIADVESWPRVFPPTVHVDVLDRTAGE
                     ERIRLWATANDAVKTWTSRRVLDPGGLRVGFRQEVSQPPVAAMGGEWTVEPLSDTVSLV
                     RLTHDFRAVDDDPEGVEWITRAIDRNSDAELDALRRAAE"
     aSModule        22566..23438
                     /domains="nrpspksdomains_IO28_RS0104825_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_IO28_RS0104825_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="IO28_RS0104825"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        23034..23438
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104825_Polyketide_cyc2.2
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.10E-09"
                     /label="IO28_RS0104825_Polyketide_cyc2.2"
                     /locus_tag="IO28_RS0104825"
                     /protein_end="295"
                     /protein_start="160"
                     /score="28.5"
                     /tool="antismash"
                     /translation="FDDVVEVAGDPADVYDFLYDARRWQERLPHVNRVELEESTPNLQL
                     LEMDTLTPNGAVHTTKSVRVCFPSAAIVYKQLRTPALMTVHNGLWRIAKSTSGCTVTST
                     HTVVLSRDAVVPVLGEGATVGDARTFVRDAL"
     gene            23507..24823
                     /locus_tag="IO28_RS0104830"
     CDS             23507..24823
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 401.2;
                     E-value: 9.5e-122)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487499.1"
                     /locus_tag="IO28_RS0104830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="activator-dependent family glycosyltransferase"
                     /protein_id="WP_031147023.1"
                     /sec_met_domain="MGT (E-value: 9.3e-145, bitscore: 474.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFTTFGARNHVHAQVALAWALRAAGHEVCVASHPDLAEVIAR
                     TGLTAVPVGRELGEERLMEELREREDASRETYDEDAPDAQLLLAMDELRPEKLTYDHMH
                     GVFTAMTSAVFQNYSSAEMIDDLVGFARGWHPDLVIWDPLTFAGAVAARVTGAAHARLM
                     FGLDLVGRMRESYLAQVRRRPAALREDPLREWLGTVMERYGGEFTEDLVTGQWTVDPVP
                     TSLRLPADLPYVPVRCVAYNGRGSVPDWLREAPRRPRVCLTLGVSHREVMGGDQASVGE
                     LIEAVAGLDVEVVATLDARQLREVGSLPPNVRAVDFVPMDVLLPTCSALVSHGGSGTVH
                     AAFLYGVPQILVPGTMWDNAIRADLVQRSGAGLRLDAQTLTAAALRDALTRVLTEPSFT
                     AGAERLRRETLATPSPRDVVPLLESLTAEHRDDLVRNHV"
     gene            24816..25607
                     /locus_tag="IO28_RS0104835"
     CDS             24816..25607
                     /EC_number="1.-.-.-"
                     /NRPS_PKS="Domain: PKS_KR (18-177). E-value: 6.6e-10.
                     Score: 31.0. Matches aSDomain:
                     nrpspksdomains_IO28_RS0104835_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     207.8; E-value: 3e-63)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990784.1"
                     /locus_tag="IO28_RS0104835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_051892705.1"
                     /transl_table=11
                     /translation="MSDAAPLPPVTAPPPAPRSVVVTGGGSGIGRAIAHAFADEGAAVL
                     VVGRTAADLAGTAKGYDTIRTLAVDLTGADAPREVVETAVRELGGIDVLVNNAAALGHR
                     ALADVDPEQVAAQLGTNLAVPVLLTRAALDALAADGGGTVVNIGSSGARGSRAWPGNSV
                     YGAAKAALDFLTRSWAVELAPRGIRAVGVAPGLVDSGFAERAGMSPEQYDGMLHHVGAL
                     TPQGRVGTPQEIAWWVTHLTRPEASHLTGAVLPVDGGLSLT"
     CDS_motif       24870..24956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IO28_RS0104835_0001"
                     /evalue="5.30E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="IO28_RS0104835"
                     /protein_end="47"
                     /protein_start="18"
                     /score="22.3"
                     /tool="antismash"
                     /translation="SVVVTGGGSGIGRAIAHAFADEGAAVLVV"
     aSDomain        24870..25346
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IO28_RS0104835_PKS_KR.1"
                     /evalue="6.60E-10"
                     /label="IO28_RS0104835_PKS_KR.1"
                     /locus_tag="IO28_RS0104835"
                     /protein_end="177"
                     /protein_start="18"
                     /score="31.0"
                     /tool="antismash"
                     /translation="SVVVTGGGSGIGRAIAHAFADEGAAVLVVGRTAADLAGTAKGYDT
                     IRTLAVDLTGADAPREVVETAVRELGGIDVLVNNAAALGHRALADVDPEQVAAQLGTNL
                     AVPVLLTRAALDALAADGGGTVVNIGSSGARGSRAWPGNSVYGAAKAALDFLTRS"
     gene            25672..26958
                     /locus_tag="IO28_RS0104840"
     CDS             25672..26958
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 243.7; E-value: 5.4e-74)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04515.1"
                     /locus_tag="IO28_RS0104840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="P450-derived glycosyltransferase activator"
                     /protein_id="WP_031147027.1"
                     /sec_met_domain="p450 (E-value: 3.2e-13, bitscore: 40.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTMNESELGRVLLTHRGVQWIIGTKDDPYALLVRAAGDDPHRLG
                     ELIRERGPLYRSSAEAWVTAHHEVAAAALADPRLSVRHPDADAPAAQDGGEQREPMPWE
                     VPALREILPFGGAFLTAGRADCERVGELLEPLLGAKALERRRPVAEQALRRALAEAGSG
                     FDLRTEVADPFAAGIVRELLGVPEEDHDRFAALCRGAAGLLDATVCSPHLRTARELIAS
                     VEGMRSLLAGVIAQRREKPGDDLVSALLAATHEDEVRSVCTLLALVGTELSATLFCDAV
                     AELLDHPAQWRALCEDPGLAPAVVEETLRHAPPVRLVPLYALEDLELAGTPVPAGGQVV
                     VAVEAAGRDSAVHPEPAAFDPARERAAEPLAFAEGLPTSLPAPTARFLAEAGLRALAAE
                     VPGLRPVGPVLRRLRSGVTGAVIEMPVAR"
     gene            27160..28044
                     /locus_tag="IO28_RS0104845"
     CDS             27160..28044
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.9; E-value:
                     8.9e-54)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346901.1"
                     /locus_tag="IO28_RS0104845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_245240025.1"
                     /transl_table=11
                     /translation="MRYGSKDVLNGVDFSVRRGEVLALLGPNGAGKTTTIEIMEGFRTR
                     SAGEVSVLGVDPAKGDEEWRARLGVVLQSWRDHGKWKVRELLAQLGDFYRPYSTPERPR
                     PRDVDELISMVSLEEQADQKIGSLSGGQRRRLDVAIGIVGRPEVLFLDEPTVGFDPKAR
                     RDFHDVVHRLSDLEDTTILLTTHDLDEAEKLSDRILILAGGQIVADGSADQLARQTSGK
                     AEVRWSLSGEQFVHATPDASTFVHELFKQHGDRVRDLEVRRASLEDTYMTMVRQHEAGR
                     SEEAIAAFREAGR"
     gene            28041..28895
                     /locus_tag="IO28_RS0104850"
     CDS             28041..28895
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 61.8; E-value: 9.9e-19)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346900.1"
                     /locus_tag="IO28_RS0104850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_030957368.1"
                     /transl_table=11
                     /translation="MNPTLYAVRLGLRRGWTEFRQSVTSPGDIIYYLFLGGVFLGVLFF
                     MRNSTVEGTDLSLATLTMPSMIGGLLAFQALGGAAFALAAEREDGTLLRARTVPQGLVG
                     YIAGRVLGIALSTLLTLVIILVPSVFLFDDLMTGDLAKWLNLVWVLALGLLATLPIGLI
                     IGAMVKNPRGANTWGIFPTMGLMAISGIFYPITSLAGWLQGIAQLFPVYWVGLGTRAAL
                     LPDAAVAVELGDSWRRPMTAVVLLAWAVVALVIAPRVLGRTVRGETGSKVEARQQEALK
                     RVG"
     gene            29065..29289
                     /locus_tag="IO28_RS40515"
     CDS             29065..29289
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890117.1"
                     /locus_tag="IO28_RS40515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_037631637.1"
                     /transl_table=11
                     /translation="MHNRIAVLRVERAITRRQLADALGVHYQTVGYLERGEYSPSLHLA
                     LRIAEYFEVPVEVIFSTTPFPRIGSTPPA"
     gene            complement(29354..30640)
                     /locus_tag="IO28_RS0104860"
     CDS             complement(29354..30640)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 396.5;
                     E-value: 2.6e-120)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891742.1"
                     /locus_tag="IO28_RS0104860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="activator-dependent family glycosyltransferase"
                     /protein_id="WP_031147034.1"
                     /sec_met_domain="MGT (E-value: 1.1e-143, bitscore: 470.5,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFTPFPASTHVHTQVPLAWAMRAAGHEVRVATRPDVVEDINN
                     AGLTAVAVGGVLDVAATMNPEYTDEPDEIRDEAWLDVLDISETRPEKLTLPYVHGVLTA
                     WTSFVYQNTLPDDTTGELIDFARSWRPDLVVWDTMYYPGALAARISGAAHARLMFGLDL
                     VGLMRQHYLRGLAGLPPALREDPLEEWMDRILRRYGREFTEDLVVGQWTIDPVPPSLRL
                     PVDLPSVPVRYVPYNGEAQVPDWLREPPPRRPRVCLTLGRSFREVVGADRTSVGDLLEA
                     VADLDVDVVATFTADQLDPGRRVPDNVRVVDFAPLDALLPTSAAIVHHGGSGTLQTALA
                     HGVPQVIVPAKMWCNVPKAHRVRDAGAGLCIDPEALTPQGLRAALVRVLQEPSFRAGAD
                     RLRREVLATPSPADVVPVLERLTAEHRSR"
     gene            30808..32415
                     /locus_tag="IO28_RS0104865"
     CDS             30808..32415
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 367.9; E-value:
                     1.6e-111)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346897.1"
                     /locus_tag="IO28_RS0104865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_031147036.1"
                     /transl_table=11
                     /translation="MATADKEVDVLVVGAGLGGLSTTMFLARLGVPVLMAEKHPTTSIH
                     PRAIGQNPRTMELLRLGGIAEQVQDATDHRGAKGHFTTRVAETVRGEVLGTFEEGFDNL
                     VATTAPCSPMAWALAWQDQLEPLMLDRARRDGAQIRFAAALVSYEQDADGVSALLRDRE
                     SGAETTVRARYLVAADGDRSPIREGLGIARRGHGSLSHVVGMIFEADLSGVLTSDASGL
                     YYLRNPAFSGIFIGSDRPERHTFLVEYDPERGESAEDFTPDRCLELIRTGLDAPDLEPK
                     VLDVQRWEMAARIAERWRAGRVFLVGDSAKVVPPTGGLGGNTAIGDGYDLAWKLSAVLT
                     GQAGPGLLDSYEPERGLVARLVMDESMALYASRLAPHLQDRMAEPVGYAEVILGFRYRS
                     DAVLIDDDDPARVESPARPTGRPGFRMPHVWVLRAGERISTVDLFGSGWLLMTGADGAG
                     WTGWARSASRELGVPVEVHGPATGLEDPDGELAERFGIGTGGASLVRPDGIVAWRTATR
                     PDDPAAALRDALTRVLSR"
     gene            32464..33258
                     /locus_tag="IO28_RS0104870"
     CDS             32464..33258
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346896.1"
                     /locus_tag="IO28_RS0104870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_031147038.1"
                     /sec_met_domain="PhyH (E-value: 1.9e-38, bitscore: 124.2,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARSAPVTADVLTDEARRHYQENGFVRIPEVLTPSEVERFRAAS
                     EEVVAQHGPEIWGAGEDEVQVHFVAQAWLKHEALRDLALHPAITGMAKRLAGGPLRLYS
                     TDILLKSGRETLNTLPTLVHDDETGLPLHGIDRTLTAWVALVDVPAESGCLSYVPGSHL
                     RDAAHRQVHMTSFAEYRPIADIWPDYDWQPRITVPLKAGDVAFHHCRTVHMAGANLTDN
                     PRMGHGIVYMDDGSTYWPGTEDAHISHMAPGDPLDNEKFPLI"
     gene            33283..34446
                     /locus_tag="IO28_RS0104875"
     CDS             33283..34446
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 110.8; E-value: 1.2e-33)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04515.1"
                     /locus_tag="IO28_RS0104875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="P450-derived glycosyltransferase activator"
                     /protein_id="WP_051892707.1"
                     /sec_met_domain="p450 (E-value: 5.3e-13, bitscore: 39.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHGTWNRTDIGELGRRLQRAHGEVWLHQVKGDPYADLLRGHAEDP
                     RPGQERIRALGPLWRSTTGAWVTADHRLAGELLGAGWPHRPLADDEAHVPVDDAGLGGD
                     AAHYERLHGYARDAVPPAAVQAVSERVVGALAADFDLVTDLAEAVPTNLLAATLGPAGA
                     DRRELARACTAAGVVLDGLLCPQRLDVTRRAVAAVGRLRELLADPAADPEAGPGAGPHE
                     AAVLLATAGVRTAASLIAGSVLAVADHPEEWSRVAEDPGHAALVVAEVLRHDPPVRIHP
                     AVALADVEFAGQHVRAGERVVVLVAAANRDPEVFDDPDRFVTGRPVEALVPALHHRVTL
                     PFARAQAEAVLRALVAARPRPRRSAGHLRSRRSPVTGHLLGCPLTTG"
     gene            34474..35757
                     /locus_tag="IO28_RS0104880"
     CDS             34474..35757
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     oligosaccharide: MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 324.7;
                     E-value: 1.7e-98)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346894.1"
                     /locus_tag="IO28_RS0104880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="activator-dependent family glycosyltransferase"
                     /protein_id="WP_031147042.1"
                     /sec_met_domain="MGT (E-value: 3.2e-119, bitscore: 390.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFTSIEGNHFQQMVPLAWALRTAGHEVRAACNESLVDTVTQT
                     GLTAVPIQSPTLWEQLDGFQKEAISLFNEIGTSKQDPSKATWEDHLSYENMVVPALYQP
                     LNNDAQIDQLVAAARSWQPDLVVWESFSIAGAVVAVATGAAHARLVSGPELALQMVTRG
                     HFVRHRDRQPEPLREDPTAEWLDWTLERLGSDRRFDETMLTGQWVVDTRPASLRQQLDL
                     PTVPMRYVPYNGRCVVPGWLNEPVERRRVCITLGTSITSEESERFRLGETLAALFRSLA
                     GLDVEIIAALDPAQRGALPDLPDNIRTTDFVPLNELAPSCSVIVHHAGYQTKATADLHG
                     VPQVVIVGYEWVSEDMGEEYEKSGTTLAVSARDLTAEVLREKILRLLDEPSYTERAGAL
                     RDEIRAMPTPNEVVPVLEEMTREHRRRG"
     gene            35835..36644
                     /locus_tag="IO28_RS0104885"
     CDS             35835..36644
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346893.1"
                     /locus_tag="IO28_RS0104885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FkbM family methyltransferase"
                     /protein_id="WP_031147044.1"
                     /transl_table=11
                     /translation="MPNPWDLPDELPTDLPVSRCELPDGRVLSAVQEAEAHTLWEEISS
                     AAPYRKAAEGLRPGEAVIDVGAHIGLASLLFGGLAPESRVLAFEPAPKAYTCLEDNLAR
                     LLPGATAFRQALGAASGTSELTYRPYVASASTLYDDAEDDARNLEAHLDNIGADERTRE
                     VVRRTFNVSQRVTVEVTTLASVMAEHDVDRVGLLKIDVERGELDVLDGIDPACWPRIRR
                     VLLEVHDIDGRLGRVVSRLSGLGFHATVSQWGVYVGGSVHLVLAERD"
     gene            36666..37910
                     /locus_tag="IO28_RS0104890"
     CDS             36666..37910
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016150.2"
                     /locus_tag="IO28_RS0104890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_051892708.1"
                     /transl_table=11
                     /translation="MSDGAPRPSGSGATADRALAPDLARGLMLLIVALVHAHMFVSGSA
                     AVIRGYPPVAGSPADAATAGVLTVLADSRSFPMFALLFGYGTGRILARERERGRDGPGA
                     RAVLRRRARLLLLFGAVHALLLFAGDVLGAYGLLALVAVGLTGARDRILFTVAGAGVAV
                     GTVLYASMLAAGVSGDPDDTAAAMFLAADPVSDAAYRIGTWVVTTPLFAVMSLGPFLIG
                     AHAARQRVLEEPGRHRVLLRRVAVTGTALSVAGGLPLALVTSGVWTTAPSDVAWGLSAL
                     HVLTGYAGGCGLAAAVALLALRLEGRRSRAVTAVAACGRRSMSAYVWQSVVWLVLFAPY
                     TFGLGDRVGVLGSALVALGAWGAGVLLADLLRRRGRRGPAEALLARVTRRAPPAAAAAP
                     EREDAVREVNGPPSP"
     gene            complement(37888..38748)
                     /locus_tag="IO28_RS0104895"
     CDS             complement(37888..38748)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 116.3; E-value:
                     2.6e-35)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346891.1"
                     /locus_tag="IO28_RS0104895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_031147048.1"
                     /sec_met_domain="PCMT (E-value: 5.5e-12, bitscore: 37.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTTYKAHVTAAFDRAAGSYDRMGVTFFTPMGRRLVERAAPQPG
                     QRVLDVGCGRGACLFHAAALVGDQGRVLGIDIAPAMIEEARKEAADLGIANVELRVMDG
                     EFPDLPARSFDVVTGSYSLIFFPEARAALPRYAELLADGGRIAFTSPVFDDDAFPFLPP
                     VFTELIPRSLLENLPPQWRPEELQKRFNSWLAQEADLRRALESAGFHEVEITDEPVDLV
                     APSGEAWVAWSHTQGMRLLWEHLPDDDRERLRVRLTGALDEMRHDGGPLSIETPVRYVT
                     ATVAR"
     gene            39043..39651
                     /locus_tag="IO28_RS0104900"
     CDS             39043..39651
                     /EC_number="5.1.3.13"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947374.1"
                     /locus_tag="IO28_RS0104900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="WP_158714712.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 2e-60, bitscore:
                     194.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRKLSVEGAIEFTPRVFDDERGIFLSPYQESAFSDATGGHTLF
                     RVAQTNHSRSRKGVVRGLHYTLTPPGCAKYVYCARGKTLDIAVDVRVGSPTFGKWDAVL
                     LDTEVFRSVYFPVGVAHGFVALEDDTVVSYLLSGEYVPEHELALSILDPDLALPIPGDI
                     EPVLSERDLAAPTLEKAASDGLLPDYAECLAIDRALRPA"
     gene            complement(39736..41208)
                     /locus_tag="IO28_RS0104905"
     CDS             complement(39736..41208)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346889.1"
                     /locus_tag="IO28_RS0104905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NDP-hexose 2,3-dehydratase family protein"
                     /protein_id="WP_209441455.1"
                     /transl_table=11
                     /translation="MNRIALPHPSPTALRTLQDRLARSALAEESRVRQPAPFVTWFADA
                     RERSGLRVDRVDLDGLENWERDPRTGALRHSSGGFFAIDGLDVRFPSGPVPHWQQPIIH
                     QPEVGVLGLLAKEFDGVLHFLMQAKVEPGNRNHLQLSPTVQATRSNYLRLHKGRAVPYL
                     GYFQERTRHRVVADVLQSEQGAWFYRKRNRNIVIEVTEDIAVEEDFRWMTLGEIHRLLA
                     VEDIVNMDTRTTLSCLPLAGGGLDVLLDTGDGFRDALARSCAGEPGGVHDVDELQSWIT
                     EHRAQNDLTTRSVPLVELRDWHSSPERVSHTSGRFFSVIGVNVSAGTREVRGWSQPMLE
                     PHGTGVIAVLVKQIDGVLHILLRASVEPGYVDGVELSPTVQFTPESVPPGAALPRFVDD
                     VLSAPPERTRFACLLSEEGGRFHHALNRYLVVEAEGDAESMEDRDFRWVTLDQLSTLLR
                     HSHYLNVQARTLVACLHSLLAPRRPGGEALGL"
     gene            41972..43900
                     /locus_tag="IO28_RS0104910"
     CDS             41972..43900
                     /codon_start=1
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     556.4; E-value: 2.2e-168)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.2"
                     /locus_tag="IO28_RS0104910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_266496847.1"
                     /transl_table=11
                     /translation="MLGPLEILDGPCNVVPTAPKPRQVIALLLMRRNTLVQTSELIDEL
                     WESDPPASAMTTLQTYIYKLRKILTARNSEEILFTRPGGYTLAIPDRSVDLHRFETEAG
                     EGKSLLKNGDAAGAAEALRRSLALWRGSALVDVVPGGLLSSYVTRLEEFRERTLDLRIE
                     ADLQLGRHQELISELKSLVLSRPLHENVHASLMIALHRSGRRHEALEVYQVLRRSMIDN
                     LGLEPGKELRALHQALLSEATGGVLYERHQQPVLVEPDRGPVGHPEPEEPPVAAAPRPA
                     AAPGVPAPAQLPPDIADFTGRESIVDQAPALLAGVGERDRPPTAPAVAVISGMPGVGKS
                     ALAVHMSHTVRPFFEGGQLYADLRGSTGRGTDPTEVLHGFLRALGVAESEIPADLEERS
                     KLFRSTTVGRRLLILLDDVSSLADVRSLLPGDPECSVVITSRRRLHGLGGAWNVNLDAM
                     DTAEGRELLARIIGSARVRRERNAANQLMETVGGHPLAVRCIGGRLSGSPGLTLSGLAT
                     QLNCSEKLLDELRLGELDVRSRYDFSYEGLGRVEQSVFRLLSILPPRRFTADSVVELLG
                     SDSRSVEHLLQRFVDSHLINIVRWEDGGAHYEFPELTRVYARERLLDTLSGDGPEHEGI
                     WPDRRRC"
ORIGIN
        1 tcagccgccg acgatcctgg cgaccttgcg gacgtcctcg accagcctgg cctgcaggag
       61 cgactccgct tcgccgaccg gtccgtcccc gccggccagg acggcggccg tgaacgcggc
      121 cagcgcgttg cgcacctggt cgtccgcggg catcgccagc tcggtcagcc ggtcctgctg
      181 ctggagccgg accacgggct tgagcacctc cggcggggtg tacgcccgct ccaccgagat
      241 ccgtcccgcg ccgccccaca gcgcgtagcg cgaccggtag gagtggcgga agccgaactc
      301 cagctgcgcc gcgacgccgt cgggggcgca cagcagcgcc gtgcccgcca cgtccacgcc
      361 ggtcgcgtcg tccacccgca gggtggccgc cagcacctcc ggctcaccgg acaggtacat
      421 ctgcgccgtg cgcagcggat agacgccgac gtccagcagc gcgccgccgc cgagcgaggg
      481 ggcgtaccgg aaccccgtgg ggtccagcgg cggtacgccg aaggaaccgg agagcacctc
      541 cagcccgccg atggcgcccg actctacgag cgagcggacc ccggcgtgct gggagtggtg
      601 caggaacatg aagttctcgg cgaggatccg gcggtgccgc cgagccagct ccatcagctc
      661 ggcggcctcc gcgtgggtcg tgcacagcgg cttctcgcac agcacgtgct tgccggcgag
      721 caacgcctcg gccacctgct cgaagtggag cgcgggcggg agcgggacgt acaccgcgtc
      781 gatgtcgtcc cgctccagca gcgtccggta gcccttgacc ccggcgcacc cgaaccgggc
      841 cgccgcccgc tgcgccttcg cggcgtcccg gctggccacc gcgacgagct cggccgactc
      901 ggccgccgcg atggccggca gcatccggcg cagcgcgatg tccgcgcagc cgagcacacc
      961 catgcggacc cggcggccgc cgtccccgtc ccgcccggtg gggacagggc tcacagcgag
     1021 gccagtacgt cgtggagcgc gccgatcacc ttgtcctgca ccgccgggtc cagcgagggg
     1081 tacatgggca gcgagaagat ctcctcggcc gccgactcgg tgacgggcag ggaccccttg
     1141 gcgtatccga ggtgggcgaa gcccgtcatg gtgtggaccg gccacgggta gctgatgttc
     1201 agctggatgt cgtaggcctt cagcgcctcg atgatcgcgt cgcgccgcgg atggcggacc
     1261 acgtagacgt agtggacgtg gtcgttgccc ggcgccgtcg acggcaggac cagaccggtg
     1321 ccggcgaggc cctcggcgta ccggcgggcc accgcgcgcc ggccctcgac gtaggcgtcg
     1381 agccggcgca gcttgcggcg caggatctcc gcgtgcagct cgtccaggcg gctgttgtgc
     1441 ccaggggtct ggacgacgta gtaccgctcc tccatgccgt agtaccgcag ccgccgcagc
     1501 gcggcgtcca cggccgggtc cgaggtgatg acggcgccgc cgtcgccgta ggccccgagc
     1561 accttggtgg gatagaagga gaacccggcc gcggcccccc aggtgccggc gaggcgtccg
     1621 ccccggcggg cgccgtgggc ctgcgcgcag tcctcgaaga ccaccaggcc gtgctcgtcc
     1681 gccacggcct gcagcgcggt catgtccacg cactggccgt acagatggac cggcagcaga
     1741 cacctggtgc gctcggtgac ggccgcggac acctgctcga cgtccatcag ataggtgtcg
     1801 gggtggacgt cgacgaagac gggcgtcgcc cccacggagt cgatggccac caccgtgggc
     1861 gcggcggtgt tcgagaccgt gatcacctcg tcgccggggc ccacgccgat cgcctggagg
     1921 cccagcttga tcgcgttggt gccgttgtcg acacccaccg cgtgcccgac cccgtggtag
     1981 gcggcgaact cctcctcgaa gccgcgcccg ctggcgccga gcacgagctg ccccgaccgc
     2041 agcacggtct cgacggcgtc gtggatgtcc tcccgctcgt tctcgtactc gcgcaggtag
     2101 tcccatacgt aagtggtcat ggctgagtca ctgtctccgc tcgtctccgg cacgtgcctg
     2161 gctggggtcc tactgccgta caccgacgaa cagaccgcgg ccggtcgggt cgccgggcag
     2221 gtactcgacg gtgcaccccg cgtcggcgaa cgccgcgagg tactcgtcct tggtgaagag
     2281 ggtgaggacg tcgacctcgg tgaactcccg gatgccggag ctgtcgccga ccaggaaccg
     2341 cacctccatc cgggtcgcgc ggccctggag ggtcgagtgc gagatccgcg ccaccgtgcg
     2401 gccgttctcc cggccgaggt cgcccgcgac gtagccctcg acatggttct cagggaacca
     2461 ccacggctcg atgacgagca ccccgccggg gcgtacgtgc cgggccatcg accgcaccgc
     2521 gtcacgcatg tcggcgacgg tgccgaggta gccgatggcg cagaacatgc acacgaccgc
     2581 gtcgaaggtg cggccgaggc cgaaggcgcg catgtcgccg gggtggaccg tcaccgccgg
     2641 cagccgccgg tgggccagct cccgcatcgg ggcggcgatc tccagaccct cggtgtgctt
     2701 gaacagcgtt ccgaaggtct ccagatgggc tcccgtcccg caggccacgt cgagcaggga
     2761 gtccgcctcc gggcaccgcg cccgtacgag gtccgtgacg tgggccgcct cggccggcca
     2821 gtccttgccc cggctgcggt agaagatctc gtagacctcc gccagctcct gtccgtacat
     2881 ctctctccag tcggtgtcgg gtcggggtcg gtgccgggct cactcgtcga ccatggcgac
     2941 cgccctggtc cagccggcgc ccgcgcccgc gatcttcacg gggaagcaga cgacggtgaa
     3001 cccgtacggg gcgggcaggg cgtcgaggtt cgccagacgc tcgatctggc agtactcccg
     3061 gtcgcggccg gcgaagtggg ccggccacag caccgaacgg tcaccggtgc gccgatagcg
     3121 ctcgatgatg tcggtgaagg gggcgtccag gctgaacgcg tccgtcccga tcacccgcac
     3181 ccccaggtcc agcagcaggt gcacggccgg cccgtccagc ccggcgaact cggtgaagta
     3241 ctccggggtg cccgcccgcg ccgaggcccc ggtgcgcagc aggacgatgt ccatcggcgc
     3301 cggggtgcgg ccgatccgct cgaactcctt ctccagccgc gcggccccga cgacaccggt
     3361 cgccgcgtcg gtgaggtcga gcacgatccc gggcctgcag aaccagtcca gcggcatccg
     3421 gtcgatgtgc cggggcactc cgtcgccgta cccggccctg gagccgtagt gcgacggcgc
     3481 gtcgacgtgc gtgccggtgt gcgaggtcag ggtgatccgg tcgagcgaga ggaactcccc
     3541 gtcgggcagt tcctccgggg agaactccag cccgaagtgc gtacgcatct ccgcgctcat
     3601 gtgctccgca ccctgacggg gcgtcaacac ctcgtgcacc accggatccg gctcgtacgc
     3661 cgtggcgtcc accgccgacg acaggtcgat caaccgcaca cggacctcct acgcaccgaa
     3721 ccgctcgcac cgacgagcag atcgtgctcg gtgccgacgg agaagcgctc aagcctcact
     3781 cggctcccgc gcgtcacgtt cgagccgatg tcgaagggcg tcgtgaatcg ttcgcgggtg
     3841 cgcccgttcg ccccgaacgg gaccagcgtg aggaggacgc ggtggcaatg cggacgggaa
     3901 cctcgtcgtc gttcgattcc ctctatgccg aagtgcaaca gttctacgcc gatcacatgc
     3961 acctgctcga cgccggggac ggcgagggct gggcacggac cttcaccgag gacggatcgt
     4021 tcgcgccgcc ctcgctgccc gagcccgtcg tcggccgggc cgccctggcc gagggggtcg
     4081 acaaggccgc cgcggcgctg gccgaggccg gcgaggtgca ccggcacctg ctcggcatgg
     4141 tgtcggtccg gccgggcgag gacggctccc tgagcgtccg ttcgtacgcg cagatcatcg
     4201 ccacggcccg gggcggcagc ccccggctgc acctgatgtg cgtgtgcgac gacgtgctcg
     4261 tccgggtcga cggcgaactg aaggtgcgcg aacgccgcgt cacccgtgac gaccggcgcc
     4321 cgtgaccgcg gcgccgccgg gacccgccat gaccacggga aacatcgagg aagggaggac
     4381 gcggtggtga ccgcagaaga ggtcggcagg gcgaccgggc gccgtacggt cgccgtactg
     4441 ggcgcgaccg gcaccatcgg acggcaggtg gccgcggcgt tcacgcgcgc gggacacgag
     4501 gtgctcggcg tggcccggca ccccgcgccg cacaccgccc ggcatccctt cgtcccgctg
     4561 gacgtggcgg aggcggatcc ccgggacatc gccgacctac tcgccgaacg gaacgtggac
     4621 gtcgtcgtca acgccacggg cggatgggtg gtgaccgagg aggccatgca ccacgcccac
     4681 gtgcggctgg tggagcggat gctcgccggc gtcgcgaagc tgcccacccg cccccgcgtc
     4741 gtccacgtcg gcagcatcca cgagtacgga ttcgtgtccc cggaccccga cggcatcgac
     4801 gagtcggtgc cgccggagcc gaccaccccg tacgcccgga cgaaactggc cgggtcgcag
     4861 gccgtactgg aggcggcccg gaccggggac gtcgacgggg tcgtgctgcg cccggtcaac
     4921 gtgtgcggtc cgcacccgtc ggaggcgagc ttcctgggca ccgtgctgaa ccgactgcgc
     4981 gcactgacgc cgggggagcg gctggagctg gtcatcgcgg acgcggcacg cgactacgtc
     5041 gacgtgcgcg acgtcgcctc ggcggtcctg gtggccgcgg acgcggccgc ctccggcacc
     5101 gtgttcaaca tcggacgcgg tgaggcgccc accatgcgcg aactggtcac caccctggtc
     5161 gaggcggcgg gattcccgcc cggcacggtc aaggagaccg gcggggcggt ggagagcaag
     5221 ggcggcggct ggaccaaggc cgacatccgg cgcgcggaac gggtactggg ctggcgcccg
     5281 gccatcgggc tgcgcgcctc cctgcacgac atgtggaagg cggcgggctg agccccggcc
     5341 gccaccccgg gcgcccgtcg gcgggcgccc gattccccac gagcggagag aggtacgagt
     5401 gatgagtgaa ctgaccctgc cggtactggt cgagatcttc cgggagtgcg cgggcgaggc
     5461 ggacggcgcc gatctggacg gcgaggacgt cggtgacgtc gagctgaacg tcctcggcta
     5521 cgactcgctc gccctgctgg aggcgatcag ccaggtcgag cggaggtact ccatcggcat
     5581 gccggacgcg gagacccgca tcaagacgct gaaccagttc ctcgagcagg ccaacgaaca
     5641 actggtgcag cggtcctgaa ccccgccgcc ccgtccgccg gatcagccgg cggacgggac
     5701 gccgacgaag agcccgcggc cggcgggcgc gacggggacg tagtcgacgc ggaaaccggc
     5761 ggccccgaac gccgcctcgt accgctcccg tgagaacagg ccgatcaggt gcgtctcgtg
     5821 gaagtgccgg acgcccgacg ccccgtccgc gacgagatag tgcacgttca tccgggaagc
     5881 gtccccctcc cgtacggagt gggagacccg ggacacggtc cgccccccga cggtcgccgt
     5941 ggccccggcg acatggccgt gcaggtacgt ctcggggaac caccacgggt cgacggccag
     6001 caccccgtcg ggcgccaggt gccgcgcgaa ccggcgcagc gcgccgacca gcgcgtcctg
     6061 cgtcagcagg tagccgatcg agccgaacat gcacgtgatg acgtcatagg tgcggcccag
     6121 ttcgaagtcc cgcatgtcgc ccacgtgcac gggcacgtgc ggcagcgccg cctgcgcgaa
     6181 gcgggccatc ggctcggaca gctccagccc ggccacctcg tcgaacagct cgtcgaagcg
     6241 gcgcagatgg gccccggtgc cgcaggccac gtcgagcagg ctcgccgcgt ccggcttgtg
     6301 cgcccgcacc tgccgctcca cttcggccgc ctcctcgagg tagtccttgc cgcggctgcg
     6361 gtggatgagc tcgtagatct cggccagttc ggctccgtac acggcgacct cgttcgacgg
     6421 gcacccggcg gcgacagcgc gacgggtacg gcggaaggga caggggtccg gcgggaccga
     6481 tggtcgggcc ggccgctaga ggaacgccgg agaccggctg gacgcacggg cccccggggc
     6541 cgctcgcggg gccgggcccc gctgtcgagc agggttcgaa tcccccctgc cagggtcggg
     6601 gcaccacgga cccgcggcac aggttggagt ccccaccgtg agcacaggaa cgagcacaga
     6661 ccggaccgcc gacgcgcgcg ccggctcccc gtcggcagag gtcgccgagc tgctggacgt
     6721 actgcgcggc tacctggacc tggcacccca gctcagtctg ccgccccgcg cgttcacctc
     6781 gcccgagctc tacgagctcg aacgcacccg cgtcttcgga cgctcctggg tgctcgtcgc
     6841 gcaccgcgac gaactcgccg agccgaacag ctacgtctcg gtcgacatcg cgggcgagca
     6901 gatcctggtc acccgcgacg cggacggcgc gctccacggg atgtcaccga tctgccggca
     6961 ccggatgatg ccgctcgtcg aacccggcgc caccggacgg gccgactcct tcacctgtcc
     7021 gtaccacctg tggcggtacg ggctcgacgg ccgcctcatc ggcgccaccc acatgcggcg
     7081 gaacccggac ttcgacccga aggactgcag actccccgcc ttcgccgtcg aggagtggca
     7141 cggcttcgtg tacgtgaacc tcgacgcggc cgcggccccc ctcgcccccg aactgaagcg
     7201 gatctccggc gacctgacca actaccggct cgacgagatg gcgcagctcg gctcctggag
     7261 cgaggagtgg gcgtgcaact ggaaggtcgc cgtcgagaac gcccacgaga actaccacgt
     7321 catgggcttc cacccggaga ccctccagca gtcgacgccc ggcgggtccg acacggacgt
     7381 gcgggtcgac tccccgtggg cgctgcgcct gctcgtcccg ttcaccgagc cgcaggaggc
     7441 ctacgccctg ccgctgacgg acacggagaa ggcccacctg tacggcatct tcgtcttccc
     7501 cgcggcgagc ctggccgcgg cgggcgagat ggtcatctgg ctcagcctca tcccgcagac
     7561 gatcgaccgg acgctggtcc gcggcggcat cctcgtgccg cgcgccgcgc tggagggcgc
     7621 cgacctcgac gagatgcgcc ggcaggccga gacgtacgcg ggaatgatca acagcgagga
     7681 ccgcaacggc ctggaggccg tccagcgcgc ggtggggtcc cgcttcgccg cacgcggcca
     7741 cctgagcccc aaggaacccg gcgtcgtggc cttctaccag aacctggcac gggccctgct
     7801 gcgcgccgac gacgactggc cgggaggcct gtgagcccgc ccgccgggcc cgtccgcccg
     7861 cgcacgccgt gacgattcgc ccctttgccc atccgccact caaggaagag gacacccatc
     7921 gtgctcagtt gtcggatctg cggcggtcgg ctgcacgagt tcatcgactt cggacagcaa
     7981 ccgctctcca gcgggctcct cgagcccgaa tacctcggcg acgagttctt cttccggctg
     8041 gccgtcggcg tctgcggcga ctgcaccatg gtccagctca cggaggaggt gccgcgccac
     8101 ctgatgttca acagccacta cccgtacctg tcgtccggat cctccgtcat gcgcgggcac
     8161 ttcgaggaga ccgcccggca cttcctggcg accgaactca ccgggaagga cgccttcctc
     8221 gtcgaactgg gctgcaacga cggcgtcatg ctccgcgccc tggccgaggc cggggtccgc
     8281 cacctcggcg tcgaaccctc gcagagcgtg gccgacatcg cgcgccgcca gggcatccgc
     8341 gtcgccaccg agttcttcca ggagtcgacg gccgccgaca tccgcaagga ggagggccac
     8401 gcccaggtca tcttcgcggc caacaccatc tgccacatcc cctacctgga ctccatcttc
     8461 cggggagtgg acgagctgct cgcaccggac ggggtgttcg tcttcgagga cccctatctc
     8521 gccgacatcg tcgacctcgc ctccttcgac cagatctacg acgagcacta ctacttcttc
     8581 tccgtctcct ccgtgagcgc catggtcgag cggttcggct tcgaactggt cgacgtggaa
     8641 cggctctccg tgcacggcgg cgaggtccgc tacaccatcg cccgcgccgg acggcgcacc
     8701 cccgcgcccg cggtcgccga gctgctgggg caggaacgcg cgcgcgggct gtcggagctc
     8761 gccaccctcc agggcttcgt ggcccgtgtg gagcgggccc gggacgagct ggtcgcgctg
     8821 ctgcgcaggc tgcgcgacga aggccgcacg gtcgtcgggt acggggccac ggccaagagc
     8881 gccaccgtcg ccaactactg cggcatcggg cccgacctga tctccttcat ctccgacacc
     8941 accccgaaca agcagggacg gctgacaccg ggctcgcaca tcccggtgcg gtcccgggcc
     9001 gacttcgaga acccctaccc cgactacgcc ctgctgttcg cctggaacca cgccgaggag
     9061 atcatcgcca aggaacagca gttccgggcc tcgggcggca agtggatccg ctacgtgccg
     9121 gacgtccgcg tgctgtgagc gcgcccgcgc ccacagcacg cgaacacgcc ggccgaggaa
     9181 gggtgcccga tgcgggtcct gttcaccaca cacacagcga agtcccatct gttcgcacag
     9241 gtctcgctgg cctgggcact gcgggcggcc ggccacgagg tccacatggc cggccagccc
     9301 gacctcgccg acgacatcac ccgcaccggc ctgaccgccg tgacggccgg agccgcgctc
     9361 gacctggcgg cccagatgga gtcgtacgaa catgacgagc acgacgggtc cggcgacggc
     9421 acggtgcagg acccgggagc ctgggagggg accggcggcg cggacgacta ccgggcgatc
     9481 gccgagcggt acgagtactg gacggacatg accgagatcc gtccacagaa gctgtcgtac
     9541 gagtacatgc acggcgtctt caccgccatg accacccagg tgttccagca gtactccgca
     9601 cccgcgatga tcgacgacct ggtgcgccac gcccggtggt ggcggccgga cctggtcgtc
     9661 tgggacccgc tgaccttcgc gggtcccgtc gcggcccggg ccgtcggcgc ggcccacgtc
     9721 cggctcctgt tcggcctgga cctcatcggg cggatgcgcc gcccctacct cgacgcgctg
     9781 cgccggctgc cgccggcgca gcgcgaggac cccatggagg agtggctggg cgacaccgtg
     9841 cggcgctacg gcggggagtt cggcgaggac ctcgtcgtcg ggcagcgcac catcgacccc
     9901 ctcccgcccg ccctgcgctt cctggacggg ccggaccgcg tacccatgcg ctgcgcgccc
     9961 cacaacggca gctccgtcct cccggactgg ctgcgcgagc cgcaggagcg caggcgcgtc
    10021 tgcctcacgc tcggcgtctc gcaccgtgag ctgctcggcg ccgaccggct cccgctcggg
    10081 gaggtgctcg cggccctcgc cggtgtcgac gccgaggtgg tggccaccct gaacgcggcc
    10141 cagctcgcgt ccgtcaccga agttccggac aacgtccgcg tcgtggactt cgtacccctg
    10201 gagaccctgc tccccagctg ctccgcagtg atccaccacg ggggagcggg caccttcaac
    10261 accgcgctga gctgcggagt gccccagctg atcctgcccg acggggtgtg ggacaccgac
    10321 cacaaggccc gcctgctgga ggagcgcgga gccgggatcc gggtcgcgca gcccgagaag
    10381 gcggacgccg caacgctgca cggcatgatc acgcggctgc tggaggagcc ctccttcggc
    10441 cgggcggccg cccggctgcg cgacgagtcg agggacatgc ccgcgcccag cgccgtcgta
    10501 cccgtcctcg aagagctcgc cgccgggcga cgaccgcacc aacgacaggg agagtggcag
    10561 tgaaggacct atcgcgccgc ggattcatcg cgggcggcgt cgcggccgga ggcgccgcgg
    10621 cgctgaccgc cgccggcacg ggaacggccg cggcggacac gacggccgcc ggctgcttcc
    10681 cggcgccccc ggccaaggac atccgcccgg gcgacccccg ctacgcggag ctgacggcca
    10741 ggggttacaa cgggcggttc tccggccgcc cggagtccgt acgcctcgtc caccgcgccg
    10801 accaggtggt cgccgccgtg gacgacgccc tgcgcaccgg ccggcggatc gccgtccgca
    10861 gcggcggaca ctgcttcgag ggtttcgtcg acgacccggc cgtccaggtc gtcgtcgacg
    10921 tctccgagat gaagtccgtc cactacgacc cccgccacaa ggccttcgcc atcgagtccg
    10981 gcgcgacgct cggtgaggtc taccgcaccc tctacctcgg ctggggagtg accgtcccgg
    11041 cgggcgcctg ccccggcgtc ggcgccgggg gccacatcgc gggcggcggg tacggggggc
    11101 tgtcgcgcca ccacggcttc gtcgccgacc acctgtacgg cgtcgaggtc gtcgtggccg
    11161 accgccccgg ccgggcccgc ctggtcaccg ccacccgtga ccccgccgac ccccaccacg
    11221 acctgtggtg ggcccacacc ggcggcggag gcggcaactt cggcgtcgtc acccgctatc
    11281 tgatgcgctc tcccggcgcg cgcggcgacg acccgacgac cctgctgccc aagcccccgg
    11341 cgacgatccg ctccgtcacc atcggctggt cgtgggcgga catgaccgag gcggccttcg
    11401 tacggatcct gcgcaaccac ggcacctggc acgagcggga gtccgccgcg gactcccgct
    11461 acgcacccct cagcgcctgg ctgatcctca accaccgggc gaacgggcgg ttcaccctcg
    11521 tggccaacgt ggacggctca ctgccgcacg gcgcgcagct gctcgacgag tacgtcgcgg
    11581 cgatcaccgc cggcaccgga gtgcgccacg aggccgaaca ggccaccgcg ctgtggatga
    11641 agtccaccct gaccaccgac ccctacgccg gcggcgggta ccccttcaag tccaaggccg
    11701 cgctcctgcg caaggcctgg acggagaccc agatccggac cctgcaccgc tgtctgacca
    11761 gctccggcgg cgagcaccag ggctcggccg tgtacctgtc caccctaggc ggcaggatca
    11821 acacggtccc ggcgtccgcg acggcgatcc cgcaccgcga cagcctcttc agcgcctcct
    11881 acgagacctc ctggtggccc gggatctccg gcgacgagca actggcctgg gtgcgcgagc
    11941 tctaccggga cctgtacgcg gacaccggag gcgtccccgt gcccgacgcc gcgaacggcg
    12001 gggcctacat caactacccg gacgtcgacc tcgccgaccc ccggtggaac acctccggcg
    12061 tgccctggca caccttctac taccgggaca actacccccg gctccagcag gtcaaggccc
    12121 gctgggaccc ggcggacgtg ttccgccacg cgctgtccgt ccggccgccg ggccgctgac
    12181 gcgccggcgg cgcccgcggc cagcgctccc gcggcccctc agacgaggga ctccaggcgc
    12241 ccgacgagcg cggcggggga cggcatcgcc gccgcctcgt cgcgtacctc ggccgcggcc
    12301 gcccgcatcc cctcgtcctc cagcagggcc cggaactccg ccgtgccgac gactcccgcc
    12361 gacgtcccga tcgcgatgcc ccgctcgacg accgcgcgct cgttgtcctt ctggtccggg
    12421 ctgagcggca tcacgcactg gggcacgccc atggccatcg cgaccgccga cgtacccgac
    12481 ccgccgtggt ggatcagccc gtgacaggtc cgcagcagcg gacccagggc gagccagtcc
    12541 accgtcctca cgttcggcgg cagttcgccc agcagcgacg gatcaccgcc gccgagggtg
    12601 acgacgaact ccgcgtccgt gccggccgcc gaggcgacga gcggcgccag cacggcgagc
    12661 ccgccccaca ggccggcgat cgacccgagc gtgacggcga tcctgggccg tcgcggcggc
    12721 tccaggagcc agccgggcag ctcgccgttg ccgttgaagg gcacgtaccg gaacgggacg
    12781 tcgtcctccg cccgcacccg ctccggaagg agctccagca ggctcggcgg tatcgagttg
    12841 agccggaagc cgggcgccgg caccggtgcg acgtcgtgcc gcacgtagtg ctccttcatg
    12901 tgatcgcgca tcaggccggc gatgagcggc gcgctgtcgg ccggaccggt gaccaccgac
    12961 acggcgggca cgccgagcgc ccccgccacc agcggtcctg cgccctggag cggcgagtgg
    13021 acgatcaggt ccggcgacca gccgcgggcg acctccagca gccggtccac ggtgacgccc
    13081 gagaccctgg cgaagagcgc ggcgacgaac tcgtccccgc cgtcgacgct gaagtcgatc
    13141 tcctcgggcc ggaacaccgt cgcatagtcg agcccggggg tcacatcgac gacgttgacg
    13201 cccgccgcgg ccaccgcgcc gacgtcaccg ccctgggcga acagcacgtc gtgacctgcc
    13261 gcggtcagcg cgtgcgccag gggcaccgac gggaagatgt gccccagccc tggggagttg
    13321 acgaacagta cgcgcatggg gactcctcgc ctcatgaaag gggtggggtg ctggtgccac
    13381 gctccccccg cgtccttgaa ggctcacgga gccttgttga acacgccctt cgagcgtctt
    13441 tcgacacccg gctgccaggg tcggtgcccc cagcgagccg aaggactgcc ttgtcagatg
    13501 gagatcatcg ggaacgggtt cctcgcacga catctcgcac cgctctcggc cgggcatccc
    13561 ggagtgacgg tgctggccgc gggcgtgccc acgcatccgc tgcccgacgc cgagcaccgg
    13621 cgtgaggccg ccctcgtcga agacgcgatc cggcactgcc tgcgcaggga ccggatgctc
    13681 gtcttcttct ccaccgtcag catgtacggc ggtccgggag gccccggcga cgaggacggc
    13741 ccgcaggtcg cctccacccg ctacgggcag cacaagctcg acctcgaacg gctggtcaag
    13801 gcctccgggg tgcgccacct cgtcctgcgg ctcggctacg tactgggccc ggacgaaccc
    13861 ggcttccgcc ttctgacggc gctcgtcacc caggtcctgg ccggccgggt gcgcgtccag
    13921 cgcggagccc gccgggacat gatccacgtg gccgacttca ccaccgtggt ggacgccctg
    13981 ctccgtaccg gggtgtgcga cgagaccgtg aacgtcgcgt ccggggactg cgtcgaggtc
    14041 gccgacgtcg tgcgccacct cgaacagcgc ctcggggtca cggcccactg gcaggtcacc
    14101 gacgacagca tcgagcactg cccctcggta cggaaactgc ggcggctggt gcccgggctc
    14161 gaacggctgg gattcgggcc gggataccac cggtccgcca tcgaccgata tctggcggcg
    14221 acgcgtcccg cggacgtcat ccggagggaa aggacggaaa cgccatgacg gcgggagacc
    14281 tgaccgaacc gcgcacaccc gagggccacg cactgctgga ggtactcgac cggcacctgc
    14341 cggacctcgc ggccggcgcc gcggagcacg accgcaacgc cgccttcccg ctggacgcgg
    14401 tccgccgcat gggcgccgac ggcgtcctcg gcgcgaccgt gccacgggag ttcggcggac
    14461 tgggcgtcac cagcgtccac gacgtgtgcc tcgccgtgaa gcgcatcgcc gaggccgacg
    14521 ccgccgtcgc cctgtcgctg cacatgcagt tcagccgtgg gatcaccatg tcgtacgagc
    14581 gcgagcacgc agccggcacg gggcgcgccc tggccgagcg gctgctccgg ctcatgggca
    14641 ccgaacgggc cctgatcagc ggcgccctca aggacgccgg cgtcaccacc gagctggtgc
    14701 ccgcggacga cggcggctgg cggctcaccg gccgcaagat cctggtcagc atggccccgt
    14761 tcgccaccca cctcgtcgtc gcggcgcaga cccgccccgc ctcggggccc gcacggatcg
    14821 cctccgcgtt cctgcccgcc gacacccccg gcctgaaggc gccggacacc tgggacggca
    14881 tgggcatgcg ggcctccgcc agcaccgagg tcgtcttcga ggactgcccc gtccccgcgg
    14941 ccgacgtctt cctgcgcgga ccggtcggcg tacgcaacga cgccgcgatg gcgggccaga
    15001 ccgtcagctc catcggactg ctcggcgtgt acgccgggat cgcgcaggcg gcacgcgact
    15061 tcgccgtcgc cggcatcgcc cggcgcggcg gacagccggc ggccgccgtc cgcaccctgg
    15121 tggcggagct cgacgtgaag ctgtacacgc tccgcacggc gctcgcggcg gccctgacca
    15181 acgccgacca ccacgcgcac cgcacgacgg tcgaccccga cgagcgcggt cggctgatga
    15241 tggcgccctt ccagtacgcg aagctcgtcg tcaaccgcac cgcggccgac atcgtcgagg
    15301 acagcatgac cctcatgggc ggggcgtcct tcaccacgag ccaccccctg tcgcgccact
    15361 accgcgacgt ccgcgccggc tggttcatgc agcccttcac ctacgccgac gccgtcgacc
    15421 acctgagcgc gcacgcgctc ggcaccgacc tggagggcag cacgtcgtga gcggtacgag
    15481 gaacgggacc ggcggcggcg ccgaccggga gcagaggccg gcggacgacg ggcccgtgga
    15541 ggaacggccc gtcgacgccc tcgtgcggat gtcgaacctg gtgaccccca tggccctgcg
    15601 ggtcgcggcc accctgcgcc tggtggacca cctgcgccgg ggcgtcacca gccccgaggc
    15661 cctcgcccgg gcgaccggag cggacgccga cgccctgtcg cggctcatgc ggcacctggc
    15721 cgccgccggc gtgctggagg agaccgcacc gggccgctac gcgccgaccc gcctcggcga
    15781 cctgctcgcc gaggacgacc cgtcacggca gcgctcctgg ctcgacctgg accaggccgt
    15841 cggccgcgcg gacctgacct tcctcgacct gcgcgaggcc gtccgcaccg ggcggccgca
    15901 gtacgaggac cgctacggca aaccgttctg gacggacctg tcggaggacg cggaactcgg
    15961 agcgtccttc gacaccctga tgacgacccg ggaggacgcc gccttcgccg cgcccgtctg
    16021 cgcgtacgac tggagccggg cccggcacgt gctcgacgtg ggcggcgcac cgggcggact
    16081 gctcagcgcg atcgtgcggg ccgcgcccgg cgcgcgcggc accctgctgg acctgccggg
    16141 agcggcgcag cggacgcgcg agcgcatcgc cgcggccggt ctggacgacc gcatcgacgt
    16201 cgtcgccggc gacttcttcg acgaactgcc cgtctccgcc gacgccgtcg tgctgtcgtt
    16261 cgtcctcctc aactggtcgg acgcggacgc cctgcggatc ctggcgcgct gccgcgacgc
    16321 cctgcggccc ggaggccgga tcgtcctgct ggagcgggcc gaggcgccgt ccggcggcac
    16381 gcggacctcc gacctgtact tcagcgtgct cgacatgcgc atgctcgtgt tcctcggagg
    16441 ccgcgtccgc accgaccgcg aatgggccgc cctggccgac gccgcgggtc tgcgcatcgt
    16501 ctccaggtcc gggccgctgg tctcgccgag cgtgcccctg gactcctgcc tgtgggagct
    16561 ggccccgcac tgagcccgta cccgaccacc agcaccgccc atccacggaa ccaggggttc
    16621 caggagccga gagggatacc gaagtggcag aacgtatcgt cacgtcgaag gacgtgcagc
    16681 tgtggagcga ggacttcggc gaccccgccg accccaccgt gctgctggtg acgggcggga
    16741 acctcaccgc gatgagctgg cccaccgagt tcgtcgaacg gctcgtcgcc gacgggctgc
    16801 acgtgatccg ctacgaccac tggggggtgg gccgctccac cggctgggac ccggccgagc
    16861 gcccgtacag ctacctccgg ctggccgccg acgccgtcgc ggtgctcgac ggctgggacg
    16921 tcgaacgggc ccacttcgtc ggcatgtcga tgggcacggt cctgtgccag ctggtcgcgc
    16981 tcgaccaccc ggggaggatg ctcagcatgt cgatgatgct cggcggcgca ctcgacgtgg
    17041 acttccccgg caacatccgc cgcgccttcg ccggcgagcc gtccgccgac ggactgcccc
    17101 tgccccagga acgcttcctc gaggcgctcg ccgtcatgaa cgaggaagtg gacggcccgg
    17161 aggcggaact ggagcggcgg gtgcgccggt ggaagctgtt ctccggagac gagaccgcct
    17221 tcgacgaggc cgacttccgg cggtgggaac agcaggccat cgaccactcc ggcgccctca
    17281 ccgagcccca ggtgcactac gcggtgcagc cgccgccccg ggagcgcgcg cccgagctgc
    17341 gcgacgtacg ggtccccacc ctggtgatcc aggcgatgca ggacccgatc gcgcccccgc
    17401 cccacggacg ccacctcgcc ggtctgatcc cgggcgcgga actggtcgag atcgagggca
    17461 tgggccacgc gctgccgcgc tcggtgcacc cgccgctcgc cgaggccgtg ctgaagcacg
    17521 tgcgccgggt cggatgaccg gccgtccgcc tcagtcggcg agctcgaacc ggggctcctc
    17581 ggtccgggtg cgcttgacct cgtagaagcc cggaacaccg gccatcagca gcagaccgtc
    17641 ccacaaccgg ccggccgtct cccccgtggg cgcgggggag acgaccggac cgaagaagcc
    17701 gacccgttcg ccgcccggcc ggacgaccga caccaccggg gtgccgatgt cgccgccggc
    17761 cagcgcgacg gcctgcgcgt gcgaggaccg gacggccccg tcgtactccg tggaaccggc
    17821 gacttccgcg atctcctccg gcagcccggc atcggccagg gcccccgcca ggttccccca
    17881 gtcgccctgg aggtggaagc ggttgcccat cgcggtgaag aggtcaccga gcgcctgctg
    17941 gccgaaccgc tcctcgaccg cggcgcagac ccgcaccggc gcccacatgt agtcctccca
    18001 ctcgccctcg gggttgtcgt cccggtgctc gttgagcacc gacaggctca tcacccgcca
    18061 gtggacggtc accggccgca ccttggtgac ctccaccagc caccgcgagg tgatccacgt
    18121 gtacgggcag acggggtcga accagaagtc cacggtccgc tgttcggtca tcgatcggcg
    18181 ctcctcacac ggctctctct agcggcgcca gccgtccggc tccggccacg gctcgccgag
    18241 ctggcggtac gtgctctggt actccggcca gtcccggtgg tccctgatcc tgccgtcgac
    18301 gacgcgcagc aagtggatct gttccccgga gaagcggcgg ccggtcggcg cgatgccgac
    18361 catggggccg acctgacggc cgtagagcac caggtaggcc cgcacccagt cgccccgctc
    18421 ctcgatcctg acctcctcca gatgcgcttc ctcggagaag gtcttccgca cccaggctac
    18481 cgccatggcg aacgcgtcgg gcccttcacc gagcccgtgc tcgatcgtgg ccggattcag
    18541 atactccggg tggatgaact cgtggacgtc gtcggtcctg ccggtgttgt acgccgcgat
    18601 catccgccgc acggcttcga tgttccgact cactgggtgc ctccggctct cggtgtgctc
    18661 gttgccgacg agcatcccaa caccctgatc ggcagcggat cgacgttcgc tcgagccggc
    18721 cctccacggc ccctccacgt cccctccacg gccgctcgac ccccgaccgg gcacggccgc
    18781 cgccggtcca gacgctgttg agcgggctgc gagacccgac gcccacgttg gacgacgcca
    18841 catcgtcaga gcccgacgcc ggacctgaaa agaggcgtga gatgcaaccg aacgaccttg
    18901 atcccagcgg gagcggggtg gtcaccttca tcaacagatt caccgtgcac gcctcgcccg
    18961 aggagttcga gaaggccttc gccgagaccg gacggcacct ggccggccgg gacggattcc
    19021 tgcggtacac gctgcaccgc cacgccgagg acccgacccg ctgggtcaac atcgcacact
    19081 ggcgcgacgc gcgggccttc cgtgccgccg tgggcgcacc ctccttcccc cagcacgtcg
    19141 cccggcttcg ggaactgagc accagcgagc ccggtctgta cgtcccccgg cagtacgtgc
    19201 cggcggagcg ggcggcgacg gagggcctct gatggacgcc tccacgggcc gccgcgtcgt
    19261 catcaccggc atcggggtcg tcgccccggg agccgtgggg cgcaagccct tctgggacgc
    19321 cctgaccgcc gggcgcaccg ccaccaggag gatcaccttc ttcgaccccg gcccctaccg
    19381 ctcgcagatc gccgccgagg tcgacttcga cccgctgggc gagggactga ccccgcagca
    19441 ggtccggcgg atggaccggg ccgcgcagtt cgccgtggtg agcgcccgcg agggcgtcgc
    19501 cgacagcggg ctggaccccg cggggctcga ccccgcgcgc accggtgtcg ccatcggcag
    19561 cgccgtcggc tgcaccatga gcctggagga cgagtactcc gtcgtcagcg acggcggccg
    19621 ccactggaac gtggacgcct cctacgccgg acgccacctc ttcgactact tcgtgccgca
    19681 ctcgatcgcg gccgaggtcg cccgcgacgt cggcgccgaa ggacccgtgt cgctcatctc
    19741 gaccggctgc acctccggac tggactcggt cgggcacgcg gtggagctga tccgggaggg
    19801 cgcggtggac gtcatggtgg ccggcgccac cgacgccccg atctcgccca tcaccgtggc
    19861 ctgcttcgac gcgatcaagg cgaccacacc gcgcaacgac gaacccggcc tggcctcacg
    19921 gcccttcgac cggaccagga acggcttcgt cctcggcgag ggcgccgcgg tcttcgtcct
    19981 ggaggacgcc gagcacgccc gccggcgcgg cgcgtacgtg tacgccgaga tcagcggctt
    20041 cgcctcccgc tccaacgcct tccacatgac cggactgcgc ccggacggac gggagatggc
    20101 cgaggcgatc cgcgtggcga tgctgcgggc cggggtcgcc ccgggggaca tcgactacgt
    20161 caacgcgcac ggctcgggca ccctccagaa cgaccgccac gagacggcgg ccttcaagag
    20221 ggcgctgggc gaggacgcct accgggtgcc cgtcagcggc atcaaatcga tgatcggcca
    20281 ctcgctgggg gcgatcggct cgctggagat cgcggcctgc gccctcacca tcgagcacga
    20341 caccattccg cccaccgcca acctgcacga gccagacccc gaatgcgacc tggactacgt
    20401 gccgttgacc gcgcgccgac agcccgtgga caccgtattg accgtgggca gcggcttcgg
    20461 cggcttccag agcgccatgg tgctgcgcag cccggagagg gcggcgtcat gacctccacc
    20521 gctgtgatca cgggcatggg cgtgatcgcg ccgaccggcc tgggcgcgga gtcccactgg
    20581 agccgcacgc tggccggacg ggccgcgatc ggccggatca gccacttcga cgccgagcgc
    20641 tacccgagcc ggctggccgg cgagatcgcc ggcttcgatc cgcgcgaaca cggcatcccc
    20701 agccggctgc tgccgcagac cgaccacatg acccggctgt ccctggtcgc cgccgaatgg
    20761 gcgatcaagg acgccggggt ggacctcgcg gcgatgcccg agtacggcgt gggcgtggtc
    20821 acggccagtt cggccggcgg gttcgccttc ggccaccggg aactgcacaa cctctggagc
    20881 aagggaccgg agcacgtcag cgcctaccag tccttcgcct ggttctacgc cgtcaacacc
    20941 ggccagatct ccatccggca cggcctgcgc ggcccgggcg gcgtggtcgt caccgaacag
    21001 gccggcggcc tggacgccct ggccaaggcc cgccgccaac tgcgcgacgg cgtcccgatg
    21061 gtgatcgccg gcggcgtcga cggctccccc tcgccctggg gctgggtcgc ccagctggcc
    21121 ggcggccgca tcagcaccgc cgacgatccc gagcgggcgt acctgccctt cgaccaggac
    21181 gccgccggcc acgtaccggg cgagggcggc gcgctgttcg tcctggagac cccggagtcg
    21241 gcacgcgccc ggggcgtgcg gtcctggtac gcggagatcg ccggccaggc gtccaccttc
    21301 gacccggcgc ccggcagcgg ccgcccgtcc accctgcggc gggccgccga actcgccctc
    21361 gacgaggcgg gactggaacc gggcgacatc gacgtggtgt tcgccgacgc cgcgggcgtc
    21421 cccgacctgg accgcgccga ggcacaggcc gtccgcgagc tcttcggccc gcagggcgtc
    21481 cccgtgaccg cgcccaagac gatgaccgga cggctcggcg ccggcggggc ggcactggac
    21541 ctggcgacgg ccgtgctgtc catccgggac ggggtgatcc cgccgacggc caacgtgcgc
    21601 cgcccggtcg ccgagtacgg catcgacctg gtcagcgccc cccgccacgt accggtgtcc
    21661 gccgcgctcg tgctggcccg gggacacggc ggcttcaacg cggccgcggc cttgacccga
    21721 caacgatgag gagagacatg cccgcccaag acgaccgcca cgccctggtc accggtgcca
    21781 ccagcggcat cgggctcgcc atcaccaccc tgctgtgcga actcggccag cgcgtgttca
    21841 tctgcgcccg cgacgaggag aacgtcgcac tcaccgtcga acgcctccgc gagaaggggt
    21901 acgaggtcgc gggcctggcg tgcgacgtac gctccaccga acaggtcggc gccctcgtgc
    21961 gggccgccgt cgaccggtac gggcccgtgg acgtgctggt gaacaacgcc ggccgcagcg
    22021 ggggaggccc caccgcgcag atcaccgacg agctgtggct cgacgtcatc gacaccaacc
    22081 tcaacagcgt cctgcggatg acccgcgagg cgctcaccac cggcggcatg ctcgaacggg
    22141 gcacgggccg agtcatcaac atcgcctcga ccggcggcaa gcagggtgtg gtgctgggcg
    22201 ccccgtactc cgcgtccaag cacggcgtcg tcggcttcac caaggcgctg ggcctggaac
    22261 tggcccccac cggcatcacc gtcaacgcgg tctgcccggg ctacgtggag acgccgatgg
    22321 cccagcgggt caggcagggg tacgccgcgg tctgggacac cacggaagag gccgtgctgg
    22381 aacggttcga ggcgaagatc ccgctcggca ggtacaccac cccggaggag gtcgccggcc
    22441 tcgtcggcta cctcgtcacc gaccgggccg cacccgtcac ggcgcaggcg atcaacgtct
    22501 gcggcggact gggcaactac tgacggccgt ccgaggacca ggagacccgc accatgacga
    22561 acaaccaccg agccgagcac cggatcacgg tgcaggcacc cgcccgcacc gtctacggcc
    22621 tgatcgcgga cgtcgaatcg tggccgcggg tcttcccccc gaccgtgcac gtggacgtcc
    22681 tcgaccggac cgccggcgag gagcgcatcc gcctctgggc gaccgccaac gacgccgtca
    22741 agacgtggac ctcgcgccgc gtcctcgacc ccggcggact gcgggtgggc ttccgccagg
    22801 aggtgtccca gccgcccgtc gccgccatgg gcggcgaatg gaccgtcgaa ccgctgtcgg
    22861 acaccgtatc gctggtccgc ctgacccacg acttccgggc cgtcgacgac gatccggagg
    22921 gcgtggagtg gatcacccgc gccatcgacc gcaacagcga cgcggaactg gacgcgctcc
    22981 ggcgggccgc cgagcaggcc tccggcaccg gcgccgacga cctgtcgctc gagttcgacg
    23041 acgtggtgga ggtggccggc gaccccgccg acgtgtacga cttcctctac gacgcccggc
    23101 ggtggcagga gcggctgccc cacgtgaacc gggtcgagct ggaggagagc accccgaacc
    23161 tccaactgct ggagatggac acgctcaccc cgaacggcgc cgtccacacc acgaagtcgg
    23221 tccgggtctg cttcccctcg gccgccatcg tctacaagca gctcaggaca cccgccctga
    23281 tgaccgtcca caacggcctc tggcggatcg cgaagagcac ctccgggtgc accgtcacct
    23341 cgacgcacac ggtcgtcctc agccgggacg ccgtcgtccc cgtcctcggc gagggcgcca
    23401 cggtcgggga cgcgcgcacc ttcgtccgcg acgcgctcgg ccgcaacagc acggcgacga
    23461 tgctgctcgc caaggagcac gccgagcgag cggcacggga gcgctgatgc gcgtcctgtt
    23521 caccaccttc ggcgcgcgca accacgtcca cgcccaggtc gcgctcgcct gggcgctgcg
    23581 ggccgccggg cacgaggtct gcgtggccag ccaccccgac ctcgccgagg tcatcgcccg
    23641 caccggactg accgccgtcc cggtcggccg cgagctgggc gaggaacgac tgatggagga
    23701 gctgcgggaa cgcgaggacg cctcccgcga gacctacgac gaggacgccc cggacgccca
    23761 gctgctgctg gcgatggacg agctgcgccc ggagaagctg acgtacgacc acatgcacgg
    23821 cgtgttcacc gcgatgacct cggccgtctt ccagaactac tcgtcggccg agatgatcga
    23881 cgacctggtc ggattcgccc gcggctggca tcccgacctg gtgatctggg atccgctgac
    23941 cttcgccgga gccgtcgccg cccgggtcac cggggcggcc cacgcccggc tgatgttcgg
    24001 gctggacctg gtcgggcgca tgcgcgagag ctatctggcg caggtgcgcc gacggcccgc
    24061 cgcgctgcgc gaggatcccc tgcgggagtg gctgggcacg gtgatggagc gctacggcgg
    24121 agagttcacc gaggacctgg tgaccggcca gtggaccgtc gaccccgtgc cgacctccct
    24181 gcggctgccg gcggacctgc cctacgtacc cgtgcgctgc gtcgcctaca acggcagggg
    24241 cagcgtcccg gactggctgc gcgaggcgcc ccggcgcccc cgggtgtgcc tgacgctggg
    24301 cgtctcccac cgcgaggtga tgggcggcga ccaggcgtcc gtcggcgagc tgatcgaggc
    24361 ggtggccgga ctggacgtgg aggtggtcgc caccctggac gcccgccagc tgcgcgaggt
    24421 cggcagcctt ccgcccaacg tccgcgccgt cgacttcgtc ccgatggacg tgctgctgcc
    24481 gacctgctcg gcgctcgtca gccacggcgg gtccggcacg gtgcacgcgg cgttcctgta
    24541 cggcgtcccg cagatcctcg tgccgggcac catgtgggac aacgcgatcc gcgcggacct
    24601 cgtgcagcgg tcgggcgccg gactgcgcct ggacgcgcag accctgaccg ccgccgccct
    24661 gcgcgacgcg ctcacccgtg tcctgaccga gccgtccttc acggccggcg ccgagcggct
    24721 gcgccgggag accctcgcca ccccgtcccc ccgggacgtc gtcccgctgc tggagtcgct
    24781 caccgccgaa caccgcgacg accttgtgag gaaccatgtc tgacgcagca cccctgcccc
    24841 cggtcacggc tccgcccccg gccccgcggt cggtcgtggt caccggaggc ggctccggca
    24901 tcggcagggc gatcgcccac gccttcgccg acgagggcgc ggccgtcctc gtcgtcggcc
    24961 gcaccgccgc cgacctcgcc ggcacggcga aggggtacga cacgatcagg acgctcgccg
    25021 tcgacctcac cggggccgat gcgccccggg aggtcgtgga gaccgcggtg cgcgaactgg
    25081 gcgggatcga cgtcctggtg aacaacgccg cggccctggg ccaccgcgcc ctcgccgacg
    25141 tcgaccccga gcaggtggcc gcccagctcg gcaccaacct ggcggtgccc gtgctgctca
    25201 cccgggccgc gctcgacgcc ctcgccgccg acggcggcgg caccgtggtc aacatcggct
    25261 cgtccggtgc gcgcggatcc agggcctggc cgggcaacag cgtgtacggc gccgccaagg
    25321 ccgccctgga cttcctcacc cgcagctggg cggtcgaact cgcgccgcgc ggcatccggg
    25381 ccgtcggcgt cgcgcccggg ctggtcgatt ccggcttcgc ggagcgggcg ggcatgtcgc
    25441 ccgaacagta cgacggcatg ctccaccacg tgggcgcgct gacgccccag ggccgtgtcg
    25501 gcacccccca ggagatcgcc tggtgggtca cgcacctcac ccggcccgag gccagccacc
    25561 tgaccggcgc cgtactgccg gtcgacggcg ggctctccct gacatgaacc ggtacgaccc
    25621 ccacagcggt acgggaccac agcaggcccc cggagaggcg gagttcagca catggtgacc
    25681 atgaacgaga gcgaactggg ccgtgtgctg ctcacgcacc gcggcgtcca gtggatcatc
    25741 ggcacgaagg acgacccgta cgccctgctc gtgcgggccg ccggcgacga cccgcaccgg
    25801 ctcggcgaac tgatccggga acggggcccg ctgtaccgga gcagcgccga ggcctgggtg
    25861 acggcgcacc acgaggtcgc cgcggccgcg ctcgccgacc cgcggctgag cgtccggcac
    25921 cccgacgcgg acgcacccgc cgcgcaggac ggaggggagc agcgcgagcc catgccctgg
    25981 gaagtgcccg cactgcgcga gatcctcccc ttcggcgggg ccttcctgac cgcgggccgc
    26041 gccgactgcg agcgcgtggg cgagctgctc gaacccctgc tcggcgcgaa ggccctggaa
    26101 cgccggcggc ccgtcgccga gcaggcgctg cgccgcgccc tcgccgaagc gggcagcggc
    26161 ttcgacctcc gcacggaggt ggccgacccg ttcgccgccg ggatcgtgcg ggagctgctc
    26221 ggcgtaccgg aggaggacca cgaccgcttc gcggcgctgt gccggggcgc cgcgggcctc
    26281 ctggacgcca cggtgtgctc gccgcacctg cgcacggcac gcgagctgat cgcttccgtc
    26341 gagggcatgc gctccctgct cgccggagtg atcgcgcagc ggcgcgagaa gcccggggac
    26401 gacctcgtca gcgccctgct ggcggcgacc cacgaggacg aggtgcggtc ggtgtgcaca
    26461 ctgctggccc tcgtcgggac cgagctgtcc gcgaccctgt tctgcgacgc ggtggcggag
    26521 ctgctcgacc accccgcgca gtggcgggcg ctgtgcgagg accccggtct cgctccggcg
    26581 gtcgtcgagg agacgctgcg ccacgccccg cccgtgcggc tcgtcccgct gtacgcgctc
    26641 gaggacctcg aactggccgg gacgcccgtc ccggccggcg gccaggtcgt cgtggcggtc
    26701 gaggcggccg gccgggactc tgccgtgcac ccggagccgg ccgccttcga cccggcccgg
    26761 gaacgggccg cggagcccct ggcgttcgcc gagggcctgc ccacgtcgct gccggccccg
    26821 acggcgcggt tcctcgcgga ggccgggctc cgcgcgctcg cggccgaggt cccgggcctg
    26881 cgtccggtcg ggcccgtcct gcggcgcctg cgctccggtg tcaccggagc ggtgatcgag
    26941 atgcccgtcg cccgctagct gattctcacg gtgcgtgacg atccctttgg tcgtgcgact
    27001 tgtacgggtc gtagtagaga tactatcttt gatctaacag gtctgatcga aaggtagggg
    27061 cctatggcgg agttaagtga tctgcgcgag gcgaaccggg ctgcgggagc accggacggc
    27121 tcggcaggcg aacgagtgat cgacatccgc ggactgcgta tgcggtacgg gtccaaagac
    27181 gtgctgaacg gggtcgactt cagtgtccgc cggggtgagg tgctcgctct gctcgggccg
    27241 aacggcgccg ggaagacgac gaccatcgag atcatggagg ggttccggac gcgctcggcg
    27301 ggcgaggtca gcgtgctcgg cgtcgatccg gccaagggcg acgaggagtg gcgcgccagg
    27361 ctgggcgtcg tactccagtc gtggcgcgac cacggcaagt ggaaggtccg ggagctgctg
    27421 gcccagctgg gggacttcta ccggccctac tccacgcccg agcggccgcg tccgcgcgac
    27481 gtggacgagc tgatctccat ggtcagcctg gaggagcagg cggaccagaa gatcgggtcc
    27541 ctgtcgggcg gccagcgccg ccggctcgac gtcgcgatcg gcatcgtggg ccgcccggag
    27601 gtgctgttcc tggacgagcc caccgtcggg ttcgacccca aggcgcgccg cgacttccac
    27661 gacgtggtgc accggctctc cgacctggag gacaccacga tcctgctcac cacgcacgac
    27721 ctggacgagg ccgagaagct gtccgaccgc atcctgatcc tcgccggggg ccagatcgtc
    27781 gcggacggca gcgccgacca gctcgcccgg cagacgtcgg gcaaggcgga ggtccgctgg
    27841 agcctgagcg gcgaacagtt cgtccacgcc acgcccgacg ccagcacgtt cgtccacgag
    27901 ctgttcaagc agcacggcga ccgggtccgc gacctggagg tgcgccgggc cagcctggag
    27961 gacacgtaca tgaccatggt ccgccagcac gaggccggcc ggtccgaaga ggcgatcgcc
    28021 gcgttccggg aggcaggccg atgaatccca ccctgtacgc cgtgcgactc ggtctgcgcc
    28081 gcggctggac cgagttcagg cagagcgtga cgtcgccggg cgacatcatc tactacctct
    28141 tcctcggggg cgtcttcctc ggggtgctgt tcttcatgcg gaactcgacc gtggagggca
    28201 ccgacctgtc gctggcgacg ctgaccatgc cgagcatgat cggcggcctg cttgccttcc
    28261 aggccctggg cggagcggcg ttcgcgctgg cggccgagcg ggaggacggc acgctgctgc
    28321 gggccaggac cgtcccgcag gggctcgtcg gctacatcgc cggccgcgtg ctgggcatcg
    28381 cgctgagcac cctgctcacc ctggtcatca tcctggtgcc cagcgtgttc ctcttcgacg
    28441 acctgatgac cggggacctc gccaagtggc tgaacctggt gtgggtgctg gccctcggac
    28501 tcctcgccac cctgccgatc ggcctgatca tcggcgccat ggtgaagaac ccgcgcggcg
    28561 ccaacacgtg ggggatcttc ccgacgatgg gcctgatggc gatctcgggt attttctacc
    28621 cgatcacctc gctcgcgggc tggctccagg gcattgcgca gctgttcccc gtgtactggg
    28681 tgggcctggg cacccgtgcc gcgctgctgc ccgacgcggc ggtcgcggtc gagctcggcg
    28741 actcctggcg caggcccatg accgcggtcg tgctgctcgc ctgggccgtc gtcgcgctgg
    28801 tgatcgcacc gagggtcctg ggccgtacgg tgcgcggcga gacgggttcg aaggtcgagg
    28861 cccgacaaca ggaggcattg aagcgcgttg ggtgacaagg aaaccggcgg caagcgcgcg
    28921 tcggcccgcc ggggcacgtc ggcggcggag ccggagaccg gggcggtggc cccgcggtcc
    28981 ggctccggca ccgacacgcc cgcggcgggc tggcgttcga ccggcgagca gggccgtccg
    29041 cgcggcggcg cagcgaacga gacggtgcac aaccgcatcg ccgtgctgcg ggtcgagcgc
    29101 gccatcacgc gcagacagct cgccgacgcc ctcggggtgc actaccagac ggtgggctac
    29161 ctggagcgcg gcgagtacag ccccagcctg cacctcgccc tgaggatcgc ggagtacttc
    29221 gaggtaccgg tcgaggtgat cttctcgacc accccgttcc cccggatcgg gagcactccg
    29281 cccgcgtagg cggcagcaca ccgcggccgt cggggcacag acaccccgac ggccgcggcg
    29341 caccggaccc gttctagcgc gaccggtgtt cggcggtgag ccgctccagg accgggacga
    29401 catcggcggg cgacggcgtg gcgaggacct cccggcggag ccggtcggcg ccggcacgga
    29461 acgacggctc ctgcagcacc cggaccagcg cggcgcgcag cccctgcggc gtcagcgcct
    29521 ccggatcgat gcacagcccg gcgcccgcgt cgcgcacccg gtgcgccttg gggacgttgc
    29581 accacatctt ggccggcacg atcacctggg gcacgccgtg cgccagcgcg gtctggaggg
    29641 tgcccgaacc cccgtggtgc acgatcgccg cgctggtcgg cagcagcgcg tccagcggtg
    29701 cgaagtcgac gacccgcacg ttgtccggta cgcgccggcc cggatcgagc tggtccgcgg
    29761 tgaacgtcgc gaccacgtcg acgtccaggt ccgccaccgc ctccagcagg tcgccgaccg
    29821 acgtccggtc ggcgccgacc acctcgcgga acgacctgcc gagggtcagg cagacacggg
    29881 gccggcgggg cggcggctcc cgcagccagt ccgggacctg cgcctcgccg ttgtacggta
    29941 cgtagcgcac cggcacggac ggcaggtcga ccggcagccg cagcgacggc ggaacgggat
    30001 cgatggtcca ctgccccacg accaggtcct cggtgaactc ccggccgtac cgccgcagga
    30061 tccggtccat ccactcctcc agcggatcct cccgcagcgc cggcggcagt ccggccagcc
    30121 cccgcaggta gtgctggcgc atcagcccga ccaggtccag gccgaacatc agccgcgcgt
    30181 gcgccgcgcc gctgatccgc gccgcgagcg cgccggggta gtacatggtg tcccagacga
    30241 ccaggtcggg ccgccaggaa cgggcgaagt cgatcagctc cccggtggtg tcgtccggca
    30301 gggtgttctg gtagacgaac gaggtccacg cggtcagtac cccgtggaca tagggaaggg
    30361 tcagcttctc cggccgcgtc tcgctgatgt cgaggacgtc cagccaggct tcgtcacgta
    30421 tctcgtcggg ctcgtcggtg tactccggat tcatcgtggc cgcgacgtcg aggaccccgc
    30481 cgaccgcgac cgcggtcagg ccggcgttgt tgatgtcctc gaccacgtcc ggccgggtgg
    30541 cgacacggac ctcgtgtccc gcggcccgca tcgcccacgc caggggtacc tgggtgtgga
    30601 cgtgggtgct cgccgggaac ggcgtgaaca gcactcgcat gggaggtcac cctgccggtg
    30661 cccgttcgca cggcactcga ggattcccgc agccgcgcac gagcccgcgt cgacgggcct
    30721 ccagcgaact tcgaagccca ccggcgagtc tcggccccgg gcaacggagg tccgacagga
    30781 cggccgccac cgaagcggga gaagacgatg gccacagctg acaaggaagt cgacgtactg
    30841 gtagtgggcg cgggcctggg aggcctgtcc acgacgatgt tcctcgcccg cctgggcgtg
    30901 ccggtgctca tggccgagaa gcatccgacg acgtcgatcc accccagagc gatcggccag
    30961 aacccgcgca ccatggagct gctgcggctc ggcgggatcg ccgagcaggt gcaggacgcc
    31021 accgaccacc gcggtgccaa gggccacttc acgacccggg tcgccgagac cgtacggggc
    31081 gaggtgctcg gcaccttcga agagggcttc gacaacctcg tcgccacgac cgcgccctgt
    31141 tcccccatgg cgtgggcgct ggcctggcag gaccagctgg agcccctgat gctggaccgg
    31201 gcccgccggg acggggcgca gatccggttc gccgccgcgc tcgtctccta cgaacaggac
    31261 gcggacgggg tgagcgcgct gctccgcgac cgcgagagcg gcgcggagac caccgtacgg
    31321 gcgcgctacc tggtggccgc ggacggcgac cgcagcccca tcagggaagg gctcggcatc
    31381 gcccgccggg gccacggctc gctgtcccac gtggtcggca tgatcttcga agccgacctg
    31441 tccggggtgc tcacctcgga cgcgtccggg ctgtactacc tgcgcaaccc cgccttcagc
    31501 ggcatcttca tcggcagcga ccgacccgag cggcacacct tcctggtcga gtacgacccc
    31561 gaacgcggag agtccgccga ggacttcact cccgaccgct gcctcgaact gatccgcacc
    31621 ggcctggacg caccggacct ggagcccaag gtgctggacg tccagcgctg ggagatggcg
    31681 gcccgcatcg ccgaacgctg gcgcgccgga agggtgttcc tggtcggcga ctcggcgaag
    31741 gtcgtgcccc ccaccggcgg gctcggcggc aacacggcca tcggcgacgg gtacgacctg
    31801 gcttggaagc tgtccgccgt actcaccggc caggccggcc ccggcctgct ggacagctac
    31861 gagcccgagc gcggcctcgt ggcccggctc gtgatggacg agtccatggc cctctacgct
    31921 tcccggctcg ccccgcacct gcaggaccgg atggcggagc ccgtcggcta tgccgaggtg
    31981 atcctcggct tccgctaccg ctcggacgcc gtcctcatcg acgacgacga ccccgcccgg
    32041 gtcgagtccc cggcccggcc caccggaagg cccggcttcc ggatgccgca cgtgtgggtg
    32101 ctcagggcgg gcgagcggat ctccaccgtg gacctcttcg gttccggctg gctgctcatg
    32161 accggtgcgg acggcgccgg ctggaccggc tgggcccgca gcgcgagcag ggaactcggc
    32221 gtccccgtcg aggtccacgg tccggccacc ggtctcgagg accccgacgg cgaactcgca
    32281 gaacggttcg gcatcggcac cggcggcgcc agcctcgtcc ggcccgacgg catcgtcgca
    32341 tggcgcaccg ccacccggcc ggacgacccc gccgccgccc tgcgcgacgc cctcacccgg
    32401 gtcctgtccc gctgaacggg accaccccgt accccaccac cacgacgaag gagcgaacac
    32461 gccatgacgg cccgaagcgc cccggtcacg gccgacgtcc tcaccgacga ggcccgccgc
    32521 cattaccagg agaacggttt cgtccgcatt cccgaagtcc tcaccccctc cgaggtcgag
    32581 cggttcaggg ccgcctccga ggaagtggtc gcccagcacg ggccggagat ctggggcgcc
    32641 ggcgaggacg aggtgcaggt gcacttcgtc gcccaggcct ggctcaagca cgaggcgctg
    32701 cgcgacctcg cgctgcaccc ggcgatcacc ggcatggcca agcggctcgc cggcggcccc
    32761 ttgcgcctct acagcaccga catcctcctc aagtccggcc gggagaccct gaacacgctg
    32821 cccacgctcg tccacgacga cgagacgggc ctcccgctgc acggcatcga ccggacgctc
    32881 acggcgtggg tcgcgctggt cgacgtaccg gccgagagcg gttgcctcag ctacgtgccc
    32941 gggtcccacc tgcgcgacgc cgcccaccgg caggtccaca tgaccagctt cgccgagtac
    33001 cggcccatcg ccgacatctg gccggactac gactggcagc cgcggatcac cgtgccgctg
    33061 aaggccggtg acgtcgcctt ccaccactgc cgcaccgtcc acatggccgg ggcgaacctg
    33121 accgacaacc cccggatggg ccacggcatc gtctacatgg acgacggcag cacctactgg
    33181 cccggcaccg aggacgccca catctcccac atggcccccg gggacccgct ggacaacgag
    33241 aagttccccc tcatctagag gagaccgtcg aaggtgagcg tcatgcacgg cacatggaac
    33301 cgcacggaca tcggagagct gggcagacgg ctccagcgcg cccacgggga ggtgtggctg
    33361 caccaggtga agggcgatcc gtacgccgac ctcctgcgcg gccacgccga ggacccccgt
    33421 ccgggccagg agcggatccg cgcgctcggc ccgctgtggc gcagcaccac gggcgcctgg
    33481 gtgacggcgg accaccggct cgccggggaa ctcctgggcg cggggtggcc gcaccgcccc
    33541 ctggcggacg acgaggccca cgtaccggtg gacgacgccg ggctcggcgg ggacgccgcg
    33601 cactacgagc ggctgcacgg gtacgcgcgg gacgccgtgc ccccggccgc cgtgcaggcg
    33661 gtgtccgagc gggtggtcgg cgccctggcc gcggacttcg acctggtcac cgacctcgcg
    33721 gaggccgttc ccacgaacct gctcgccgcg accctcgggc cggccggcgc ggaccgccgg
    33781 gaactggccc gggcctgcac cgccgccggg gtcgtcctcg acggcctgct gtgcccgcag
    33841 cggctggacg tcacccggcg ggcggtggcc gccgtcggcc ggctgcgcga gctcctcgcc
    33901 gaccccgccg ccgaccccga agccggaccg ggggccggcc cgcacgaggc cgcggtcctg
    33961 ctggccaccg ccggggtgcg caccgcggcg agcctgatcg ccggctccgt gctggcggtg
    34021 gcggaccacc ccgaggagtg gtcgcgcgtc gccgaagacc cagggcacgc cgccctcgtc
    34081 gtggccgagg tcctgcgcca cgaccccccg gtacgtatcc atccggcggt cgccctcgcc
    34141 gacgtcgaat tcgccggaca gcacgtgcgg gcgggcgagc gcgtggtggt gctcgtcgcc
    34201 gcggcgaacc gcgaccccga agtcttcgac gatcccgacc ggttcgtcac cggccgcccg
    34261 gtcgaggcac tggtcccggc cctccaccac cgggtgaccc tgccgttcgc ccgcgcccag
    34321 gccgaagcgg tcctgcgcgc actggtggcc gcccgcccgc gcccgcgccg ctcggccggc
    34381 cacctgcgca gccgccgctc acccgtcacg ggacacctgc tcggctgccc gctcaccacc
    34441 ggctgaccgg cgcccacaga aaggaacccc gcgatgagag tcctgttcac gtcgatcgag
    34501 ggcaaccact tccagcagat ggtcccgctg gcctgggccc tgcgcaccgc gggccacgag
    34561 gtgcgggcgg cctgcaacga aagcctcgtc gacaccgtca cccagaccgg cctgaccgcc
    34621 gtgccgatcc agtcgcccac cctctgggag cagctcgacg gcttccagaa ggaggcgatc
    34681 tccctcttca acgagatcgg caccagcaag caggacccct ccaaagcgac ctgggaggac
    34741 cacctctcct acgagaacat ggtcgtcccc gcgctctacc agccgctcaa caacgacgcg
    34801 cagatcgacc agctcgtcgc ggccgcccgc agctggcagc ccgacctggt cgtgtgggag
    34861 agcttctcga tcgccggggc cgtcgtcgcg gtcgcgaccg gcgccgccca cgcccgcctg
    34921 gtgtccgggc ccgagctcgc cctccagatg gtcacccgcg gacacttcgt acgccaccgc
    34981 gaccggcagc ccgagccgct gcgcgaggac ccgacggccg agtggctcga ctggaccctc
    35041 gaacgcctcg gcagcgaccg gcggttcgac gagaccatgc tgacgggcca gtgggtcgtc
    35101 gacacccggc ccgcgagcct gcgccagcag ctcgacctgc cgaccgtccc gatgcgctac
    35161 gtcccctaca acgggcgctg cgtggtgccc ggctggctca acgaaccggt ggagcgacgc
    35221 cgggtgtgca tcaccctcgg cacgtccatc accagcgagg agtccgagcg gttccggctg
    35281 ggcgagaccc tcgcggccct cttcaggagc ctggccggac tcgacgtcga gatcatcgcc
    35341 gccctcgacc cggcccagcg cggcgccctg cccgacctgc cggacaacat ccgcaccacc
    35401 gacttcgtcc cgctcaacga actggcgccg tcgtgctcgg tcatcgtgca ccacgccggc
    35461 taccagacca aggccaccgc ggacctgcac ggcgttcccc aggtcgtcat cgtcggctac
    35521 gagtgggtga gcgaggacat gggcgaggaa tacgagaagt ccggcaccac cctggccgtc
    35581 tccgcccgcg acctgaccgc cgaggtgctc cgcgagaaga tcctgcggct gctcgacgag
    35641 ccctcctaca ccgaacgggc cggcgcgctc cgtgacgaga tccgcgccat gccgacgccc
    35701 aacgaggtcg tgccggtcct cgaggagatg accagggagc accggcgccg cggatgaccg
    35761 gtccaccggc ccggcggccg gtggaccagt gctcctcgtg cgctcctcga gaccggtccc
    35821 gcagattcga tgccatgccg aatccgtggg atctccccga tgaactgccc accgaccttc
    35881 ccgtctcccg ctgcgaactg cccgacggcc gcgtgctgtc ggcggttcag gaagcggagg
    35941 cgcacaccct ctgggaggag atcagcagcg ccgcccccta ccgcaaggcg gccgagggcc
    36001 tccgccccgg cgaggccgtc atcgacgtcg gcgcccacat cgggctggcg tccctgctct
    36061 tcggcgggct ggcccccgag agccgtgtgc tcgccttcga acccgccccg aaggcctaca
    36121 cctgtctgga ggacaacctc gcccgcctcc tgccgggggc gaccgcgttc cggcaggcgc
    36181 tgggggccgc gtcgggtacg tccgaactga cctaccggcc ctacgtggcc tccgcctcga
    36241 ccctgtacga cgacgccgag gacgacgccc gcaacctcga agcgcacctc gacaacatcg
    36301 gcgccgacga gcggaccagg gaggtcgtgc ggcgcacctt caacgtgagc cagcgggtca
    36361 cggtcgaggt gaccacgctc gcctccgtga tggcggagca cgacgtcgac cgggtgggcc
    36421 tgctcaagat cgacgtcgaa cgcggtgaac tcgacgtcct cgacggcatc gacccggcct
    36481 gctggccccg catccggcgg gtcctcctcg aggtccacga catcgacggc cggctcggcc
    36541 gggtcgtctc ccggctgtcc ggactcggtt tccacgccac ggtctcccag tggggggtct
    36601 acgtcggcgg cagcgtccac ctggtgctgg cggagcggga ctgacatgcc gaggaggaag
    36661 ggccgatgag cgacggcgct ccgcgtccgt ccggatcggg ggcgacggcg gaccgcgccc
    36721 tcgcccccga tctcgcccgg ggcctgatgc tgctgatcgt cgccctggtg cacgcgcaca
    36781 tgttcgtcag tgggagcgcc gccgtgatcc gggggtatcc gccggtcgcc ggctcgcccg
    36841 cggacgcagc cacggcgggg gtgctcacgg tgctggccga cagccgcagc ttccccatgt
    36901 tcgccctgct gttcggctac ggcacgggcc ggatcctcgc acgcgagagg gaacggggac
    36961 gggacggacc cggtgcgcgc gcggtgctgc ggcgccgcgc ccgcctgctg ctgctgttcg
    37021 gggccgtcca cgcgctgctg ctgttcgccg gggacgtact gggcgcctac ggactgctcg
    37081 ccctggtcgc cgtcggcctg accggcgccc gtgaccgcat cctgttcacg gtggcgggcg
    37141 ccggtgtcgc cgtggggacg gtgctgtacg cgagcatgct ggccgcgggc gtctccggcg
    37201 acccggacga caccgcggcg gcgatgttcc tcgccgccga cccggtctcc gacgcggcgt
    37261 accgcatcgg cacctgggtg gtcaccacac cgctgttcgc cgtcatgtcg ctcggcccgt
    37321 tcctcatcgg tgcgcacgcc gcccggcagc gggtcctgga ggagccgggc cgccaccggg
    37381 tcctgctgcg ccgggtggcg gtgacgggca ccgccctgag cgtcgccgga ggcctaccgc
    37441 tggcgctggt cacctccggg gtgtggacca ccgcaccctc cgacgtggcc tgggggctca
    37501 gcgcgctgca cgtgctgacg gggtacgcgg gaggctgcgg cctcgccgcg gcggtggccc
    37561 tgctcgcgct gcggctggag ggccggcgga gcagggccgt gaccgccgtc gccgcgtgcg
    37621 gccggcggtc gatgagcgcc tacgtctggc agtcggtcgt ctggctcgtg ctgttcgccc
    37681 cgtacacctt cgggctcggc gaccgcgtgg gcgtcctcgg ctccgcgctc gtcgccctgg
    37741 gcgcgtgggg cgccggtgtg ctgctcgccg acctgctgcg ccgaaggggg cggcgcgggc
    37801 ccgccgaggc gctgctggcc agggtcaccc ggcgggcccc tccggcggca gctgccgctc
    37861 cggagcgcga ggacgcggta cgcgaggtca acgggccacc gtcgccgtga cgtagcgcac
    37921 cggcgtctcg atcgacaggg gtccgccgtc gtggcgcatc tcgtccagcg ccccggtgag
    37981 ccggacccgc agccgctccc ggtcgtcgtc gggcaggtgc tcccacagca ggcgcatgcc
    38041 ctgggtgtgg gaccacgcca cccacgcctc gccggacggg gccacgaggt cgaccggttc
    38101 gtcggtgatc tccacctcgt ggaaccccgc ggactccagg gcccggcgca ggtccgcctc
    38161 ctgcgccagc cagctgttga agcgcttctg gagttcctcc ggccgccact gcggcggcag
    38221 gttctccagg agcgagcgcg ggatgagctc ggtgaagacg ggcgggagga aggggaaggc
    38281 gtcgtcgtcg aacaccgggc tcgtgaaggc gatgcgcccg ccgtcggcga gcagttcggc
    38341 gtagcgcggc agggcggccc gggcctccgg gaagaagatc aggctgtagc tgccggtgac
    38401 gacgtcgaag gagcgggccg gcagatcggg gaactccccg tccatcacgc gcagttcgac
    38461 gttggcgatg cccaggtcgg ccgcctcctt tcgcgcctcc tcgatcatgg ccggcgcgat
    38521 gtcgatgccg aggacgcggc cctggtcgcc gacgagcgcg gcggcgtgga agaggcacgc
    38581 cccccgcccg cagccgacgt ccagcacgcg ctgcccgggc tgcggcgcgg cccgttcgac
    38641 gaggcgccgc cccatggggg tgaagaaggt gacccccatc cggtcgtagg acccggcggc
    38701 gcggtcgaag gcggccgtga catgggcctt gtaggttgtc ttgtccatgt gcgtcgctcc
    38761 caggaatggt cggcgtgtcc ggcccaccat cgtccggccg gcacctgcga aagcactcga
    38821 gggcagatgg accgggcccg gtcgcggtcc gggccggggc tcctggcgtc cagccgtcgt
    38881 tgaggcgcgt acgagacccc gcggccatca tcgtcaccag cacgagggcc cggtggagac
    38941 ccccgatcct ggcacgccgg acacgggacc aaggcgctga cgggccacgg accacagacc
    39001 gcacatcact gcattgaatg ggagtccggc atggtttcct ccatggagtc gcggaaactc
    39061 tccgtcgagg gcgcaatcga attcaccccg cgcgtgttcg acgacgagcg tggcatattc
    39121 ctgtcgccct accaggagtc ggcgttctcc gacgccaccg gcgggcacac gctcttccgc
    39181 gtggcccaga ccaatcacag taggtcacga aagggcgtgg tgcgcgggct gcactacacc
    39241 ctgacaccgc cgggctgtgc caagtacgtg tactgcgcgc gcggcaagac gctcgacata
    39301 gcggtggacg tccgggtcgg ctcgcccacc ttcgggaagt gggacgccgt actgctggac
    39361 accgaggtct tccgctccgt gtacttcccg gtcggcgtgg cccacggctt cgtcgcgctg
    39421 gaggacgaca ccgtggtgtc ctacctgctc tccggggagt acgtcccgga gcacgagctg
    39481 gcactgtcga tcctcgaccc ggacctcgcc ctgcccattc ccggcgacat cgagcccgtc
    39541 ctgtccgagc gcgacctcgc ggcgcccacc ctggagaagg ccgcttcgga cggcctgctg
    39601 cccgactacg ccgagtgcct ggcgatcgac cgcgccctgc gcccggcctg atcggcggcg
    39661 gtacgacgcg cgggggcggc ccaccgggat ccggtgggcc gcccccacgc gtcgctgtcc
    39721 ggccggctca cccgctcaca ggcccagcgc ctcgccgccg ggccgccgag gcgccagcag
    39781 gctgtgcaga caggccacca gggtgcgggc ctgcacgttg aggtagtggc tgtgccgcaa
    39841 cagggtgctg agctggtcca gggtcaccca gcggaagtcc cggtcctcca tggactcggc
    39901 gtcgccctcg gcctcgacga cgaggtaccg gttcagggcg tggtggaaac ggccgccctc
    39961 ctcggacagc aggcaggcga acctggtccg ctccggcggg gccgacagca cgtcgtcgac
    40021 gaagcggggc agggccgcgc ccggcgggac gctctcgggg gtgaactgga cggtgggtga
    40081 gagctcgacc ccgtccacgt agcccggctc cacgctggcc cgcagcagaa tgtggagcac
    40141 cccgtcgatc tgcttgacca gcacggcgat cacgccggtg ccgtgcggct ccagcatggg
    40201 ctgggaccag ccccggacct cgcgcgtgcc cgcggagacg ttcaccccga tcacggagaa
    40261 gaaccgcccg ctggtgtggg agacccgctc cggcgagctg tgccagtcgc gcagctcgac
    40321 cagcggtacc gagcgggtgg tgaggtcgtt ctgggcgcgg tgctcggtga tccagctctg
    40381 gagctcgtcc acgtcgtgca ccccgcccgg ctccccggcg cacgagcggg ccagggcgtc
    40441 ccggaagccg tcgccggtgt ccagcaggac gtcgaggcct ccgccggcca ggggcaggca
    40501 ggacagcgtg gtgcgcgtgt ccatgttgac gatgtcctcg acggccagca gccggtggat
    40561 ctcgccgagg gtcatccagc ggaagtcctc ctcgacggcg atgtcctcgg tgacctcgat
    40621 gacgatgttc cggttgcgct tgcggtagaa ccaggcgccc tgttccgact ggagcacgtc
    40681 ggcgacgacg cggtgccgcg tcctttcctg gaagtacccc agatagggga cggcgcgccc
    40741 tttgtgcagc cgcaggtaat tgctgcgggt ggcctgcacg gtgggggaga gctgcagatg
    40801 gttcctgttc cccggctcga ccttggcctg catgaggaaa tgcagcaccc cgtcgaactc
    40861 cttggccagc aggccgagta cgccgacctc cggctggtgg atgatcggct gctgccagtg
    40921 gggtacggga cccgagggga agcgcacgtc cagcccgtcg atggcgaaga agccgccgct
    40981 ggagtgccgc agcgccccgg tgcgcggatc ccgctcccag ttctcgaggc cgtcgaggtc
    41041 cacgcggtcg acccggaggc ccgaccgttc gcgggcgtcg gcgaaccacg tgacgaacgg
    41101 ggccggttgg cggacccggc tctcctcggc gagggccgac cgtgcgagcc ggtcctggag
    41161 cgtgcggagg gcggtcgggg aagggtgcgg gagggcgatt ctgttcacca gggattcctt
    41221 tgcgccggga ggacagggtc gtgctgcgta ctcggcggtc ttccgcgtcc gcggcgtcga
    41281 ggagagtggc cgtaccggtg tccgcggatg ctcccgtgga ggtggggccg tcgacggcgc
    41341 gcagggccca gtacagtgcg cgctgccagc aacgacctcg aatctccctg aacctgcgcg
    41401 gggggcacgg ccgggagttc gatcgttctt cgagggtgac gcccgatggt tgtcgtcatg
    41461 acgcccccca cgcgcccgta tccgttcgca gagcggaccc ctccccccgg ggtcgagcca
    41521 ggatcgtggc ggcctccaga ggggggggcg gggcgccggt gcgacggggc tccggagccg
    41581 gcaccggccg cgtcctgcca ccgccgcacc ccgacggttg tgcgcaccga aaggaacagg
    41641 cgcatttccg tggtttattg gcgcgaattc gaagcggaat caagacggcg tcatggtgcc
    41701 cgagggcgag cgcatctcgg aagatcctat tccgtttaat cctcgactgt ttcgggtcaa
    41761 cgggtgtgca ggtcgccggt gttgccgggg cgagatgaac ccaggacggt ggcatatggc
    41821 cttgccccgc cttaagggaa gagttaactt agtgcaaagt caggggagaa gtagcttcgt
    41881 gacccttacc tcgaccaagg ggcgctcgaa cctcttgtga ctacgcagtg tcacagcatc
    41941 actgaacggg ggacgtgaga tggacttccg gatgctcggc ccgttggaga ttctcgatgg
    42001 tccgtgcaat gtagtgccca ccgcacccaa gccgcgccag gtgatagccc ttctcctcat
    42061 gaggagaaac accctggtgc agacctctga acttatcgat gaactatggg agagcgatcc
    42121 tcccgcaagt gcgatgacca cactgcaaac gtatatatac aaactccgga agattctcac
    42181 cgcgcggaat tcggaggaaa ttctcttcac ccggcccggg ggatacacgc tggccattcc
    42241 cgaccggtcc gtcgacctcc accgattcga aacggaagcc ggcgagggca agtcgctgtt
    42301 gaagaacgga gacgcggcgg gagcggcgga ggcgctccgc cggtcactcg cgctctggcg
    42361 cggctccgcg ctggtcgacg tcgtgccggg cggtctgctg tcctcgtacg tgacacgact
    42421 cgaggagttc cgggagcgca ccctcgacct gaggatcgag gccgatctcc agctgggtcg
    42481 ccaccaggag ctgatcagcg agctcaagtc gctcgtgctc agccgaccgc tccacgagaa
    42541 cgtgcacgcc tccctgatga tcgccctcca ccgctccggc cggcgccacg aggcgctcga
    42601 ggtctatcag gtgctgcgcc gcagcatgat cgacaacctc ggcctcgaac cgggcaagga
    42661 gctccgggcg ctccaccagg cgctgttgtc cgaggccacg gggggcgtgc tgtacgaacg
    42721 ccaccagcag cccgtcctgg tcgagcccga ccggggtccg gtcgggcatc ccgagccgga
    42781 agagccgccg gtggccgccg cgccccggcc cgccgccgca cccggagtcc ccgcacccgc
    42841 ccagctcccg ccggacatcg ccgacttcac cggcagggag tccatcgtcg accaggcccc
    42901 cgccctcctg gccggggtgg gggagcgaga ccgtcccccc acggccccgg ccgtcgcggt
    42961 catcagcggc atgccgggcg tgggcaagag cgcgctcgcc gtgcacatgt cccacaccgt
    43021 ccggccgttc ttcgaaggcg gacagctcta cgcggatctg cgcggctcca ccggcagggg
    43081 cacggacccc acggaagtgc tccacggatt cctgcgcgcc ctgggcgtcg cggaatccga
    43141 gatccccgcg gacctggagg aacggtccaa gctgttccgc tccaccacgg tcggccggcg
    43201 cctgctgatc ctgctggacg acgtgtcctc gctggccgac gtacgctcgc tgctccccgg
    43261 cgacccggag tgctccgtcg tcatcacgag ccgcaggcgc ctgcacggcc tgggcggcgc
    43321 ctggaacgtc aacctcgacg ccatggacac cgccgagggc cgcgagctgc tcgcccgcat
    43381 catcggatcc gcccgggtca ggcgggagcg caacgccgcc aaccagctga tggagaccgt
    43441 cggcggacat cccctggccg tgcggtgcat cggggggcgc ctcagcggca gtccggggct
    43501 caccctgtcc ggcttagcca cccaactgaa ctgttccgag aagctgctgg acgagctccg
    43561 cctcggggaa ctcgacgtgc gctcccggta cgacttcagc tacgaggggc tcggccgcgt
    43621 cgagcagagc gtcttccggc tgctgagcat cctcccgccc aggcggttca ccgccgattc
    43681 cgtcgtcgag ctcctcggca gcgacagccg cagcgtggag cacctgctcc agcgcttcgt
    43741 cgacagccac ctgatcaaca tcgtccggtg ggaggacggc ggggcccact acgagttccc
    43801 ggaactcacc cgcgtgtacg cccgcgagcg gctgctcgac accctctcgg gcgatggacc
    43861 ggaacacgag ggcatctggc cggaccgccg ccggtgctga
//
