LOCUS       BGC0001857             28117 bp    DNA     linear   PLN 24-FEB-2019
DEFINITION  Aspergillus burnettii strain FRR 5400 burnettramic acid biosynthetic
            gene cluster, complete sequence.
ACCESSION   BGC0001857
VERSION     BGC0001857
KEYWORDS    .
SOURCE      Aspergillus burnettii
  ORGANISM  Aspergillus burnettii
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
REFERENCE   1  (bases 1 to 28117)
  AUTHORS   Li,H., Gilchrist,C.L., Lacey,H.J., Crombie,A., Vuong,D., Pitt,J.I.,
            Lacey,E., Chooi,Y.H. and Piggott,A.M.
  TITLE     Discovery and Heterologous Biosynthesis of the Burnettramic Acids:
            Rare PKS-NRPS-Derived Bolaamphiphilic Pyrrolizidinediones from an
            Australian Fungus, Aspergillus burnettii
  JOURNAL   Org. Lett. (2019) In press
   PUBMED   30735051
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 28117)
  AUTHORS   Gilchrist,C.L.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JAN-2019) School of Molecular Sciences, The University
            of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: SPAdes v. v3.13.0
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            ##antiSMASH-Data-START##
            Version               :: 8.dev-5707d64f
            Run date              :: 2025-08-15 20:25:35
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..28117
                     /db_xref="taxon:2508778"
                     /mol_type="genomic DNA"
                     /organism="Aspergillus burnettii"
                     /strain="FRR 5400"
                     /type_material="culture from holotype of Aspergillus
                     burnettii"
     misc_feature    1..28117
                     /note="burnettramic acid biosynthetic gene cluster"
     region          1..28117
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     subregion       1..28117
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001857"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..28117
                     /SMILES="C([*])C(-O)(C)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..28117
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[15341:27878](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15342..27878
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..28117
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[15341:27878](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      15342..27878
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     mRNA            complement(join(<282..1239,1312..1444,1512..>1893))
                     /product="BuaB"
     CDS             complement(join(282..1239,1312..1444,1512..1893))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /note="glycosyltransferase"
                     /product="BuaB"
                     /protein_id="QBE85641.1"
                     /transl_table=11
                     /translation="MPGQKPVVLFLTNSEFGQSSVVLAVAQELVRQSACEVHVASFSAL
                     KQQVEALNVAFHALPGRSMKEALCDSGLPFLPKHAPGTRGAVESYRKGLQHVVAPWEPA
                     GYEPIYRACLDLLDKLNPDLVAVDPLFGPGQDACNVRQCRYLVLSPASFKDHLVQVQPH
                     LRVLWKYPVISSGLPCPLPLFLIIINFYLIFKLVLHTFLSKRVQTLTKWRNHIGIPGDL
                     TTIYANFNEKVPWLLPSIPQSDFPLKIPTNVTGCGPIIPPFESVAHNPTASWLAQRPTI
                     LFNLGSHMKYKLTDAQQVVTALSMVLHTYPDMQILWKCELSHDDPSSKEPESSDSSAIQ
                     DLIPAELTDRIRVTSWITPSPMSILAHDSTIMYVHHGGSNSFHEALAAGVAQVVCPVWL
                     DTYDVAARVEFLRVGLRGNGKAAPHLEGSELGAAICRTAHRLRSGDMGTRTRELQAHIL
                     AQEEGVSGTGPADVYGVGRRKAAKVILDMITA"
     mRNA            join(<2263..2810,2889..>3414)
                     /product="BuaC"
     CDS             join(2263..2810,2889..3414)
                     /NRPS_PKS="Domain: PKS_ER (23-235). E-value: 6.3e-28.
                     Score: 89.7. Matches aSDomain:
                     nrpspksdomains_QBE85642.1_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /note="enoyl reductase"
                     /product="BuaC"
                     /protein_id="QBE85642.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.7e-13, bitscore:
                     38.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIQHMLPSTQTAIIAGPQGEFQLSHDVPVTPLADDEIIMKTAAV
                     ALNPVDTKLVGDFITPGAIFGFDCAGVIVAVGPKVGNGLAIGDRVCGSARGMNREKPLG
                     GAFAEYVMLPADLTLRIPPAMTFAEAASLGTALVSACMSLFWTMQIPASLQEPAEKPFP
                     VLVYGGSTATGTMLLQVLKICGVRTLTTCSPKNFDLVRSYGADEVFDYNSPTCAQDIRE
                     ATRNNLKYAVDCITEDSTIKICYSAIGRAGGQYIALNPYPEHLATRKVIKPGWILATLI
                     TGEGSAWPEPYHREPDPEIRALAKPAYSAVQKLLDEGRLRSHPIRVKDGGLAAVLDGVE
                     VLRKGEISGQKLVYCFN"
     aSDomain        join(2332..2810,2889..3045)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85642.1_PKS_ER.1"
                     /evalue="6.30E-28"
                     /label="QBE85642.1_PKS_ER.1"
                     /locus_tag="QBE85642.1"
                     /protein_end="235"
                     /protein_start="23"
                     /score="89.7"
                     /tool="antismash"
                     /translation="LSHDVPVTPLADDEIIMKTAAVALNPVDTKLVGDFITPGAIFGFD
                     CAGVIVAVGPKVGNGLAIGDRVCGSARGMNREKPLGGAFAEYVMLPADLTLRIPPAMTF
                     AEAASLGTALVSACMSLFWTMQIPASLQEPAEKPFPVLVYGGSTATGTMLLQVLKICGV
                     RTLTTCSPKNFDLVRSYGADEVFDYNSPTCAQDIREATRNNLKYAVDCI"
     CDS_motif       2455..2493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85642.1_0001"
                     /evalue="1.40E-04"
                     /label="PKSI-ER_m2"
                     /locus_tag="QBE85642.1"
                     /protein_end="77"
                     /protein_start="64"
                     /score="14.6"
                     /tool="antismash"
                     /translation="FGFDCAGVIVAVG"
     mRNA            join(<3894..4103,4171..4233,4332..>5678)
                     /product="BuaD"
     CDS             join(3894..4103,4171..4233,4332..5678)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome p450"
                     /product="BuaD"
                     /protein_id="QBE85643.1"
                     /sec_met_domain="p450 (E-value: 4e-64, bitscore: 206.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVPVLTLLGTLTATGTLVYHFDERLPVVRFRLLTTFLVLSSGQL
                     LLYALWKVFLKPLCFSPFKHLPKPPLDQWPLWRDHEDGQRGGRAQVGIIHCRGILNGER
                     LIVSSPTALAKIASDNYTFIKPMAIKLLAGRVLGMGLVLTERDEHKQQRKLFLPPFAPK
                     HIRDLYPTFWRKSREVTERMGDEIHATGAGNGVFEIGEWAARVALDIITLSTMGKDFGS
                     VRDADAPLAKVYHTVLQPTLGHVVIAVLKNFLPARLVEALPLRSNRHQGDAYDTIRGVC
                     RDLLREKKDQLAGHHLGGKDILSVCLRYEDIAGVDEEEVINQMTTILGAGHETISVGIT
                     WAIYMLCLHRDWQARLREEVRATLPSPDRAQESASSADVERMPLMRAFLEEVLRWYPPI
                     PMTMREPLVDTELDGQYVPRGTRIVVPIKAINREERYWGPDAKRFSPSRWLKNDREFNP
                     SGGVSSKYGYLSFMHGPRSCVASEFARAEMACVVSAWVGRFDLDLSDEHFRDEENMRTS
                     NGNFSGKPLEGLYVRAQVLEGW"
     misc_feature    4272..4277
                     /note="polyC region"
     mRNA            complement(join(<5884..6890,6964..>7072))
                     /product="hypothetical protein"
     CDS             complement(join(5884..6890,6964..7072))
                     /codon_start=1
                     /note="Orf1; Ankyrin repeat domain-containing protein;
                     similar to Aspergillus alliaceus CBS 536.65"
                     /product="hypothetical protein"
                     /protein_id="QBE85644.1"
                     /transl_table=11
                     /translation="MTTPVKGTSPGPDEWHHLEDLNQRRRIQNRLSQRNRRTNLRNQVA
                     QGQKQETAKHSEPKQNRQLFWVPPNSSTAKGKLVTTKGNKLESPRPPDPVTPPGRWPEI
                     WHASLHEKPSGGALHGDLGDDMDSCWINTLIRSPVLPIDDDMLSCTPPIPTFDTTMTLD
                     AAPVPTAMPVRDGGLSEGNTTHIQVPSANGVELGRTGGCKAPQDMHFTVQPQQPMTSIH
                     TDKDRRDHFFGYAALHVAASRGHLAVVQLLTERGIPVDQLSSENETALHLAAEQGHCAV
                     AHYLLERGADPHRGNQYGETALHVAAGHGHCDIVRLLFSYLPDLNIVDRNGHTALLRAV
                     AEGHVDVVRVLLERGMDAGMKVGWPLDQKSI"
     misc_feature    7770..7777
                     /note="polyC region"
     mRNA            complement(join(<7860..8513,8593..8736,8798..>8959))
                     /product="BuaE"
     CDS             complement(join(7860..8513,8593..8736,8798..8959))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /note="proline hydroxylase"
                     /product="BuaE"
                     /protein_id="QBE85645.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 2.2e-19, bitscore:
                     59.2, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVERLDYTDFLNEAPGRQEAFVQHLYAALSRVGFAKITNHPIPE
                     SVILQLFAWTKGFFTLPLEHKRKAAHPPQPNPHRGWSCIGQEKLSVIAQGKAVLDLKES
                     FDMGPGDDELYPNIWTDEGDLPGFRAFMEDFYGRCQSLHLQLLSAIARSMQLPDSYFAP
                     LCSQNSSELRLNHYPAVSRHDLTTGTMRISSHTDFGTITLLFQDSVGGLEVEDQTRPGH
                     YMPVAADDCTDIIVNVGDCLQRWTNDRLRSANHRVTLPRGLTHGMVDDRYSIAYFGKPS
                     RDVSVRTLSALLRANEEAKYREEMTAWQYNQSRLLQTY"
     mRNA            join(<9656..9737,9809..10283,10345..10702,10790..10981,
                     11053..>11184)
                     /product="BuaF"
     CDS             join(9656..9737,9809..10283,10345..10702,10790..10981,
                     11053..11184)
                     /codon_start=1
                     /note="hypothetical protein"
                     /product="BuaF"
                     /protein_id="QBE85646.1"
                     /transl_table=11
                     /translation="MAIASSIGLVAEAIHRHKTPERPIESENDIARYPAEDEQWALDEL
                     QDELCQEEPSDSEDQPKKKIRNPAKLADDFLKRYPPPPSGSAPAGRLPLPVIIPQRRPG
                     VRVRGFVRAYAPDLQACGIDQDTFMDFLVTMTRAGRAPQWMGAANLTAAAAFALPGHAI
                     GCGVGFAIQVVNAIAMEMRGRVQANGFLQKLNQGFFQPRGLYCLVLSFDNTHEEAMTDE
                     SLATAIATTTDPKTGVRKYTDKLRSHSGTTGPSEFPESAPLVFPVLDWLETNANAEQAE
                     KLGRYKKFRKFVADYYDRRAQAEYAARNPTSPLAAPPRRGFTSKLADPNDDTNKSPISL
                     ATGGLVPYNTTWRETRNSEGRRPPRKIADKVLYMIIVNMPSDDDMSRAESIMATEATTE
                     PSVQSDDAEAAKG"
     mRNA            join(<11815..12222,12288..12948,13017..>13459)
                     /product="BuaG"
     CDS             join(11815..12222,12288..12948,13017..13459)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome p450"
                     /product="BuaG"
                     /protein_id="QBE85647.1"
                     /sec_met_domain="p450 (E-value: 1.5e-65, bitscore: 210.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLLILYAFLTAVVARKLSAAVSVYRYRKMHGLLLARPLNQKGDV
                     IGFSLFRGMQKSAREGLSLQRHYENTQQHGPTISAVLLGKSFISTSDPENIKAVLATQF
                     QDFNLGERNDAFAPFLGRGIFTEDGPEWERSRALIRPSLSKAQVAELPIIEQHVQNLLS
                     RIPGDGSTVDLQQLFFNFTLDSATHSLLGQPVGFQLSPAGSEAERFSRAFDDAQAFLQV
                     RAKLGPFRGLVRNKAFEVNCQLVHSAVDRYVSEALGRSARPRSEDGKPGSMRYDLLSEL
                     ASTMTDRTQIRNELLNVLLAARDTTASLLSSVFFMLARHPRVWSRLQQEVVQLEGQRPT
                     YDKLREMRYVRAVLNEALRLFPPVPTNIRCATCHTSLPRGGGVDGLQPVFVANGTIVHY
                     SIWTMHRSTAIYGSDAEEYRPERWLQESDEAPLRPGWGFLPFSGGPRICLGQQKALTEA
                     AYVVIRMLQTFATVQSRDQRPWREHMGLVLSSFHGVQVALRHVEG"
     mRNA            complement(join(<14044..14529,14588..>14641))
                     /product="hypothetical protein"
     CDS             complement(join(14044..14529,14588..14641))
                     /codon_start=1
                     /note="Orf2; similar to Aspergillus alliaceus CBS 536.65
                     jgi.p_Aspalli1_310754"
                     /product="hypothetical protein"
                     /protein_id="QBE85648.1"
                     /transl_table=11
                     /translation="MAAPTEVTLRNLSGTWTLSSSLSDDPSPALELQDVSWLVRNVIAN
                     APVTISITQTVDPTTGVTKIASTQSTLGRTVSDVRYLEWEVEDQQNHPLFGSLSMRSRW
                     AKASDLGEGFLIGNADGEAELIEVLAHGTMAGWTSHQVWAFEEIDGHRYHTRRALVTKG
                     DQQVQVRMVYDWQTEE"
     mRNA            join(<15342..15969,16035..16352,16422..16751,16819..19005,
                     19074..19644,19727..19950,20006..22948,23006..24880,
                     24944..27828,27876..>27878)
                     /product="BuaA"
     CDS             join(15342..15969,16035..16352,16422..16751,16819..19005,
                     19074..19644,19727..19950,20006..22948,23006..24880,
                     24944..27828,27876..27878)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (7-439). E-value:
                     1.3e-164. Score: 540.0. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (545-863). E-value: 2.2e-83.
                     Score: 272.0. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (938-1112). E-value: 5.2e-16.
                     Score: 51.4. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1374-1593). E-value: 5.4e-73.
                     Score: 237.5. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2112-2284). E-value: 1.4e-51.
                     Score: 166.9. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2404-2472). E-value: 6.1e-13.
                     Score: 40.9. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2586-2872). E-value:
                     1.1e-52. Score: 170.9. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3042-3447). E-value:
                     2.8e-85. Score: 278.3. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3573-3637). E-value:
                     1.5e-10. Score: 33.5. Matches aSDomain:
                     nrpspksdomains_QBE85649.1_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3680-3909). E-value: 1.6e-48. Score:
                     157.0. Matches aSDomain: nrpspksdomains_QBE85649.1_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /note="PKS-NRPS"
                     /product="BuaA"
                     /protein_id="QBE85649.1"
                     /sec_met_domain="mod_KS (E-value: 1.6e-140, bitscore:
                     457.9, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 7e-141, bitscore: 459.1,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 7.6e-133, bitscore:
                     432.6, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.3e-76, bitscore:
                     245.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 4.7e-171, bitscore:
                     558.4, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 2e-165, bitscore: 540.0,
                     seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 1.4e-56, bitscore: 181.2,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.3e-84, bitscore: 272.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.6e-45, bitscore:
                     143.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.1e-12, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.8e-46, bitscore:
                     147.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-87, bitscore:
                     282.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 9.8e-33, bitscore:
                     102.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPQNEPIAIVGSGCRFPGEASSPSKLWDLLREPRDVLSKIDRFS
                     ADGFYNKDGHHHGSSNVLHSYQLSEDTRSFDAQFFNIPASEAESMDPQQRFIMEVVYEA
                     LESAAIKIEELSGSPTAVYVGVMCNDYAHITYADLESVPKYAATGTALSILANRISYFF
                     NWTGPSMTIDTACSSSLVALHHAVQTLRGGTSKVAVAAGTNLIFTPTNYIAESNVNMLS
                     PTGRSRMWDANADGYARGEGVAAVVLKTLSQAVADGDRIECVIRETGLNQDGRTPGITM
                     PSSVAQAELIRSTYARAGLDVTRESDRPQFFEAHGTGTKAGDPEEAKAIYKAFFGQEDT
                     MDARDTLYVGSIKTIIGHTEGTAGLAGLLKASLAVQNKTLPPNMHFHTLNPDIEPYYGK
                     LQILTSVKPWPALASGVPRRVSVNSFGFGGANAHAIVESYEPSNGAIKVQSSKETAIPF
                     TFSGYSEKSLMSQLTSFLEYLDSHPEPRLRDSAWTLSRRSAFSTRTTVSGTSIERLQEK
                     LQSKIDSKIKDGKALGIRSSSKNDKILGVFTGQGAQWPRMGLRLLQSSATARRIFDDLE
                     RSLAELPTEDRPSWSLVQELEREAEDSRVMEAEFSQVLCTAVQVMLVDLLHSVGVSFDI
                     VVGHSSGEIGAAYSAGYLSARDAIRIAYYRGKFGKLACGRDGVAGGMLAAGTDMADAKD
                     LCELDDFVGRLQLAASNSSSSVTLSGDAEAVAWAQFVLEDEKKFARLLKVDTAYHSYHM
                     QPCAEPYIEAMKRAGIQALKPQSDCRWFSSVLEGQEVSAAMSASLANSYWRDNLLQPVM
                     FSQALEQAVSNTSDIGLVLEVGPHAALRGPATLTINDKLGRDVPYFGLLSRNADDVESF
                     SDGIGAVWASLARCVIDFTRVDALLADGPEDQPRLCDNVPGYSWDHQRTYWMESRSSAA
                     LRLRPAAHHELLGVRVDSLNREYRWRNFIKPSQLSWTRGHQVQSQLIFPGAGFSVMALE
                     AAKALAPAEKIALVELTDMQVLRAMAFQDENTAVEVICSLSNVIEDPDQANLTANFTCD
                     MCLSKESGFVMAACGAVRLQLGAASSQLLPERTACPVRMNDVNIEHFYSTLWSLGYNYT
                     DMFRSITSLQRTTDAASGIIHTTTEPDYTTSLTLHPATLDVAFQGIFGAMGAPGDGRLW
                     TVLVPTRIKRITINPAVCGGTSGLGVDLPFDASVSVSPIDGVAGDVDIFDSTGVNKAVQ
                     VEGLQVAPLVPVTQSDDREVFSDTIWNFQEPDAARDVPKWTLTDEEWEHARYVERACFY
                     YLKQLHDTITAEERDRCEWHPRKMLDWATEVVGVVSRGEHPIIRQEWMNDTWEMLKGPL
                     DELTAKYEDFESLTHVGKNLIPFVKGEFSLLELVRNGGLLEHIYRNTYAFCEYNNYLAN
                     LVKQLSHRFPRMDIFEIGAGTGSTTEAVLRGIGDHYSSYTYTDLSAGFFPNAQETFKEH
                     DAKMIYKIYDAEKEPGKQGYTERTYDLVIASNVLHATHSLETTLTNARKLLKPGGYLVM
                     LEVTDVNPLRPTFFFGCLPGWWVGENDGRPHHPLVTKERWGELFDRTGFSGLDTSTPSH
                     DVFMAPFSVMLTQAVDRQMALIRQPLQEDNRTTIDHLLILGGTGFTSFMLIEDVKHQLK
                     RYAKHVIVVETLEALEASHFHSRQMLLSLVELDAPVFSPFTPERFAALQMLTEKCRNVL
                     WVVRGASGEQPYANMMNGVARCLVGEQPDMRFQFVDFDMADKVDAGFIVRSLLQLQISD
                     AWHTFIEPYRPVWTLEREVRYIQGQAHIPRYSPSLRRNLQYNSWRRTIRETVDPSSKYV
                     ILTHANGYYDLEEDNSPRPDPMAEDDRMAINVSRSSTVAVEIDGIGHLYILTGECELSG
                     QRVLAFSSHNASRVQVKKDWVVSIGILSSDEPALIQMVTNVCLGTMLLNQTPRNGSLLV
                     YEPTVALARILTALTSAEEPGRVLFTTTNRAKLDSGVAFSFIHPSSPDSSIARWVPAGV
                     AGFVDASGGRKEQNMAARFARHLSSQCRVISMEGFYSNSSHQWGNAGGNSLSALLQHST
                     GLFTQGYKQCKQNQVQELSLDDVIGASTEHKEIRILNWKSQSKALVKLSPVQDEITFKG
                     DRTYLLVGLTGELGRSLCRWMVQRGARYVVLTSRKPDVEPAWLELMQSYGAHIEVMAMD
                     ATDRKSTYNTVRKVQQTLPPVAGVGNGAMVLNDGLFNVISHQDFNQTLRPKVDGTTYLN
                     ELFQSPDLDFFIVFSSLAYVTGNFGQTSYAAANAFMASLVEGRKRRGLPGSVMNLAGIF
                     GLGYITRTDRSILERLGKLGYANISEYDFHQFFAEAVLSGVPGSGRCHEISSALRPIDP
                     DGETNPPAWLDMPRLSYYRHTKHAFTESGDTKSLSVRSQLKEQTTMEDVQRVLTNGLIL
                     TLYKQLGLDPEDDAISPDTSLVELGIDSLVAVDMRVWFTKELDLDMPVLKLLGGATVAA
                     MVEDTMERMSPDLIPNVAQKDVTVAADRPSAPSDGVPAVGRSTAVSTTEHNSEEQESHA
                     METQELDESTTSGGECSSTKESSSSEATPPPSSVMSEDLAKVEETASIDGPKYVRKVKM
                     GYGSLQFFFLVKHLDDPTVLNMQFRLPLQGSIKIPDLKYAVKMLGQRHEALRTAFFVDA
                     ENDDEPTQGVLETSPLQLETMQVTDSKEARRVCEDVQKYVFNIESGETIRILLLSITPS
                     SHWLVLSFHHISIDGFSFNILLDEINALYQGQHLPPVKTQFTDVMCKQRQDLQAGFRRS
                     ELAYWQQVLGKIPDPIPLFPVAKLSSRLPVTRYHFEEAPMASIDAATAEQIRKQCRALK
                     ATRFHFFMTVLRIFLFAFLDTDELCIGFADASRADSGVSRTVGYLVNMLSLKFQRKPSQ
                     TFAQKVEEARKQSYAALANSTVPFNALLEKLEPPRSAAYTPVFQVFMDYLQHKFTAPKG
                     LGVVEEQVYAHLTHNFFDLAVDINDVSASEILVRFRMQQYLYSASSVSLLLKSYVQLVK
                     MCAYMEPNKAIGEPVPYDAQDIERAISLGQGPVVSSQWPSTPIERILDVAQARPEAPAL
                     VDGEGARLSYMEMIDRAHSIAGCLLTAGVAEGSTVGVYQEPTADSICSLLAIWIIGAVY
                     LPLDRRVPCSRLSSIVQDCQPSAILCHERTLSDTPYLEATKQTAIITVPVNVAGIEAAP
                     VPLNTGNGDQTSIILYTSGSTGVPKGLPIRHVSLLNQIEAMTTTFGVGAEMVLQQSAPS
                     FDVSMQQILMALCNGGALYVVPNETRLDPVTITRLIASEKITWVHATPSEFTQWLRHGS
                     AHLRAAKDWKFAFSSGEALSSDLVKGFEALRRPDVKLINVYGPAEAGVITGTEIDTTHV
                     SAEPRSPISLGSPLANIAVYVVDRNLRPVPVGVSGEIVVAGAGNISGYLNRFELTAKLF
                     LPDTITPRGYYPGQLATLYRSGDIGRYSPDGQLYYEGRIAGDTQVKLNGIRIDLKDVES
                     AILETSGGEIVNAIVTDRRSPDFLVAHVELKADFPEAERKNFLTYIQQCLPLPKYMCPA
                     MFIPLDHVPLNSHGKLDRRAIAARPLPTVDGDDQQGDADLSETELALRELWTGCLPEDV
                     VKLTSISATTDFFHLGGNSYLLVRLQRLIRDRFNVSVPVMALYDASTLMAMALKIRNSQ
                     SLAVIDWDTETSVAQSLGASPCAEQPTAPRKTTDLTVVLTGATGYLGSRIMKALIASEQ
                     VSQIHCVAVRGHSAGVPRELAHSSDKLILHGGHLEDPLLGMSEEEFTFVARETDLVIHS
                     GANRSFWDHYERLRGPNVLSTKTLVDLALQNQAPLHFISSGGVHLLCSGEDYAAESLAS
                     YLPPTDGSNGYIASKWASEVYLEKAAQKTSLPVYVHRLTPAPDVTPDAPMELLEEMSAL
                     AVKLQALPAPSGWTGTFDLTPAEALATGIAAAAVGAQAPMLESHQSARFIHHPSQVKMT
                     MDHVAKYLDMLPSAEGFERLPPLQWAGRAKREGLTWHFSSTDFITMGG"
     aSDomain        join(15363..15969,16035..16352,16422..16751,16819..16859)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.30E-164"
                     /label="QBE85649.1_PKS_KS.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="439"
                     /protein_start="7"
                     /score="540.0"
                     /tool="antismash"
                     /translation="IAIVGSGCRFPGEASSPSKLWDLLREPRDVLSKIDRFSADGFYNK
                     DGHHHGSSNVLHSYQLSEDTRSFDAQFFNIPASEAESMDPQQRFIMEVVYEALESAAIK
                     IEELSGSPTAVYVGVMCNDYAHITYADLESVPKYAATGTALSILANRISYFFNWTGPSM
                     TIDTACSSSLVALHHAVQTLRGGTSKVAVAAGTNLIFTPTNYIAESNVNMLSPTGRSRM
                     WDANADGYARGEGVAAVVLKTLSQAVADGDRIECVIRETGLNQDGRTPGITMPSSVAQA
                     ELIRSTYARAGLDVTRESDRPQFFEAHGTGTKAGDPEEAKAIYKAFFGQEDTMDARDTL
                     YVGSIKTIIGHTEGTAGLAGLLKASLAVQNKTLPPNMHFHTLNPDIEPYYGKLQILTSV
                     KPWPALASGVPRRVSVNSFGFGGANAHAIVESY"
     aSModule        15363..23220
                     /complete
                     /domains="nrpspksdomains_QBE85649.1_PKS_KS.1"
                     /domains="nrpspksdomains_QBE85649.1_PKS_AT.1"
                     /domains="nrpspksdomains_QBE85649.1_PKS_DH.1"
                     /domains="nrpspksdomains_QBE85649.1_cMT.1"
                     /domains="nrpspksdomains_QBE85649.1_PKS_KR.1"
                     /domains="nrpspksdomains_QBE85649.1_PKS_PP.1"
                     /iterative
                     /locus_tags="QBE85649.1"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       15840..15887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0001"
                     /evalue="5.10E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="QBE85649.1"
                     /protein_end="182"
                     /protein_start="166"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     CDS_motif       16094..16132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0002"
                     /evalue="1.00E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="QBE85649.1"
                     /protein_end="242"
                     /protein_start="229"
                     /score="12.2"
                     /tool="antismash"
                     /translation="WDANADGYARGEG"
     CDS_motif       16112..16189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0003"
                     /evalue="2.30E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="QBE85649.1"
                     /protein_end="261"
                     /protein_start="235"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="GYARGEGVAAVVLKTLSQAVADGDRI"
     CDS_motif       join(16340..16352,16422..16453)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0004"
                     /evalue="4.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="QBE85649.1"
                     /protein_end="326"
                     /protein_start="311"
                     /score="9.9"
                     /tool="antismash"
                     /translation="FEAHGTGTKAGDPEE"
     CDS_motif       17178..17228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0005"
                     /evalue="3.40E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="QBE85649.1"
                     /protein_end="562"
                     /protein_start="545"
                     /score="13.3"
                     /tool="antismash"
                     /translation="VFTGQGAQWPRMGLRLL"
     aSDomain        17178..18131
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_PKS_AT.1"
                     /evalue="2.20E-83"
                     /label="QBE85649.1_PKS_AT.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="863"
                     /protein_start="545"
                     /score="272.0"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWPRMGLRLLQSSATARRIFDDLERSLAELPTEDRPSW
                     SLVQELEREAEDSRVMEAEFSQVLCTAVQVMLVDLLHSVGVSFDIVVGHSSGEIGAAYS
                     AGYLSARDAIRIAYYRGKFGKLACGRDGVAGGMLAAGTDMADAKDLCELDDFVGRLQLA
                     ASNSSSSVTLSGDAEAVAWAQFVLEDEKKFARLLKVDTAYHSYHMQPCAEPYIEAMKRA
                     GIQALKPQSDCRWFSSVLEGQEVSAAMSASLANSYWRDNLLQPVMFSQALEQAVSNTSD
                     IGLVLEVGPHAALRGPATLTINDKLGRDVPYFGLLSR"
     CDS_motif       17430..17537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0006"
                     /evalue="9.80E-10"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="QBE85649.1"
                     /protein_end="665"
                     /protein_start="629"
                     /score="30.9"
                     /tool="antismash"
                     /translation="GVSFDIVVGHSSGEIGAAYSAGYLSARDAIRIAYYR"
     aSDomain        18357..18878
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_PKS_DH.1"
                     /evalue="5.20E-16"
                     /label="QBE85649.1_PKS_DH.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="1112"
                     /protein_start="938"
                     /score="51.4"
                     /tool="antismash"
                     /translation="HELLGVRVDSLNREYRWRNFIKPSQLSWTRGHQVQSQLIFPGAGF
                     SVMALEAAKALAPAEKIALVELTDMQVLRAMAFQDENTAVEVICSLSNVIEDPDQANLT
                     ANFTCDMCLSKESGFVMAACGAVRLQLGAASSQLLPERTACPVRMNDVNIEHFYSTLWS
                     LGYNYTDMFRS"
     CDS_motif       18438..18515
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0007"
                     /evalue="2.80E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="QBE85649.1"
                     /protein_end="991"
                     /protein_start="965"
                     /score="29.4"
                     /tool="antismash"
                     /translation="WTRGHQVQSQLIFPGAGFSVMALEAA"
     CDS_motif       19256..19291
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0008"
                     /evalue="2.40E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="QBE85649.1"
                     /protein_end="1227"
                     /protein_start="1215"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="DSTGVNKAVQVE"
     aSDomain        join(19815..19950,20006..20526)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="5.40E-73"
                     /label="QBE85649.1_cMT.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="1593"
                     /protein_start="1374"
                     /score="237.5"
                     /tool="antismash"
                     /translation="ELVRNGGLLEHIYRNTYAFCEYNNYLANLVKQLSHRFPRMDIFEI
                     GAGTGSTTEAVLRGIGDHYSSYTYTDLSAGFFPNAQETFKEHDAKMIYKIYDAEKEPGK
                     QGYTERTYDLVIASNVLHATHSLETTLTNARKLLKPGGYLVMLEVTDVNPLRPTFFFGC
                     LPGWWVGENDGRPHHPLVTKERWGELFDRTGFSGLDTSTPSHDVFMAPFSVMLTQA"
     CDS_motif       22084..22179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0009"
                     /evalue="8.80E-17"
                     /label="PKSI-KR_m1"
                     /locus_tag="QBE85649.1"
                     /protein_end="2144"
                     /protein_start="2112"
                     /score="53.6"
                     /tool="antismash"
                     /translation="TYLLVGLTGELGRSLCRWMVQRGARYVVLTSR"
     aSDomain        22084..22599
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_PKS_KR.1"
                     /evalue="1.40E-51"
                     /label="QBE85649.1_PKS_KR.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="2284"
                     /protein_start="2112"
                     /score="166.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYLLVGLTGELGRSLCRWMVQRGARYVVLTSRKPDVEPAWLELMQ
                     SYGAHIEVMAMDATDRKSTYNTVRKVQQTLPPVAGVGNGAMVLNDGLFNVISHQDFNQT
                     LRPKVDGTTYLNELFQSPDLDFFIVFSSLAYVTGNFGQTSYAAANAFMASLVEGRKRRG
                     LPGSVMNLA"
     CDS_motif       22453..22560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0010"
                     /evalue="1.70E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="QBE85649.1"
                     /protein_end="2271"
                     /protein_start="2235"
                     /score="52.7"
                     /tool="antismash"
                     /translation="LDFFIVFSSLAYVTGNFGQTSYAAANAFMASLVEGR"
     aSDomain        23017..23220
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_PKS_PP.1"
                     /evalue="6.10E-13"
                     /label="QBE85649.1_PKS_PP.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="2472"
                     /protein_start="2404"
                     /score="40.9"
                     /tool="antismash"
                     /translation="LTLYKQLGLDPEDDAISPDTSLVELGIDSLVAVDMRVWFTKELDL
                     DMPVLKLLGGATVAAMVEDTMER"
     aSDomain        23563..24420
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.10E-52"
                     /label="QBE85649.1_Condensation_LCL.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="2872"
                     /protein_start="2586"
                     /score="170.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHISIDG"
                     /tool="antismash"
                     /translation="LQFFFLVKHLDDPTVLNMQFRLPLQGSIKIPDLKYAVKMLGQRHE
                     ALRTAFFVDAENDDEPTQGVLETSPLQLETMQVTDSKEARRVCEDVQKYVFNIESGETI
                     RILLLSITPSSHWLVLSFHHISIDGFSFNILLDEINALYQGQHLPPVKTQFTDVMCKQR
                     QDLQAGFRRSELAYWQQVLGKIPDPIPLFPVAKLSSRLPVTRYHFEEAPMASIDAATAE
                     QIRKQCRALKATRFHFFMTVLRIFLFAFLDTDELCIGFADASRADSGVSRTVGYLVNML
                     SLKFQ"
     aSModule        23563..27594
                     /complete
                     /domains="nrpspksdomains_QBE85649.1_Condensation_LCL.1"
                     /domains="nrpspksdomains_QBE85649.1_AMP-binding.1"
                     /domains="nrpspksdomains_QBE85649.1_PP-binding.1"
                     /domains="nrpspksdomains_QBE85649.1_TD.1"
                     /final_module
                     /locus_tags="QBE85649.1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23608..23715
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0011"
                     /evalue="5.80E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="QBE85649.1"
                     /protein_end="2637"
                     /protein_start="2601"
                     /score="21.9"
                     /tool="antismash"
                     /translation="LNMQFRLPLQGSIKIPDLKYAVKMLGQRHEALRTAF"
     CDS_motif       23926..23991
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0012"
                     /evalue="5.40E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="QBE85649.1"
                     /protein_end="2729"
                     /protein_start="2707"
                     /score="22.2"
                     /tool="antismash"
                     /translation="FHHISIDGFSFNILLDEINALY"
     CDS_motif       24463..24582
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0013"
                     /evalue="6.40E-11"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="QBE85649.1"
                     /protein_end="2926"
                     /protein_start="2886"
                     /score="34.6"
                     /tool="antismash"
                     /translation="RKQSYAALANSTVPFNALLEKLEPPRSAAYTPVFQVFMDY"
     aSDomain        24994..26208
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_AMP-binding.1"
                     /evalue="2.80E-85"
                     /label="QBE85649.1_AMP-binding.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="3447"
                     /protein_start="3042"
                     /score="278.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DVAQARPEAPALVDGEGARLSYMEMIDRAHSIAGCLLTAGVAEGS
                     TVGVYQEPTADSICSLLAIWIIGAVYLPLDRRVPCSRLSSIVQDCQPSAILCHERTLSD
                     TPYLEATKQTAIITVPVNVAGIEAAPVPLNTGNGDQTSIILYTSGSTGVPKGLPIRHVS
                     LLNQIEAMTTTFGVGAEMVLQQSAPSFDVSMQQILMALCNGGALYVVPNETRLDPVTIT
                     RLIASEKITWVHATPSEFTQWLRHGSAHLRAAKDWKFAFSSGEALSSDLVKGFEALRRP
                     DVKLINVYGPAEAGVITGTEIDTTHVSAEPRSPISLGSPLANIAVYVVDRNLRPVPVGV
                     SGEIVVAGAGNISGYLNRFELTAKLFLPDTITPRGYYPGQLATLYRSGDIGRYSPDGQL
                     YYEGRI"
     CDS_motif       25420..25476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0014"
                     /evalue="6.90E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="QBE85649.1"
                     /protein_end="3203"
                     /protein_start="3184"
                     /score="18.7"
                     /tool="antismash"
                     /translation="IILYTSGSTGVPKGLPIRH"
     CDS_motif       26002..26091
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0015"
                     /evalue="8.50E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="QBE85649.1"
                     /protein_end="3408"
                     /protein_start="3378"
                     /score="27.7"
                     /tool="antismash"
                     /translation="PVGVSGEIVVAGAGNISGYLNRFELTAKLF"
     CDS_motif       26215..26265
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0016"
                     /evalue="3.50E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="QBE85649.1"
                     /protein_end="3466"
                     /protein_start="3449"
                     /score="13.4"
                     /tool="antismash"
                     /translation="DTQVKLNGIRIDLKDVE"
     aSDomain        26587..26778
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_PP-binding.1"
                     /evalue="1.50E-10"
                     /label="QBE85649.1_PP-binding.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="3637"
                     /protein_start="3573"
                     /score="33.5"
                     /tool="antismash"
                     /translation="RELWTGCLPEDVVKLTSISATTDFFHLGGNSYLLVRLQRLIRDRF
                     NVSVPVMALYDASTLMAMA"
     CDS_motif       26905..26964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBE85649.1_0017"
                     /evalue="1.20E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="QBE85649.1"
                     /protein_end="3699"
                     /protein_start="3679"
                     /score="1.9"
                     /tool="antismash"
                     /translation="TVVLTGATGYLGSRIMKALI"
     aSDomain        26908..27594
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBE85649.1_TD.1"
                     /evalue="1.60E-48"
                     /label="QBE85649.1_TD.1"
                     /locus_tag="QBE85649.1"
                     /protein_end="3909"
                     /protein_start="3680"
                     /score="157.0"
                     /tool="antismash"
                     /translation="VVLTGATGYLGSRIMKALIASEQVSQIHCVAVRGHSAGVPRELAH
                     SSDKLILHGGHLEDPLLGMSEEEFTFVARETDLVIHSGANRSFWDHYERLRGPNVLSTK
                     TLVDLALQNQAPLHFISSGGVHLLCSGEDYAAESLASYLPPTDGSNGYIASKWASEVYL
                     EKAAQKTSLPVYVHRLTPAPDVTPDAPMELLEEMSALAVKLQALPAPSGWTGTFDLTPA
                     EALATGI"
ORIGIN
        1 atttagggta aggaagtctc cgatgaagcc atagggttaa ggccccacac ataggcatac
       61 tggacataga agattgactc tccaatgcct ttagcccagg ttcgccgtgt tcccggtgga
      121 ctttcgcttc gctaggaagc cgtcgaggtt acaatatttc ggttaaagag tcactgcata
      181 tctattctga gtataggaaa tgggctaatg tcaaccaacg ctcccggatg acacttcaca
      241 cgtcggtgct gctaccaaaa ataaggaagt atactaatat gtcacgccgt gatcatgtcc
      301 aatatgacct tggcggcttt gcgacgccca acaccataca cgtccgccgg gcccgtccca
      361 ctaacgccct cctcctgcgc cagaatgtgg gcctgcaact ctcgggtccg agtacccata
      421 tctccgcttc tgagtctatg cgccgtccga cagatggctg cgcctaactc agagccctcg
      481 agatgcggcg ccgccttgcc attccccctc aagccaacac gaaggaactc gacccgggca
      541 gcgacatcgt acgtatccag ccacaccgga cacaccactt gcgcgacgcc ggcagctagc
      601 gcctcatgga acgagttcga tcctccatgg tggacataca tgatagtgct gtcatgagcg
      661 aggatagaca tgggagacgg cgtgatccat gacgtgacac gaatgcgatc ggtcagttca
      721 gccggaatca agtcctggat ggccgaagaa tcagaagatt ctggttcctt gctgctgggg
      781 tcatcatgtg atagttcaca tttccacaga atctgcatat cggggtatgt gtgtagcacc
      841 attgagaggg cagtcacaac ctgctgcgcg tcagtcagtt tgtatttcat gtgcgagcct
      901 aggttaaaga ggatcgttgg acgctgggcc agccaggatg cggtgggatt gtgggccact
      961 gattcgaatg gcggaattat gggtccacag cctgtgacgt tggtgggaat cttgaggggg
     1021 aagtcgcttt gtgggattga cggcagtagc caagggactt tttcattgaa attggcgtat
     1081 attgtggtta gatcgcctgg gatgccgatg tggttgcgcc acttggtcaa tgtttggacc
     1141 ctcttggaga gaaaagtatg caagaccagc ttgaatatca ggtagaagtt gatgatgatg
     1201 aggaataggg gcagagggca gggcagccct gaggatattc tgtcgccgat tatcaggtat
     1261 cagcgttcgg atgctatgaa agagaagagg gaagaggtag tgggagcgca cactgggtac
     1321 ttccatagaa ccctgagatg gggttggact tggaccagat ggtctttgaa cgaggctggg
     1381 ctcaggacca aataccgaca ctgtcggaca ttgcaggcgt cttggccagg accaaacagg
     1441 ggatctatgt acgagaacca agttagcagc tgctatggag atatggtgac agccaacgtt
     1501 ggatgacgta cccacagcaa ccaagtctgg gttgagctta tcaaggaggt ccaggcaggc
     1561 ccggtagatg ggctcgtagc cagccggttc ccacggggca accacatgct gcaggccctt
     1621 gcgataggat tcaacggcac cacgagtgcc gggcgcgtgc ttagggagga agggaaggcc
     1681 gctgtcgcag agcgcttcct tcattgaccg tccggggagg gcatggaagg cgacattgag
     1741 agcttcgacc tgttgtttga gagctgagaa cgaggcaaca tgcacctcac aggcagactg
     1801 acggactagc tcctgcgcaa cagctagaac caccgatgac tgcccaaatt cactgttggt
     1861 gaggaagaga acaactggtt tttggcccgg catggtaggt gaggagggga gatgctgtat
     1921 ctgcacctac agcgtgatgt ctcctgatga tcgaatccga ctgcctggca aacgtcagtt
     1981 actagtatat cgcggccccg taagaatgtg gagtctggaa gattatcgat gaaccaacat
     2041 tcctgatccg gttcgctgaa ttccgcctcc aggcttagtt gtcagattcc atttcctatt
     2101 taggatagca ctccgtttta gcaccatgag agtccctgtg ttggcaacaa tgttggaggc
     2161 tctttaactg cagatgcgtg ctaatccccg gggacgttta ttctttctat acagccatcg
     2221 ttgttacagg agatacgacg gatacttcta gtcgaaacaa acatggggat ccaacatatg
     2281 cttccgtcca cccagaccgc aatcattgct ggtccccaag gcgagttcca gctctctcat
     2341 gacgtgcctg ttaccccctt ggccgacgat gagatcatca tgaagaccgc ggctgtcgct
     2401 ctcaaccccg tcgacaccaa gctagtgggc gatttcatca cgccgggcgc catcttcggt
     2461 ttcgactgcg caggtgtgat cgtagccgtt ggacctaagg ttggcaatgg cctggcgatt
     2521 ggggaccgcg tctgcgggag cgctcgcggc atgaaccgag agaaaccgct agggggagcc
     2581 tttgcagagt acgtgatgct gccggccgat ctcacgctac gcatcccacc tgccatgacg
     2641 ttcgcagagg ctgcgtcgct cgggaccgcg ctggtgtcgg cgtgcatgtc gctgttctgg
     2701 acgatgcaaa tccccgcgtc cctccaggaa ccggcagaga aaccgtttcc tgtcctcgtc
     2761 tatggaggca gtactgcgac cgggaccatg ctgctccagg tgctgaagat gtatgtctga
     2821 ccaaccccaa acccacctcc tctccagagt gacattgcgc aaggccatcc cagttgacac
     2881 agaagtagtt gcggtgtccg aacacttacc acctgctctc ccaagaactt tgatctggtg
     2941 cgttcgtatg gcgcagatga agtgttcgat tacaactcgc ccacctgcgc ccaggacatc
     3001 cgcgaggcga cgcgcaacaa cctaaagtac gcagtagact gcatcaccga ggactcgacc
     3061 atcaagatct gctacagtgc gattggccgt gcgggagggc aatacatcgc gctcaatccc
     3121 taccccgagc atttggccac tcgcaaggtc atcaagccgg gttggatcct ggccacgctc
     3181 atcaccggcg agggttctgc ctggccggag ccctaccatc gcgagccgga ccctgagatc
     3241 cgggccctgg ctaagcccgc ctactctgcg gtgcagaagt tgctagacga gggtcgcctt
     3301 cggtcgcacc ccatccgggt gaaggacggg ggcttggcgg cggtgctgga cggagtggag
     3361 gtgttgcgca agggagagat cagcggtcag aaattagtgt attgctttaa ttaggtagtc
     3421 tagcgtggat gagaagggct tgttttctga tctgcagagg caaatattca gaaacggtag
     3481 cgaagcaaaa gttactaaaa agcaactatg ccaaaacggg tcaatgtcag atctccagtc
     3541 agcccgatag tccggactca ataccgacaa ggtgggccac ctgcaggttg tcagactgct
     3601 ggattttggc tgtgcttatt cctctttcag cttatccttc tgtaagcttt ctaaatatcc
     3661 cctagaaagg tagtcgtccc gagaggctga tgatgttcct aatgtggaaa tgtagggcta
     3721 gccacgagtt gcccgttgag gttgcagatg agaaaggaat cacagctcgt tgcacgcaca
     3781 aatacacagc tagattaaac tatactgaaa tggacctatt tctgcccttt ctattttcat
     3841 tatcattttt taatttgttt tctttttact ttctggtttg agtaccttcg agaatgttag
     3901 tcccagtgct aacgctgctg ggcacactga ctgccacagg cactctagtg taccatttcg
     3961 atgaacgact ccccgtggtg cgattccgtc ttctgaccac cttccttgtc ctctcttctg
     4021 gccagcttct actctatgct ttgtggaagg tgtttctgaa gccactctgc ttctctccgt
     4081 tcaagcacct gcccaagcct ccggtgagcg ttttctcttc ctactgatac ccggaagatt
     4141 ctctgatcat agatgtctac agggaggtag ctggatcaat ggccactttg gagagatcat
     4201 gaagatgggc aacggggagg ccgagctcaa gtggtaagtg agattctccc gttctcagaa
     4261 cacccacccc ccccccccgg gatgaagggt tgaaaagtaa aaacaacagg atgaaagatg
     4321 tccccaataa gggtatcatc cattgtcgag gcatcctgaa tggcgagcgt ctcatagtgt
     4381 cctcgcccac agcgcttgcc aagatcgcca gtgacaacta caccttcatc aagcccatgg
     4441 cgatcaagct gctagccggc cgcgtgctgg gcatgggact tgtcctgacc gagcgcgacg
     4501 agcacaagca gcagcgcaag ctcttcctgc cgccgttcgc cccgaagcac attcgggacc
     4561 tctacccaac cttctggcgg aagagccgcg aggttacaga acggatgggc gacgagatcc
     4621 acgccacggg ggccgggaat ggcgttttcg agattggtga atgggcagcg cgcgtggcgc
     4681 tggatatcat caccctgtcg accatgggca aggattttgg ctcggttcgc gatgccgacg
     4741 cgccgctggc taaggtgtac cacactgtgt tgcaaccgac tttgggccat gtggtgatcg
     4801 ccgtgctgaa gaatttcctg cccgcacgac tggtggaggc cctaccgctg cggtctaatc
     4861 ggcatcaggg agacgcctac gacacgatac gcggggtgtg tcgggaccta ctgagggaga
     4921 agaaggacca gctggcaggc caccatctag gcggcaagga tatcctgagc gtgtgcctgc
     4981 gatacgagga cattgccggc gtcgacgagg aggaggtcat caaccaaatg acgaccatcc
     5041 tgggagcagg ccatgagacc atctcggtgg gcatcacctg ggctatctat atgctctgct
     5101 tgcaccggga ctggcaggcc cggctgcgcg aggaggtgcg tgccacactg ccctcccccg
     5161 accgcgcgca ggagtctgcg tccagcgccg atgtcgagcg tatgccgctg atgcgcgcct
     5221 ttctggagga ggtgctgcgg tggtatccgc ccatccccat gaccatgcgt gagccactgg
     5281 tcgatacgga gctggatggc cagtacgtgc cccggggcac gcgcatcgtg gtccccatca
     5341 aggctatcaa ccgtgaggag aggtattggg ggcccgatgc gaaacggttt agcccgtcgc
     5401 ggtggctgaa gaacgaccgt gagtttaacc ccagtggtgg ggtatcgagc aagtacggct
     5461 atctgtcttt catgcacggc cctcgcagct gcgtggcgtc cgaatttgcc cgcgctgaga
     5521 tggcatgcgt ggtatcggcg tgggtaggac gctttgactt ggacctttcg gacgagcact
     5581 ttcgggacga ggagaatatg aggacgtcga acggcaattt ttcagggaag cccctagaag
     5641 ggctgtatgt gcgggcacag gtgctggagg gctggtagtc gtaggagagt aggcgttgat
     5701 cacgagatgg ctggcaattt tagaatacaa tcagatatca cagcttgacc aaatgtaatc
     5761 aataacaccg ggacccaaac cctatgtaca taaaaagtac tgctctgtat cgaacaagaa
     5821 agtaggaaac atacaggaat tccactgttc ttcatgtccc tccacggtct ctgtctagat
     5881 caatcaaatg cttttttgat ccaacggcca ccctaccttc attccagcgt ccatgccacg
     5941 ctccagcaac acccgcacga catcgacatg cccctccgct actgcccgaa ggagcgccgt
     6001 gtggccattg cgatccacaa tattcaaatc cggtagatag ctgaaaagca ggcggacaat
     6061 atcgcaatgt ccatgacccg cggcgacgtg cagggccgtt tcgccatact ggttgccacg
     6121 gtgtgggtca gccccacgct ccagcaggta atgtgcgaca gcacaatggc cctgctccgc
     6181 tgccagatgc agggctgtct cgttctcact gctcaactga tcgaccggga ttccccgctc
     6241 cgtgagcagc tgcacaacag caagatggcc ccgactggca gccacgtgga gtgctgcata
     6301 tccgaagaag tgatccctgc ggtccttgtc cgtgtgaata ctggtcattg gctgttgtgg
     6361 ttgcactgtg aagtgcatat cttgtggtgc cttgcagcct cccgtgcgac ctaactcgac
     6421 tccgttcgcc gagggaactt gaatatgcgt tgtgttcccc tcggatagcc caccatccct
     6481 caccggcatt gccgtcggta ctggtgcggc atccaacgtc atggtcgtgt cgaatgtagg
     6541 tatcgggggc gtgcagctca gcatatcgtc gtcaataggc aggacgggcg agcggataag
     6601 cgtgttgatc cagcaggaat ccatgtcatc tcccaggtca ccgtgtaatg caccacccga
     6661 cggtttctcg tgcagcgaag cgtgccagat ctccggccaa cgaccagggg gcgtcactgg
     6721 atctgggggg cgaggcgact cgagcttgtt accttttgtc gtcaccaatt tcccctttgc
     6781 ggtagaggaa ttaggtggca cccagaagag ctgtcggttc tgcttgggct cggagtgctt
     6841 ggccgtttct tgcttttggc cctgggctac ctggttgcgc aggttggttc cttaaactgc
     6901 ggttcagtcg gtgatgcggc taatctaacg gcaactatct agatagttag atggtacact
     6961 tacgccgatt ccgctgcgat aggcggttct ggatccgtcg cctctgattc aaatcctcca
     7021 gatggtgcca ctcatcgggg ccgggagagg ttcccttgac gggagtggtc atggccgggg
     7081 caccgattaa gctacgcagg gggggtttac gaactcgtcg ggcgtgactt gctataagta
     7141 tggcttggca atattaagtc tcagagtaga aaggacagtg tggcaatctt gataatggct
     7201 gatgactagg ttcggagcgt tgggggttcc aaatgaatcc agggcgagag gaattataat
     7261 tgcatcagtc gccctgacca tggacacgag aaatactacc aataaatgac taagtatcat
     7321 tctaacaggg ggataatgca gctaacaata gcatctagtg tctagactac ataggcggat
     7381 ttaacctgca tgattgaacg tcacagtaac aagggtggcc ttacaaagta tgaatataga
     7441 gcgtgtgagg gtgaatcatg gtatcactca tgtaggaatt aggctgaaat catctcgcgt
     7501 ggtagcaggg ggatgaagag tttctggtct gacgagagaa gtatagcaag acaagatggt
     7561 tagttcgaaa gctcactgga ccaatgaaga tgtgcttatg gtgggctgca gagtgaatac
     7621 tactacatct tgactccaat ttctctcgaa tggcccccat aagtcaagac aaagtggggc
     7681 tagacttaac cacgaagcta acgtgttcga tagatccaac cacaaggtac attgggatgt
     7741 gttcgttggc cccccccccc cccccccccn nnnnnnnccc cttggcccgc ttaccattct
     7801 atgttgcttt ctcatcccta gtctccaccc tctccaatcg tcagccatcc taaattgccc
     7861 tagtatgtct gcaagagacg ggattggttg tattgccagg ctgtcatctc ctctcggtac
     7921 ttggcctcct catttgcgcg cagtagggct gacagagtgc gcactgaaac atcgcgactc
     7981 ggtttgccaa agtaggcaat ggagtatcta tcatccacca tgccgtgggt cagtcctcgt
     8041 ggtagggtta ctcgatgatt ggccgagcgc agccggtcgt tggtccagcg ctgcagacag
     8101 tctcccacgt ttacgattat atcggtgcag tcgtccgccg cgacgggcat gtaatggccc
     8161 ggtcgcgtct ggtcctcgac ctccagaccc ccaacggagt cctggaagag caaagtgatg
     8221 gtcccgaaat cagtatggct cgaaatgcgc atagttccgg tcgtgagatc gtgccgcgac
     8281 acagccggat agtggtttaa gcgcaactcg ctgctattct ggctgcataa cggagcaaag
     8341 tacgaatccg gtaactgcat cgaccgcgca atagctgaca gcagctgcag gtgcaaggat
     8401 tggcatcgtc cgtagaagtc ctccatgaag gcacgaaatc ccgggagatc gccctcgtcg
     8461 gtccaaatgt tgggatacag ttcatcatca cctggcccca tgtcgaaaga ctcctgtatc
     8521 gcccccatcg gtgtcagagc tgatctgatt aaccccagcc tcctacgaac gcacaaacac
     8581 gagtcaatat accttgagat ccaaaacagc ttttccctgg gcgatgaccg ataacttctc
     8641 ttgaccaatg cagctccacc cacggtgggg gttaggctgt ggggggtgag cggcctttcg
     8701 tttgtgctcg agcggcagcg tgaaaaaacc cttggtctgt ttggtgagcc actgaataaa
     8761 tacaaatcac tagctgggag tttgcgtatg tacctaccca tgcgaataat tgcaagataa
     8821 cggactctgg gatgggatgg ttagttattt tcgcgaaccc tacacgcgag agtgcagcgt
     8881 agagatgctg gacgaaggcc tcctgtcggc caggcgcttc attgagaaaa tctgtgtagt
     8941 cgagtcgttc aacctccatg gcgttgaggg atggatggag ttacatcgat gggaaactag
     9001 tgaagccaca ggatgggagt tatacaacat catcttgatc ggacataatt ggacaccatc
     9061 agacatgatc ttccaccgag cagtattcca aaagaggcat gctgacgggc attagcgtgt
     9121 tcggatggtt ggtgggacgc tgggcgcttg tcaatccctt acgggctagg cgatcagcct
     9181 ggtgcttatg ttttctttgt gcaaagtacc gttctgggca aactggggct gtcagattct
     9241 ccatcaatag tgctttagtt agtgtgcagc accccttgcc acaaccgtcc aatccagggc
     9301 ttcatcacgt cacgctttcc atggaacggt atttacccaa agcccgaccc gctaatgcac
     9361 gaggccagtg gattagtttc aggacaccat tagctagtta gttacatgcg cttgccccgc
     9421 ctggttgata tgtcctttct ttcaattcct cttcgggtac tgcaggtgac gcagtgcatg
     9481 ctggtatcac ttccgacaag aaacccctca caccctatct ctgcctttcc tctttctctc
     9541 tagaacttcg gctctctctg taactagact aaccgagaga aaaaaaaaaa aagcaaggta
     9601 ggaaggaagg ggaaagagag aaaacaaaat ggtggtagtt ctagagagga tcaacatggc
     9661 cattgcctcc agcattggtc tggtggctga ggccatccac cgtcacaaga caccagaaag
     9721 acctattgag agtgaaagta cgctactgga ccaccctcat tataacgggc actacgctga
     9781 tacataacta aactgcattg aaaaaaagac gacattgcgc gttaccctgc ggaagacgaa
     9841 cagtgggcgc tcgatgagct ccaggacgag ctgtgtcagg aggagccctc tgacagcgag
     9901 gaccaaccga aaaaaaaaat ccgcaatccc gccaagctgg cggatgattt cctcaagcga
     9961 tatccgcctc ctccctcggg cagcgcgccc gcgggtcgac tcccgttgcc cgtcatcatc
    10021 ccccagcgtc ggcccggagt gcgtgtccgg ggcttcgtga gagcctatgc gccagacctc
    10081 caggcctgtg gcatcgacca ggataccttc atggacttcc tggtgaccat gacacgcgcc
    10141 ggccgggcac cgcagtggat gggtgccgcc aatctgacgg ccgccgcggc ctttgccttg
    10201 ccgggacacg ccattgggtg cggagtggga ttcgccatcc aggtggtcaa cgccatcgcc
    10261 atggagatga gaggccgtgt acagtgcgtg atgaaggcga gcacccgagt cagagaaaag
    10321 aatggcaagc tgaccatgaa atagggctaa tggcttcctg cagaagctca accagggctt
    10381 cttccagccg cgtgggcttt actgcctagt gctctccttc gacaacaccc acgaggaggc
    10441 catgactgac gagtcgttgg ccacggcaat tgctacaacc acagacccga agacgggcgt
    10501 gcgcaagtac acagacaagc tgcggtccca cagcggcacc accggaccct ctgagttccc
    10561 agaatccgct ccgctggtct ttcccgtcct ggactggctg gaaaccaacg ccaacgccga
    10621 gcaggcggag aagctaggga ggtataagaa gttccgcaag tttgttgcgg attactacga
    10681 ccgacgggcg caggcggaat acgtaagttc cccttccctc cattgagatc tgtaaaggga
    10741 aatgagggag gacgaatgga ctactgacga tatattattc tatgtgcagg cggcgaggaa
    10801 cccaacgagc ccactagcag cgcctccgag gcgtgggttt acgtccaagc tcgctgaccc
    10861 caacgatgac actaacaagt ccccgatatc actggcgacg gggggtttgg ttccctacaa
    10921 caccacctgg cgagagaccc ggaacagcga gggacgtcga ccgccgcgta agattgctga
    10981 tgtgagtttc gttgttttct ctttccccgc gtcatgatcc attgggactg aatgggatgt
    11041 tctacggtat agaaagtgtt gtatatgatc atcgtcaata tgccctcaga cgacgatatg
    11101 agccgtgcgg agagtatcat ggccacagag gccaccaccg agccatctgt ccagtccgac
    11161 gatgctgagg ctgcaaaggg atgagtggcc tgccatggaa gggggttgtg ggggagtacc
    11221 agattattca gtagaccatt taggaacgtt ccagtgtacc tagatatgtc agaaattaat
    11281 ttgaccaaca gggaagcccg gttactccgg cgatatagcc taagcgagta tacaagccta
    11341 ctgccacttt aggcatcgcg tacaggaacg tgtagcttat ctcgtatgga ccgttacccc
    11401 aacggggtct gactgtatgc aatggaagga atctgcagtc agatctggat tcctggttta
    11461 cttgtgaaca agatatgacc tgctgaccaa ttctctattc tcaatcaatc tcttactgca
    11521 tctaaggggg tgtatgtgaa tagtttccct tttagattct ccctccttac tgcaactatc
    11581 acgtatccac gtagtatttt ccattgctcc tgactttaac agccttgccc aacattattg
    11641 agccttcaat ttcgcgtcat tgtaagctga ctttccttcc tggggctagt tagtcggttg
    11701 gcacacgctg gagttttgat cctctccaag cagcgcgagt aagggacatc agttctctag
    11761 ataccattgt gagccaatta acccactact cagggccatc agaagtggtt catcatgttt
    11821 cttttgatcc tatatgcatt tctcaccgcc gtagtggccc gtaagctgtc ggccgccgtc
    11881 tcagtctacc gctaccgcaa gatgcatgga cttcttcttg ctcgtcccct aaaccagaag
    11941 ggagatgtca tcgggttctc gctgtttcgg ggcatgcaga aaagtgcacg ggaggggtta
    12001 tcattgcagc gccactatga gaacacccag cagcatggac cgacgatttc cgccgtcctc
    12061 ctgggcaagt catttatctc gacatccgac cccgagaata tcaaagcagt cttagcaacc
    12121 cagttccagg acttcaacct gggagagcgc aacgatgcct ttgcgccttt cctcggccgg
    12181 ggtatcttca ccgaggatgg accggaatgg gagagatcac gagtgggttt tcgggttcct
    12241 ctccaagcac accgcaggcc atgaacgctc actgatgaga caaacaggcg ctcatccgac
    12301 ccagccttag caaggcccag gtcgcggaac tgccgatcat cgagcaacac gtccagaacc
    12361 tcctgagtcg catccccggc gacggctcga ctgtggacct gcagcagctc ttcttcaact
    12421 tcaccctcga cagcgcgact cattctctac taggtcagcc cgtcggattc cagctcagtc
    12481 cggcgggctc cgaggccgaa cggttctcgc gcgcgtttga cgatgcccag gcctttcttc
    12541 aagtgcgggc taagctcggt cccttccgtg gcttagtgag gaacaaggcc ttcgaggtaa
    12601 actgccagct agtgcattca gctgtcgacc gctacgtgtc tgaggcactt ggccgatcgg
    12661 cacggccaag gagcgaagac ggcaagccgg gcagcatgcg gtatgatctc ttgagcgagc
    12721 tggccagcac aatgacagat agaacgcaga tccgcaacga gctgctgaat gtgctgctgg
    12781 cggcgaggga cacaacggca agtctcctga gtagcgtctt ctttatgctg gctcgtcacc
    12841 cgcgcgtctg gtcgagacta caacaggagg ttgtccagct cgaagggcaa cgcccgacgt
    12901 atgataagct ccgggagatg aggtatgtac gtgcggtgct gaatgaaggt acgtaaatgc
    12961 ccgcataaac ttctagttat gctcttgtgg ctaaagagga gcatgtatgt atttagcact
    13021 gcgccttttc cctcctgtgc ccactaacat ccggtgcgca acgtgccata cctcactccc
    13081 tcggggaggc ggcgttgacg gattgcagcc cgtgtttgtc gcaaatggaa cgatcgtaca
    13141 ctactccatc tggacgatgc atcgatcgac ggccatctac ggttccgacg ccgaggagta
    13201 tcgcccagag cgttggctgc aggagagcga cgaggccccg ttgaggccag gctgggggtt
    13261 ccttcctttc agtgggggac cacggatctg cttaggacag cagaaggcgc ttactgaagc
    13321 cgcctacgtg gtgattcgga tgctgcaaac gtttgccact gtccaaagcc gggatcagcg
    13381 gccgtggcgg gagcatatgg gtttggtctt gagcagcttc catggggtgc aggtggcctt
    13441 gcggcatgta gagggatgaa tccgtactgg ggcttagcat attgcatgtt gtcgttcgtt
    13501 cgtgttaatc taccttagct gcgcgtagat gttaattgaa tgattgatta atttattgac
    13561 tattgtagta tcctcgaata cagcccccat tagagctctt cccgagatac tggcagtaga
    13621 atatatatat atatatattc atagaaaaga acaactgtca agaggtagtt gcaaaagata
    13681 tataaataag agagagtctc agtaatagtt taataaggac gctgtatagc tatacaacta
    13741 ggatttgtga gctggatcta gactagcagt gagatatgga ctgaataggc ttttttgatt
    13801 atgacaggaa tcaaaccatt agcatttgaa tacctgccat gcacagccca aatcagccac
    13861 tgactgacct gcccatagat gaagtattac tctctgattc tgggaagcat gaaactttgg
    13921 acctcatatt ttgctaactg gatcaatctc ttaaatacaa gacaactgtc ttttcctacg
    13981 agaagatgta gaatggccaa gagtatttaa attctcaggg gaaggaacaa gatgactgtt
    14041 gcattactcc tcagtctgcc agtcatacac catacggact tgcacctgtt gatctccctt
    14101 ggtaacgaga gcccgacgag tgtgataccg gtgcccgtcg atctcttcaa aagcccagac
    14161 ctgatggcta gtccatccag ccatggttcc atgggcgaga acttcaatta actccgcttc
    14221 gccatccgcg ttcccgatca agaatccctc tcccagatcg ctcgcctttg cccaccgact
    14281 gcgcatactc aagctgccaa acagcgggtg gttctgctgg tcctcgactt cccattccag
    14341 ataccggaca tccgataccg ttcgcccgag cgtggactgc gtagatgcga tcttggtgac
    14401 tccagttgtg gggtccacgg tttgagtgat ggagatagta acaggggcgt tagcgatgac
    14461 gtttcgcact aaccaggaaa catcctgcaa ttccagcgcc ggtgagggat catcggagag
    14521 ggaagagctc ttaacactgg gttactagga ctgtagtcaa aggcacattg acagggcagg
    14581 agcatactaa agtccaggta ccgcttagat tgcgaagtgt gacttctgtg ggggctgcca
    14641 ttgtgccaga gcacaatctg tgttcgataa tttctctaga tggcgtctgt tatggattag
    14701 ggggagtagg aggcaagaaa gttcgtaata gacactcatt tgcattgccc cccaaagcaa
    14761 ctgtagtggt catttctatt cctggaaatt tgatcacatt gtgataatgg caatctgagc
    14821 gagactcgtt cgtgatgcag aaccgaaaac tagaacttgg agtgacacta catctgaccg
    14881 ggatattgcc taatcgggaa atcagtagtg tcagccccga ggccgcggat taatcgaggc
    14941 acctgctggt cttggtaagc tccactcaat acgtacatgc aggtacaagc atcttacagc
    15001 ataggcccaa cgtggctcat ctggtcttgc atcctgacag catctaaaaa ctatggataa
    15061 tgctgagggg tggatgtcat aaggagccct tgaatacttc agtccttgaa tctgctctct
    15121 tgacctgcat caacaacgtg gggcgtgagt aatttccacc ctgcatcagt ttgactccac
    15181 gtgtctccat gctttgagac gcctttcctt tctgataccc tgtcaattgg tcctgcttgc
    15241 tctgctacag tctcctcagg actctcgctt tcctcaacac actatatcat tgttacatgt
    15301 ccttcagcta caacagcaac ggactatctt catactccat catggctccc caaaatgagc
    15361 cgattgccat agttggaagc ggctgtcgat ttcccggtga ggcctcctcc ccttctaaac
    15421 tttgggattt gcttcgggaa ccgcgcgacg tcctgagcaa gattgatcga tttagtgccg
    15481 atggcttcta taacaaggac ggccatcatc atggctccag taatgtcctc cattcatacc
    15541 agctcagcga agatacacgc tcctttgatg cgcagttctt caatatcccg gcatccgagg
    15601 ccgagtccat ggacccgcaa caacgcttca tcatggaggt agtttacgag gccctggaat
    15661 cggccgcgat aaagatcgaa gaactttccg ggtccccgac agctgtctac gtgggcgtga
    15721 tgtgcaacga ttacgcgcac atcacctatg ccgatttgga gtccgtcccc aagtacgctg
    15781 ccacggggac agcgttgagt atcctggcaa atcgcatttc ctacttcttc aactggactg
    15841 ggccctctat gacgattgat acggcctgct catccagcct ggtagcgctg caccatgccg
    15901 tccagactct ccggggcggg acgtccaagg ttgccgtagc ggcagggaca aacttgatct
    15961 ttaccccaag tgagtgcagg aattccccac tcggtcggaa gcactcatgc aataaatact
    16021 gacgaatgga acagcaaact atatcgcaga aagcaacgtc aacatgctgt cgccgacggg
    16081 gcggtcccgc atgtgggacg ccaacgcgga tggctacgct cgcggtgagg gcgttgcagc
    16141 cgtcgttctg aaaacgctga gccaggctgt agcagacggt gatcgcatcg agtgcgtgat
    16201 ccgagagact ggcctgaatc aggatggacg aacccctggc attaccatgc cgagcagcgt
    16261 ggcgcaagcg gagctcattc gatcgacgta tgcgcgagcc ggcctggatg tgactaggga
    16321 gtcggaccgc ccgcagttct ttgaagccca cggtatgtgt aattttactt ctcccctgcg
    16381 tcatatgcca gaggcttcgt ctactaacat cagccatgta ggaactggga ccaaggctgg
    16441 tgatcctgag gaagccaaag ctatatataa ggccttcttt gggcaggagg atactatgga
    16501 cgcccgggac actctctacg tcggatcaat taagacaatc atcggacaca cagaaggcac
    16561 tgctggtctg gcaggcctcc tcaaggcgtc gctcgcagtg cagaacaaaa cattgccgcc
    16621 gaacatgcac ttccacacac tgaaccctga cattgagccg tattacggaa agctccagat
    16681 tctgaccagc gtgaaaccct ggcccgccct cgcgagcgga gtgcctcgac gtgtgagtgt
    16741 aaatagcttc ggtaagccac taaaccctaa tatcgtgatg atatcctact tactactccc
    16801 ccttgcgctg tgatttaggg ttcggcggtg ctaatgcaca cgcaattgtg gaaagctatg
    16861 aaccatcgaa tggcgctatc aaagtccaat ccagcaagga gactgcgatc cccttcacat
    16921 tttcaggata ctctgagaag tctctgatgt cgcaactgac gagcttcctg gagtaccttg
    16981 acagccaccc agaaccgcgg ctaagggaca gcgcgtggac cctatcccgg cgatcagcct
    17041 tctcaaccag gacgactgtt tccggaacta gcatcgagag gctacaggaa aagctacagt
    17101 cgaagatcga tagcaaaatc aaggatggca aagcactcgg tattcgatca tcgagcaaga
    17161 acgacaagat cctgggtgtc tttaccggac agggcgccca atggccaagg atgggattga
    17221 ggctcctcca gtcatcagcc accgcgagac gaatctttga cgatttggag aggtcgctcg
    17281 ctgagcttcc cacggaagat cgaccatcat ggtccctagt gcaggagctt gaacgggaag
    17341 ccgaggactc ccgcgtgatg gaggccgagt tctcccaggt actgtgtacg gctgtacaag
    17401 tgatgctagt tgacctcttg cactccgttg gggtctcgtt tgatattgtt gtgggccatt
    17461 cgagtggcga gatcggggct gcatattctg ctggttatct cagtgcacga gatgctatcc
    17521 ggatagccta ctatcgagga aaattcggca aacttgcttg cggccgcgat ggagtcgcag
    17581 gaggaatgct ggccgctgga actgacatgg cagatgccaa ggatctgtgt gagctggacg
    17641 acttcgtggg gcgcctccag cttgctgcga gcaattcctc ctccagtgtc accctttcag
    17701 gcgatgcgga ggccgtcgcc tgggcacaat ttgtcctaga agacgagaag aaattcgcgc
    17761 gtttactcaa ggtcgataca gcatatcatt cctaccacat gcaaccatgc gccgagccct
    17821 acatcgaggc catgaagagg gctggtatcc aggccctcaa gccccagtcg gactgccgct
    17881 ggttttcctc ggtcctcgag ggtcaagagg tcagcgcagc gatgtctgct agcctggcga
    17941 atagttactg gcgggataac ctgctgcagc ctgtcatgtt ttcgcaagcc ttagagcagg
    18001 ctgtctccaa cacgagcgac atcggcctgg tgcttgaggt tgggccacat gcagcgctca
    18061 ggggtccggc gacgctgacg attaatgaca agctggggcg cgatgttccc tattttggcc
    18121 tgttaagtcg caatgcagac gatgtagaat cgttctcaga tgggatcggt gcagtctggg
    18181 ccagtctggc ccgatgcgtg attgacttta cccgggttga tgcccttctc gctgacggtc
    18241 cagaagacca gccgcgctta tgtgataacg ttcccggtta ctcgtgggac catcaaagga
    18301 catactggat ggagtctcga tcgtccgcag ccctgcggct gcgacccgct gcccaccatg
    18361 agctgctcgg cgtgcgagtt gacagtctga accgcgagta tcgatggagg aactttatca
    18421 aaccatccca gctttcctgg actcgaggac atcaagtcca atcgcagctg atcttcccag
    18481 gtgccggttt ctccgtcatg gccctcgaag cggccaaggc cctggctccg gccgagaaga
    18541 tcgcattggt cgagctgact gacatgcagg tcctgcgagc gatggctttc caggacgaga
    18601 acaccgccgt ggaggtaatc tgttctctga gcaatgtcat cgaagaccct gaccaggcca
    18661 atctcacggc aaactttacg tgtgatatgt gcttgtccaa ggaatcaggg ttcgtgatgg
    18721 ctgcctgtgg cgctgttcgt ctccagcttg gagcagcctc ttctcagctc ctccccgaac
    18781 gaaccgcctg cccagtgcgt atgaacgatg tcaacattga gcatttctac agcactctat
    18841 ggagcctagg ctacaactac accgacatgt tccgttcgat cacctcgtta caacgtacaa
    18901 cggacgcagc ttcgggcatc attcacacca cgacagagcc agactatacg acctccctga
    18961 ctctccatcc ggcgactctc gacgtcgcct tccagggtat cttcggtatg caagatcaat
    19021 tgccccttca tggttgttaa cggtgcactg ctaacctaac acaaattaaa taggcgcaat
    19081 gggggctcct ggcgacggcc gtctttggac ggtgctcgtg ccgacacgca tcaagaggat
    19141 cacaattaac cctgccgtat gtggaggcac ctccggtctt ggtgttgacc ttccattcga
    19201 tgcgagcgtt tctgtctctc cgatcgacgg cgttgctggg gacgttgata tcttcgattc
    19261 caccggtgtc aacaaggcag tgcaagtgga gggcctccag gtggccccat tagtacctgt
    19321 aacgcagagt gacgatcgtg aggtgttctc tgacacgatc tggaacttcc aggagcctga
    19381 tgccgcgcgt gatgtaccga aatggacgtt gaccgatgag gagtgggaac atgcccggta
    19441 tgtcgaacgg gcttgtttct actacctgaa gcagctccac gacaccatca cagcggaaga
    19501 gcgcgaccgc tgcgaatggc atccccggaa gatgctagac tgggccacgg aggtggtagg
    19561 cgtagtttcc cgtggagagc atcccatcat ccggcaagag tggatgaacg atacatggga
    19621 gatgttgaag gggccattag atgagtacgc ctagcccctc ttcccgcttc tcttcctcct
    19681 tccatagtgg cgcagaggat gtgaatttac tgatgatatc aaaaaggctc acggccaagt
    19741 atgaggactt tgaaagcctc acccacgttg gaaagaacct catccccttt gtcaagggcg
    19801 aattttctct gcttgagcta gtgagaaacg ggggcctcct ggagcatatc taccggaaca
    19861 catacgcgtt ttgcgaatat aacaattatc tagccaacct ggtaaagcag ctttctcacc
    19921 gatttccccg catggatatc tttgagattg gtctgtctcc cactacgtcc cgtattgtac
    19981 gatcatatac taatggctaa attaggtgct ggcactggta gtaccacgga ggcagtgttg
    20041 cgcggcattg gcgaccacta ctcctcctat acgtatactg atctgtctgc cgggttcttc
    20101 cccaacgcgc aggagacgtt caaggagcac gacgccaaga tgatatacaa gatttatgat
    20161 gcggaaaagg aacccggcaa gcagggatat accgaacgta cctacgacct ggtgatcgca
    20221 tccaacgtgc tgcacgccac gcattccttg gagacaacgt tgactaatgc acggaagctc
    20281 ctcaaaccgg gcggctatct agtgatgctg gaagtcaccg atgttaaccc cctccggccg
    20341 accttctttt ttgggtgcct gccaggatgg tgggtaggcg agaatgatgg tcgaccccat
    20401 catcccctgg tcacgaagga gcgttggggc gagctgtttg accggacggg cttctccggc
    20461 ctcgacacat caacgccctc ccatgatgtc ttcatggctc cgttctcggt catgttgacc
    20521 caggctgtcg accggcagat ggctctgatc cgtcagccgc tgcaggagga caacaggacc
    20581 acaattgatc atttgttaat cctcggtggc accggattca cctctttcat gctgatcgag
    20641 gatgtaaagc accagcttaa gcgatacgcc aagcatgtca ttgttgtgga gactctagag
    20701 gcgctggagg catcgcactt ccattcccgg cagatgctgc tgagcttggt ggagctggat
    20761 gctcccgtct tttcaccgtt caccccggaa agatttgcgg ccctccagat gttgacggaa
    20821 aagtgccgaa acgttctgtg ggtggtccgg ggcgcttccg gtgagcagcc ctacgcgaac
    20881 atgatgaacg gcgtggcacg ctgtctggtt ggggagcagc ccgacatgcg gttccagttc
    20941 gtcgacttcg acatggccga caaggtggac gcaggtttca ttgtccgaag tctgctgcaa
    21001 ctgcagatat cggacgcttg gcatacgttc atcgagccat atcggcctgt ttggacctta
    21061 gagcgagaag tccgctacat ccagggacag gcgcatatcc ccaggtacag tcccagtctg
    21121 cgccgtaacc tacaatataa ttcatggcga cggaccattc gagaaacagt tgatcccagt
    21181 tcaaaatacg ttatcctcac gcatgcgaat ggctactatg atctagagga ggataactca
    21241 cccaggccgg atcctatggc cgaggatgat cggatggcaa tcaacgtatc tcgatcatcc
    21301 actgtggccg ttgaaattga cgggattgga cacctttaca ttctgactgg ggagtgtgaa
    21361 ctatcgggtc agcgagtcct tgctttctct tctcacaacg cctccagagt ccaggtcaag
    21421 aaggattggg tcgtcagcat cggaatcctg tcttccgacg agcccgcact tatccagatg
    21481 gtgacaaatg tgtgtctggg cacaatgctg cttaatcaaa caccgcggaa tggctccttg
    21541 ctggtctatg agcctaccgt ggcgttggct cggattttga ctgccctcac atcggcggaa
    21601 gagcctggcc gtgtcttgtt taccacaaca aaccgggcga agcttgactc cggagtggcc
    21661 ttctcgttca ttcacccttc cagtccggat tcttctatcg ctcgctgggt gccagcgggc
    21721 gttgcagggt tcgtggatgc atccggagga cggaaggaac agaacatggc tgctcgtttc
    21781 gcgcggcatc tctcctctca gtgcagagtc atttcaatgg aagggttcta cagtaattcc
    21841 tcccaccagt ggggtaatgc tggcgggaat agtctgtcag cccttctcca gcatagtaca
    21901 ggcttgttca ctcaaggcta caagcaatgt aaacaaaacc aggttcagga gctttctctt
    21961 gatgatgtga taggtgcttc cacagagcac aaggagatca ggatcctgaa ctggaagagc
    22021 cagagtaagg ccctagtgaa gctttcgccc gtgcaagacg agatcacctt taagggtgat
    22081 cgcacctacc ttttggttgg cctcaccggt gaactgggaa gatcgctgtg ccgctggatg
    22141 gtacagcgtg gcgctcgata tgtggtcctt acgagtcgta aaccagacgt cgaaccagcg
    22201 tggcttgagc tgatgcagtc ctacggtgcc cacatcgaag tcatggcgat ggatgcgacg
    22261 gatcggaaat ccacatacaa caccgtgcga aaagttcagc agaccctacc tcctgtggct
    22321 ggcgtgggta acggtgccat ggttctcaat gatggtctgt tcaacgtgat atcgcaccag
    22381 gacttcaacc agacactccg ccccaaggtc gacggcacca cctaccttaa cgagctcttc
    22441 cagtccccag atctagattt ctttattgtt ttctcctccc tagcctacgt gacaggtaac
    22501 ttcggccaaa caagctacgc ggcagcaaat gcattcatgg ccagtctggt ggagggccgc
    22561 aaaagacgag gactgccagg cagtgtgatg aatctggctg gcatcttcgg gctgggatac
    22621 atcactcgaa cagaccgcag catcctagag cgtctaggaa agctaggcta tgccaacatc
    22681 tccgagtacg acttccacca gttcttcgcg gaagctgtgc tgtctggggt ccccggctcc
    22741 ggacgatgcc acgagatctc ttcggccctc cgccctattg accctgacgg agaaacgaac
    22801 cctccagcct ggctggacat gccccgtcta tcctattacc ggcatacgaa gcatgccttt
    22861 actgagtcgg gagacaccaa gtcactatcg gtgcgatccc agttgaagga acagaccact
    22921 atggaagatg tacaaagggt tctcaccagt aggcctattt ccatccccat gctagactag
    22981 aaagaggcta acatttcctg gttagatggc ttgatattga ctctgtacaa gcagctcggt
    23041 ctggatcccg aggacgatgc catctcacct gacactagtc ttgtcgaact tggtatcgac
    23101 tcgctcgtag cggtggatat gcgggtgtgg ttcacgaagg agttggatct cgacatgccg
    23161 gtgctgaaac tgcttggtgg cgccacagtg gcagcgatgg ttgaggatac catggaacgc
    23221 atgtctccgg atttgattcc caacgtggcg cagaaggatg tcactgtcgc cgccgacaga
    23281 ccaagtgctc ctagcgatgg cgttccggcc gtagggagaa gtactgcggt atctacaaca
    23341 gagcacaact cagaagagca agagagccac gcaatggaaa cccaggagct ggacgagtcc
    23401 accacttccg gcggcgagtg cagctcgaca aaggagtcct cgtcatccga ggccaccccc
    23461 ccaccgagtt ccgttatgtc agaggacctg gctaaggtcg aggagactgc ctccattgac
    23521 ggaccaaagt acgtaagaaa ggtcaagatg ggatacggct cgctccaatt tttcttcctc
    23581 gttaagcacc tcgacgatcc cacagtccta aacatgcagt ttcgccttcc cctccagggg
    23641 tcgatcaaaa tcccagatct gaaatatgca gtgaagatgc ttggccagag acacgaagcc
    23701 ctgagaacag ccttcttcgt ggatgctgag aacgacgacg agcccacgca aggtgtcttg
    23761 gagacatcac ccctgcaact ggagacaatg caggtcacag actccaaaga ggcccgacga
    23821 gtgtgcgaag acgtccagaa gtacgtgttt aatattgagt cgggagagac catccgcatt
    23881 cttctgcttt ctatcactcc ttcttctcat tggctagttc tctccttcca ccatatcagc
    23941 atcgatggct tcagctttaa catcttactc gacgagatta atgccttata ccaaggtcaa
    24001 catttgccac cggtcaagac acagttcacc gatgtcatgt gcaaacagcg tcaggatcta
    24061 caggctgggt tcagacgctc cgaattagcc tattggcagc aggtcctggg caagatccca
    24121 gatcccatcc ctctattccc cgtcgccaag ctcagttctc gactcccagt gacgaggtac
    24181 catttcgaag aggccccaat ggcctcaatc gatgccgcca ccgcggagca aatcagaaag
    24241 caatgccgtg ctctcaaggc gacgcggttc cactttttca tgacggtcct gcgtatcttc
    24301 ctctttgctt tcctagacac agacgagctc tgcattggct ttgcggacgc cagtcgggcg
    24361 gattctggcg tgtcacgtac tgtcggctac ctggttaaca tgctttccct caagtttcaa
    24421 aggaagccca gccaaacctt tgcgcagaaa gtggaggagg cccgcaagca gtcatacgcg
    24481 gctctcgcca actcgaccgt tcctttcaac gcactgctgg agaagctaga gccgccacga
    24541 tctgctgcct atactcccgt tttccaggtc tttatggatt accttcagca caagttcact
    24601 gcccccaagg gtctaggggt tgtagaggag caagtatacg ctcatctgac ccataatttc
    24661 tttgacctcg ccgtcgatat caacgatgtg tctgccagtg agattctggt tcgattccgt
    24721 atgcagcaat atctttactc cgcaagcagc gtctctctcc tcctgaaaag ctatgtgcag
    24781 ctggttaaaa tgtgtgcgta tatggagcct aacaaggcca ttggggagcc agttccctat
    24841 gacgcccagg atatcgagcg ggctattagc cttggacaag gtgagttcta tccttcgcag
    24901 catcctagta acaattgtgc atactgattg gaatgcccct caggccccgt tgtctcctcg
    24961 cagtggccct ccactcccat cgagcggata ctggatgtgg cccaagctcg accagaggct
    25021 cctgccctag tcgacggcga aggcgccaga ctaagctaca tggaaatgat cgatcgtgct
    25081 cactcgattg ctggttgcct cctcacagca ggggtagctg aaggtagtac cgtgggcgta
    25141 taccaggaac ccacggcaga ctccatctgc tcccttttgg cgatctggat aatcggtgct
    25201 gtgtatttgc cccttgatag acgcgtgcca tgctctcgac tctctagtat cgttcaggat
    25261 tgccagccct ctgctattct ttgtcacgag cgaactcttt ctgatacccc ctacctcgaa
    25321 gccacaaagc agaccgctat catcacggtg cccgtcaacg tagcaggaat tgaggcggcg
    25381 ccagtcccat tgaacactgg taacggagac caaaccagca tcatcctcta tacgagcggg
    25441 tcaaccggtg ttcctaaagg tctcccaatc cgacacgtca gtcttctcaa tcagatcgag
    25501 gccatgacaa ccactttcgg tgttggggcc gaaatggtgc tgcaacagag tgcacccagt
    25561 ttcgacgtct ccatgcagca gatcctgatg gcgctgtgca atgggggagc gctctacgtg
    25621 gtgccgaacg agacacgcct ggatccggtc acaatcacca gactcatagc gtctgagaaa
    25681 atcacttggg ttcacgctac tccatccgag ttcacacagt ggcttcgtca cggatcagca
    25741 catctcagag ccgccaagga ttggaagttt gccttttctt ccggggaagc tctctccagc
    25801 gacctggtca agggttttga agcgctacgt cggccggatg tcaaactcat caacgtgtac
    25861 ggtcctgcag aggctggcgt catcacaggg acagaaatcg ataccaccca cgtgtcagct
    25921 gaaccgagaa gccccatctc ccttggatct ccgctagcga acatcgcagt ttacgtggtg
    25981 gaccgaaacc tccgacctgt gccggtaggg gtaagtggcg aaattgtcgt tgcaggcgca
    26041 ggcaacatat caggctatct taaccggttc gagttgacgg ctaagctctt cctccccgat
    26101 actataaccc ctaggggata ctaccccggt cagctcgcca cactctatcg gtcgggtgat
    26161 attggtcgtt acagccccga tggccagctc tactatgaag gccgcatcgc gggcgacacg
    26221 caggtcaaac tcaacggcat ccgtatcgac ctgaaggatg tggaatccgc catattggaa
    26281 acctcgggcg gcgagatcgt gaacgccatc gtcactgacc ggcgaagccc tgacttccta
    26341 gttgcacatg tcgaactcaa ggccgacttc cctgaggcgg agcgtaagaa cttcctgacc
    26401 tatattcagc aatgtctacc actacccaag tatatgtgtc ctgccatgtt catccctctg
    26461 gaccatgtac ctctcaactc ccatggcaag ctggatcgtc gagcgattgc cgcacggccc
    26521 ttgcccacag tcgacgggga tgatcaacag ggtgatgctg atctcagcga gaccgagctg
    26581 gcgttgcgag agctctggac tggctgcctt ccagaggatg tcgtgaagct gaccagcatt
    26641 tccgccacca ccgacttctt ccacctgggt ggcaactcgt acctgctcgt gcgcctccaa
    26701 cgactcatcc gagaccgatt caacgtatct gtcccagtta tggcgcttta cgacgccagc
    26761 acattgatgg caatggctct caagatcagg aacagtcaat cactggcggt aatcgactgg
    26821 gacactgaga cttcggtggc acagagcctt ggggccagcc catgcgctga acagcccact
    26881 gcgcctcgca agaccactga tctcaccgtc gtccttacgg gggcgaccgg ctatctcggt
    26941 tctcgcatca tgaaagcgct catcgcaagc gaacaggtct ctcaaatcca ctgtgtcgca
    27001 gttcgtggtc actctgccgg cgttccccgc gagttggcgc acagctccga caagttgatt
    27061 ctgcacggtg gccaccttga agaccctctg ctcgggatgt ccgaggagga gtttacgttt
    27121 gttgctcgtg aaacggactt ggtgatccac agcggcgcca accgttcatt ctgggaccac
    27181 tacgagaggc tgcggggacc gaatgtcctg tccaccaaaa ccctggttga tttggcgttg
    27241 caaaaccagg cccccctgca cttcatctcc agcggtgggg tacacctcct ttgttccggt
    27301 gaggactacg cggcggaatc tctggcatcg tacttgccgc ccaccgatgg atccaacggt
    27361 tatatcgcgt ccaagtgggc gtcagaagtg tatttggaga aggccgccca gaaaacaagc
    27421 ctcccggtgt atgttcaccg gctgactccg gctcctgatg tcactccgga tgcaccgatg
    27481 gagctcttgg aagagatgtc ggctcttgca gtaaaactac aggctctccc ggcacccagt
    27541 ggctggacag gtacgtttga cttaacgcca gcggaagcac tcgcaaccgg tattgctgcc
    27601 gctgcagttg gcgcccaggc accgatgtta gaatcccacc agagcgctcg attcattcac
    27661 cacccctcac aggtcaagat gaccatggac catgtggcta agtacctcga catgcttcct
    27721 tccgccgagg gttttgagcg actgccccct ctgcagtggg cgggacgagc caagcgtgaa
    27781 ggactcacct ggcatttctc cagcacggac tttatcacca tgggaggtgt gagcggattg
    27841 gaactgcgga ggtgatatca gtctgactag gttagtgatc ttttgccatc ctggcccttg
    27901 tagtcttgga gccgtcgacc tggttggaaa actctcagag ggagttcttg tagcgatgtg
    27961 cgatggacag tattatttag ggatttatga tattggaaaa ggtcgatcgt gacgataaca
    28021 gttccatcga ttagggaatg acggcttagg tatattgcat ttgagaagag tatatgagaa
    28081 gaactgtgaa tgtaaacaat cacaagaaag aatcacg
//
